Mertiatide (BioDeep_00000180755)
human metabolite blood metabolite
代谢物信息卡片
2-{[1-hydroxy-2-({1-hydroxy-2-[(1-hydroxy-2-sulphanylethylidene)amino]ethylidene}amino)ethylidene]amino}acetic acid
化学式: C8H13N3O5S (263.0576)
中文名称: 巯替肽
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(=O)NCC(=O)O)NC(=O)CNC(=O)CS
InChI: InChI=1S/C8H13N3O5S/c12-5(2-10-7(14)4-17)9-1-6(13)11-3-8(15)16/h17H,1-4H2,(H,9,12)(H,10,14)(H,11,13)(H,15,16)
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D019275 - Radiopharmaceuticals
同义名列表
7 个代谢物同义名
2-{[1-hydroxy-2-({1-hydroxy-2-[(1-hydroxy-2-sulphanylethylidene)amino]ethylidene}amino)ethylidene]amino}acetic acid; 2-{[1-hydroxy-2-({1-hydroxy-2-[(1-hydroxy-2-sulphanylethylidene)amino]ethylidene}amino)ethylidene]amino}acetate; 2-{[1-hydroxy-2-({1-hydroxy-2-[(1-hydroxy-2-sulfanylethylidene)amino]ethylidene}amino)ethylidene]amino}acetate; 2-{2-[2-(2-sulfanylacetamido)acetamido]acetamido}acetic acid; {2-[2-(2-sulfanylacetamido)acetamido]acetamido}acetic acid; GLYCINE, N-(MERCAPTOACETYL)GLYCYLGLYCYL-; Mertiatide
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 60778
- HMDB: HMDB0254471
- ChEMBL: CHEMBL1615778
- MeSH: Technetium Tc 99m Mertiatide
- CAS: 66516-09-4
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Hyeong-Joon Lim, Seok Hwa Choi. Assessment of Individual Renal Function Using 99mTc-MAG3 Renography.
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Clinical physiology and functional imaging.
2021 Nov; 41(6):488-496. doi:
10.1111/cpf.12724. [PMID: 34418886] - Anita Brink, Elena Libhaber, Michael Levin. Renogram image characteristics and the reproducibility of differential renal function measurement.
Nuclear medicine communications.
2021 Aug; 42(8):866-876. doi:
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Biomolecules.
2021 02; 11(2):. doi:
10.3390/biom11020263. [PMID: 33579037] - Takashi Kobayashi, Yuji Nakamoto, Takuro Sunada, Atsuro Sawada, Toshinari Yamasaki, Osamu Ogawa. 99mTc-mercaptoacetyltriglycine Cortical Renography Predicts Outcomes in Adult Living Donor Renal Transplant Recipients.
Transplantation proceedings.
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Physics in medicine and biology.
2020 11; 65(23):235026. doi:
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The Canadian journal of urology.
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Nuklearmedizin. Nuclear medicine.
2020 Aug; 59(4):316-322. doi:
10.1055/a-1139-9111. [PMID: 32227315] - Masato Kobayashi, Kodai Nishi, Asuka Mizutani, Hiroyuki Okudaira, Takeo Nakanishi, Naoto Shikano, Ryuichi Nishii, Ikumi Tamai, Keiichi Kawai. Transport mechanism and affinity of [99mTc]Tc-mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells.
Nuclear medicine and biology.
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2018 Oct; 39(10):921-927. doi:
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2018 Aug; 138(?):25-28. doi:
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Clinical nuclear medicine.
2018 Jul; 43(7):533-534. doi:
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Clinical nuclear medicine.
2018 Jul; 43(7):540-541. doi:
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European journal of radiology.
2018 Jun; 103(?):105-111. doi:
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Clinical and experimental nephrology.
2018 Apr; 22(2):453-458. doi:
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Journal of pediatric urology.
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PloS one.
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Urology.
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Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
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BJU international.
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Journal of pediatric urology.
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Journal of endourology.
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10.1016/j.urology.2014.08.041. [PMID: 25432830] - Rudolf A Werner, Christina Bluemel, Constantin Lapa, Dirk O Muegge, Theodor Kudlich, Andreas K Buck, Ken Herrmann. Pretherapeutic estimation of kidney function in patients treated with peptide receptor radionuclide therapy: can renal scintigraphy be safely omitted?.
Nuclear medicine communications.
2014 Nov; 35(11):1143-9. doi:
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Revista espanola de medicina nuclear e imagen molecular.
