Iodoacetic acid (BioDeep_00000180053)
human metabolite blood metabolite
代谢物信息卡片
Acid, monoiodoacetic
化学式: C2H3IO2 (185.9177808)
中文名称: 碘乙酸
谱图信息:
最多检出来源 Bos taurus(endogenous) 25%
分子结构信息
SMILES: C(C(=O)O)I
InChI: InChI=1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)
描述信息
D009676 - Noxae > D000477 - Alkylating Agents > D007461 - Iodoacetates
D004791 - Enzyme Inhibitors
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:74571
- PubChem: 5240
- HMDB: HMDB0253518
- ChEMBL: CHEMBL376280
- Wikipedia: Iodoacetic_acid
- MeSH: Iodoacetic Acid
- chemspider: 5050
- CAS: 64-69-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lina Jia, Yingchao Gong, Xinru Jiang, Xianan Fan, Zhenghua Ji, Tianwen Ma, Rui Li, Fangping Liu. Ginkgolide C inhibits ROS-mediated activation of NLRP3 inflammasome in chondrocytes to ameliorate osteoarthritis.
Journal of ethnopharmacology.
2024 May; 325(?):117887. doi:
10.1016/j.jep.2024.117887. [PMID: 38346525] - Shu-Hui Fan, Yuan Chang, Xiao-Yu Xiong, Mai Xiang, Wen-Long Yuan, Xiao-Qian Yang, Wen-Hui Wei, Li Chen, Meng-Nan Cheng, Feng-Hua Zhu, Shi-Jun He, Jian-Ping Zuo, Ze-Min Lin. Reversible SAHH inhibitor ameliorates MIA-induced osteoarthritis of rats through suppressing MEK/ERK pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2024 Jan; 170(?):115975. doi:
10.1016/j.biopha.2023.115975. [PMID: 38070246] - Luis Ângelo Macêdo Santiago, Ana Caroline Santos Ataíde, Danilo de Araújo Morais, Aldilene da Silva Lima, Nathálya Dos Santos Martins, Adriana Vivian Costa Araújo Dourado, Rachel Melo Ribeiro, Lídio Gonçalves Lima-Neto, Joicy Cortez de Sá Sousa, Cláudia Quintino da Rocha, Maria do Socorro de Sousa Cartágenes, Rafael Cardoso Carvalho, Eduardo Martins de Sousa. Bixa orellana ethyl acetate fraction and its isolated compound ellagic acid attenuate the progression of MIA-induced osteoarthritis in rat knees.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Dec; 168(?):115644. doi:
10.1016/j.biopha.2023.115644. [PMID: 37839112] - Kuangyang Yang, Qian Xie, Jiaxin Liao, Na Zhao, Jianhui Liang, Ben Liu, Jianhai Chen, Wenxiang Cheng, Xueling Bai, Peng Zhang, Qian Liu, Bing Song, Junyi Danny Wang, Fanghao Zheng, Chun Hu, Lichu Liu, Lei Chen, Yan Wang. Shang-Ke-Huang-Shui and coptisine alleviate osteoarthritis in the knee of monosodium iodoacetate-induced rats through inhibiting CXCR4 signaling.
Journal of ethnopharmacology.
2023 Jul; 311(?):116476. doi:
10.1016/j.jep.2023.116476. [PMID: 37031825] - Zhizheng Fang, Xiangyu Li, Shujun Lei, Shibin Feng, Chenyu Zhou, Xiaohui Tong, Rongchun Han. Protective effects of Pudilan Tablets against osteoarthritis in mice induced by monosodium iodoacetate.
Scientific reports.
2023 02; 13(1):2760. doi:
10.1038/s41598-023-29976-0. [PMID: 36797333] - Jaromir Jarecki, Izabela Polkowska, Waldemar Kazimierczak, Magdalena Wójciak, Ireneusz Sowa, Sławomir Dresler, Tomasz Blicharski. Assessment of the Impact of Physical Activity on the Musculoskeletal System in Early Degenerative Knee Joint Lesions in an Animal Model.
International journal of molecular sciences.
