N,N-Bis(allyl)-tyr-gly-gly-psi-methylthio-phe-leu (BioDeep_00000179915)
human metabolite blood metabolite
代谢物信息卡片
化学式: C34H46N4O6S (638.3137896000001)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 50%
分子结构信息
SMILES: CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)SCCNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N(CC=C)CC=C
InChI: InChI=1S/C34H46N4O6S/c1-5-17-38(18-6-2)29(21-26-12-14-27(39)15-13-26)32(41)36-23-31(40)35-16-19-45-30(22-25-10-8-7-9-11-25)33(42)37-28(34(43)44)20-24(3)4/h5-15,24,28-30,39H,1-2,16-23H2,3-4H3,(H,35,40)(H,36,41)(H,37,42)(H,43,44)
描述信息
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D009292 - Narcotic Antagonists
D018377 - Neurotransmitter Agents > D018847 - Opioid Peptides
D018377 - Neurotransmitter Agents > D004745 - Enkephalins
同义名列表
6 个代谢物同义名
2-(2-{[2-(2-{2-[bis(prop-2-en-1-yl)amino]-3-(4-hydroxyphenyl)propanamido}acetamido)ethyl]sulfanyl}-3-phenylpropanamido)-4-methylpentanoic acid; N,N-Bis(allyl)-tyrosyl-glycyl-glycyl-psi-methylthio-phenylalanyl-leucine; N,N-Bis(allyl)-tyr-gly-gly-psi-methylthio-phe-leu; Ici154129;ici 154129;M 154129;M154129;M-154129; ICI 154129, (R-(r*,s*))-isomer; ICI 154129, (S-(r*,r*))-isomer
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Luying Cui, Hele Cai, Fazhuang Sun, Yali Wang, Yang Qu, Junsheng Dong, Heng Wang, Jun Li, Chen Qian, Jianji Li. Beta-endorphin inhibits the inflammatory response of bovine endometrial cells through δ opioid receptor in vitro.
Developmental and comparative immunology.
2021 08; 121(?):104074. doi:
10.1016/j.dci.2021.104074. [PMID: 33775662] - N Imai, M Kashiki, P D Woolf, C S Liang. Comparison of cardiovascular effects of mu- and delta-opioid receptor antagonists in dogs with congestive heart failure.
The American journal of physiology.
1994 Sep; 267(3 Pt 2):H912-7. doi:
10.1152/ajpheart.1994.267.3.h912. [PMID: 8092295] - R Hashimoto, F Kimura. Effects of intraventricular injection of delta receptor antagonist ICI 154, 129 on the secretion of luteinizing hormone and prolactin in the proestrous rat.
Endocrinologia japonica.
1991 Apr; 38(2):213-8. doi:
10.1507/endocrj1954.38.213. [PMID: 1661235] - S Sakamoto, C S Liang. Opiate receptor inhibition improves the blunted baroreflex function in conscious dogs with right-sided congestive heart failure.
Circulation.
1989 Oct; 80(4):1010-5. doi:
10.1161/01.cir.80.4.1010. [PMID: 2551535] - S Ferri, E Cavicchini, P Romualdi, E Speroni, G Murari. Possible mediation of catecholaminergic pathways in the antinociceptive effect of an extract of Cannabis sativa L.
Psychopharmacology.
1986; 89(2):244-7. doi:
10.1007/bf00310637. [PMID: 3088644] - A E Panerai, F Petraglia, P Sacerdote, A R Genazzani. Mainly mu-opiate receptors are involved in luteinizing hormone and prolactin secretion.
Endocrinology.
1985 Sep; 117(3):1096-9. doi:
10.1210/endo-117-3-1096. [PMID: 2990867] - S L Hart, H Slusarczyk, T W Smith. The effects of selective opioid delta-receptor antagonists on stress-induced antinociception and plasma corticosterone levels in mice.
Neuropeptides.
1985 Feb; 5(4-6):303-6. doi:
10.1016/0143-4179(85)90013-7. [PMID: 3839053] - R J Barrett, J A Turpin, B A McGuirk, S T Kau. Lack of renal tubular and hemodynamic effects of non-selective and delta-opioid receptor antagonism.
Pharmacological research communications.
1985 Jan; 17(1):49-61. doi:
10.1016/0031-6989(85)90051-7. [PMID: 3983226] - J B Wiesner, J I Koenig, L Krulich, R L Moss. Possible delta receptor mediation of the effect of beta-endorphin on luteinizing hormone (LH) release, but not on prolactin (PRL) release, in the ovariectomized rat.
Endocrinology.
1985 Jan; 116(1):475-7. doi:
10.1210/endo-116-1-475. [PMID: 2981076] - I Kitchen, K M Rowan. Differences in the effects of mu- and delta-opioid receptor antagonists upon plasma corticosterone levels in stressed mice.
European journal of pharmacology.
1984 May; 101(1-2):153-6. doi:
10.1016/0014-2999(84)90042-6. [PMID: 6086360]