Hexachloronaphthalene (BioDeep_00000179732)
human metabolite blood metabolite
代谢物信息卡片
化学式: C10H2Cl6 (331.8287672)
中文名称: 卤蜡1014
谱图信息:
最多检出来源 Homo sapiens(blood) 50%
分子结构信息
SMILES: C1=CC(=C(C2=C1C(=C(C(=C2Cl)Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C10H2Cl6/c11-4-2-1-3-5(7(4)13)8(14)10(16)9(15)6(3)12/h1-2H
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Malwina Lisek, Tomasz Boczek, Joanna Stragierowicz, Julia Wawrzyniak, Feng Guo, Michał Klimczak, Anna Kilanowicz, Ludmila Zylinska. Hexachloronaphthalene (HxCN) impairs the dopamine pathway in an in vitro model of PC12 cells.
Chemosphere.
2022 Jan; 287(Pt 3):132284. doi:
10.1016/j.chemosphere.2021.132284
. [PMID: 34563782] - Malwina Lisek, Joanna Stragierowicz, Feng Guo, Philipp P Prosseda, Magdalena Wiktorska, Bozena Ferenc, Anna Kilanowicz, Ludmila Zylinska, Tomasz Boczek. Hexachloronaphthalene Induces Mitochondrial-Dependent Neurotoxicity via a Mechanism of Enhanced Production of Reactive Oxygen Species.
Oxidative medicine and cellular longevity.
2020; 2020(?):2479234. doi:
10.1155/2020/2479234
. [PMID: 32685088] - Joanna Stragierowicz, Elżbieta Bruchajzer, Adam Daragó, Marzenna Nasiadek, Anna Kilanowicz. Hexachloronaphthalene (HxCN) as a potential endocrine disruptor in female rats.
Environmental pollution (Barking, Essex : 1987).
2018 Dec; 243(Pt B):1026-1035. doi:
10.1016/j.envpol.2018.09.045
. [PMID: 30253293] - Michal Klimczak, Adam Darago, Elzbieta Bruchajzer, Katarzyna Domeradzka-Gajda, Maciej Stepnik, Katarzyna Kuzajska, Anna Kilanowicz. The effects of hexachloronaphthalene on selected parameters of heme biosynthesis and systemic toxicity in female wistar rats after 90-day oral exposure.
Environmental toxicology.
2018 Jun; 33(6):695-705. doi:
10.1002/tox.22558
. [PMID: 29663608] - Anna Kilanowicz, Adam Daragó, Małgorzata Skrzypińska-Gawrysiak. The effect of exposure route on the distribution and excretion of hexachloronaphthalene in rats.
International journal of occupational medicine and environmental health.
2012 Jun; 25(2):185-95. doi:
10.2478/s13382-012-0021-y
. [PMID: 22411071] - Anna Kilanowicz, Malgorzata Skrzypinska-Gawrysiak. Toxicity of hexachloronaphthalene (HxCN) and induction of CYP 1A in rats.
Ecotoxicology and environmental safety.
2010 Feb; 73(2):196-205. doi:
10.1016/j.ecoenv.2009.08.018
. [PMID: 19783048] - Daniel Carrizo, Joan O Grimalt. Rapid and simplified method for the analysis of polychloronaphthalene congener distributions in environmental and human samples by gas chromatography coupled to negative ion chemical ionization mass spectrometry.
Journal of chromatography. A.
2006 Jun; 1118(2):271-7. doi:
10.1016/j.chroma.2006.03.108
. [PMID: 16631763]