Iodouracil (BioDeep_00000180067)
human metabolite blood metabolite
代谢物信息卡片
化学式: C4H3IN2O2 (237.9239)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 75%
分子结构信息
SMILES: C1=CN(C(=O)NC1=O)I
InChI: InChI=1S/C4H3IN2O2/c5-7-2-1-3(8)6-4(7)9/h1-2H,(H,6,8,9)
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- E Galanis, R Goldberg, J Reid, P Atherton, J Sloan, H Pitot, J Rubin, A A Adjei, P Burch, S L Safgren, T E Witzig, M M Ames, C Erlichman. Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd).
Annals of oncology : official journal of the European Society for Medical Oncology.
2001 May; 12(5):701-7. doi:
10.1023/a:1011182123545
. [PMID: 11432631] - R L Schilsky, L Janisch, F Berezin, R Mick, N J Vogelzang, M J Ratain. Phase I clinical and pharmacological study of iododeoxyuridine and bleomycin in patients with advanced cancer.
Cancer research.
1993 Mar; 53(6):1293-6. doi:
NULL
. [PMID: 7680282] - T J Kinsella, P P Dobson, J B Mitchell. Interaction of iododeoxyuridine and its primary metabolite, iodouracil on radiation response.
International journal of radiation oncology, biology, physics.
1986 Aug; 12(8):1519-22. doi:
10.1016/0360-3016(86)90207-5
. [PMID: 3759574] - R W Klecker, J F Jenkins, T J Kinsella, R L Fine, J M Strong, J M Collins. Clinical pharmacology of 5-iodo-2'-deoxyuridine and 5-iodouracil and endogenous pyrimidine modulation.
Clinical pharmacology and therapeutics.
1985 Jul; 38(1):45-51. doi:
10.1038/clpt.1985.132
. [PMID: 4006375] - P L Stetson, U A Shukla, P R Amin, W D Ensminger. High-performance liquid chromatographic method for the determination of bromodeoxyuridine and its major metabolite, bromouracil, in biological fluids.
Journal of chromatography.
1985 May; 341(1):217-22. doi:
10.1016/s0378-4347(00)84032-3
. [PMID: 4019689] - C G ENGLE, R C STEWART. ANTI-HERPETIC ACTIVITY OF 5-IODO-2'-DEOXYURIDINE IN PRESENCE OF ITS DEGRADATION PRODUCTS.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1964 Jan; 115(?):43-5. doi:
10.3181/00379727-115-28825
. [PMID: 14117464]