Perfluorocapric acid (BioDeep_00000018067)

 

Secondary id: BioDeep_00000397756

human metabolite


代谢物信息卡片


Perfluorodecanoic acid

化学式: C10HF19O2 (513.9673154)
中文名称: 十九氟癸酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(=O)(C(C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O
InChI: InChI=1S/C10HF19O2/c11-2(12,1(30)31)3(13,14)4(15,16)5(17,18)6(19,20)7(21,22)8(23,24)9(25,26)10(27,28)29/h(H,30,31)

描述信息

同义名列表

2 个代谢物同义名

Perfluorodecanoic acid; Perfluorocapric acid



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Vladimíra Puklová, Naděžda Čapková, Alena Fialová, Adam Vavrouš, Kristýna Žejglicová, Milena Černá. Association among serum per- and polyfluoroalkyl substances, lipid profile and metabolic syndrome in Czech adults, HBM-EHES survey 2019. Central European journal of public health. 2023 Dec; 31(4):227-234. doi: 10.21101/cejph.a7799. [PMID: 38309699]
  • Hong Xu, Xu Zhong, Taotao Wang, Shanshan Wu, Huanan Guan, Dongxu Wang. (-)-Epigallocatechin-3-Gallate Reduces Perfluorodecanoic Acid-Exacerbated Adiposity and Hepatic Lipid Accumulation in High-Fat Diet-Fed Male C57BL/6J Mice. Molecules (Basel, Switzerland). 2023 Nov; 28(23):. doi: 10.3390/molecules28237832. [PMID: 38067561]
  • Taotao Wang, Hong Xu, Yu Guo, Yuanxin Guo, Huanan Guan, Dongxu Wang. Perfluorodecanoic acid promotes high-fat diet-triggered adiposity and hepatic lipid accumulation by modulating the NLRP3/caspase-1 pathway in male C57BL/6J mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Aug; 178(?):113943. doi: 10.1016/j.fct.2023.113943. [PMID: 37451596]
  • Taotao Wang, Hong Xu, Yu Guo, Zhanming Li, Hua Ye, Liang Wu, Yuanxin Guo, Dongxu Wang. Perfluorodecanoic acid promotes adipogenesis via NLRP3 inflammasome-mediated pathway in HepG2 and 3T3-L1 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Jan; 171(?):113520. doi: 10.1016/j.fct.2022.113520. [PMID: 36423729]
  • Emily Marques, Marisa Pfohl, Wei Wei, Giuseppe Tarantola, Lucie Ford, Ogochukwu Amaeze, Jessica Alesio, Sangwoo Ryu, Xuelian Jia, Hao Zhu, Geoffrey D Bothun, Angela Slitt. Replacement per- and polyfluoroalkyl substances (PFAS) are potent modulators of lipogenic and drug metabolizing gene expression signatures in primary human hepatocytes. Toxicology and applied pharmacology. 2022 05; 442(?):115991. doi: 10.1016/j.taap.2022.115991. [PMID: 35337807]
  • Roger Drew, Tarah G Hagen, David Champness, Amelie Sellier. Half-lives of several polyfluoroalkyl substances (PFAS) in cattle serum and tissues. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2022 Feb; 39(2):320-340. doi: 10.1080/19440049.2021.1991004. [PMID: 34732107]
  • Louise Dalsager, Tina Kold Jensen, Flemming Nielsen, Philippe Grandjean, Niels Bilenberg, Helle Raun Andersen. No association between maternal and child PFAS concentrations and repeated measures of ADHD symptoms at age 2½ and 5 years in children from the Odense Child Cohort. Neurotoxicology and teratology. 2021 Nov; 88(?):107031. doi: 10.1016/j.ntt.2021.107031. [PMID: 34563660]
  • Xu Han, Lingling Meng, Gaoxin Zhang, Yingming Li, Yali Shi, Qinghua Zhang, Guibin Jiang. Exposure to novel and legacy per- and polyfluoroalkyl substances (PFASs) and associations with type 2 diabetes: A case-control study in East China. Environment international. 2021 11; 156(?):106637. doi: 10.1016/j.envint.2021.106637. [PMID: 33993001]
