Hexadec-2-enal (BioDeep_00000179734)
human metabolite blood metabolite
代谢物信息卡片
化学式: C16H30O (238.2297)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 63.46%
分子结构信息
SMILES: CCCCCCCCCCCCCC=CC=O
InChI: InChI=1S/C16H30O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h14-16H,2-13H2,1H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Anja Lüth, Corinna Neuber, Burkhard Kleuser. Novel methods for the quantification of (2E)-hexadecenal by liquid chromatography with detection by either ESI QTOF tandem mass spectrometry or fluorescence measurement.
Analytica chimica acta.
2012 Apr; 722(?):70-9. doi:
10.1016/j.aca.2012.01.063. [PMID: 22444536] - Jerry E Chipuk, Gavin P McStay, Archana Bharti, Tomomi Kuwana, Christopher J Clarke, Leah J Siskind, Lina M Obeid, Douglas R Green. Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis.
Cell.
2012 Mar; 148(5):988-1000. doi:
10.1016/j.cell.2012.01.038. [PMID: 22385963] - Samy Selim, Manjula Sunkara, Abdelghaffar K Salous, Steve W Leung, Evgeny V Berdyshev, Alison Bailey, Charles L Campbell, Richard Charnigo, Andrew J Morris, Susan S Smyth. Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions.
Clinical science (London, England : 1979).
2011 Dec; 121(12):565-72. doi:
10.1042/cs20110236. [PMID: 21749329] - N Hagen, M Hans, D Hartmann, D Swandulla, G van Echten-Deckert. Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism.
Cell death and differentiation.
2011 Aug; 18(8):1356-65. doi:
10.1038/cdd.2011.7. [PMID: 21331079] - William B Rizzo. The role of fatty aldehyde dehydrogenase in epidermal structure and function.
Dermato-endocrinology.
2011 Apr; 3(2):91-9. doi:
10.4161/derm.3.2.14619. [PMID: 21695018] - Evgeny V Berdyshev, Irina Gorshkova, Peter Usatyuk, Satish Kalari, Yutong Zhao, Nigel J Pyne, Susan Pyne, Roger A Sabbadini, Joe G N Garcia, Viswanathan Natarajan. Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase.
PloS one.
2011 Jan; 6(1):e16571. doi:
10.1371/journal.pone.0016571. [PMID: 21304987] - Andrea Huwiler, Florence Bourquin, Nataliya Kotelevets, Oleksandr Pastukhov, Guido Capitani, Markus G Grütter, Uwe Zangemeister-Wittke. A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders.
PloS one.
2011; 6(8):e22436. doi:
10.1371/journal.pone.0022436. [PMID: 21829623] - Kacee Sims, Christopher A Haynes, Samuel Kelly, Jeremy C Allegood, Elaine Wang, Amin Momin, Martina Leipelt, Donna Reichart, Christopher K Glass, M Cameron Sullards, Alfred H Merrill. Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy.
The Journal of biological chemistry.
2010 Dec; 285(49):38568-79. doi:
10.1074/jbc.m110.170621. [PMID: 20876532] - Mariana Bertea, Markus F Rütti, Alaa Othman, Jaqueline Marti-Jaun, Martin Hersberger, Arnold von Eckardstein, Thorsten Hornemann. Deoxysphingoid bases as plasma markers in diabetes mellitus.
Lipids in health and disease.
2010 Aug; 9(?):84. doi:
10.1186/1476-511x-9-84. [PMID: 20712864] - Sarah T Pruett, Anatoliy Bushnev, Kerri Hagedorn, Madhura Adiga, Christopher A Haynes, M Cameron Sullards, Dennis C Liotta, Alfred H Merrill. Biodiversity of sphingoid bases ('sphingosines') and related amino alcohols.
Journal of lipid research.
2008 Aug; 49(8):1621-39. doi:
10.1194/jlr.r800012-jlr200. [PMID: 18499644] - Padmavathi Bandhuvula, Henrik Fyrst, Julie D Saba. A rapid fluorescence assay for sphingosine-1-phosphate lyase enzyme activity.
Journal of lipid research.
2007 Dec; 48(12):2769-78. doi:
10.1194/jlr.d700010-jlr200. [PMID: 17872591] - Viral V Brahmbhatt, Fong-Fu Hsu, Jeff L-F Kao, Erin C Frank, David A Ford. Novel carbonyl and nitrile products from reactive chlorinating species attack of lysosphingolipid.
Chemistry and physics of lipids.
2007 Feb; 145(2):72-84. doi:
10.1016/j.chemphyslip.2006.10.006. [PMID: 17126823] - Mika Ikeda, Akio Kihara, Yuki Kariya, Yong-Moon Lee, Yasuyuki Igarashi. Sphingolipid-to-glycerophospholipid conversion in SPL-null cells implies the existence of an alternative isozyme.
Biochemical and biophysical research communications.
2005 Apr; 329(2):474-9. doi:
10.1016/j.bbrc.2005.02.014. [PMID: 15737611] - . .
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