Colistin (BioDeep_00000017968)
human metabolite blood metabolite Chemicals and Drugs Antibiotics
代谢物信息卡片
N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-5-methylheptanamide
化学式: C52H98N16O13 (1154.7498898)
中文名称: 粘菌素
谱图信息:
最多检出来源 () 0%
Reviewed
Last reviewed on 2024-10-09.
Cite this Page
Colistin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/colistin (retrieved
2024-11-11) (BioDeep RN: BioDeep_00000017968). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CCC(C)CCCC(=O)NC(CCN)C(=O)NC(C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O)C(C)O
InChI: InChI=1S/C52H98N16O13/c1-9-29(6)11-10-12-40(71)59-32(13-19-53)47(76)68-42(31(8)70)52(81)64-35(16-22-56)44(73)63-37-18-24-58-51(80)41(30(7)69)67-48(77)36(17-23-57)61-43(72)33(14-20-54)62-49(78)38(25-27(2)3)66-50(79)39(26-28(4)5)65-45(74)34(15-21-55)60-46(37)75/h27-39,41-42,69-70H,9-26,53-57H2,1-8H3,(H,58,80)(H,59,71)(H,60,75)(H,61,72)(H,62,78)(H,63,73)(H,64,81)(H,65,74)(H,66,79)(H,67,77)(H,68,76)/t29?,30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,41+,42+/m1/s1
描述信息
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally. [PubChem]
A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07A - Intestinal antiinfectives > A07AA - Antibiotics
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01X - Other antibacterials > J01XB - Polymyxins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D011113 - Polymyxins
D000890 - Anti-Infective Agents > D023181 - Antimicrobial Cationic Peptides
同义名列表
10 个代谢物同义名
N-[(1S)-3-Amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-2,5,8,11,14,17,20-heptahydroxy-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-1,4,7,10,13,16,19-heptaazacyclotricosa-1,4,7,10,13,16,19-heptaen-21-yl]-C-hydroxycarbonimidoyl}propyl]-C-hydroxycarbonimidoyl}-2-hydroxypropyl]-C-hydroxycarbonimidoyl}propyl]-5-methylheptanimidate; N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide; Sulfate, colistin; Colistin sulfate; Polymyxin e; Colisticin; Coly-mycin; Colimycin; Totazina; colistin
数据库引用编号
8 个数据库交叉引用编号
- PubChem: 5311054
- HMDB: HMDB0014941
- ChEMBL: CHEMBL499783
- Wikipedia: Colistin
- MeSH: Colistin
- chemspider: 4470591
- CAS: 1066-17-7
- PMhub: MS000001495
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 64495 - Rhizopus arrhizus: 10.1128/AAC.00956-09
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Nalumon Thadtapong, Soraya Chaturongakul, Chanita Napaswad, Padungsri Dubbs, Sunhapas Soodvilai. Enhancing effect of natural adjuvant, panduratin A, on antibacterial activity of colistin against multidrug-resistant Acinetobacter baumannii.
Scientific reports.
2024 04; 14(1):9863. doi:
10.1038/s41598-024-60627-0. [PMID: 38684853] - Gabriela Kroneislová, Jan Závora, Vanda Gabriela Adámková, Anna Rýdlová, Václava Adámková. In vitro activity of antibiotics potentially effective against difficult-to-treat strains of Gram-negative rods: retrospective study.
Scientific reports.
2024 04; 14(1):8310. doi:
10.1038/s41598-024-59036-0. [PMID: 38594467] - Katherine R Hummels. mSphere of Influence: Celebrating exceptions to the rule of lipid A essentiality.
mSphere.
2024 Mar; 9(3):e0063323. doi:
10.1128/msphere.00633-23. [PMID: 38421175] - Ana Puljko, Ivan Barišić, Svjetlana Dekić Rozman, Stela Križanović, Ivana Babić, Marko Jelić, Ana Maravić, Nikolina Udiković-Kolić. Molecular epidemiology and mechanisms of carbapenem and colistin resistance in Klebsiella and other Enterobacterales from treated wastewater in Croatia.
Environment international.
2024 Mar; 185(?):108554. doi:
10.1016/j.envint.2024.108554. [PMID: 38479059] - Lingxian Yi, Kaiyang Yu, Guolong Gao, Rongmin Zhang, Luchao Lv, Daojin Yu, Jun Yang, Jian-Hua Liu. Successful spread of mcr-1-bearing IncX4 plasmids is associated with variant in replication protein of IncX4 plasmids.
Journal of global antimicrobial resistance.
2024 Mar; 36(?):365-370. doi:
10.1016/j.jgar.2024.01.012. [PMID: 38280721] - Collins Kigen, Angela Muraya, James Wachira, Lillian Musila. The first report of the mobile colistin resistance gene, mcr-10.1, in Kenya and a novel mutation in the phoQ gene (S244T) in a colistin-resistant Enterobacter cloacae clinical isolate.
Microbiology spectrum.
2024 Feb; 12(2):e0185523. doi:
10.1128/spectrum.01855-23. [PMID: 38230935] - Saranya Vijayakumar, Rayapadi G Swetha, Yamuna Devi Bakthavatchalam, Karthick Vasudevan, Baby Abirami Shankar, Agilandeeswari Kirubananthan, Kamini Walia, Sudha Ramaiah, Indranil Biswas, Balaji Veeraraghavan, Anand Anbarasu. Genomic investigation unveils colistin resistance mechanism in carbapenem-resistant Acinetobacter baumannii clinical isolates.
Microbiology spectrum.
