M1G-dR (BioDeep_00000180617)
human metabolite blood metabolite
代谢物信息卡片
化学式: C13H13N5O4 (303.09674980000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(C(OC1N2C=NC3=C2N=C4N=CC=CN4C3=O)CO)O
InChI: InChI=1S/C13H13N5O4/c19-5-8-7(20)4-9(22-8)18-6-15-10-11(18)16-13-14-2-1-3-17(13)12(10)21/h1-3,6-9,19-20H,4-5H2
描述信息
同义名列表
7 个代谢物同义名
3-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H,10H-pyrimido[1,2-a]purin-10-one; 3-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimido[1,2-a]purin-10-one; 3-(2-Deoxyribofuranosyl)pyrimido(1,2-a)purin-10(3H)-one; Malondialdehyde-2-deoxyguanosine adduct; m(1)g-Deoxyribose; m1g-Deoxyribose; M1G-dR
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yo-Chan Jeong, James A Swenberg. Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals.
Free radical biology & medicine.
2005 Oct; 39(8):1021-9. doi:
10.1016/j.freeradbiomed.2005.05.018. [PMID: 16198229] - Chi-Chen Hong, Bing-Kou Tang, Venketeshwer Rao, Sanjiv Agarwal, Lisa Martin, David Tritchler, Martin Yaffe, Norman F Boyd. Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional study.
Breast cancer research : BCR.
2004; 6(4):R338-51. doi:
10.1186/bcr797. [PMID: 15217501] - Anne-Mette Hoberg, Michael Otteneder, Lawrence J Marnett, Henrik E Poulsen. Measurement of the malondialdehyde-2'-deoxyguanosine adduct in human urine by immuno-extraction and liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry.
Journal of mass spectrometry : JMS.
2004 Jan; 39(1):38-42. doi:
10.1002/jms.547. [PMID: 14760611] - Chiara Leuratti, Mark A Watson, Eliot J Deag, Ailsa Welch, Rajinder Singh, Elke Gottschalg, Lawrence J Marnett, Wendy Atkin, Nicholas E Day, David E G Shuker, Sheila A Bingham. Detection of malondialdehyde DNA adducts in human colorectal mucosa: relationship with diet and the presence of adenomas.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2002 Mar; 11(3):267-73. doi:
". [PMID: 11895876] - Michael Otteneder, John P Plastaras, Lawrence J Marnett. Reaction of malondialdehyde-DNA adducts with hydrazines-development of a facile assay for quantification of malondialdehyde equivalents in DNA.
Chemical research in toxicology.
2002 Mar; 15(3):312-8. doi:
10.1021/tx010105v. [PMID: 11896677] - S M Everett, R Singh, C Leuratti, K L White, P Neville, D Greenwood, L J Marnett, C J Schorah, D Forman, D Shuker, A T Axon. Levels of malondialdehyde-deoxyguanosine in the gastric mucosa: relationship with lipid peroxidation, ascorbic acid, and Helicobacter pylori.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2001 Apr; 10(4):369-76. doi:
". [PMID: 11319178] - N C Schnetz-Boutaud, S Saleh, L J Marnett, M P Stone. Structure of the malondialdehyde deoxyguanosine adduct M1G when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene.
Advances in experimental medicine and biology.
2001; 500(?):513-6. doi:
10.1007/978-1-4615-0667-6_77. [PMID: 11764989] - C Leuratti, R Singh, E J Deag, E Griech, R Hughes, S A Bingham, J P Plastaras, L J Marnett, D E Shuker. A sensitive immunoslot-blot assay for detection of malondialdehyde-deoxyguanosine in human DNA.
IARC scientific publications.
1999; ?(150):197-203. doi:
". [PMID: 10626221] - C L Sevilla, N H Mahle, N Eliezer, A Uzieblo, S M O'Hara, M Nokubo, R Miller, C A Rouzer, L J Marnett. Development of monoclonal antibodies to the malondialdehyde-deoxyguanosine adduct, pyrimidopurinone.
Chemical research in toxicology.
1997 Feb; 10(2):172-80. doi:
10.1021/tx960120d. [PMID: 9049428] - A K Chaudhary, M Nokubo, G R Reddy, S N Yeola, J D Morrow, I A Blair, L J Marnett. Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver.
Science (New York, N.Y.).
1994 Sep; 265(5178):1580-2. doi:
10.1126/science.8079172. [PMID: 8079172] - A K Chaudhary, M Nokubo, L J Marnett, I A Blair. Analysis of the malondialdehyde-2'-deoxyguanosine adduct in rat liver DNA by gas chromatography/electron capture negative chemical ionization mass spectrometry.
Biological mass spectrometry.
1994 Aug; 23(8):457-64. doi:
10.1002/bms.1200230802. [PMID: 7918689]