Etamiphylline (BioDeep_00000017987)

   

human metabolite


代谢物信息卡片


7-[2-(diethylamino)ethyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

化学式: C13H21N5O2 (279.1695166)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCN(CC)CCN1C=NC2=C1C(=O)N(C(=O)N2C)C
InChI: InChI=1S/C13H21N5O2/c1-5-17(6-2)7-8-18-9-14-11-10(18)12(19)16(4)13(20)15(11)3/h9H,5-8H2,1-4H3

描述信息

Etamiphylline belongs to the family of Xanthines. These are purine derivatives with a ketone group conjugated at carbons 2 and 6 of the purine moiety.
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03D - Other systemic drugs for obstructive airway diseases > R03DA - Xanthines
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent > C319 - Bronchodilator
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor

同义名列表

33 个代谢物同义名

7-[2-(diethylamino)ethyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; {7-[2-(diethylamino)ethyl]-1,} 3-dimethylxanthine; 1, {3-dimethyl-7-[2-(diethylamino)ethyl]xanthine}; 1,3-Dimethyl-7-(2-(diethylamino)ethyl)xanthine; 7-(2-(Diethylamino)ethyl)-1,3-dimethylxanthine; Theophylline, {7-[2-(diethylamino)ethyl]-}; {7-[2-(diethylamino)ethyl]theophylline}; 7-(2-(Diethylamino)ethyl)-theophylline; {7-[(diethylamino)ethyl]theophylline}; 7-(2-(Diethylamino)ethyl)theophylline; 7-(Diethylaminoethyl)theophylline; Diaethylaminoaethyl-theophyllin; Etamiphyllin monohydrochloride; Etamiphylline camphorsulfonate; Diethylaminoethyltheophylline; Etamiphylline hydrochloride; Etamiphylline camsylate; Etaminophylline; DIETAMIPHYLLINE; Camphophylline; Milliphylline; Millophylline; Etamiphylline; Camphophyline; Ethamicyclin; Etamiphyllin; Millophyline; Parephyllin; Soluphyline; Solucyclin; Solufilina; Corafil; Queryl



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • M E Wieder, P R Brown, L Grainger, P Teale. Identification of etamiphylline and metabolites in equine plasma and urine by accurate mass and liquid chromatography/tandem mass spectrometry. Drug testing and analysis. 2010 Jun; 2(6):271-7. doi: 10.1002/dta.133. [PMID: 20564606]
  • M C Dumasia, P Teale. N-deethylation and N-oxidation of etamiphylline: identification of etamiphylline-N-oxide in greyhound urine by high performance liquid chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2005 Jan; 36(5):1085-91. doi: 10.1016/j.jpba.2004.09.005. [PMID: 15620536]
  • M Elghazali, I A Wasfi, N A Al Katheeri, A A A Hadi, M M Hussein. The pharmacokinetics, metabolism and urinary detection time of etamiphylline in camels after intramuscular administration. Journal of veterinary pharmacology and therapeutics. 2002 Feb; 25(1):43-8. doi: 10.1046/j.1365-2885.2002.00383.x. [PMID: 11874526]
  • A Torres, J Rovira, D Zapatero, J Vilageliu, M Ribalta, L Bruseghini. [Serum levels and urinary and fecal excretion of ethamicylin HCI (solucylin). Oral and intravenous administration (author's transl)]. Archivos de farmacologia y toxicologia. 1980 Dec; 6(3):237-46. doi: NULL. [PMID: 7305455]