2023 Feb; 24(4):. doi:
10.3390/ijms24043540. [PMID: 36834951] - Kuangyang Yang, Qian Xie, Tingting Tang, Na Zhao, Jianhui Liang, Yanni Shen, Ziqi Li, Ben Liu, Jianhai Chen, Wenxiang Cheng, Xueling Bai, Peng Zhang, Qian Liu, Bing Song, Chun Hu, Lichu Liu, Yan Wang. Astragaloside IV as a novel CXCR4 antagonist alleviates osteoarthritis in the knee of monosodium iodoacetate-induced rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Jan; 108(?):154506. doi:
10.1016/j.phymed.2022.154506. [PMID: 36403512] - You-Suk Lee, Sung-Min Kim, Eun-Jung Park, Hae-Jeung Lee. Anti-arthritic effects of Schisandra chinensis extract in monosodium iodoacetate-induced osteoarthritis rats.
Inflammopharmacology.
2022 Dec; 30(6):2261-2272. doi:
10.1007/s10787-022-01060-5. [PMID: 36059019] - Qi Wang, Jing Peng, Yang Liu, Yang Tian, Jie Li, Yao-Yao Ren, Jian Gu, Rui Tan. [Therapeutic effects of alkaloids in Tibetan medicine Bangna (Aconiti Penduli et Aconiti Flavi Radix) on osteoarthritis rats and mechanisms].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2022 Sep; 47(17):4715-4722. doi:
10.19540/j.cnki.cjcmm.20220207.704. [PMID: 36164879] - Cemal Orhan, Mehmet Tuzcu, Ali Said Durmus, Nurhan Sahin, Ibrahim Hanifi Ozercan, Patrick Brice Defo Deeh, Abhijeet Morde, Prakash Bhanuse, Manutosh Acharya, Muralidhara Padigaru, Kazim Sahin. Protective effect of a novel polyherbal formulation on experimentally induced osteoarthritis in a rat model.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Jul; 151(?):113052. doi:
10.1016/j.biopha.2022.113052. [PMID: 35588576] - Nora M Aborehab, Mahitab H El Bishbishy. Chondroprotection of fruit peels in a monosodium iodoacetate-induced osteoarthritis rat model via downregulation of Col1A1.
Archiv der Pharmazie.
2022 Jul; 355(7):e2200028. doi:
10.1002/ardp.202200028. [PMID: 35385163] - Yujie Sha, Huan Wu, Yue Guo, Xi Liu, Yan Mo, Qiyuan Yang, Shumao Wei, Kunling Long, Du Lu, Ying Xia, Weiwei Zheng, Zhiheng Su, Xiao Wei. Effects of iodoacetic acid drinking water disinfection byproduct on the gut microbiota and its metabolism in rats.
Journal of environmental sciences (China).
2022 Jul; 117(?):91-104. doi:
10.1016/j.jes.2022.02.048. [PMID: 35725093] - Yun Mi Lee, Eunjung Son, Seung-Hyung Kim, Dong-Seon Kim. Anti-Inflammatory and Analgesic Effects of Schisandra chinensis Leaf Extracts and Monosodium Iodoacetate-Induced Osteoarthritis in Rats and Acetic Acid-Induced Writhing in Mice.
Nutrients.
2022 Mar; 14(7):. doi:
10.3390/nu14071356. [PMID: 35405969] - Xiaoyun Zhang, Rilan Chen, Zilong Liao, Ying Zhu, Yueping Chen, Jianhang Liu, Xia Chen. The Xiaogu San Attenuates Pain and Cartilage Damage in Rats with Monosodium Iodoacetate Induced Osteoarthritis.
Combinatorial chemistry & high throughput screening.
2022; 25(11):1914-1951. doi:
10.2174/1386207325666211008130312. [PMID: 34629040] - Jae In Jung, Hyun Sook Lee, Young Eun Jeon, So Mi Kim, Su Hee Hong, Joo Myung Moon, Cho Young Lim, Yoon Hee Kim, Eun Ji Kim. Anti-inflammatory activity of palmitoylethanolamide ameliorates osteoarthritis induced by monosodium iodoacetate in Sprague-Dawley rats.
Inflammopharmacology.
2021 Oct; 29(5):1475-1486. doi:
10.1007/s10787-021-00870-3. [PMID: 34468900] - Xu-Zhao Li, Shuai-Nan Zhang, Qi Liu, Wu-de Yang, Ying Zhou. The active ingredients analysis of Herba Lysimachiae treating osteoarthritis based on the LC-MS/MS technology and public bioinformatics platforms.
Journal of separation science.
2021 Oct; 44(20):3799-3809. doi:
10.1002/jssc.202100390. [PMID: 34409742] - Kazim Sahin, Osman Kucuk, Cemal Orhan, Mehmet Tuzcu, Ali Said Durmus, Ibrahim Hanifi Ozercan, Nurhan Sahin, Vijaya Juturu. Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis.