  • Paige A Bommarito, Kelly K Ferguson, John D Meeker, Thomas F McElrath, David E Cantonwine. Maternal Levels of Perfluoroalkyl Substances (PFAS) during Early Pregnancy in Relation to Preeclampsia Subtypes and Biomarkers of Preeclampsia Risk. Environmental health perspectives. 2021 10; 129(10):107004. doi: 10.1289/ehp9091. [PMID: 34637358]
  • Randi Grønnestad, Silje Modahl Johanson, Mette H B Müller, Daniel Schlenk, Philip Tanabe, Åse Krøkje, Veerle L B Jaspers, Bjørn Munro Jenssen, Erik M Ræder, Jan L Lyche, Qingyang Shi, Augustine Arukwe. Effects of an environmentally relevant PFAS mixture on dopamine and steroid hormone levels in exposed mice. Toxicology and applied pharmacology. 2021 10; 428(?):115670. doi: 10.1016/j.taap.2021.115670. [PMID: 34371090]
  • Yanqiu Ou, Xiaowen Zeng, Shao Lin, Michael S Bloom, Fengzhen Han, Xiaohua Xiao, Hui Wang, Rosemary Matala, Xiaohong Li, Yanji Qu, Zhiqiang Nie, Guanghui Dong, Xiaoqing Liu. Gestational exposure to perfluoroalkyl substances and congenital heart defects: A nested case-control pilot study. Environment international. 2021 09; 154(?):106567. doi: 10.1016/j.envint.2021.106567. [PMID: 33882431]
  • Jonathan Vibe Retbøll Christensen, Khushal Khan Bangash, Pál Weihe, Phillippe Grandjean, Flemming Nielsen, Tina Kold Jensen, Maria Skaalum Petersen. Maternal exposure to perfluoroalkyl chemicals and anogenital distance in the offspring: A Faroese cohort study. Reproductive toxicology (Elmsford, N.Y.). 2021 09; 104(?):52-57. doi: 10.1016/j.reprotox.2021.06.016. [PMID: 34182087]
  • Jaclyn A Janis, Sheryl L Rifas-Shiman, Shravanthi M Seshasayee, Sharon Sagiv, Antonia M Calafat, Diane R Gold, Brent A Coull, Clifford J Rosen, Emily Oken, Abby F Fleisch. Plasma Concentrations of Per- and Polyfluoroalkyl Substances and Body Composition From Mid-Childhood to Early Adolescence. The Journal of clinical endocrinology and metabolism. 2021 08; 106(9):e3760-e3770. doi: 10.1210/clinem/dgab187. [PMID: 33740056]
  • Damaskini Valvi, Kurt Højlund, Brent A Coull, Flemming Nielsen, Pal Weihe, Philippe Grandjean. Life-course Exposure to Perfluoroalkyl Substances in Relation to Markers of Glucose Homeostasis in Early Adulthood. The Journal of clinical endocrinology and metabolism. 2021 07; 106(8):2495-2504. doi: 10.1210/clinem/dgab267. [PMID: 33890111]
  • Cheng Zou, Haoni Yan, Zina Wen, Changchang Li, Song Zhang, Yingfen Ying, Peipei Pan, Yang Li, Huitao Li, Xiaoheng Li, Yiyan Wang, Ying Zhong, Ren-Shan Ge, Dapang Rao. Perfluorotridecanoic Acid Inhibits Leydig Cell Maturation in Male Rats in Late Puberty via Changing Testicular Lipid Component. Chemical research in toxicology. 2021 06; 34(6):1542-1555. doi: 10.1021/acs.chemrestox.0c00458. [PMID: 34081457]
  • Julia R Varshavsky, Joshua F Robinson, Yan Zhou, Kenisha A Puckett, Elaine Kwan, Sirirak Buarpung, Rayyan Aburajab, Stephanie L Gaw, Saunak Sen, Songmei Gao, Sabrina Crispo Smith, June-Soo Park, Igor Zakharevich, Roy R Gerona, Susan J Fisher, Tracey J Woodruff. Organophosphate Flame Retardants, Highly Fluorinated Chemicals, and Biomarkers of Placental Development and Disease During Mid-Gestation. Toxicological sciences : an official journal of the Society of Toxicology. 2021 05; 181(2):215-228. doi: 10.1093/toxsci/kfab028. [PMID: 33677611]
