Morniflumate (BioDeep_00000181090)

   

human metabolite blood metabolite


代谢物信息卡片


2-(morpholin-4-yl)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylate

化学式: C19H20F3N3O3 (395.1456686)
中文名称: 马尼氟酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1COCCN1CCOC(=O)C2=C(N=CC=C2)NC3=CC=CC(=C3)C(F)(F)F
InChI: InChI=1S/C19H20F3N3O3/c20-19(21,22)14-3-1-4-15(13-14)24-17-16(5-2-6-23-17)18(26)28-12-9-25-7-10-27-11-8-25/h1-6,13H,7-12H2,(H,23,24)

描述信息

M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent

同义名列表

7 个代谢物同义名

2-(morpholin-4-yl)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylate; Niflumic acid beta-morpholinoethyl ester; beta-Morpholinoethyl niflumate; UP-164morniflumic acid; UP-164morniflumate; Morniflumic acid; Morniflumate



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Hea-Young Cho, Geun-Kyeong Park, Yong-Bok Lee. Simultaneous determination of morniflumate and its major active metabolite, niflumic acid, in human plasma by high-performance liquid chromatography in stability and pharmacokinetic studies. Biomedical chromatography : BMC. 2013 Nov; 27(11):1438-43. doi: 10.1002/bmc.2940. [PMID: 23722315]
  • Jean-Pascal Fournier, Maryse Lapeyre-Mestre, Agnès Sommet, Julie Dupouy, Jean-Christophe Poutrain, Jean-Louis Montastruc. Laboratory monitoring of patients treated with antihypertensive drugs and newly exposed to non steroidal anti-inflammatory drugs: a cohort study. PloS one. 2012; 7(3):e34187. doi: 10.1371/journal.pone.0034187. [PMID: 22479557]
  • J L Stéphan, I Koné-Paut, C Galambrun, R Mouy, B Bader-Meunier, A M Prieur. Reactive haemophagocytic syndrome in children with inflammatory disorders. A retrospective study of 24 patients. Rheumatology (Oxford, England). 2001 Nov; 40(11):1285-92. doi: 10.1093/rheumatology/40.11.1285. [PMID: 11709613]
  • M Civelli, T Vigano, D Acerbi, P Caruso, M Giossi, S Bongrani, G C Folco. Modulation of arachidonic acid metabolism by orally administered morniflumate in man. Agents and actions. 1991 Jul; 33(3-4):233-9. doi: 10.1007/bf01986568. [PMID: 1659152]
  • P Schiantarelli, S Cadel, D Acerbi. A gastroprotective anti-inflammatory agent: the beta-morpholinoethyl ester of niflumic acid (morniflumate). Agents and actions. 1984 Feb; 14(2):247-56. doi: 10.1007/bf01966649. [PMID: 6608862]
  • G Houin, F Bree, J P Tillement. Quantitative determination of niflumic acid and its beta-morpholinoethyl ester in human plasma by gas-liquid chromatography. Journal of chromatography. 1981 May; 223(2):351-6. doi: 10.1016/s0378-4347(00)80107-3. [PMID: 7251789]