1-(cis-13-Docosenoyl)-rac-glycerol (BioDeep_00000181066)
human metabolite blood metabolite
代谢物信息卡片
化学式: C25H48O4 (412.3552408)
中文名称:
谱图信息:
最多检出来源 Mus musculus(blood) 2.78%
分子结构信息
SMILES: CCCCCCCCC=CCCCCCCCCCCCC(=O)OCC(O)CO
InChI: InChI=1S/C25H48O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(28)29-23-24(27)22-26/h9-10,24,26-27H,2-8,11-23H2,1H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Besma Abbaoui, Kenneth M Riedl, Robin A Ralston, Jennifer M Thomas-Ahner, Steven J Schwartz, Steven K Clinton, Amir Mortazavi. Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin: characterization, metabolism, and interconversion.
Molecular nutrition & food research.
2012 Nov; 56(11):1675-87. doi:
10.1002/mnfr.201200276. [PMID: 23038615] - Ahmad F Abdull Razis, Natalya Hanlon, Ewa Soltys, Veronika Krizova, Renato Iori, Kathryn E Plant, Nick Plant, Costas Ioannides. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.
Archives of toxicology.
2012 Oct; 86(10):1505-14. doi:
10.1007/s00204-012-0875-6. [PMID: 22643862] - Ahmad F Abdull Razis, Manuela Bagatta, Gina R De Nicola, Renato Iori, Nick Plant, Costas Ioannides. Characterization of the temporal induction of hepatic xenobiotic-metabolizing enzymes by glucosinolates and isothiocyanates: requirement for at least a 6 h exposure to elicit complete induction profile.
Journal of agricultural and food chemistry.
2012 Jun; 60(22):5556-64. doi:
10.1021/jf3011195. [PMID: 22594452] - John D Clarke, Anna Hsu, Ken Riedl, Deborah Bella, Steven J Schwartz, Jan F Stevens, Emily Ho. Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.
Pharmacological research.
2011 Nov; 64(5):456-63. doi:
10.1016/j.phrs.2011.07.005. [PMID: 21816223] - John D Clarke, Ken Riedl, Deborah Bella, Steven J Schwartz, Jan F Stevens, Emily Ho. Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement.
Journal of agricultural and food chemistry.
2011 Oct; 59(20):10955-63. doi:
10.1021/jf202887c. [PMID: 21928849] - Natalya Hanlon, Nattaya Konsue, Nick Coldham, Maurice J Sauer, Costas Ioannides. Exposure to isothiocyanates suppresses urinary mutagenicity in rats treated with heterocyclic amine IQ: lack of association with CYP1 activity.
Nutrition and cancer.
2011; 63(2):300-5. doi:
10.1080/01635581.2011.530735. [PMID: 21298592] - Ren-Hau Lai, Michael J Miller, Elizabeth Jeffery. Glucoraphanin hydrolysis by microbiota in the rat cecum results in sulforaphane absorption.
Food & function.
2010 Nov; 1(2):161-6. doi:
10.1039/c0fo00110d. [PMID: 21776467] - Evelyn Lamy, Julia Schröder, Stefanie Paulus, Peter Brenk, Thorsten Stahl, Volker Mersch-Sundermann. Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (HepG2) cells towards benzo(a)pyrene and their mode of action.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Jul; 46(7):2415-21. doi:
10.1016/j.fct.2008.03.022. [PMID: 18479797] - Radha M Bheemreddy, Elizabeth H Jeffery. The metabolic fate of purified glucoraphanin in F344 rats.
Journal of agricultural and food chemistry.
2007 Apr; 55(8):2861-6. doi:
10.1021/jf0633544. [PMID: 17367161] - Jessica Barillari, Donatella Canistro, Moreno Paolini, Fiammetta Ferroni, Gian Franco Pedulli, Renato Iori, Luca Valgimigli. Direct antioxidant activity of purified glucoerucin, the dietary secondary metabolite contained in rocket (Eruca sativa Mill.) seeds and sprouts.
Journal of agricultural and food chemistry.
2005 Apr; 53(7):2475-82. doi:
10.1021/jf047945a. [PMID: 15796582] - Rex Munday, Christine M Munday. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds.
Journal of agricultural and food chemistry.
2004 Apr; 52(7):1867-71. doi:
10.1021/jf030549s. [PMID: 15053522] - Lingxiang Ye, Albena T Dinkova-Kostova, Kristina L Wade, Yuesheng Zhang, Theresa A Shapiro, Paul Talalay. Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans.
Clinica chimica acta; international journal of clinical chemistry.
2002 Feb; 316(1-2):43-53. doi:
10.1016/s0009-8981(01)00727-6. [PMID: 11750273]