Isocyanic acid (BioDeep_00000180146)
human metabolite blood metabolite
代谢物信息卡片
Hydrogen isocyanic acid
化学式: CHNO (43.005813599999996)
中文名称: 异氰酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=N)=O
InChI: InChI=1S/CHNO/c2-1-3/h2H
描述信息
同义名列表
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:29202
- PubChem: 6347
- HMDB: HMDB0253627
- Wikipedia: Isocyanic acid
- CAS: 75-13-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Bahadir Simsek, Ufuk Çakatay. Could cyanogenic glycoside rich diet cause increased risk for carbamylation-induced protein damage in individuals with chronic inflammatory diseases?.
Medical hypotheses.
2019 Sep; 130(?):109275. doi:
10.1016/j.mehy.2019.109275. [PMID: 31383327] - C Nicolas, S Jaisson, L Gorisse, F J Tessier, C Niquet-Léridon, P Jacolot, C Pietrement, P Gillery. Carbamylation is a competitor of glycation for protein modification in vivo.
Diabetes & metabolism.
2018 Mar; 44(2):160-167. doi:
10.1016/j.diabet.2017.05.006. [PMID: 28690125] - Anna Pieniążek, Krzysztof Gwoździński. [Carbamylation of proteins--mechanism, causes and consequences].
Postepy higieny i medycyny doswiadczalnej (Online).
2016 May; 70(?):514-21. doi:
10.5604/17322693.1202189. [PMID: 27180968] - Philippe Gillery, Stéphane Jaisson, Laëtitia Gorisse, Christine Pietrement. [Role of protein carbamylation in chronic kidney disease complications].
Nephrologie & therapeutique.
2015 Jun; 11(3):129-34. doi:
10.1016/j.nephro.2014.12.004. [PMID: 25794932] - Monika Praschberger, Marcela Hermann, Christian Laggner, Leopold Jirovetz, Markus Exner, Stylianos Kapiotis, Bernhard M K Gmeiner, Hilde Laggner. Carbamoylation abrogates the antioxidant potential of hydrogen sulfide.
Biochimie.
2013 Nov; 95(11):2069-75. doi:
10.1016/j.biochi.2013.07.018. [PMID: 23896375] - Daniel G Beach, Wojciech Gabryelski. Revisiting the reactivity of uracil during collision induced dissociation: tautomerism and charge-directed processes.
Journal of the American Society for Mass Spectrometry.
2012 May; 23(5):858-68. doi:
10.1007/s13361-012-0343-9. [PMID: 22351291] - Stéphane Jaisson, Christine Pietrement, Philippe Gillery. Carbamylation-derived products: bioactive compounds and potential biomarkers in chronic renal failure and atherosclerosis.
Clinical chemistry.
2011 Nov; 57(11):1499-505. doi:
10.1373/clinchem.2011.163188. [PMID: 21768218] - A Wynckel, C Randoux, H Millart, C Desroches, P Gillery, E Canivet, J Chanard. Kinetics of carbamylated haemoglobin in acute renal failure.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2000 Aug; 15(8):1183-8. doi:
10.1093/ndt/15.8.1183. [PMID: 10910442] - M Dalene, G Skarping, T Brorson. Chromatographic determination of amines in biological fluids with special reference to the biological monitoring of isocyanates and amines. IV. Determination of 1,6-hexamethylenediamine in human urine using capillary gas chromatography and selective ion monitoring.
Journal of chromatography.
1990 Sep; 516(2):405-13. doi:
10.1016/s0021-9673(01)89281-5. [PMID: 2079495] - L C Grammer, K E Harris, J L Malo, A Cartier, R Patterson. The use of an immunoassay index for antibodies against isocyanate human protein conjugates and application to human isocyanate disease.
The Journal of allergy and clinical immunology.
1990 Jul; 86(1):94-8. doi:
10.1016/s0091-6749(05)80128-9. [PMID: 2164544] - A Holmén, B Akesson, L Hansén, J Frithiof, F Mitelman, A Karlsson, L Persson, H Welinder, S Skerfving, B Högstedt. Comparison among five mutagenicity assays in workers producing polyurethane foams.
International archives of occupational and environmental health.
1988; 60(3):175-9. doi:
10.1007/bf00378694. [PMID: 3384483] - P Séguin, A Allard, A Cartier, J L Malo. Prevalence of occupational asthma in spray painters exposed to several types of isocyanates, including polymethylene polyphenylisocyanate.
Journal of occupational medicine. : official publication of the Industrial Medical Association.
1987 Apr; 29(4):340-4. doi:
". [PMID: 3585565] - B T Butcher, M A Reed, C E O'Neil, S Leech, F C Pearson. Immunologic studies of hollow-fiber dialyzer extracts.
Artificial organs.
1984 Aug; 8(3):318-28. doi:
10.1111/j.1525-1594.1984.tb04298.x. [PMID: 6477200] - K E Malten. Dermatological problems with synthetic resins and plastics in glues. Part II.
Dermatosen in Beruf und Umwelt. Occupation and environment.
1984; 32(4):118-25. doi:
". [PMID: 6236964] - E J Bardana, R H Andrach. Occupational asthma secondary to low molecular weight agents used in the plastic and resin industries.
European journal of respiratory diseases.
1983 May; 64(4):241-51. doi:
". [PMID: 6861919] - X Baur. Immunologic cross-reactivity between different albumin-bound isocyanates.
The Journal of allergy and clinical immunology.
1983 Feb; 71(2):197-205. doi:
10.1016/0091-6749(83)90100-8. [PMID: 6296214] - M A Dewair, X Baur. Studies on antigens useful for detection of IgE antibodies in isocyanate-sensitized workers.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie.
1982 Jun; 20(6):337-40. doi:
10.1515/cclm.1982.20.6.337. [PMID: 6288831] - W F Diller, E Herbert. [Lung function and other health parameters in employees of an isocyananide plant (MDI production)].
Zentralblatt fur Arbeitsmedizin, Arbeitsschutz, Prophylaxe und Ergonomie.
1982 Apr; 32(4):128-37. doi:
". [PMID: 7090618]