Scientific reports.
2021 07; 11(1):14724. doi:
10.1038/s41598-021-94142-3. [PMID: 34282229] - Manal A Abdel-Aziz, Helmy M S Ahmed, Aziza A El-Nekeety, Hafiza A Sharaf, Sekena H Abdel-Aziem, Mosaad A Abdel-Wahhab. Biosynthesis of gold nanoparticles for the treatment of osteoarthritis alone or in combination with Diacerein® in a rat model.
Inflammopharmacology.
2021 Jun; 29(3):705-719. doi:
10.1007/s10787-021-00833-8. [PMID: 34117571] - M S Refat, R Z Hamza, Ama Adam, H A Saad, A A Gobouri, F A Al-Salmi, T Altalhi, S M El-Megharbel. Synthesis of N,N'-bis(1,5-dimethyl-2-phenyl-1,2-dihydro-3-oxopyrazol-4-yl) sebacamide that ameliorate osteoarthritis symptoms and improve bone marrow matrix structure and cartilage alterations induced by monoiodoacetate in the rat model: "Suggested potent anti-inflammatory agent against COVID-19".
Human & experimental toxicology.
2021 Feb; 40(2):325-341. doi:
10.1177/0960327120945779. [PMID: 32840387] - Ga-Yul Min, Jong-Min Park, In-Hwan Joo, Dong-Hee Kim. Inhibition effect of Caragana sinica root extracts on Osteoarthritis through MAPKs, NF-κB signaling pathway.
International journal of medical sciences.
2021; 18(4):861-872. doi:
10.7150/ijms.52330. [PMID: 33456343] - Hamzah Khawaja, Numan Fazal, Faiza Yaqub, Muhammad Rauf Ahmad, Muzaffar Hanif, Muhammad Amin Yousaf, Noreen Latief. Protective and proliferative effect of Aesculus indica extract on stressed human adipose stem cells via downregulation of NF-κB pathway.
PloS one.
2021; 16(10):e0258762. doi:
10.1371/journal.pone.0258762. [PMID: 34679084] - Nur Adeelah Che Ahmad Tantowi, Suhaila Mohamed, Seng Fong Lau, Paisal Hussin. Comparison of diclofenac with apigenin-glycosides rich Clinacanthus nutans extract for amending inflammation and catabolic protease regulations in osteoporotic-osteoarthritis rat model.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences.
2020 Dec; 28(2):443-453. doi:
10.1007/s40199-020-00343-y. [PMID: 32388789] - Mohamed Ali Rebai, Nizar Sahnoun, Oussema Abdelhedi, Khaled Keskes, Slim Charfi, Fathia Slimi, Rim Frikha, Hassib Keskes. Animal models of osteoarthritis: characterization of a model induced by Mono-Iodo-Acetate injected in rabbits.
The Libyan journal of medicine.
2020 Dec; 15(1):1753943. doi:
10.1080/19932820.2020.1753943. [PMID: 32281500] - Hae Lim Kim, Hae Jin Lee, Dong-Ryung Lee, Bong-Keun Choi, Seung Hwan Yang. Herbal Composition LI73014F2 Alleviates Articular Cartilage Damage and Inflammatory Response in Monosodium Iodoacetate-Induced Osteoarthritis in Rats.
Molecules (Basel, Switzerland).
2020 Nov; 25(22):. doi:
10.3390/molecules25225467. [PMID: 33238379] - Mi Hye Kim, La Yoon Choi, Kwang Seok Ahn, Jae-Young Um, Seok-Geun Lee, Dae-Hyun Hahm, Woong Mo Yang. Gumiganghwal-tang ameliorates cartilage destruction via inhibition of matrix metalloproteinase.
Journal of ethnopharmacology.
2020 Oct; 261(?):113074. doi:
10.1016/j.jep.2020.113074. [PMID: 32534115] - Dinesh Kumar Lakshmanan, Guna Ravichandran, Abbirami Elangovan, Preethi Jeyapaul, Selvakumar Murugesan, Sivasudha Thilagar. Cissus quadrangularis (veldt grape) attenuates disease progression and anatomical changes in mono sodium iodoacetate (MIA)-induced knee osteoarthritis in the rat model.
Food & function.
