3-Ethyl-5-hydroxy-4,5-dimethyl-pyrrolin-2-one (BioDeep_00000179773)

   

human metabolite blood metabolite


代谢物信息卡片


3-ethyl-5-hydroxy-4,5-dimethyl-2,5-dihydro-1H-pyrrol-2-one

化学式: C8H13NO2 (155.0946238)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 96.88%

分子结构信息

SMILES: CCC1=C(C(NC1=O)(C)O)C
InChI: InChI=1S/C8H13NO2/c1-4-6-5(2)8(3,11)9-7(6)10/h11H,4H2,1-3H3,(H,9,10)



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Benjamin Warren, Jerome Sarris, Roger T Mulder, Julia J Rucklidge. Pyroluria: Fact or Fiction?. Journal of alternative and complementary medicine (New York, N.Y.). 2021 May; 27(5):407-415. doi: 10.1089/acm.2020.0151. [PMID: 33902305]
  • Yuan Zhou, Ruifeng Xue, Jinglin Wang, Haozhen Ren. Puerarin inhibits hepatocellular carcinoma invasion and metastasis through miR-21-mediated PTEN/AKT signaling to suppress the epithelial-mesenchymal transition. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 2020; 53(4):e8882. doi: 10.1590/1414-431x20198882. [PMID: 32294699]
  • Janusz Heitzman, Paweł Gosek, Wojciech Lechowicz, Ryszard Wardeński, Tomasz Stępień. Elevated hydroxylactam of hemopyrrole level in urine in perpetrators of extremely violent acts diagnosed with psychosis. Psychiatria polska. 2017 Jun; 51(3):413-423. doi: 10.12740/pp/67507. [PMID: 28866713]
  • Stephanie Fryar-Williams, Jörg E Strobel. Biomarkers of a five-domain translational substrate for schizophrenia and schizoaffective psychosis. Biomarker research. 2015; 3(?):3. doi: 10.1186/s40364-015-0028-1. [PMID: 25729574]
  • Woody R McGinnis, Tapan Audhya, William J Walsh, James A Jackson, John McLaren-Howard, Allen Lewis, Peter H Lauda, Douglas M Bibus, Frances Jurnak, Roman Lietha, Abram Hoffer. Discerning the Mauve factor, Part 2. Alternative therapies in health and medicine. 2008 May; 14(3):56-62. doi: NULL. [PMID: 18517107]
  • Woody R McGinnis, Tapan Audhya, William J Walsh, James A Jackson, John McLaren-Howard, Allen Lewis, Peter H Lauda, Douglas M Bibus, Frances Jurnak, Roman Lietha, Abram Hoffer. Discerning the Mauve Factor, Part 1. Alternative therapies in health and medicine. 2008 Mar; 14(2):40-50. doi: NULL. [PMID: 18383989]
  • J W van der Meer, R van de Kerkhof, G K The, G H Boers. [Hemopyrrollactamuria (HPU); from spots to pseudo-disease]. Nederlands tijdschrift voor geneeskunde. 2003 Sep; 147(36):1720-1. doi: NULL. [PMID: 14520795]
  • M G Cutler, D J Graham, M R Moore. The mauve factor of porphyria, 3-ethyl-5-hydroxy-4,5-dimethyl-delta-3-pyrroline-2-one: effects on behaviour of rats and mice. Pharmacology & toxicology. 1990 Jan; 66(1):66-8. doi: 10.1111/j.1600-0773.1990.tb00705.x. [PMID: 2308911]
  • A Gorchein. Urine concentration of 3-ethyl-5-hydroxy-4,5-dimethyl-delta 3-pyrrolin-2-one ('mauve factor') is not causally related to schizophrenia or to acute intermittent porphyria. Clinical science (London, England : 1979). 1980 Jun; 58(6):469-76. doi: 10.1042/cs0580469. [PMID: 7428279]
  • M R Moore, D J Graham. Monopyrroles in porphyria, psychosis and lead exposure. The International journal of biochemistry. 1980; 12(5-6):827-32. doi: 10.1016/0020-711x(80)90171-8. [PMID: 6893824]