2024 Feb; 12(2):e0251123. doi:
10.1128/spectrum.02511-23. [PMID: 38214512] - Massimiliano Lucidi, Francesco Imperi, Irene Artuso, Giulia Capecchi, Cinzia Spagnoli, Daniela Visaggio, Giordano Rampioni, Livia Leoni, Paolo Visca. Phage-mediated colistin resistance in Acinetobacter baumannii.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
2024 Jan; 73(?):101061. doi:
10.1016/j.drup.2024.101061. [PMID: 38301486] - Albebson L Lim, Bailey W Miller, Zhenjian Lin, Mark A Fisher, Louis R Barrows, Margo G Haygood, Eric W Schmidt. Resistance mechanisms for Gram-negative bacteria-specific lipopeptides, turnercyclamycins, differ from that of colistin.
Microbiology spectrum.
2023 Dec; 11(6):e0230623. doi:
10.1128/spectrum.02306-23. [PMID: 37882570] - M Cem Şirin, Yasemin Cezaroğlu, E Sesli Çetin, Buket Arıdoğan, Diğdem Trak, Yasin Arslan. Antibacterial and antibiofilm efficacy of colistin & meropenem conjugated silver nanoparticles against Escherichia coli and Klebsiella pneumoniae.
Journal of basic microbiology.
2023 Dec; 63(12):1397-1411. doi:
10.1002/jobm.202300440. [PMID: 37821405] - Lujie Liang, Lan-Lan Zhong, Lin Wang, Dianrong Zhou, Yaxin Li, Jiachen Li, Yong Chen, Wanfei Liang, Wenjing Wei, Chenchen Zhang, Hui Zhao, Lingxuan Lyu, Nicole Stoesser, Yohei Doi, Fang Bai, Siyuan Feng, Guo-Bao Tian. A new variant of the colistin resistance gene MCR-1 with co-resistance to β-lactam antibiotics reveals a potential novel antimicrobial peptide.
PLoS biology.
2023 Dec; 21(12):e3002433. doi:
10.1371/journal.pbio.3002433. [PMID: 38091366] - Suyeon Park, Jihyun Choi, Dongwoo Shin, Ki Tae Kwon, Si-Ho Kim, Yu Mi Wi, Kwan Soo Ko. Conversion to colistin susceptibility by tigecycline exposure in colistin-resistant Klebsiella pneumoniae and its implications to combination therapy.
International journal of antimicrobial agents.
2023 Oct; ?(?):107017. doi:
10.1016/j.ijantimicag.2023.107017. [PMID: 37884228] - Yan Liu, Yue Wang, Jingchun Kong, Xianguo Jiang, Yijia Han, Luozhu Feng, Yao Sun, Lijiang Chen, Tieli Zhou. An effective antimicrobial strategy of colistin combined with the Chinese herbal medicine shikonin against colistin-resistant Escherichia coli.
Microbiology spectrum.
2023 Oct; ?(?):e0145923. doi:
10.1128/spectrum.01459-23. [PMID: 37800902] - Chonnikan Hanpaibool, Puey Ounjai, Sirilata Yotphan, Adrian J Mulholland, James Spencer, Natharin Ngamwongsatit, Thanyada Rungrotmongkol. Enhancement by pyrazolones of colistin efficacy against mcr-1-expressing E. coli: an in silico and in vitro investigation.
Journal of computer-aided molecular design.
2023 10; 37(10):479-489. doi:
10.1007/s10822-023-00519-z. [PMID: 37488458] - Joana Pires, Ricardo Santos, Sílvia Monteiro. Antibiotic resistance genes in bacteriophages from wastewater treatment plant and hospital wastewaters.
The Science of the total environment.
2023 Sep; 892(?):164708. doi:
10.1016/j.scitotenv.2023.164708. [PMID: 37315610] - Chenghao Wang, Biao Tang, Jiusheng Wu, Xi Jin, Shuwen Ke, Hua Yang, Yuehuan Liu. Detection of mcr-1-harbouring Escherichia coli by quantum dot labelling of synthetic small peptides mimicking lipopolysaccharide receptors.
International journal of antimicrobial agents.
2023 Sep; 62(3):106898. doi:
10.1016/j.ijantimicag.2023.106898. [PMID: 37343806] - Bára Křížkovská, Lan Hoang, Daniela Brdová, Kristýna Klementová, Nikoletta Szemerédi, Anna Loučková, Olga Kronusová, Gabriella Spengler, Petr Kaštánek, Jana Hajšlová, Jitka Viktorová, Jan Lipov. Modulation of the bacterial virulence and resistance by well-known European medicinal herbs.
Journal of ethnopharmacology.
2023 Aug; 312(?):116484. doi:
10.1016/j.jep.2023.116484. [PMID: 37044231] - Jialiang Mai, Zhuwei Liang, Zhile Xiong, Chao Zhang, Hao Cai, Shuwen Yao, Xiantang Chen, Bingshao Liang, Fei Gao, Zhuohong Huang, Fangjun Lan, Shuyan Liu, Zhenwen Zhou. Fecal carriage and molecular epidemiology of mcr-1-harboring Escherichia coli from children in southern China.
Journal of infection and public health.
2023 Jul; 16(7):1057-1063. doi:
10.1016/j.jiph.2023.05.005. [PMID: 37196369] - Michio Kurosu, Katsuhiko Mitachi, Edward V Pershing, Bruce D Horowitz, Eric A Wachter, John W Lacey, Yinduo Ji, Dominic J Rodrigues. Antibacterial effect of rose bengal against colistin-resistant gram-negative bacteria.
The Journal of antibiotics.
2023 07; 76(7):416-424. doi:
10.1038/s41429-023-00622-1. [PMID: 37076631] - Niamh Cahill, Brigid Hooban, Kelly Fitzhenry, Aoife Joyce, Louise O'Connor, Georgios Miliotis, Francesca McDonagh, Liam Burke, Alexandra Chueiri, Maeve Louise Farrell, James E Bray, Niall Delappe, Wendy Brennan, Deirdre Prendergast, Montserrat Gutierrez, Catherine Burgess, Martin Cormican, Dearbháile Morris. First reported detection of the mobile colistin resistance genes, mcr-8 and mcr-9, in the Irish environment.