2020 Sep; 11(9):7842-7855. doi:
10.1039/d0fo00992j. [PMID: 32812575] - Linjie Ju, Peipei Hu, Ping Chen, Xue Xue, Zhuoqun Li, Feiyan He, Zhixia Qiu, Jun Cheng, Fang Huang. Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/ Akt/ NF-κB pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Sep; 129(?):110471. doi:
10.1016/j.biopha.2020.110471. [PMID: 32768958] - Elena G Yarmola, Yash Y Shah, Emily H Lakes, Yan C Pacheco, Danny F Xie, Jon Dobson, Kyle D Allen. Use of magnetic capture to identify elevated levels of CCL2 following intra-articular injection of monoiodoacetate in rats.
Connective tissue research.
2020 09; 61(5):485-497. doi:
10.1080/03008207.2019.1620223. [PMID: 31438731] - Yuan Li, Fan Wu, Li Xing Lao, Xue Yong Shen. Laser irradiation activates spinal adenosine A1 receptor to alleviate osteoarthritis pain in monosodium iodoacetate injected rats.
Journal of integrative neuroscience.
2020 Jun; 19(2):295-302. doi:
10.31083/j.jin.2020.02.33. [PMID: 32706193] - Laura Micheli, Lorenzo Di Cesare Mannelli, Luisa Mattoli, Sara Tamimi, Enrico Flamini, Stefano Garetto, Jacopo Lucci, Emiliano Giovagnoni, Lorenzo Cinci, Mario D'Ambrosio, Cristina Luceri, Carla Ghelardini. Intra-Articular Route for the System of Molecules 14G1862 from Centella Asiatica: Pain Relieving and Protective Effects in a Rat Model of Osteoarthritis.
Nutrients.
2020 May; 12(6):. doi:
10.3390/nu12061618. [PMID: 32486519] - Donghun Lee, Mi-Kyoung Ju, Hocheol Kim. Commiphora Extract Mixture Ameliorates Monosodium Iodoacetate-Induced Osteoarthritis.
Nutrients.
2020 May; 12(5):. doi:
10.3390/nu12051477. [PMID: 32438772] - Jae Hyun Jung, Sung Eun Kim, Hak-Jun Kim, Kyeongsoon Park, Gwan Gyu Song, Sung Jae Choi. A comparative pilot study of oral diacerein and locally treated diacerein-loaded nanoparticles in a model of osteoarthritis.
International journal of pharmaceutics.
2020 May; 581(?):119249. doi:
10.1016/j.ijpharm.2020.119249. [PMID: 32217157] - Yuan Li, Fan Wu, Jianzi Wei, Lixing Lao, Xueyong Shen. Laser Moxibustion Alleviates Knee Osteoarthritis Pain by Inhibiting Spinal Microglial Activation-Mediated Neuroinflammation in Rats.
Photobiomodulation, photomedicine, and laser surgery.
2020 Apr; 38(4):237-243. doi:
10.1089/photob.2019.4744. [PMID: 31976816] - Paco Romero, Fernando Alférez, Beatriz Establés-Ortiz, María T Lafuente. Insights into the regulation of molecular mechanisms involved in energy shortage in detached citrus fruit.
Scientific reports.
2020 01; 10(1):1109. doi:
10.1038/s41598-019-57012-7. [PMID: 31980654] - Yuan Li, Fan Wu, Jianzi Wei, Lixing Lao, Xueyong Shen. The Effects of Laser Moxibustion on Knee Osteoarthritis Pain in Rats.
Photobiomodulation, photomedicine, and laser surgery.
2020 Jan; 38(1):43-50. doi:
10.1089/photob.2019.4716. [PMID: 31549920] - Taiyang Liao, Liang Ding, Peng Wu, Li Zhang, Xiaochen Li, Bo Xu, Haosheng Zhang, Zhenyuan Ma, Yancheng Xiao, Peimin Wang. Chrysin Attenuates the NLRP3 Inflammasome Cascade to Reduce Synovitis and Pain in KOA Rats.
Drug design, development and therapy.
2020; 14(?):3015-3027. doi:
10.2147/dddt.s261216. [PMID: 32801641] - Lijun Tian, Zhiyong Su, Xiaobin Ma, Feng Wang, Yusong Guo. Inhibition of miR-203 Ameliorates Osteoarthritis Cartilage Degradation in the Postmenopausal Rat Model: Involvement of Estrogen Receptor α.
Human gene therapy. Clinical development.
2019 12; 30(4):160-168. doi:
10.1089/humc.2019.101. [PMID: 31711313] - Marika Cordaro, Rosalba Siracusa, Daniela Impellizzeri, Ramona D' Amico, Alessio Filippo Peritore, Rosalia Crupi, Enrico Gugliandolo, Roberta Fusco, Rosanna Di Paola, Carlo Schievano, Salvatore Cuzzocrea. Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain.
