Hexafluoroacetone (BioDeep_00000179740)

   

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


1,1,1,3,3,3-Hexafluoro-2-propanone

化学式: C3F6O (165.98533419999998)
中文名称: 无水六氟丙酮, 六氟丙酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(=O)(C(F)(F)F)C(F)(F)F
InChI: InChI=1S/C3F6O/c4-2(5,6)1(10)3(7,8)9

描述信息

同义名列表

14 个代谢物同义名

1,1,1,3,3,3-Hexafluoro-2-propanone; Hexafluoroacetone sesquihydrate; Hexafluoroacetone monohydrate; hexafluoroacetone trihydrate; Hexafluoroacetone dihydrate; Hexafluoroacetone hydrate; hexafluoropropan-2-one; Perfluoro-2-propanone; Hexafluoropropanone; Hexafluoroacetone; Perfluoroacetone; (CF3)2CO; 6FK; Hexafluoroacetone



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hae Jin Kim, Sung Han Ok, Sung Chul Bahn, Juno Jang, Sung Aeong Oh, Soon Ki Park, David Twell, Stephen Beungtae Ryu, Jeong Sheop Shin. Endoplasmic reticulum- and Golgi-localized phospholipase A2 plays critical roles in Arabidopsis pollen development and germination. The Plant cell. 2011 Jan; 23(1):94-110. doi: 10.1105/tpc.110.074799. [PMID: 21278126]
  • Carol J Belfiore, Raymond S H Yang, Laura S Chubb, Manupat Lohitnavy, Ornrat S Lohitnavy, Melvin E Andersen. Hepatic sequestration of chlordecone and hexafluoroacetone evaluated by pharmacokinetic modeling. Toxicology. 2007 May; 234(1-2):59-72. doi: 10.1016/j.tox.2007.02.002. [PMID: 17382449]
  • Shigeharu Myou, Xiangdong Zhu, Evan Boetticher, Yimin Qin, Saori Myo, Angelo Meliton, Anissa Lambertino, Nilda M Munoz, Kimm J Hamann, Alan R Leff. Regulation of adhesion of AML14.3D10 cells by surface clustering of beta2-integrin caused by ERK-independent activation of cPLA2. Immunology. 2002 Sep; 107(1):77-85. doi: 10.1046/j.1365-2567.2002.01486.x. [PMID: 12225365]
  • Darren Smart, Kent-Olov Jonsson, Séverine Vandevoorde, Didier M Lambert, Christopher J Fowler. 'Entourage' effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism. British journal of pharmacology. 2002 Jun; 136(3):452-8. doi: 10.1038/sj.bjp.0704732. [PMID: 12023948]
  • U Köster, D Mayer, H M Deger, W DeKant. Biotransformation of the aerosol propellant 1,1,1,2,3,3,3-heptafluoropropane (HFA-227): lack of protein binding of the metabolite hexafluoroacetone. Drug metabolism and disposition: the biological fate of chemicals. 1996 Aug; 24(8):906-10. doi: . [PMID: 8869827]
  • G L Kennedy. Toxicology of fluorine-containing monomers. Critical reviews in toxicology. 1990; 21(2):149-70. doi: 10.3109/10408449009089877. [PMID: 2083033]
  • P J Gillies, R W Rickard. Toxicokinetics of [14C]hexafluoroacetone in the rat. Toxicology and applied pharmacology. 1984 Mar; 73(1):23-9. doi: 10.1016/0041-008x(84)90048-6. [PMID: 6710515]
  • K P Lee, P J Gillies. Ultrastructural alterations in hexafluoroacetone-induced testicular atrophy in the rat. Experimental and molecular pathology. 1984 Feb; 40(1):29-37. doi: 10.1016/0014-4800(84)90063-7. [PMID: 6692903]
  • P J Gillies, K P Lee. Effects of hexafluoroacetone on testicular morphology and lipid metabolism in the rat. Toxicology and applied pharmacology. 1983 Apr; 68(2):188-97. doi: 10.1016/0041-008x(83)90003-0. [PMID: 6857659]