The Science of the total environment.
2023 Jun; 876(?):162649. doi:
10.1016/j.scitotenv.2023.162649. [PMID: 36906027] - Huangdu Hu, Qiucheng Shi, Ping Zhang, Jingjing Quan, Xinhong Han, Dongdong Zhao, Huichuan Zhang, Qian Wang, Yan Jiang, Yunsong Yu. Prevalence and molecular characteristics of colistin-resistant isolates among clinically isolated carbapenem-resistant Klebsiella pneumoniae in China.
International journal of antimicrobial agents.
2023 Jun; ?(?):106873. doi:
10.1016/j.ijantimicag.2023.106873. [PMID: 37276893] - Sun Ju Kim, Jeongwoo Jo, Kwan Soo Ko. Lipid A modification-induced colistin-resistant Klebsiella variicola from healthy adults.
Journal of medical microbiology.
2023 Jun; 72(6):. doi:
10.1099/jmm.0.001680. [PMID: 37261959] - Anju Yadav, Payam Kelich, Nathaniel Kallmyer, Nigel F Reuel, Lela Vuković. Characterizing the Interactions of Cell-Membrane-Disrupting Peptides with Lipid-Functionalized Single-Walled Carbon Nanotubes.
ACS applied materials & interfaces.
2023 May; 15(20):24084-24096. doi:
10.1021/acsami.3c01217. [PMID: 37184257] - Caroline Willis, Frieda Jørgensen, Shaun Cawthraw, Heather Aird, Sandra Lai, Michelle Kesby, Marie Chattaway, Ioana Lock, Emiline Quill, Gabriela Raykova. A survey of Salmonella, Escherichia coli, and antimicrobial resistance in frozen, part-cooked, breaded, or battered chicken products on retail sale in the UK.
Journal of applied microbiology.
2023 May; 134(5):. doi:
10.1093/jambio/lxad093. [PMID: 37133419] - Qiwei Chen, Heng Quan, Yongfeng Yu, Donghui Liu, Caiyu Li, Yuefeng Chu, Xiaowei Gong. EptA of Riemerella anatipestifer mediates phenotypes involved in colistin resistance and virulence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2023 05; 37(5):e22928. doi:
10.1096/fj.202300215r. [PMID: 37071453] - Tianshi Xiao, Xiaolin Zhu, Wenhui Wang, Xuchen Jia, Changmei Guo, Xue Wang, Zhihui Hao. A novel lytic bacteriophage against colistin-resistant Escherichia coli isolated from different animals.
Virus research.
2023 05; 329(?):199090. doi:
10.1016/j.virusres.2023.199090. [PMID: 36944413] - Lindsey A Carfrae, Kenneth Rachwalski, Shawn French, Rodion Gordzevich, Laura Seidel, Caressa N Tsai, Megan M Tu, Craig R MacNair, Olga G Ovchinnikova, Bradley R Clarke, Chris Whitfield, Eric D Brown. Inhibiting fatty acid synthesis overcomes colistin resistance.
Nature microbiology.
2023 May; ?(?):. doi:
10.1038/s41564-023-01369-z. [PMID: 37127701] - Di Wang, Huiyun Zou, Ling Zhao, Qi Li, Min Meng, Xuewen Li, Björn Berglund. High prevalence of Escherichia coli co-harboring conjugative plasmids with colistin- and carbapenem resistance genes in a wastewater treatment plant in China.
International journal of hygiene and environmental health.
2023 05; 250(?):114159. doi:
10.1016/j.ijheh.2023.114159. [PMID: 36989999] - Renate Frantz, Konrad Gwozdzinski, Nicolas Gisch, Swapnil Prakash Doijad, Martina Hudel, Maria Wille, Mobarak Abu Mraheil, Dominik Schwudke, Can Imirzalioglu, Linda Falgenhauer, Michael Ehrmann, Trinad Chakraborty. A Single Residue within the MCR-1 Protein Confers Anticipatory Resilience.
Microbiology spectrum.
2023 Apr; ?(?):e0359222. doi:
10.1128/spectrum.03592-22. [PMID: 37071007] - Gerald Larrouy-Maumus, Laurent Dortet, Ilka D Nix, Thomas Maier, Boris Oberheitmann, Katrin Sparbier, Markus Kostrzewa. Two-site study on performances of a commercially available MALDI-TOF MS-based assay for the detection of colistin resistance in Escherichia coli.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2023 Mar; ?(?):. doi:
10.1007/s10096-023-04587-9. [PMID: 36973378] - Masafumi Sakuma, Masahito Hashimoto, Kanako Nishi, Mari Tohya, Tomomi Hishinuma, Masahiro Shimojima, Tatsuya Tada, Teruo Kirikae. Emergence of colistin-resistant Acinetobacter modestus harbouring the intrinsic phosphoethanolamine transferase EptA.
Journal of global antimicrobial resistance.
2023 Mar; 33(?):101-108. doi:
10.1016/j.jgar.2023.02.023. [PMID: 36906175] - Claudia Vairo, Maria Villar Vidal, Rosa Maria Hernandez, Manoli Igartua, Silvia Villullas. Colistin- and Amikacin-loaded lipid-based drug delivery systems for resistant gram-negative lung and wound bacterial infections.
International journal of pharmaceutics.