  • Ram B Jain. Perfluoroalkyl acids and their isomers, diabetes, anemia, and albuminuria: Variabilities with deteriorating kidney function. Ecotoxicology and environmental safety. 2021 Jan; 208(?):111625. doi: 10.1016/j.ecoenv.2020.111625. [PMID: 33396145]
  • S Salihovic, L Lind, A Larsson, P M Lind. Plasma perfluoroalkyls are associated with decreased levels of proteomic inflammatory markers in a cross-sectional study of an elderly population. Environment international. 2020 12; 145(?):106099. doi: 10.1016/j.envint.2020.106099. [PMID: 32916415]
  • Hwa Young Kim, Kyoung-Nam Kim, Choong Ho Shin, Youn-Hee Lim, Johanna Inhyang Kim, Bung-Nyun Kim, Yun-Chul Hong, Young Ah Lee. The Relationship Between Perfluoroalkyl Substances Concentrations and Thyroid Function in Early Childhood: A Prospective Cohort Study. Thyroid : official journal of the American Thyroid Association. 2020 11; 30(11):1556-1565. doi: 10.1089/thy.2019.0436. [PMID: 32368952]
  • Franco Scinicariello, Melanie C Buser, Lina Balluz, Kimberly Gehle, H Edward Murray, Henry G Abadin, Roberta Attanasio. Perfluoroalkyl acids, hyperuricemia and gout in adults: Analyses of NHANES 2009-2014. Chemosphere. 2020 Nov; 259(?):127446. doi: 10.1016/j.chemosphere.2020.127446. [PMID: 32590180]
  • Yu Ait Bamai, Houman Goudarzi, Atsuko Araki, Emiko Okada, Ikuko Kashino, Chihiro Miyashita, Reiko Kishi. Effect of prenatal exposure to per- and polyfluoroalkyl substances on childhood allergies and common infectious diseases in children up to age 7 years: The Hokkaido study on environment and children's health. Environment international. 2020 10; 143(?):105979. doi: 10.1016/j.envint.2020.105979. [PMID: 32717646]
  • Meng-Shan Tsai, Shu-Han Chang, Wen-Hung Kuo, Ching-Hua Kuo, Szu-Yi Li, Ming-Yang Wang, Dwan-Ying Chang, Yen-Shen Lu, Chiun-Sheng Huang, Ann-Lii Cheng, Ching-Hung Lin, Pau-Chung Chen. A case-control study of perfluoroalkyl substances and the risk of breast cancer in Taiwanese women. Environment international. 2020 09; 142(?):105850. doi: 10.1016/j.envint.2020.105850. [PMID: 32580117]
  • Marion Ouidir, Pauline Mendola, Germaine M Buck Louis, Kurunthachalam Kannan, Cuilin Zhang, Fasil Tekola-Ayele. Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation. Clinical epigenetics. 2020 07; 12(1):103. doi: 10.1186/s13148-020-00894-6. [PMID: 32653021]
  • Sichen Gao, Mingyang Jing, Mengchen Xu, Dengcheng Han, Qigui Niu, Rutao Liu. Cytotoxicity of perfluorodecanoic acid on mouse primary nephrocytes through oxidative stress: Combined analysis at cellular and molecular levels. Journal of hazardous materials. 2020 07; 393(?):122444. doi: 10.1016/j.jhazmat.2020.122444. [PMID: 32169814]
