Methylhydrazine (BioDeep_00000180893)
human metabolite blood metabolite
代谢物信息卡片
化学式: CH6N2 (46.0530956)
中文名称: 甲基肼
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNN
InChI: InChI=1S/CH6N2/c1-3-2/h3H,2H2,1H3
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 6061
- HMDB: HMDB0254650
- ChEMBL: CHEMBL160520
- MeSH: Monomethylhydrazine
- CAS: 20244-39-7
- CAS: 60-34-4
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Manish P Ponda, Zhe Quan, Michal L Melamed, Amanda Raff, Timothy W Meyer, Thomas H Hostetter. Methylamine clearance by haemodialysis is low.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2010 May; 25(5):1608-13. doi:
10.1093/ndt/gfp629
. [PMID: 20019016] - R L Nelson, H Abcarian, T M Nelson, A Misumi, H Kako, S Rizk, H Sky-Peck. The effect of dietary selenium deficiency on acute colorectal mucosal nucleotoxicity induced by several carcinogens in the rodent.
American journal of surgery.
1996 Jul; 172(1):85-8. doi:
10.1016/s0002-9610(96)00067-0
. [PMID: 8686809] - P Slanina, E Cekan, B Halen, K Bergman, R Samuelsson. Toxicological studies of the false morel (Gyromitra esculenta): embryotoxicity of monomethylhydrazine in the rat.
Food additives and contaminants.
1993 Jul; 10(4):391-8. doi:
10.1080/02652039309374162
. [PMID: 8405578] - C P Siegers, D Bumann, H D Trepkau, B Schadwinkel, G Baretton. Influence of dietary iron overload on cell proliferation and intestinal tumorigenesis in mice.
Cancer letters.
1992 Aug; 65(3):245-9. doi:
10.1016/0304-3835(92)90239-r
. [PMID: 1516040] - K Bergman, K E Hellenäs. Methylation of rat and mouse DNA by the mushroom poison gyromitrin and its metabolite monomethylhydrazine.
Cancer letters.
1992 Jan; 61(2):165-70. doi:
10.1016/0304-3835(92)90175-u
. [PMID: 1730140] - K J Dennis, T Shibamoto. Gas chromatographic analysis of reactive carbonyl compounds formed from lipids upon UV-irradiation.
Lipids.
1990 Aug; 25(8):460-4. doi:
10.1007/bf02538089
. [PMID: 2120528] - Y Fukushima, H Kon. On the mechanism of loss of deformability in human erythrocytes due to Heinz body formation: a flow EPR study.
Toxicology and applied pharmacology.
1990 Feb; 102(2):205-18. doi:
10.1016/0041-008x(90)90021-l
. [PMID: 2154065] - T Biegański, Z Osińska, C Maśliński. Inhibition of plant and mammalian diamine oxidases by hydrazine and guanidine compounds.
The International journal of biochemistry.
1982; 14(10):949-53. doi:
10.1016/0020-711x(82)90080-5
. [PMID: 6215274] - B Toth, K Patil. The tumorigenic effect of low dose levels of N-methyl-N-formylhydrazine in mice.
Neoplasma.
1980; 27(1):25-31. doi:
"
. [PMID: 7189581] - R Braun, U Greeff, K J Netter. Liver injury by the false morel poison gyromitrin.
Toxicology.
1979 Feb; 12(2):155-63. doi:
10.1016/0300-483x(79)90042-8
. [PMID: 473232] - E S Fiala, G Bobotas, C Kulakis, J H Weisburger. Inhibition of 1,2-dimethylhydrazine metabolism by disulfiram.
Xenobiotica; the fate of foreign compounds in biological systems.
1977 Jan; 7(1-2):5-9. doi:
10.3109/00498257709036240
. [PMID: 848043] - B Toth, D Nagel, J Erickson, R Kupper. Tumorigenicity of tetramethylhydrazine hydrochloride in Swiss mice.
Journal of the National Cancer Institute.
1976 Nov; 57(5):1179-83. doi:
10.1093/jnci/57.5.1179
. [PMID: 1034021] - G L Floersheim. [Viewpoints on the pharmacological suppression of immunologic reactivity].
Schweizerische medizinische Wochenschrift.
1975 Oct; 105(43):1373-81. doi:
NULL
. [PMID: 766172] - B S Reddy, T Narisawa, P Wright, D Vukusich, J H Weisburger, E L Wynder. Colon carcinogenesis with azoxymethane and dimethylhydrazine in germ-free rats.
Cancer research.
1975 Feb; 35(2):287-90. doi:
NULL
. [PMID: 162868] - W T Gormley. Distribution characteristics of methyl-hydrazine in the plasma and cerebrospinal fluid of monkeys.
Aviation, space, and environmental medicine.
1975 Jan; 46(1):64-8. doi:
NULL
. [PMID: 1115698] - A Hawks, R M Hicks, J W Holsman, P N Magee. Morphological and biochemical effects of 1,2-dimethylhydrazine and 1-methylhydrazine in rats and mice.
British journal of cancer.
1974 Nov; 30(5):429-39. doi:
10.1038/bjc.1974.217
. [PMID: 4469195] - G Hennighausen, B Tiefenbach, C Dietrich. [Studies on toxicological and pharmacological properties of chlorcholine chloride (CCC) and N,N-dimethyl-(2-bromoethyl)-hydrazinium bromide (BMH)].
Acta biologica et medica Germanica.
1974; 33(1):89-98. doi:
"
. [PMID: 4418892] - J RAAFLAUB, D E SCHWARTZ. [ON THE METABOLISM OF A CYTOSTATIC METHYLHYDRAZINE DERIVATIVE (NATULAN)].
Experientia.
1965 Jan; 21(?):44-5. doi:
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. [PMID: 14283528] - B A REYNOLDS, A A THOMAS. DETERMINATION OF HYDRAZINE AND 1-METHYLHYDRAZINE IN BLOOD SERUM. TECHN DOCUM REP NO. AMRL-TDR-64-24.
AMRL-TR. Aerospace Medical Research Laboratories (U.S.).
1964 Apr; ?(?):1-11. doi:
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. [PMID: 14151672]