2023 Feb; ?(?):122739. doi:
10.1016/j.ijpharm.2023.122739. [PMID: 36801363] - José Avendaño-Ortiz, Manuel Ponce-Alonso, Emilio Llanos-González, Hugo Barragán-Prada, Raquel Barbero-Herranz, Roberto Lozano-Rodríguez, Francesc J Márquez-Garrido, José María Hernández-Pérez, María-Isabel Morosini, Rafael Cantón, Rosa Del Campo, Eduardo López-Collazo. The Impact of Colistin Resistance on the Activation of Innate Immunity by Lipopolysaccharide Modification.
Infection and immunity.
2023 Feb; 91(2):e0001223. doi:
10.1128/iai.00012-23. [PMID: 36722977] - Xiao-Die Cui, Jun-Kai Zhang, Ya-Wei Sun, Feng-Bin Yan, Jin-Feng Zhao, Dan-Dan He, Yu-Shan Pan, Li Yuan, Ya-Jun Zhai, Gong-Zheng Hu. Synergistic antibacterial activity of baicalin and EDTA in combination with colistin against colistin-resistant Salmonella.
Poultry science.
2023 Feb; 102(2):102346. doi:
10.1016/j.psj.2022.102346. [PMID: 36493546] - Mohamed Rhouma, Jean-Yves Madec, Ramanan Laxminarayan. Colistin: from the shadows to a One Health approach for addressing antimicrobial resistance.
International journal of antimicrobial agents.
2023 Feb; 61(2):106713. doi:
10.1016/j.ijantimicag.2023.106713. [PMID: 36640846] - Ximin Zeng, Atsushi Hinenoya, Ziqiang Guan, Fuzhou Xu, Jun Lin. Critical role of the RpoE stress response pathway in polymyxin resistance of Escherichia coli.
The Journal of antimicrobial chemotherapy.
2023 Jan; ?(?):. doi:
10.1093/jac/dkad003. [PMID: 36658759] - Swapnil Prakash Doijad, Nicolas Gisch, Renate Frantz, Bajarang Vasant Kumbhar, Jane Falgenhauer, Can Imirzalioglu, Linda Falgenhauer, Alexander Mischnik, Jan Rupp, Michael Behnke, Michael Buhl, Simone Eisenbeis, Petra Gastmeier, Hanna Gölz, Georg Alexander Häcker, Nadja Käding, Winfried V Kern, Axel Kola, Evelyn Kramme, Silke Peter, Anna M Rohde, Harald Seifert, Evelina Tacconelli, Maria J G T Vehreschild, Sarah V Walker, Janine Zweigner, Dominik Schwudke, Trinad Chakraborty. Resolving colistin resistance and heteroresistance in Enterobacter species.
Nature communications.
2023 Jan; 14(1):140. doi:
10.1038/s41467-022-35717-0. [PMID: 36627272] - Ahmed Gaballa, Martin Wiedmann, Laura M Carroll. More than mcr: canonical plasmid- and transposon-encoded mobilized colistin resistance genes represent a subset of phosphoethanolamine transferases.
Frontiers in cellular and infection microbiology.
2023; 13(?):1060519. doi:
10.3389/fcimb.2023.1060519. [PMID: 37360531] - Xiaoyang Ju, Siheng Wang, Xuemei Yang, Weihua Han, Chang Cai, Yuchen Wu, Congcong Liu, Jiao Qian, Xiaofei Zhao, Xiang Qian, Qiaoling Sun, Rong Zhang, Gongxiang Chen. Epidemiology and Molecular Characteristics of mcr-9 in Citrobacter spp. from Healthy Individuals and Patients in China.
Microbiology spectrum.
2022 12; 10(6):e0134622. doi:
10.1128/spectrum.01346-22. [PMID: 36374095] - Pegah Kananizadeh, Tatsuya Tada, Satoshi Oshiro, Tomomi Hishinuma, Mari Tohya, Yuki Uehara, Yumi Kumagai, Isao Nagaoka, Kanako Nishi, Masahito Hashimoto, Shin Watanabe, Teruo Kirikae. Modified Drug-Susceptibility Testing and Screening Culture Agar for Colistin-Susceptible Enterobacteriaceae Isolates Harboring a Mobilized Colistin Resistance Gene mcr-9.
Journal of clinical microbiology.
2022 12; 60(12):e0139922. doi:
10.1128/jcm.01399-22. [PMID: 36445156] - Anthony Harrington, Van Vo, Katerina Papp, Richard L Tillett, Ching-Lan Chang, Hayley Baker, Shirley Shen, Amei Amei, Cassius Lockett, Daniel Gerrity, Edwin C Oh. Urban monitoring of antimicrobial resistance during a COVID-19 surge through wastewater surveillance.
The Science of the total environment.
2022 Dec; 853(?):158577. doi:
10.1016/j.scitotenv.2022.158577. [PMID: 36087661] - Siyuan Feng, Wanfei Liang, Jiachen Li, Yong Chen, Dianrong Zhou, Lujie Liang, Daixi Lin, Yaxin Li, Hui Zhao, Huihui Du, Min Dai, Li-Na Qin, Fan Bai, Yohei Doi, Lan-Lan Zhong, Guo-Bao Tian. MCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria.
Emerging microbes & infections.
2022 Dec; 11(1):1236-1249. doi:
10.1080/22221751.2022.2065934. [PMID: 35437117] - Lucile Pantel, François Guérin, Marine Serri, François Gravey, Jessica Houard, Kelly Maurent, Marie Attwood, Alan Noel, Alasdair MacGowan, Emilie Racine, Vincent Cattoir, Maxime Gualtieri. Exploring Cluster-Dependent Antibacterial Activities and Resistance Pathways of NOSO-502 and Colistin against Enterobacter cloacae Complex Species.
Antimicrobial agents and chemotherapy.
2022 11; 66(11):e0077622. doi:
10.1128/aac.00776-22. [PMID: 36200761] - Peiyao Jia, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Wei Yu, Rui Li, Xue Li, Mei Kang, Yingchun Xu, Qiwen Yang. Emergence of a Novel NDM-5-Producing Sequence Type 4523 Klebsiella pneumoniae Strain Causing Bloodstream Infection in China.