  • Richard Christian Jensen, Marianne S Andersen, Pia Veldt Larsen, Dorte Glintborg, Christine Dalgård, Clara Amalie Gade Timmermann, Flemming Nielsen, Maria Boysen Sandberg, Helle Raun Andersen, Henrik Thybo Christesen, Philippe Grandjean, Tina Kold Jensen. Prenatal Exposures to Perfluoroalkyl Acids and Associations with Markers of Adiposity and Plasma Lipids in Infancy: An Odense Child Cohort Study. Environmental health perspectives. 2020 07; 128(7):77001. doi: 10.1289/ehp5184. [PMID: 32628516]
  • Anika L Dzierlenga, Veronica G Robinson, Suramya Waidyanatha, Michael J DeVito, Max A Eifrid, Seth T Gibbs, Courtney A Granville, Chad R Blystone. Toxicokinetics of perfluorohexanoic acid (PFHxA), perfluorooctanoic acid (PFOA) and perfluorodecanoic acid (PFDA) in male and female Hsd:Sprague dawley SD rats following intravenous or gavage administration. Xenobiotica; the fate of foreign compounds in biological systems. 2020 Jun; 50(6):722-732. doi: 10.1080/00498254.2019.1683776. [PMID: 31680603]
  • Sverre Wikström, Ping-I Lin, Christian H Lindh, Huan Shu, Carl-Gustaf Bornehag. Maternal serum levels of perfluoroalkyl substances in early pregnancy and offspring birth weight. Pediatric research. 2020 05; 87(6):1093-1099. doi: 10.1038/s41390-019-0720-1. [PMID: 31835271]
  • Richard Christian Jensen, Dorte Glintborg, Clara Amalie Gade Timmermann, Flemming Nielsen, Henriette Boye Kyhl, Hanne Frederiksen, Anna-Maria Andersson, Anders Juul, Johannes J Sidelmann, Helle Raun Andersen, Philippe Grandjean, Marianne S Andersen, Tina Kold Jensen. Prenatal exposure to perfluorodecanoic acid is associated with lower circulating concentration of adrenal steroid metabolites during mini puberty in human female infants. The Odense Child Cohort. Environmental research. 2020 03; 182(?):109101. doi: 10.1016/j.envres.2019.109101. [PMID: 32069767]
  • Gang Liu, Bo Zhang, Yang Hu, Jennifer Rood, Liming Liang, Lu Qi, George A Bray, Lilian DeJonge, Brent Coull, Philippe Grandjean, Jeremy D Furtado, Qi Sun. Associations of Perfluoroalkyl substances with blood lipids and Apolipoproteins in lipoprotein subspecies: the POUNDS-lost study. Environmental health : a global access science source. 2020 01; 19(1):5. doi: 10.1186/s12940-020-0561-8. [PMID: 31931806]
  • Mohd Redzuan Ramli, Minoru Yoneda, Mustafa Ali Mohd, Didi Erwandi Mohamad Haron, Emmy Dayana Ahmad. Level and determinants of serum perfluoroalkyl acids (PFAAs) in a population in Klang Valley, Malaysia. International journal of hygiene and environmental health. 2020 01; 223(1):179-186. doi: 10.1016/j.ijheh.2019.09.005. [PMID: 31542349]
  • Dongxu Wang, Qiang Gao, Taotao Wang, Zhipeng Kan, Xin Li, Lizhen Hu, Chuan-Yi Peng, Frank Qian, Yijun Wang, Daniel Granato. Green tea polyphenols and epigallocatechin-3-gallate protect against perfluorodecanoic acid induced liver damage and inflammation in mice by inhibiting NLRP3 inflammasome activation. Food research international (Ottawa, Ont.). 2020 01; 127(?):108628. doi: 10.1016/j.foodres.2019.108628. [PMID: 31882076]
  • Colleen Shelly, Philippe Grandjean, Youssef Oulhote, Peter Plomgaard, Ruth Frikke-Schmidt, Flemming Nielsen, Denis Zmirou-Navier, Pal Weihe, Damaskini Valvi. Early Life Exposures to Perfluoroalkyl Substances in Relation to Adipokine Hormone Levels at Birth and During Childhood. The Journal of clinical endocrinology and metabolism. 2019 11; 104(11):5338-5348. doi: 10.1210/jc.2019-00385. [PMID: 31216000]