2014 Nov; 33(6):384-5. doi:
10.1016/j.remn.2013.10.014. [PMID: 24559938] - Sabina Dizdarevic, Mark Aplin, Melanie J Newport, Nicola Ryan, Stephen Holt, Stephanie Goubet, Lawrence Goldberg, Kenneth A Miles, A Michael Peters. Old tracer for a new purpose: potential role for 99mTc-2-Methoxyisobutylisonitrile (99mTc-MIBI) in renal transplant care.
Nuclear medicine communications.
2014 Oct; 35(10):1058-66. doi:
10.1097/mnm.0000000000000165. [PMID: 25025147] - Yasutaka Baba, Sadao Hayashi, Shunichiro Ikeda, Megumi Jinguji, Masatoyo Nakajo, Masayuki Nakajo. Evaluation of split renal function before and after renal arterial embolization for angiomyolipoma using absolute ethanol.
Cardiovascular and interventional radiology.
2014 Oct; 37(5):1220-5. doi:
10.1007/s00270-013-0780-2. [PMID: 24232038] - Muhammad Sohaib, Anjum Afshan, Shabana Saeed, Mujahid Ali Khalid, Mohammad Yousuf. Formulation and evaluation of a single vial lyophilized preparation of technetium-99m labeled ethylene dicysteine as a renal scintigraphic agent.
Pakistan journal of pharmaceutical sciences.
2014 Sep; 27(5):1287-94. doi:
NULL. [PMID: 25176364] - Brian Pogatchnik, Serena Monti, David H Lewis, Demetra A Heinrich, Lorenzo Mannelli. Intraperitoneal urine leak after prostatectomy confirmed by 99mTc-MAG3 renogram.
Clinical nuclear medicine.
2014 Aug; 39(8):744-6. doi:
10.1097/rlu.0000000000000442. [PMID: 24873796] - Imran Khan Jalbani, Syed Raziuddin Biyabani. Late presentation of posterior urethral valves.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.
2014 May; 24 Suppl 2(?):S155-6. doi:
05.2014/jcpsp.s155s156. [PMID: 24906275] - Seham Mustafa, Abdulhakeem Alsughayer, Abdelhamid Elgazzar, Abdelzaher Elassar, Fakhria Al Sagheer. Effect of sulfa drugs on kidney function and renal scintigraphy.
Nephrology (Carlton, Vic.).
2014 Apr; 19(4):210-6. doi:
10.1111/nep.12200. [PMID: 24387277] - Konstantin Krepkin, Eugene Won, Krishna Ramaswamy, Michael Triolo, Michael Stiffelma, Henry Rusinek, Hersh Chandarana. Dynamic contrast-enhanced MR renography for renal function evaluation in ureteropelvic junction obstruction: feasibility study.
AJR. American journal of roentgenology.
2014 Apr; 202(4):778-83. doi:
10.2214/ajr.13.11321. [PMID: 24660706] - Florian Wimpissinger, Christopher Springer, Amir Kurtaran, Walter Stackl, Christian Türk. Functional aspects of silent ureteral stones investigated with MAG-3 renal scintigraphy.
BMC urology.
2014 Jan; 14(?):3. doi:
10.1186/1471-2490-14-3. [PMID: 24397735] - Ahmed M Harraz, Diaa-Eldin Taha, Ibrahim Shalaby, Ashraf T Hafez. Evaluation of factors predicting recoverability of renal function after pyeloplasty in adults.
Urologia internationalis.
2014; 93(4):403-5. doi:
10.1159/000357625. [PMID: 24923679] - Marcus Weitz, Christoph Licht, Mark Müller, Peter Haber. Renal ultrasound volume in children with primary vesicoureteral reflux allows functional assessment.
Journal of pediatric urology.
2013 Dec; 9(6 Pt B):1077-83. doi:
10.1016/j.jpurol.2013.03.007. [PMID: 23639632] - L Harper, D Bourquard, C Grosos, O Abbo, C Ferdynus, J L Michel, O Dunand, F Sauvat. Cortical transit time as a predictive marker of the need for surgery in children with pelvi-ureteric junction stenosis: preliminary study.
Journal of pediatric urology.
2013 Dec; 9(6 Pt B):1054-8. doi:
10.1016/j.jpurol.2013.03.002. [PMID: 23602207] - William C Klingensmith. 99mTc-mercaptoacetyltriglycine camera-based measurement of renal clearance: should the result be normalized for body surface area?.
Journal of nuclear medicine technology.
2013 Dec; 41(4):279-82. doi:
10.2967/jnmt.113.128124. [PMID: 24167023] - Michael J Keir, Heather J Lambert, Malcolm G Coulthard. Maximizing the sensitivity of the indirect radionuclide cystogram: a retrospective audit.
