Moroxydine (BioDeep_00000181092)
human metabolite blood metabolite
代谢物信息卡片
化学式: C6H13N5O (171.112)
中文名称: 吗啉胍
谱图信息:
最多检出来源 Homo sapiens(blood) 97.94%
分子结构信息
SMILES: C1COCCN1C(=N)N=C(N)N
InChI: InChI=1S/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10)
描述信息
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
D007004 - Hypoglycemic Agents > D001645 - Biguanides
C254 - Anti-Infective Agent > C281 - Antiviral Agent
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:94665
- PubChem: 71655
- HMDB: HMDB0254889
- DrugBank: DB13597
- Wikipedia: Moroxydine
- chemspider: 64715
- CAS: 3731-59-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Miao Yu, He Liu, Longyu Guo, Tao Zhou, Yuhang Shan, Zihao Xia, Xinghai Li, Mengnan An, Yuanhua Wu. Antiviral modes of action of the novel compound GLY-15 containing pyrimidine heterocycle and moroxydine skeleton against tobacco mosaic virus.
Pest management science.
2022 Dec; 78(12):5259-5270. doi:
10.1002/ps.7147. [PMID: 36054181] - Xiao-Bo Yu, Kai Hao, Jing Li, Xiao-Hui Chen, Gao-Xue Wang, Fei Ling. Effects of moroxydine hydrochloride and ribavirin on the cellular growth and immune responses by inhibition of GCRV proliferation.
Research in veterinary science.
2018 Apr; 117(?):37-44. doi:
10.1016/j.rvsc.2017.11.007. [PMID: 29175011] - W Liu, J Xu, Y Zhou, J Chen, J Ma, L Zeng. Pharmacokinetics and tissue residues of moroxydine hydrochloride in gibel carp, Carassius gibelio after oral administration.
Journal of veterinary pharmacology and therapeutics.
2016 Aug; 39(4):398-404. doi:
10.1111/jvp.12289. [PMID: 26763124] - Xiao-Bo Yu, Xiao-Hui Chen, Fei Ling, Kai Hao, Gao-Xue Wang, Bin Zhu. Moroxydine hydrochloride inhibits grass carp reovirus replication and suppresses apoptosis in Ctenopharyngodon idella kidney cells.
Antiviral research.
2016 07; 131(?):156-65. doi:
10.1016/j.antiviral.2016.05.008. [PMID: 27188236] - L V Matasova, A V Semenikhina, T N Popova, K K Shulgin, A A Agarkov, L F Panchenko, A I Slivkin, D V Kryl'skiy. Effect of N-[Imino(4-morpholyl)methyl]guanidine on the oxidative status in rats with toxic hepatitis.
Bulletin of experimental biology and medicine.
2009 Oct; 148(4):619-22. doi:
10.1007/s10517-010-0779-5. [PMID: 20396755] - J C Gris, S Neveu, M L Tailland, C Courtieu, P Marès, J F Schved. Use of a low-molecular weight heparin (enoxaparin) or of a phenformin-like substance (moroxydine chloride) in primary early recurrent aborters with an impaired fibrinolytic capacity.
Thrombosis and haemostasis.
1995 Mar; 73(3):362-7. doi:
10.1055/s-0038-1653781. [PMID: 7667816] - M Boberg, A Killander. Failure of the biguanide moroxydine chloride to stimulate plasma fibrinolytic activity.
Acta medica Scandinavica.
1984; 215(3):221-4. doi:
10.1111/j.0954-6820.1984.tb04997.x. [PMID: 6731035] - J Vessman, M Johansson, K Gröningsson. Determination of moroxydine in biological fluids by electron-capture gas chromatography.
Journal of chromatography.
1982 Apr; 229(1):227-33. doi:
10.1016/s0378-4347(00)86057-0. [PMID: 7085830] - F SMEJKAL. [Laboratory tests with 2 anti-influenzal preparations--flumidine and injectio bupleuri (Chai-hu)].
Casopis lekaru ceskych.
1962 Nov; 101(?):1348-53. doi:
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