Microbiology spectrum.
2022 10; 10(5):e0084222. doi:
10.1128/spectrum.00842-22. [PMID: 35993711] - Polly Soo-Xi Yap, Wan-Hee Cheng, Sook-Keng Chang, Swee-Hua Erin Lim, Kok-Song Lai. MgrB Mutations and Altered Cell Permeability in Colistin Resistance in Klebsiella pneumoniae.
Cells.
2022 09; 11(19):. doi:
10.3390/cells11192995. [PMID: 36230959] - Jiangang Ma, Wei Zhou, Jing Wu, Xiaofeng Liu, Jiahui Lin, Xiaofeng Ji, Hui Lin, Jianmei Wang, Han Jiang, Qianjin Zhou, Guoping Zhao, Hua Yang, Biao Tang. Large-Scale Studies on Antimicrobial Resistance and Molecular Characterization of Escherichia coli from Food Animals in Developed Areas of Eastern China.
Microbiology spectrum.
2022 08; 10(4):e0201522. doi:
10.1128/spectrum.02015-22. [PMID: 35950758] - Agnès Perrin-Guyomard, Sophie A Granier, Jannice Schau Slettemeås, Muna Anjum, Luke Randall, Manal AbuOun, Natalie Pauly, Alexandra Irrgang, Jens Andre Hammerl, Jette Sejer Kjeldgaard, Anette Hammerum, Alessia Franco, Magdalena Skarżyńska, Ewelina Kamińska, Dariusz Wasyl, Cindy Dierikx, Stefan Börjesson, Yvon Geurts, Marisa Haenni, Kees Veldman. Multicentre evaluation of a selective isolation protocol for detection of mcr-positive E. coli and Salmonella spp. in food-producing animals and meat.
Letters in applied microbiology.
2022 Aug; 75(2):224-233. doi:
10.1111/lam.13717. [PMID: 35388505] - Sukrit Srisakul, Dhammika Leshan Wannigama, Paul G Higgins, Cameron Hurst, Shuichi Abe, Parichart Hongsing, Thammakorn Saethang, Sirirat Luk-In, Tingting Liao, Naris Kueakulpattana, Aye Mya Sithu Shein, Lin Gan, Rosalyn Kupwiwat, Chanikan Tanasatitchai, Pattama Wapeesittipan, Phatthranit Phattharapornjaroen, Vishnu Nayak Badavath, Asada Leelahavanichkul, Tanittha Chatsuwan. Overcoming addition of phosphoethanolamine to lipid A mediated colistin resistance in Acinetobacter baumannii clinical isolates with colistin-sulbactam combination therapy.
Scientific reports.
2022 07; 12(1):11390. doi:
10.1038/s41598-022-15386-1. [PMID: 35794134] - Mingxing Sui, Nanxin Zheng, Da Xu, Yuhong Li, Yanhua Li, Shijun Pu, Meili Ji, Suxia Yang, Yutong Chen, Juan Huang, Youhua Zhu, Hanlan Lu, Li Zeng. Colistin sulfate for decontamination of preservation fluid in kidney transplantation to decrease the incidence of donor-derived infections caused by multidrug-resistant Gram-negative bacteria.
Transplant infectious disease : an official journal of the Transplantation Society.
2022 Jun; 24(3):e13820. doi:
10.1111/tid.13820. [PMID: 35279926] - Khalid M Badr El-Din, Mahmoud A Abdelmajed, Mahmoud A Omar, Tamer Z Attia. Salvage parenteral antibiotics for multidrug-resistant (MDR) Gram-negative bacteria; a fluorescamine-based technique for ultrasensitive spectrofluorimetric measurement of Polymyxins; human plasma application.
Luminescence : the journal of biological and chemical luminescence.
2022 Jun; 37(6):971-979. doi:
10.1002/bio.4245. [PMID: 35393741] - Biao Tang, Jiang Chang, Yi Luo, Han Jiang, Canying Liu, Xingning Xiao, Xiaofeng Ji, Hua Yang. Prevalence and characteristics of the mcr-1 gene in retail meat samples in Zhejiang Province, China.
Journal of microbiology (Seoul, Korea).
2022 Jun; 60(6):610-619. doi:
10.1007/s12275-022-1597-y. [PMID: 35362896] - Sharifzadeh Meysam, Zahra Khosravi, Roshanak Rashti, Mostafa Qorbani, Farahnak Assadi, Alireza Hayatshahi, Tanzifi Parin, Toktam Faghihi. Colistin induced acute kidney injury in critically ill children: a prospective study utilizing RIFLE criteria.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences.
2022 Jun; 30(1):11-15. doi:
10.1007/s40199-021-00421-9. [PMID: 34807396] - Aikaterini Gkoufa, Tomás Sou, Ilias Karaiskos, Christina Routsi, Yu-Wei Lin, Mina Psichogiou, Spyros Zakynthinos, Helen Giamarellou, Jian Li, Lena E Friberg. Pulmonary and systemic pharmacokinetics of colistin methanesulfonate (CMS) and formed colistin following nebulisation of CMS among patients with ventilator-associated pneumonia.
International journal of antimicrobial agents.
2022 Jun; 59(6):106588. doi:
10.1016/j.ijantimicag.2022.106588. [PMID: 35405269] - Hyojik Yang, Richard D Smith, Courtney E Chandler, J Kristie Johnson, Shelley N Jackson, Amina S Woods, Alison J Scott, David R Goodlett, Robert K Ernst. Lipid A Structural Determination from a Single Colony.
Analytical chemistry.