Arthritis research & therapy.
2019 11; 21(1):254. doi:
10.1186/s13075-019-2048-y. [PMID: 31779692] - Doo Jin Choi, Soo-Im Choi, Bo-Ram Choi, Young-Seob Lee, Dae Young Lee, Geum Soog Kim. Cartilage protective and anti-analgesic effects of ALM16 on monosodium iodoacetate induced osteoarthritis in rats.
BMC complementary and alternative medicine.
2019 Nov; 19(1):325. doi:
10.1186/s12906-019-2746-7. [PMID: 31752825] - Cleydlenne Costa Vasconcelos, Alberto Jorge Oliveira Lopes, Emerson Lucas Frazão Sousa, Darleno Sousa Camelo, Fernando César Vilhena Moreira Lima, Cláudia Quintino da Rocha, Gyl Eanes Barros Silva, João Batista Santos Garcia, Maria do Socorro de Sousa Cartágenes. Effects of Extract of Arrabidaea chica Verlot on an Experimental Model of Osteoarthritis.
International journal of molecular sciences.
2019 Sep; 20(19):. doi:
10.3390/ijms20194717. [PMID: 31547612] - Qiong Wu, Huiming Yuan, Yejing Weng, Zhigang Sui, Xiaodan Zhang, Yechen Hu, Zhen Liang, Lihua Zhang, Yukui Zhang. [A novel method for the selective enrichment of persulfidated peptides based on iodoacetic acid functionalized dendrimer].
Se pu = Chinese journal of chromatography.
2019 Aug; 37(8):836-844. doi:
10.3724/sp.j.1123.2019.03017. [PMID: 31642254] - Yun Zhang, Yu Zeng. Curcumin reduces inflammation in knee osteoarthritis rats through blocking TLR4 /MyD88/NF-κB signal pathway.
Drug development research.
2019 05; 80(3):353-359. doi:
10.1002/ddr.21509. [PMID: 30663793] - Fang Yang, Diantao Jing, Dawei Yu, Wenshui Xia, Qixing Jiang, Yanshun Xu, Peipei Yu. Differential roles of ice crystal, endogenous proteolytic activities and oxidation in softening of obscure pufferfish (Takifugu obscurus) fillets during frozen storage.
Food chemistry.
2019 Apr; 278(?):452-459. doi:
10.1016/j.foodchem.2018.11.084. [PMID: 30583396] - Caiwei Wang, Li Yan, Bo Yan, Li Zhou, Wan Sun, Lingying Yu, Fucun Liu, Wenxi Du, Guangping Yu, Zhengyan Hu, Qiang Yuan, Luwei Xiao, Hongwen Li, Peijian Tong, Jida Zhang, Letian Shan, Thomas Efferth. Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis.
Journal of ethnopharmacology.
2019 Mar; 231(?):545-554. doi:
10.1016/j.jep.2018.12.004. [PMID: 30529425] - S Azizi, A Farsinejad, R Kheirandish, H Fatemi. Intra-articular effects of combined xenogenous serum rich in growth factors (SRGF) and vitamin C on histopathology grading and staging of osteoarthritis in rat model.
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine.
2019 Feb; 26(1):3-9. doi:
10.1016/j.tracli.2018.08.156. [PMID: 30193926] - Waleed N Hassan, Ismaeel Bin-Jaliah, Mohamed A Haidara, Refaat A Eid, El Hassan A Heidar, Mohammad Dallak, Bahjat Al-Ani. Vitamin E ameliorates alterations to the articular cartilage of knee joints induced by monoiodoacetate and diabetes mellitus in rats.
Ultrastructural pathology.
2019; 43(2-3):126-134. doi:
10.1080/01913123.2019.1627446. [PMID: 31177887] - Y Aman, T Pitcher, C Ballard, M Malcangio. Impaired chronic pain-like behaviour and altered opioidergic system in the TASTPM mouse model of Alzheimer's disease.
European journal of pain (London, England).
2019 01; 23(1):91-106. doi:
10.1002/ejp.1288. [PMID: 29987897] - Oleksandr Korotkyi, Andrii Vovk, Oksana Blokhina, Kateryna Dvorshchenko, Tetyana Falalyeyeva, Ludovico Abenavoli, Liudmyla Ostapchenko. Effect of Chondroitin Sulfate on Blood Serum Cytokine Profile during Carrageenan-induced Edema and Monoiodoacetate-induced Osteoarthritis in Rats.