  • Eriko Yamazaki, Sachi Taniyasu, Kosuke Noborio, Heesoo Eun, Pooja Thaker, Nirmal J I Kumar, Xinhong Wang, Nobuyoshi Yamashita. Accumulation of perfluoroalkyl substances in lysimeter-grown rice in Japan using tap water and simulated contaminated water. Chemosphere. 2019 Sep; 231(?):502-509. doi: 10.1016/j.chemosphere.2019.05.022. [PMID: 31151010]
  • Rachel Cluett, Shravanthi M Seshasayee, Lisa B Rokoff, Sheryl L Rifas-Shiman, Xiaoyun Ye, Antonia M Calafat, Diane R Gold, Brent Coull, Catherine M Gordon, Clifford J Rosen, Emily Oken, Sharon K Sagiv, Abby F Fleisch. Per- and Polyfluoroalkyl Substance Plasma Concentrations and Bone Mineral Density in Midchildhood: A Cross-Sectional Study (Project Viva, United States). Environmental health perspectives. 2019 08; 127(8):87006. doi: 10.1289/ehp4918. [PMID: 31433236]
  • Youping Tian, Hong Liang, Maohua Miao, Fen Yang, Honglei Ji, Wencheng Cao, Xiaofang Liu, Xiaotian Zhang, Aimin Chen, Hong Xiao, Hui Hu, Wei Yuan. Maternal plasma concentrations of perfluoroalkyl and polyfluoroalkyl substances during pregnancy and anogenital distance in male infants. Human reproduction (Oxford, England). 2019 07; 34(7):1356-1368. doi: 10.1093/humrep/dez058. [PMID: 31242507]
  • Aina Jansen, Mette H B Müller, Randi Grønnestad, Ole Klungsøyr, Anuschka Polder, Eystein Skjerve, Jan Aaseth, Jan L Lyche. Decreased plasma levels of perfluoroalkylated substances one year after bariatric surgery. The Science of the total environment. 2019 Mar; 657(?):863-870. doi: 10.1016/j.scitotenv.2018.11.453. [PMID: 30677951]
  • Sook-Jin Kim, Eun-Jeong Choi, Go-Wun Choi, Yong-Bok Lee, Hea-Young Cho. Exploring sex differences in human health risk assessment for PFNA and PFDA using a PBPK model. Archives of toxicology. 2019 02; 93(2):311-330. doi: 10.1007/s00204-018-2365-y. [PMID: 30483840]
  • Sung-Hee Seo, Min-Hui Son, Sung-Deuk Choi, Duk-Hee Lee, Yoon-Seok Chang. Influence of exposure to perfluoroalkyl substances (PFASs) on the Korean general population: 10-year trend and health effects. Environment international. 2018 04; 113(?):149-161. doi: 10.1016/j.envint.2018.01.025. [PMID: 29425899]
  • Qi Sun, Geng Zong, Damaskini Valvi, Flemming Nielsen, Brent Coull, Philippe Grandjean. Plasma Concentrations of Perfluoroalkyl Substances and Risk of Type 2 Diabetes: A Prospective Investigation among U.S. Women. Environmental health perspectives. 2018 03; 126(3):037001. doi: 10.1289/ehp2619. [PMID: 29498927]
  • Ana M Mora, Abby F Fleisch, Sheryl L Rifas-Shiman, Jennifer A Woo Baidal, Larissa Pardo, Thomas F Webster, Antonia M Calafat, Xiaoyun Ye, Emily Oken, Sharon K Sagiv. Early life exposure to per- and polyfluoroalkyl substances and mid-childhood lipid and alanine aminotransferase levels. Environment international. 2018 02; 111(?):1-13. doi: 10.1016/j.envint.2017.11.008. [PMID: 29156323]
  • Jun-Kyoung Lee, Sang-Hyun Kim. Correlation between mast cell-mediated allergic inflammation and length of perfluorinated compounds. Journal of toxicology and environmental health. Part A. 2018; 81(9):302-313. doi: 10.1080/15287394.2018.1440188. [PMID: 29482476]
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