2022 05; 94(21):7460-7465. doi:
10.1021/acs.analchem.1c05394. [PMID: 35576511] - Kalliopi Papavasileiou, Apostolia Tsiasioti, Paraskevas D Tzanavaras, Constantinos K Zacharis. HPLC Determination of Colistin in Human Urine Using Alkaline Mobile Phase Combined with Post-Column Derivatization: Validation Using Accuracy Profiles.
Molecules (Basel, Switzerland).
2022 May; 27(11):. doi:
10.3390/molecules27113489. [PMID: 35684427] - Ilanila Ilangumaran Ponmalar, Jitendriya Swain, Jaydeep K Basu. Escherichia coli response to subinhibitory concentrations of colistin: insights from a study of membrane dynamics and morphology.
Biomaterials science.
2022 May; 10(10):2609-2617. doi:
10.1039/d2bm00037g. [PMID: 35411890] - Mahtabalsadat Mirjalili, Ehsan Mirzaei, Afsaneh Vazin. Pharmacological agents for the prevention of colistin-induced nephrotoxicity.
European journal of medical research.
2022 May; 27(1):64. doi:
10.1186/s40001-022-00689-w. [PMID: 35525994] - Maleeha Urooj, Rooh Ullah, Sakhawat Ali, Aisha Mohyuddin, Hira Mehboob Mirza, Rani Faryal. Elucidation of molecular mechanism for colistin resistance among Gram-negative isolates from tertiary care hospitals.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2022 May; 28(5):602-609. doi:
10.1016/j.jiac.2022.01.002. [PMID: 35058128] - Javier F Garcia, Marcela Nastro, Laura Dabos, Josefina Campos, German Traglia, Cecilia Vera Ocampo, Angela Famiglietti, Carlos H Rodriguez, Carlos A Vay. Molecular and Phenotypic Characterization of a Multidrug-Resistant Escherichia coli Coproducing OXA-232 and MCR-1.1 in Argentina.
Microbial drug resistance (Larchmont, N.Y.).
2022 May; 28(5):511-516. doi:
10.1089/mdr.2021.0167. [PMID: 35275771] - Pablo Acín, Sonia Luque, Luisa Sorli, Santiago Grau. Therapeutic drug monitoring of colistin in plasma and cerebrospinal fluid in meningoventriculitis caused by a carbapenem-resistant Enterobacter cloacae.
Enfermedades infecciosas y microbiologia clinica (English ed.).
2022 May; 40(5):277-278. doi:
10.1016/j.eimce.2021.02.011. [PMID: 35577447] - Fatih Turan Ayilgan, Mehmet Salih Sevdi, Serdar Demirgan, Funda Gumus Ozcan, Kerem Erkalp, Aysin Selcan. Evaluation of Acute Renal Failure After Acinetobacter Baumannii-related Ventilator-associated Event: Routine Data Base Study.
Iranian journal of kidney diseases.
2022 May; 16(3):171-178. doi:
NULL. [PMID: 35714211] - Shengnan Xie, Li Li, Baihe Zhan, Xue Shen, Xuming Deng, Wenxi Tan, Tianqi Fang. Pogostone Enhances the Antibacterial Activity of Colistin against MCR-1-Positive Bacteria by Inhibiting the Biological Function of MCR-1.
Molecules (Basel, Switzerland).
2022 Apr; 27(9):. doi:
10.3390/molecules27092819. [PMID: 35566163] - Xia Xiao, Fuxin Zeng, Ruichao Li, Yuan Liu, Zhiqiang Wang. Subinhibitory Concentration of Colistin Promotes the Conjugation Frequencies of Mcr-1- and blaNDM-5-Positive Plasmids.
Microbiology spectrum.
2022 04; 10(2):e0216021. doi:
10.1128/spectrum.02160-21. [PMID: 35230128] - Andrew S Bray, Richard D Smith, Andrew W Hudson, Giovanna E Hernandez, Taylor M Young, Hannah E George, Robert K Ernst, M Ammar Zafar. MgrB-Dependent Colistin Resistance in Klebsiella pneumoniae Is Associated with an Increase in Host-to-Host Transmission.
mBio.
2022 04; 13(2):e0359521. doi:
10.1128/mbio.03595-21. [PMID: 35311534] - Sheng-Huei Wang, Kuang-Yao Yang, Chau-Chyun Sheu, Wei-Cheng Chen, Ming-Cheng Chan, Jia-Yih Feng, Chia-Min Chen, Biing-Ru Wu, Zhe-Rong Zheng, Yu-Ching Chou, Chung-Kan Peng. The necessity of a loading dose when prescribing intravenous colistin in critically ill patients with CRGNB-associated pneumonia: a multi-center observational study.
Critical care (London, England).
2022 04; 26(1):91. doi:
10.1186/s13054-022-03947-9. [PMID: 35379303] - Matthieu Boisson, Adrien Bouglé, Candela Sole-Lleonart, Jayesh Dhanani, Kostoula Arvaniti, Jordi Rello, Jean-Jacques Rouby, Olivier Mimoz. Nebulized Antibiotics for Healthcare- and Ventilator-Associated Pneumonia.
Seminars in respiratory and critical care medicine.
2022 04; 43(2):255-270. doi:
10.1055/s-0041-1740340. [PMID: 35042259] - Mousumi Ray, Ashwini Manjunath, Prakash M Halami. Prevalence of polymyxin resistance through the food chain, the global crisis.
The Journal of antibiotics.
