N,N-Diallyl-tyrosyl-aminoisobutyryl-aminoisobutyryl-phenylalanyl-leucine (BioDeep_00000179918)

   

human metabolite blood metabolite


代谢物信息卡片


2-({2-[(2-{[2-({2-[bis(prop-2-en-1-yl)amino]-1-hydroxy-3-(4-hydroxyphenyl)propylidene}amino)-1-hydroxy-2-methylpropylidene]amino}-1-hydroxy-2-methylpropylidene)amino]-1-hydroxy-3-phenylpropylidene}amino)-4-methylpentanoate

化学式: C38H53N5O7 (691.3944787999999)
中文名称:
谱图信息: 最多检出来源 Rattus norvegicus(blood) 92.31%

分子结构信息

SMILES: CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)C(CC2=CC=C(C=C2)O)N(CC=C)CC=C
InChI: InChI=1S/C38H53N5O7/c1-9-20-43(21-10-2)31(24-27-16-18-28(44)19-17-27)33(46)41-38(7,8)36(50)42-37(5,6)35(49)40-29(23-26-14-12-11-13-15-26)32(45)39-30(34(47)48)22-25(3)4/h9-19,25,29-31,44H,1-2,20-24H2,3-8H3,(H,39,45)(H,40,49)(H,41,46)(H,42,50)(H,47,48)



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • R Frithiof, S Eriksson, M Rundgren. Central inhibition of opioid receptor subtypes and its effect on haemorrhagic hypotension in conscious sheep. Acta physiologica (Oxford, England). 2007 Sep; 191(1):25-34. doi: 10.1111/j.1748-1716.2007.01720.x. [PMID: 17550406]
  • G Piñeyro, M Azzi, A De Léan, P Schiller, M Bouvier. Short-term inverse-agonist treatment induces reciprocal changes in delta-opioid agonist and inverse-agonist binding capacity. Molecular pharmacology. 2001 Oct; 60(4):816-27. doi: . [PMID: 11562445]
  • P Li, S Tjen-A-Looi, J C Longhurst. Rostral ventrolateral medullary opioid receptor subtypes in the inhibitory effect of electroacupuncture on reflex autonomic response in cats. Autonomic neuroscience : basic & clinical. 2001 Jun; 89(1-2):38-47. doi: 10.1016/s1566-0702(01)00247-8. [PMID: 11474645]
  • T Iu Rebrova, L N Maslov, Iu B Lishmanov, S V Tam. [The role of mu- and delta-opiate receptors in resistance of the myocardium to free radical damage]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 2001 May; 87(5):628-41. doi: ". [PMID: 11452797]
  • Iu B Lishmanov, L A Maĭmeskulova, E V Uskina, L N Maslov. [Opiatergic mechanisms of cardioprotective and anti-arrhythmic effects of adaptation]. Biulleten' eksperimental'noi biologii i meditsiny. 1999 Feb; 127(2):167-70. doi: ". [PMID: 10095946]
  • L A Maĭmeskulova, L N Maslov, Iu B Lishmanov, E A Krasnov. [The participation of the mu-, delta- and kappa-opioid receptors in the realization of the anti-arrhythmia effect of Rhodiola rosea]. Eksperimental'naia i klinicheskaia farmakologiia. 1997 Jan; 60(1):38-9. doi: ". [PMID: 9162281]
  • T T Chiu, L Y Yung, Y H Wong. Inverse agonistic effect of ICI-174,864 on the cloned delta-opioid receptor: role of G protein and adenylyl cyclase activation. Molecular pharmacology. 1996 Dec; 50(6):1651-7. doi: . [PMID: 8967989]
  • J Garzón, M A Castro, J L Juarros, P Sánchez-Blázquez. Antibodies raised against the N-terminal sequence of delta opioid receptors blocked delta-mediated supraspinal antinociception in mice. Life sciences. 1994; 54(11):PL191-6. doi: 10.1016/0024-3205(94)90167-8. [PMID: 8107515]
  • L Gozariu, M S Gozariu, P Orbai, V Sandor, H Schmidt-Gayk. The mechanism involved in the central effect of 5-leu enkephalin on the calcitonin secretion. Romanian journal of endocrinology. 1993; 31(1-2):49-55. doi: NULL. [PMID: 7909701]
  • F R Cagampang, K Maeda. Effects of intracerebroventricular administration of opiate receptor antagonists on the suppressed pulsatile LH release during acute fasting in ovariectomized estradiol-treated rats. Life sciences. 1991; 49(24):1823-8. doi: 10.1016/0024-3205(91)90484-s. [PMID: 1658522]
  • J A Kiritsy-Roy, L Marson, G R Van Loon. Sympathoadrenal, cardiovascular and blood gas responses to highly selective mu and delta opioid peptides. The Journal of pharmacology and experimental therapeutics. 1989 Dec; 251(3):1096-103. doi: . [PMID: 2557411]
  • L Marson, J A Kiritsy-Roy, G R Van Loon. mu-Opioid peptide modulation of cardiovascular and sympathoadrenal responses to stress. The American journal of physiology. 1989 Oct; 257(4 Pt 2):R901-8. doi: 10.1152/ajpregu.1989.257.4.r901. [PMID: 2552846]
  • P O Cover, J C Buckingham. Effects of selective opioid-receptor blockade on the hypothalamo-pituitary-adrenocortical responses to surgical trauma in the rat. The Journal of endocrinology. 1989 May; 121(2):213-20. doi: 10.1677/joe.0.1210213. [PMID: 2547002]
  • S L Hart, H Slusarczyk, T W Smith. The effects of selective opioid delta-receptor antagonists on stress-induced antinociception and plasma corticosterone levels in mice. Neuropeptides. 1985 Feb; 5(4-6):303-6. doi: 10.1016/0143-4179(85)90013-7. [PMID: 3839053]