Pediatric nephrology (Berlin, Germany).
2013 Nov; 28(11):2137-41. doi:
10.1007/s00467-013-2528-2. [PMID: 23771301] - Muhammad Sohaib, Asif Rafique, Shabana Saeed, Anjum Afshan. A comparison of single plasma sample methods to estimate renal clearance using 99mTc-ethylenedicysteine and 99mTc-mercaptoacetyltriglycine.
Clinical physiology and functional imaging.
2013 Sep; 33(5):353-8. doi:
10.1111/cpf.12034. [PMID: 23701132] - Marion Scharpfenecker, Ben Floot, Nicola S Russell, Rob P Coppes, Fiona A Stewart. Endoglin haploinsufficiency attenuates radiation-induced deterioration of kidney function in mice.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2013 Sep; 108(3):464-8. doi:
10.1016/j.radonc.2013.06.016. [PMID: 23849167] - Marianne Tondeur, Cécile Nogarède, Gilda Donoso, Amy Piepsz. Inter- and intra-observer reproducibility of quantitative renographic parameters of differential function and renal drainage in children.
Scandinavian journal of clinical and laboratory investigation.
2013 Aug; 73(5):414-21. doi:
10.3109/00365513.2013.797597. [PMID: 23819645] - Yiyan Liu. FDG PET/CT and renal scan demonstrations of carcinoma in the urinary bladder and bladder diverticulum.
Clinical nuclear medicine.
2013 Jul; 38(7):580-1. doi:
10.1097/rlu.0b013e318286c03e. [PMID: 23478848] - Noriko Takahara, Tsuneo Saga, Masayuki Inubushi, Hiroyuki Kusuhara, Chie Seki, Sumito Ito, Nobuyuki Oyama, Osamu Yokoyama, Yuichi Sugiyama, Yasuhisa Fujibayashi. Drugs interacting with organic anion transporter-1 affect uptake of Tc-99m-mercaptoacetyl-triglycine (MAG3) in the human kidney: therapeutic drug interaction in Tc-99m-MAG3 diagnosis of renal function and possible application of Tc-99m-MAG3 for drug development.
Nuclear medicine and biology.
2013 Jul; 40(5):643-50. doi:
10.1016/j.nucmedbio.2013.03.006. [PMID: 23618840] - Parsia A Vagefi, Jesse J Qian, David M Carlson, Carina Mari Aparici, Ryutaro Hirose, Flavio Vincenti, David Wojciechowski. Native renal function after combined liver-kidney transplant for type 1 hepatorenal syndrome: initial report on the use of postoperative Technetium-99 m-mercaptoacetyltriglycine scans.
Transplant international : official journal of the European Society for Organ Transplantation.
2013 May; 26(5):471-6. doi:
10.1111/tri.12066. [PMID: 23384317] - Seham Mustafa, Abdelhamid H Elgazzar. Effect of the NSAID diclofenac on 99mTc-MAG3 and 99mTc-DTPA renography.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2013 May; 54(5):801-6. doi:
10.2967/jnumed.112.109595. [PMID: 23528384] - Ui-Jun Park, Hyoung-Tae Kim, Won-Hyun Cho, Min-Young Kim, Eun-Ah Hwang, Seung-Yeup Han, Sung-Bae Park, Hyun-Chul Kim, Seok-Kil Zeon. Use of early postoperative MAG3 renal scan to predict long-term outcomes of renal transplants.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2013 Apr; 11(2):118-21. doi:
10.6002/ect.2012.0090. [PMID: 23477352] - Kodai Nishi, Masato Kobayashi, Ryuichi Nishii, Naoto Shikano, Norito Takamura, Noriyuki Kuga, Keishi Yamasaki, Shigeki Nagamachi, Shozo Tamura, Masaki Otagiri, Keiichi Kawai. Pharmacokinetic alteration of (99m)Tc-MAG3 using serum protein binding displacement method.
Nuclear medicine and biology.
2013 Apr; 40(3):366-70. doi:
10.1016/j.nucmedbio.2012.12.002. [PMID: 23312701] - Kathrin Weyer, Rikke Nielsen, Steen V Petersen, Erik I Christensen, Michael Rehling, Henrik Birn. Renal uptake of 99mTc-dimercaptosuccinic acid is dependent on normal proximal tubule receptor-mediated endocytosis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2013 Jan; 54(1):159-65. doi:
10.2967/jnumed.112.110528. [PMID: 23232279] - Andrew T Taylor, Neeta Shenvi, Russell D Folks, Ernest V Garcia, Bital Savir Baruch, Amita Manatunga. Reference values for renal size obtained from MAG3 scintigraphy.
