1-O-Hexyl-2,3,5-trimethylhydroquinone (BioDeep_00000179813)
human metabolite blood metabolite
代谢物信息卡片
化学式: C15H24O2 (236.1776204)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCOC1=C(C(=C(C(=C1)C)O)C)C
InChI: InChI=1S/C15H24O2/c1-5-6-7-8-9-17-14-10-11(2)15(16)13(4)12(14)3/h10,16H,5-9H2,1-4H3
描述信息
同义名列表
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 119193
- HMDB: HMDB0253220
- DrugBank: DB12162
- ChEMBL: CHEMBL3182532
- CAS: 148081-72-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hye Young Kim, Sang Bong Ahn, Jeong-Min Hong, Ju Hee Oh, Waqar Khalid Saeed, Gyu Sik Kim, Hyun Kim, Jong Koo Kang, Sukmo Kang, Dae Won Jun. BTT-105 ameliorates hepatic fibrosis in non-alcoholic fatty liver animal model.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2021 11; 35(11):e21979. doi:
10.1096/fj.202002656rrr. [PMID: 34694029] - Chaoliang Tang, Yida Hu, Haiyan Lyu, Jie Gao, Jiazhen Jiang, Xiude Qin, Yuanbo Wu, Jiawu Wang, Xiaoqing Chai. Neuroprotective effects of 1-O-hexyl-2,3,5-trimethylhydroquinone on ischaemia/reperfusion-induced neuronal injury by activating the Nrf2/HO-1 pathway.
Journal of cellular and molecular medicine.
2020 09; 24(18):10468-10477. doi:
10.1111/jcmm.15659. [PMID: 32677362] - Hyun Jin Park, Jong Koo Kang, Myung Koo Lee. 1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells.
Molecules (Basel, Switzerland).
2019 Mar; 24(5):. doi:
10.3390/molecules24050867. [PMID: 30823626] - Yo Han Kim, Hee Youn Choi, Shi Hyang Lee, Hyeong-Seok Lim, Tokutaro Miki, Jong-Koo Kang, Kyoung-Goo Han, Kyun-Seop Bae. Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers.
Drug design, development and therapy.
2015; 9(?):1735-42. doi:
10.2147/dddt.s79724. [PMID: 25848210] - Taha S El-Alfy, Hamida M A El-Gohary, Nadia M Sokkar, Mohammed Hosny, Dalia A Al-Mahdy. A New Flavonoid C-Glycoside from Celtis australis L. and Celtis occidentalis L. Leaves and Potential Antioxidant and Cytotoxic Activities.
Scientia pharmaceutica.
2011 Oct; 79(4):963-75. doi:
10.3797/scipharm.1108-19. [PMID: 22145118] - Masao Hirose, Akiyoshi Nishikawa, Makoto Shibutani, Toshio Imai, Tomoyuki Shirai. Chemoprevention of heterocyclic amine-induced mammary carcinogenesis in rats.
Environmental and molecular mutagenesis.
2002; 39(2-3):271-8. doi:
10.1002/em.10066. [PMID: 11921198] - M Hirose, S Takahashi, K Ogawa, M Futakuchi, T Shirai. Phenolics: blocking agents for heterocyclic amine-induced carcinogenesis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1999 Sep; 37(9-10):985-92. doi:
10.1016/s0278-6915(99)00092-7. [PMID: 10541455] - T Hino, S Kawanishi, H Yasui, S Oka, H Sakurai. HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone), an anti-lipid-peroxidative compound: its chemical and biochemical characterizations.
Biochimica et biophysica acta.
1998 Sep; 1425(1):47-60. doi:
10.1016/s0304-4165(98)00050-6. [PMID: 9813237] - K Ogawa, M Futakuchi, M Hirose, P Boonyaphiphat, Y Mizoguchi, T Miki, T Shirai. Stage and organ dependent effects of 1-O-hexyl-2,3,5-trimethylhydroquinone, ascorbic acid derivatives, n-heptadecane-8-10-dione and phenylethyl isothiocyanate in a rat multiorgan carcinogenesis model.
International journal of cancer.
1998 Jun; 76(6):851-6. doi:
10.1002/(sici)1097-0215(19980610)76:6<851::aid-ijc14>3.0.co;2-5. [PMID: 9626352]