m-Hydroxyephedrine (BioDeep_00000180610)
human metabolite blood metabolite
代谢物信息卡片
HCL(R-(R*,s*))-isomer OF 3-hydroxyephedrine
化学式: C10H15NO2 (181.110273)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C(C1=CC(=CC=C1)O)O)NC
InChI: InChI=1S/C10H15NO2/c1-7(11-2)10(13)8-4-3-5-9(12)6-8/h3-7,10-13H,1-2H3
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yusuke Tokuda, Mamoru Sakakibara, Keiichiro Yoshinaga, Shiro Yamada, Kiwamu Kamiya, Naoya Asakawa, Takashi Yoshitani, Keiji Noguchi, Osamu Manabe, Nagara Tamaki, Hiroyuki Tsutsui. Early therapeutic effects of adaptive servo-ventilation on cardiac sympathetic nervous function in patients with heart failure evaluated using a combination of 11C-HED PET and 123I-MIBG SPECT.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
2019 08; 26(4):1079-1089. doi:
10.1007/s12350-017-1132-4. [PMID: 29181786] - Márcio Galindo Kiuchi, Janis Marc Nolde, Humberto Villacorta, Revathy Carnagarin, Justine Joy Su-Yin Chan, Leslie Marisol Lugo-Gavidia, Jan K Ho, Vance B Matthews, Girish Dwivedi, Markus P Schlaich. New Approaches in the Management of Sudden Cardiac Death in Patients with Heart Failure-Targeting the Sympathetic Nervous System.
International journal of molecular sciences.
2019 May; 20(10):. doi:
10.3390/ijms20102430. [PMID: 31100908] - James T Thackeray, Robert A deKemp, Rob S Beanlands, Jean N DaSilva. Early diabetes treatment does not prevent sympathetic dysinnervation in the streptozotocin diabetic rat heart.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
2014 Aug; 21(4):829-41. doi:
10.1007/s12350-014-9900-x. [PMID: 24890379] - James T Thackeray, Robert A deKemp, Rob S Beanlands, Jean N DaSilva. Insulin restores myocardial presynaptic sympathetic neuronal integrity in insulin-resistant diabetic rats.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
2013 Oct; 20(5):845-56. doi:
10.1007/s12350-013-9759-2. [PMID: 23842711] - James T Thackeray, Jennifer M Renaud, Myra Kordos, Ran Klein, Robert A Dekemp, Rob S B Beanlands, Jean N DaSilva. Test-retest repeatability of quantitative cardiac 11C-meta-hydroxyephedrine measurements in rats by small animal positron emission tomography.
Nuclear medicine and biology.
2013 Jul; 40(5):676-81. doi:
10.1016/j.nucmedbio.2013.03.007. [PMID: 23664690] - David M Raffel, Wei Chen, Yong-Woon Jung, Keun Sam Jang, Guie Gu, Nicholas V Cozzi. Radiotracers for cardiac sympathetic innervation: transport kinetics and binding affinities for the human norepinephrine transporter.
Nuclear medicine and biology.
2013 Apr; 40(3):331-7. doi:
10.1016/j.nucmedbio.2012.11.014. [PMID: 23306137] - James T Thackeray, Rob S Beanlands, Jean N Dasilva. Presence of specific 11C-meta-Hydroxyephedrine retention in heart, lung, pancreas, and brown adipose tissue.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2007 Oct; 48(10):1733-40. doi:
10.2967/jnumed.107.043570. [PMID: 17873125] - David M Raffel, Wei Chen, Phillip S Sherman, David L Gildersleeve, Yong-Woon Jung. Dependence of cardiac 11C-meta-hydroxyephedrine retention on norepinephrine transporter density.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2006 Sep; 47(9):1490-6. doi:
NULL. [PMID: 16954558] - Anne Rixt Buursma, Antoine M J Beerens, Erik F J de Vries, Aren van Waarde, Marianne G Rots, Geke A P Hospers, Willem Vaalburg, Hidde J Haisma. The human norepinephrine transporter in combination with 11C-m-hydroxyephedrine as a reporter gene/reporter probe for PET of gene therapy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2005 Dec; 46(12):2068-75. doi:
NULL. [PMID: 16330572] - Rodica Pop-Busui, Ian Kirkwood, Helena Schmid, Victor Marinescu, Justin Schroeder, Dennis Larkin, Elina Yamada, David M Raffel, Martin J Stevens. Sympathetic dysfunction in type 1 diabetes: association with impaired myocardial blood flow reserve and diastolic dysfunction.
Journal of the American College of Cardiology.
2004 Dec; 44(12):2368-74. doi:
10.1016/j.jacc.2004.09.033. [PMID: 15607400] - A L Malizia, J K Melichar, C G Rhodes, A Haida, A H Reynolds, T Jones, D J Nutt. Desipramine binding to noradrenaline reuptake sites in cardiac sympathetic neurons in man in vivo.
European journal of pharmacology.
2000 Mar; 391(3):263-7. doi:
10.1016/s0014-2999(00)00103-5. [PMID: 10729367] - F Hartmann, S Ziegler, S Nekolla, M Hadamitzky, M Seyfarth, G Richardt, M Schwaiger. Regional patterns of myocardial sympathetic denervation in dilated cardiomyopathy: an analysis using carbon-11 hydroxyephedrine and positron emission tomography.
Heart (British Cardiac Society).
1999 Mar; 81(3):262-70. doi:
10.1136/hrt.81.3.262. [PMID: 10026349] - M P Law, S Osman, R J Davenport, V J Cunningham, V W Pike, P G Camici. Biodistribution and metabolism of [N-methyl-11C]m-hydroxyephedrine in the rat.
Nuclear medicine and biology.
1997 Jul; 24(5):417-24. doi:
10.1016/s0969-8051(97)00007-3. [PMID: 9290077] - J M Link, R E Synovec, K A Krohn, J H Caldwell. High speed liquid chromatography of phenylethanolamines for the kinetic analysis of [11C]-meta-hydroxyephedrine and metabolites in plasma.
Journal of chromatography. B, Biomedical sciences and applications.
1997 May; 693(1):31-41. doi:
10.1016/s0378-4347(97)00040-6. [PMID: 9200516] - T R DeGrado, G D Hutchins, S A Toorongian, D M Wieland, M Schwaiger. Myocardial kinetics of carbon-11-meta-hydroxyephedrine: retention mechanisms and effects of norepinephrine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1993 Aug; 34(8):1287-93. doi:
NULL. [PMID: 8326386] - L Giuliani, G Carmignani, E Belgrano, P Puppo. Transcatheter arterial embolization in urological tumors: the use of isobutyl-2-cyanoacrylate.
The Journal of urology.
1979 May; 121(5):630-4. doi:
10.1016/s0022-5347(17)56913-x. [PMID: 439260] - A C Buck. Disorders of micturition in bacterial prostatitis.
Proceedings of the Royal Society of Medicine.
1975 Aug; 68(8):508-11. doi:
NULL. [PMID: 681]