2022 04; 75(4):185-198. doi:
10.1038/s41429-022-00502-0. [PMID: 35079146] - Nichakorn Worakajit, Natechanok Thipboonchoo, Soraya Chaturongakul, Promsuk Jutabha, Virawudh Soontornniyomkij, Patoomratana Tuchinda, Sunhapas Soodvilai. Nephroprotective potential of Panduratin A against colistin-induced renal injury via attenuating mitochondrial dysfunction and cell apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Apr; 148(?):112732. doi:
10.1016/j.biopha.2022.112732. [PMID: 35217281] - Tomoki Komeda, Shovita Shrestha, Jatan B Sherchan, Mari Tohya, Tomomi Hishinuma, Jeevan B Sherchand, Tatsuya Tada, Teruo Kirikae. Emergence of a highly colistin-resistant Aeromonas jandaei clinical isolate harbouring four genes encoding phosphoethanolamine transferases in Nepal.
International journal of antimicrobial agents.
2022 Apr; 59(4):106544. doi:
10.1016/j.ijantimicag.2022.106544. [PMID: 35134503] - Bence Mogyoródi, András B Csékó, Csaba Hermann, János Gál, Zsolt D Iványi. Ceftolozane/tazobactam versus colistin in the treatment of ventilator-associated pneumonia due to extensively drug-resistant Pseudomonas aeruginosa.
Scientific reports.
2022 03; 12(1):4455. doi:
10.1038/s41598-022-08307-9. [PMID: 35292686] - Nguyen Phuoc Long, Jung-Hwa Oh, Se-Myo Park, Nguyen Thi Hai Yen, Nguyen Ky Phat, Yong-Soon Cho, Hyung Min Kim, Seokjoo Yoon, Jae-Gook Shin, Dong Hyun Kim. Delineation of the molecular mechanisms underlying Colistin-mediated toxicity using metabolomic and transcriptomic analyses.
Toxicology and applied pharmacology.
2022 03; 439(?):115928. doi:
10.1016/j.taap.2022.115928. [PMID: 35189178] - Adrian Gorecki, Marcin Musialowski, Mikolaj Wolacewicz, Przemyslaw Decewicz, Catarina Ferreira, Dana Vejmelkova, Malgorzata Grzesiuk, Celia M Manaia, Jan Bartacek, Lukasz Dziewit. Development and validation of novel PCR primers for identification of plasmid-mediated colistin resistance (mcr) genes in various environmental settings.
Journal of hazardous materials.
2022 03; 425(?):127936. doi:
10.1016/j.jhazmat.2021.127936. [PMID: 34883371] - Burak Dumludag, Mehmet Kursat Derici, Osman Sutcuoglu, Betul Ogut, Ozge Tugce Pasaoglu, Ipek Isık Gonul, Ulver Derici. Role of silymarin (Silybum marianum) in the prevention of colistin-induced acute nephrotoxicity in rats.
Drug and chemical toxicology.
2022 Mar; 45(2):568-575. doi:
10.1080/01480545.2020.1733003. [PMID: 32174194] - Thamer A Almangour, Ahmad Aljabri, Mohammed Al Musawa, Abdullah Almohaizeie, Sara Almuhisen, Nader Damfu, Awaly Alfozan, Basem M Alraddadi, Majda Alattas, Mohammed Qutub, Abrar F Alhameed, Malik Khuwaja, Ahlam Alghamdi, Khalifa M Binkhamis, Wafa Alfahad, Fatimah S AlShahrani. Ceftolozane-tazobactam vs. colistin for the treatment of infections due to multidrug-resistant Pseudomonas aeruginosa: a multicentre cohort study.
Journal of global antimicrobial resistance.
2022 03; 28(?):288-294. doi:
10.1016/j.jgar.2022.01.023. [PMID: 35121161] - Richard D Smith, Christi L McElheny, Jerilyn R Izac, Francesca M Gardner, Courtney E Chandler, David R Goodlett, Yohei Doi, J Kristie Johnson, Robert K Ernst. A Novel Lipid-Based MALDI-TOF Assay for the Rapid Detection of Colistin-Resistant Enterobacter Species.
Microbiology spectrum.
2022 02; 10(1):e0144521. doi:
10.1128/spectrum.01445-21. [PMID: 35107363] - Bich Vu Thi Ngoc, Thanh Le Viet, Mai Nguyen Thi Tuyet, Thuong Nguyen Thi Hong, Diep Nguyen Thi Ngoc, Duyet Le Van, Loan Chu Thi, Hoang Tran Huy, John Penders, Heiman Wertheim, H Rogier van Doorn. Characterization of Genetic Elements Carrying mcr-1 Gene in Escherichia coli from the Community and Hospital Settings in Vietnam.
Microbiology spectrum.
2022 02; 10(1):e0135621. doi:
10.1128/spectrum.01356-21. [PMID: 35138158] - Kerrie L May. Drown Them in Their Own Garbage: a New Strategy To Reverse Polymyxin Resistance?.
Journal of bacteriology.
2022 02; 204(2):e0057421. doi:
10.1128/jb.00574-21. [PMID: 34843378] - Suthathip Trongjit, Pornchalit Assavacheep, Sukuma Samngamnim, Tran Hoang My, Vo Thi Tra An, Shabbir Simjee, Rungtip Chuanchuen. Plasmid-mediated colistin resistance and ESBL production in Escherichia coli from clinically healthy and sick pigs.
Scientific reports.
2022 02; 12(1):2466. doi:
10.1038/s41598-022-06415-0. [PMID: 35165337] - Andrew N Murtha, Misha I Kazi, Richard D Schargel, Trevor Cross, Conrad Fihn, Vincent Cattoir, Erin E Carlson, Joseph M Boll, Tobias Dörr. High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications.
PLoS pathogens.
2022 02; 18(2):e1010307. doi:
10.1371/journal.ppat.1010307. [PMID: 35130322] - Sue C Nang, Mengyao Li, Marina Harper, Eric Mandela, Phillip J Bergen, Jean-Marc Rolain, Yan Zhu, Tony Velkov, Jian Li. Polymyxin causes cell envelope remodelling and stress responses in mcr-1-harbouring Escherichia coli.