Clinical nuclear medicine.
2013 Jan; 38(1):13-7. doi:
10.1097/rlu.0b013e318270866f. [PMID: 23235485] - Hidenori Kanazawa, Atsushi Kotoda, Tetsu Akimoto, Takeshi Shinozaki, Makoto Inoue, Hideharu Sugimoto, Eiji Kusano. Serial Tc-99m MAG3 renography evaluating the recovery of acute kidney injury associated with minimal change nephrotic syndrome.
Internal medicine (Tokyo, Japan).
2013; 52(9):987-91. doi:
10.2169/internalmedicine.52.9204. [PMID: 23648719] - Murat Sadic, Koray Demirel, Gökhan Koca, Hasan Ikbal Atilgan, Meliha Korkmaz. An incidental detection of aortic aneurysm on Tc-99m MAG3 renal scintigraphy.
Nuclear medicine review. Central & Eastern Europe.
2013; 16(2):97-9. doi:
10.5603/nmr.2013.0044. [PMID: 24068642] - Mohammed N Tantawy, Rosie Jiang, Feng Wang, Keiko Takahashi, Todd E Peterson, Dana Zemel, Chuan-Ming Hao, Hiroki Fujita, Raymond C Harris, Christopher C Quarles, Takamune Takahashi. Assessment of renal function in mice with unilateral ureteral obstruction using 99mTc-MAG3 dynamic scintigraphy.
BMC nephrology.
2012 Dec; 13(?):168. doi:
10.1186/1471-2369-13-168. [PMID: 23228112] - Siamak Sabour, Fariba Ghassemi. The reproducibility of measurements of differential renal function in paediatric 99mTc-MAG3 renography: is this correct?.
Nuclear medicine communications.
2012 Dec; 33(12):1311; author reply 1311-2. doi:
10.1097/mnm.0b013e328359453a. [PMID: 22972373] - Katsunori Tatsugami, Shingo Tanaka, Satoshi Ohtsubo, Junichi Inokuchi, Akira Yokomizo, Kentaro Kuroiwa, Yoo Hyun Song, Seiji Naito. Causes of diminished renal function in the affected kidney after partial nephrectomy.
BJU international.
2012 Oct; 110(8 Pt B):E357-61. doi:
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European journal of nuclear medicine and molecular imaging.
2012 Sep; 39(9):1483-91. doi:
10.1007/s00259-012-2151-7. [PMID: 22644714] - Veysel Akgun, Bilal Battal, Murat Kocaoglu, Emrah Ozcan, Sinan Akay, Seyfettin Ilgan. Sonographic measurement of diuretic-induced renal length changes: are they correlated with renal function?.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.
2012 Sep; 31(9):1351-6. doi:
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Nuclear medicine communications.
2012 Aug; 33(8):824-31. doi:
10.1097/mnm.0b013e32835587da. [PMID: 22692584] - Francesco Porpiglia, Cristian Fiori, Riccardo Bertolo, Ivano Morra, Roberto Russo, Giorgina Piccoli, Tiziana Angusti, Valerio Podio. Long-term functional evaluation of the treated kidney in a prospective series of patients who underwent laparoscopic partial nephrectomy for small renal tumors.
European urology.
2012 Jul; 62(1):130-5. doi:
10.1016/j.eururo.2012.02.001. [PMID: 22349568] - Alex K Wu, Thanh C Tran, Mathew D Sorensen, Jeremy C Durack, Marshall L Stoller. Relative renal function does not improve after relieving chronic renal obstruction.
BJU international.
2012 May; 109(10):1540-4. doi:
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Revista espanola de medicina nuclear e imagen molecular.
2012 May; 31(3):155-7. doi:
10.1016/j.remn.2011.11.013. [PMID: 23236626] - Jessica R Leschied, Ka Kit Wong, Milton D Gross. 99mTc MAG3 renography demonstrating return to normal renal function following resolution of renal vein thrombosis.
Clinical nuclear medicine.
2012 Apr; 37(4):382-4. doi:
10.1097/rlu.0b013e318239249f. [PMID: 22391712] - Francesco Porpiglia, Cristian Fiori, Riccardo Bertolo, Tiziana Angusti, Giorgina B Piccoli, Valerio Podio, Roberto Russo. The effects of warm ischaemia time on renal function after laparoscopic partial nephrectomy in patients with normal contralateral kidney.
World journal of urology.
2012 Apr; 30(2):257-63. doi:
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