Reviews on recent clinical trials.
2019; 14(1):50-55. doi:
10.2174/1574887113666181102111247. [PMID: 30387401] - Jeong-Min Hong, Jun-Kyu Shin, Jeom-Yong Kim, Min-Jung Jang, Sun-Kyu Park, Jong-Hoon Lee, Jung-Hyo Choi, Sun-Mee Lee. BST106 Protects against Cartilage Damage by Inhibition of Apoptosis and Enhancement of Autophagy in Osteoarthritic Rats.
Biological & pharmaceutical bulletin.
2018 Aug; 41(8):1257-1268. doi:
10.1248/bpb.b18-00207. [PMID: 29794403] - Jin Mi Chun, A Yeong Lee, Joong Sun Kim, Goya Choi, Seung-Hyung Kim. Protective Effects of Peucedanum japonicum Extract against Osteoarthritis in an Animal Model Using a Combined Systems Approach for Compound-Target Prediction.
Nutrients.
2018 Jun; 10(6):. doi:
10.3390/nu10060754. [PMID: 29891807] - Aliaa S A Al-Afify, Gehan El-Akabawy, Neveen M El-Sherif, Fatma El-Nabawya A El-Safty, Mostafa M El-Habiby. Avocado soybean unsaponifiables ameliorates cartilage and subchondral bone degeneration in mono-iodoacetate-induced knee osteoarthritis in rats.
Tissue & cell.
2018 Jun; 52(?):108-115. doi:
10.1016/j.tice.2018.05.001. [PMID: 29857819] - Vasu Karlapudi, Anjaneya Venkata Vara Prasad Mungara, Krishanu Sengupta, Barbara A Davis, Siba Prasad Raychaudhuri. A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of Knee.
Journal of medicinal food.
2018 May; 21(5):511-520. doi:
10.1089/jmf.2017.0065. [PMID: 29708818] - Ji Ye Kwon, Seung Hoon Lee, JooYeon Jhun, JeongWon Choi, KyungAh Jung, Keun Hyung Cho, Seok Jung Kim, Chul Woo Yang, Sung-Hwan Park, Mi-La Cho. The Combination of Probiotic Complex, Rosavin, and Zinc Improves Pain and Cartilage Destruction in an Osteoarthritis Rat Model.
Journal of medicinal food.
2018 Apr; 21(4):364-371. doi:
10.1089/jmf.2017.4034. [PMID: 29346012] - Po-Wei Tsai, Yi-Hui Lee, Lih-Geeng Chen, Chia-Jung Lee, Ching-Chiung Wang. In Vitro and In Vivo Anti-Osteoarthritis Effects of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-Glucoside from Polygonum Multiflorum.
Molecules (Basel, Switzerland).
2018 Mar; 23(3):. doi:
10.3390/molecules23030571. [PMID: 29510478] - Alla I Perfileva, Antonina G Pavlova, Baira B Bukhyanova, Olga M Tsivileva. Pesticides impact on Clavibacter michiganensis ssp. sepedonicus biofilm formation.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2018; 53(7):464-468. doi:
10.1080/03601234.2018.1455356. [PMID: 29624494] - Yashashri C Shetty, Santosh Godbharle, Smita Brahma, Sweta Salgaonkar, Nirmala N Rege. Evaluation of oral multi-herbal preparation of Dashmoolarishta on mice model of osteoarthritis.
Journal of basic and clinical physiology and pharmacology.
2017 Nov; 28(6):583-591. doi:
10.1515/jbcpp-2016-0141. [PMID: 29040066] - Tomonari Watabiki, Noriko Tsuji, Tetsuo Kiso, Tohru Ozawa, Fumie Narazaki, Shuichiro Kakimoto. In vitro and in vivo pharmacological characterization of ASP8477: A novel highly selective fatty acid amide hydrolase inhibitor.
European journal of pharmacology.
2017 Nov; 815(?):42-48. doi:
10.1016/j.ejphar.2017.10.007. [PMID: 29017758] - Barbara Tenci, Lorenzo Di Cesare Mannelli, Mario Maresca, Laura Micheli, Giuseppe Pieraccini, Nadia Mulinacci, Carla Ghelardini. Effects of a water extract of Lepidium meyenii root in different models of persistent pain in rats.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2017 Oct; 72(11-12):449-457. doi:
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Molecular medicine reports.
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