(9S)-9-Acetyl-7-[(2R,4S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione (BioDeep_00000179964)
human metabolite blood metabolite
代谢物信息卡片
(9S)-9-Acetyl-7-[(2R,4S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
化学式: C26H27NO9 (497.1685732000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O
InChI: InChI=1S/C26H27NO9/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3
描述信息
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
D004791 - Enzyme Inhibitors
同义名列表
13 个代谢物同义名
(9S)-9-Acetyl-7-[(2R,4S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione; 9-acetyl-7-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,9,11-trihydroxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione; 9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione; Hydrochloride, idarubicin; 4 Desmethoxydaunorubicin; Idarubicin hydrochloride; 4-Desmethoxydaunorubicin; 4-Demethoxydaunorubicin; 4 Demethoxydaunorubicin; Idarubicin; IMI-30; IMI 30; IMI30
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jie Ding, Yang Su, Yinglu Ruan, Nan Li, Qianchao Meng, Jiabang Yang, Li Chen, Chi Liu. Clinical features and outcomes of patients with acute myeloid leukemia: the single-center experience of 668 patients in China.
Hematology (Amsterdam, Netherlands).
2024 Dec; 29(1):2310960. doi:
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Environmental research.
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Journal of colloid and interface science.
2021 Jan; 581(Pt A):403-416. doi:
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Leukemia research.
2021 01; 100(?):106480. doi:
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Molecules (Basel, Switzerland).
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Hematological oncology.
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Blood.
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Medical oncology (Northwood, London, England).
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Bioelectrochemistry (Amsterdam, Netherlands).
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Neoplasma.
2005; 52(5):430-4. doi:
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European journal of haematology.
2004 Dec; 73(6):441-6. doi:
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Anticancer research.
2004 May; 24(3a):1759-63. doi:
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Journal of chemotherapy (Florence, Italy).
2004 Apr; 16(2):193-200. doi:
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Cancer chemotherapy and pharmacology.
2004 Jan; 53(1):61-7. doi:
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Neuro-oncology.
2003 Oct; 5(4):261-7. doi:
10.1215/s115285170200056x. [PMID: 14565163] - Jiroh Yamasaki, Tomoko Hata, Kengo Fuchigami, Katsuhiro Togami, Miyuki Honda, Takuya Fukushima, Yasushi Miyazaki, Itsuro Jinnai, Kazutaka Kuriyama, Masao Tomonaga. [Intensive multi-drug chemotherapy for acute myeloid leukemia in a renal allograft recipient].
[Rinsho ketsueki] The Japanese journal of clinical hematology.
2003 Oct; 44(10):1015-9. doi:
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Veterinary research communications.
2003 Sep; 27 Suppl 1(?):385-9. doi:
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International journal of hematology.
2003 Aug; 78(2):149-53. doi:
10.1007/bf02983384. [PMID: 12953810] - B Myers, H Lachmann, N H Russell. Novel combination chemotherapy for primary (AL) amyloidosis myeloma: clinical, laboratory and serum amyloid-P protein scan improvement.
British journal of haematology.
2003 Jun; 121(5):816-7. doi:
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International journal of clinical pharmacology and therapeutics.
2002 Aug; 40(8):329-35. doi:
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Journal of pharmaceutical sciences.
2002 May; 91(5):1324-33. doi:
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La Clinica terapeutica.
2002 May; 153(3):207-15. doi:
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Biochimica et biophysica acta.
2002 Apr; 1561(2):188-201. doi:
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International journal of hematology.
2001 Oct; 74(3):297-302. doi:
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European journal of drug metabolism and pharmacokinetics.
2001 Oct; 26(4):215-9. doi:
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Transplantation.
2001 Sep; 72(6):1150-2. doi:
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Anti-cancer drugs.
2001 Sep; 12(8):677-80. doi:
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International journal of pharmaceutics.
2001 Jun; 220(1-2):43-51. doi:
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Annals of hematology.
2001 Apr; 80(4):246-50. doi:
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Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2001 Mar; 32(5):E87-9. doi:
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Leukemia.
2001 Jan; 15(1):80-8. doi:
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Electrophoresis.
2001 Jan; 22(1):134-8. doi:
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Fresenius' journal of analytical chemistry.
2000 Dec; 368(8):844-7. doi:
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Research in veterinary science.
2000 Dec; 69(3):255-62. doi:
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Toxicology.
2000 Nov; 155(1-3):83-90. doi:
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International journal of oncology.
2000 Sep; 17(3):591-5. doi:
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Bone marrow transplantation.
2000 Sep; 26(6):615-20. doi:
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International journal of clinical pharmacology and therapeutics.
2000 Apr; 38(4):217-21. doi:
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Journal of cancer research and clinical oncology.
2000 Feb; 126(2):111-6. doi:
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European journal of biochemistry.
2000 Feb; 267(3):649-57. doi:
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Archives of pathology & laboratory medicine.
2000 Feb; 124(2):315-8. doi:
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Anticancer research.
2000 Jan; 20(1A):33-42. doi:
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Medicina.
2000; 60(1):143-5. doi:
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Journal of pharmaceutical sciences.
1999 Dec; 88(12):1340-7. doi:
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Leukemia & lymphoma.
1999 Nov; 35(5-6):623-6. doi:
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Leukemia & lymphoma.
1999 Nov; 35(5-6):593-7. doi:
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Blood.
1999 Oct; 94(7):2230-5. doi:
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Journal of neuro-oncology.
1999 Aug; 44(1):65-9. doi:
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Bone marrow transplantation.
1999 Aug; 24(4):433-5. doi:
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European journal of clinical pharmacology.
1999 Jul; 55(5):369-73. doi:
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Therapeutic drug monitoring.
1999 Jun; 21(3):367-75. doi:
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Cytometry.
1999 Jun; 36(2):140-9. doi:
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Journal of chromatography. B, Biomedical sciences and applications.
1999 May; 728(2):279-82. doi:
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