International journal of antimicrobial agents.
2022 Feb; 59(2):106505. doi:
10.1016/j.ijantimicag.2021.106505. [PMID: 34954369] - Komal Nadeem, Karan Raja, Mark Attalla, Mitesh Patel, Mona Philips. Safety of Nebulized Colistin Solution as Adjunctive Treatment of Lower Respiratory Tract Infections.
Journal of pharmacy practice.
2022 Feb; 35(1):75-79. doi:
10.1177/0897190020958246. [PMID: 32935618] - Bijayini Behera, Swagata Tripathy, Mahalingam Venkateshan, Ashoka Mahapatra, Srujana Mohanty, Kavita Gupta, Baijayantimala Mishra, P Bhaskar Rao, Jayanta Kumar Mitra, Prasanta Raghab Mohapatra, Manoj Kumar Panigrahi, Sourin Bhuniya, Shakti Kumar Bal. Spectrum of Bacterial Pathogens in Critical COVID-19 Patients Admitted in Intensive Care Units of a Tertiary Care Hospital During the First and Second Wave of the Pandemic.
The Journal of the Association of Physicians of India.
2022 Feb; 70(2):11-12. doi:
NULL. [PMID: 35436819] - Rajkumari Elizabeth, Somorita Baishya, Bubul Kalita, Jayalaxmi Wangkheimayum, Manabendra Dutta Choudhury, Debadatta Dhar Chanda, Amitabha Bhattacharjee. Colistin exposure enhances expression of eptB in colistin-resistant Escherichia coli co-harboring mcr-1.
Scientific reports.
2022 01; 12(1):1348. doi:
10.1038/s41598-022-05435-0. [PMID: 35079093] - Miaomiao Xie, Kaichao Chen, Ning Dong, Qi Xu, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen. Phenotypic Changes Associated With In Vivo Evolution of Colistin Resistance in ST11 Carbapenem-Resistant Klebsiella pneumoniae.
Frontiers in cellular and infection microbiology.
2022; 12(?):841748. doi:
10.3389/fcimb.2022.841748. [PMID: 35281457] - Masego Mmatli, Nontombi Marylucy Mbelle, John Osei Sekyere. Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update.
Frontiers in cellular and infection microbiology.
2022; 12(?):941358. doi:
10.3389/fcimb.2022.941358. [PMID: 36093193] - Malak Khalifeh, Abdalla El-Lakany, Lama Soubra. Acute Kidney Injury Related to Intravenous Colistin Use in Lebanese Hospitalized Patients: Incidence and Associated Factors.
Current drug safety.
2022; 17(2):152-157. doi:
10.2174/1574886316666210728113905. [PMID: 34323193] - Yu Pan, Zhenling Zeng, Huijun Niu, Lang Huang, Jianxin Hu, Guihua Li, Yafei Li. Whole-genome epidemiology and characterisation of mcr-1-encoding Escherichia coli in aquatic bird farms from the Pearl River Delta, China, 2019-2020.
International journal of antimicrobial agents.
2022 Jan; 59(1):106478. doi:
10.1016/j.ijantimicag.2021.106478. [PMID: 34801677] - Zhizeng Sun, Timothy Palzkill. Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1.
mBio.
2021 12; 12(6):e0277621. doi:
10.1128/mbio.02776-21. [PMID: 34781730] - Vijay Tiwari, Pradip R Panta, Caitlin E Billiot, Martin V Douglass, Carmen M Herrera, M Stephen Trent, William T Doerrler. A Klebsiella pneumoniae DedA family membrane protein is required for colistin resistance and for virulence in wax moth larvae.
Scientific reports.
2021 12; 11(1):24365. doi:
10.1038/s41598-021-03834-3. [PMID: 34934166] - Kiran Iqbal Masood, Seema Umar, Zahra Hasan, Joveria Farooqi, Safina Abdul Razzak, Nazish Jabeen, Jason Rao, Sadia Shakoor, Rumina Hasan. Lipid A-Ara4N as an alternate pathway for (colistin) resistance in Klebsiella pneumonia isolates in Pakistan.
BMC research notes.
2021 Dec; 14(1):449. doi:
10.1186/s13104-021-05867-3. [PMID: 34906210] - Aline Vidal Lacerda Gontijo, Sharlene Lopes Pereira, Herval de Lacerda Bonfante. Can Drug Repurposing be Effective Against Carbapenem-Resistant Acinetobacter baumannii?.
Current microbiology.
2021 Dec; 79(1):13. doi:
10.1007/s00284-021-02693-5. [PMID: 34905109] - Wendong Ma, Xukai Jiang, Yujiang Dou, Zhihong Zhang, Jian Li, Bing Yuan, Kai Yang. Biophysical Impact of Lipid A Modification Caused by Mobile Colistin Resistance Gene on Bacterial Outer Membranes.
The journal of physical chemistry letters.
2021 Dec; 12(48):11629-11635. doi:
10.1021/acs.jpclett.1c03295. [PMID: 34817187] - Shuangfang Hu, Ziquan Lv, Yang Wang, Jianzhong Shen, Yuebin Ke. Novel Quadruplex PCR for detecting and genotyping mobile colistin resistance genes in human samples.
Diagnostic microbiology and infectious disease.
2021 Dec; 101(4):115419. doi:
10.1016/j.diagmicrobio.2021.115419. [PMID: 34610496] - Lei Lei, Yongqiang Wang, Junjia He, Chang Cai, Qingzhi Liu, Dawei Yang, Zhiyu Zou, Lingyu Shi, Jianqin Jia, Yang Wang, Timothy R Walsh, Jianzhong Shen, Yougang Zhong. Prevalence and risk analysis of mobile colistin resistance and extended-spectrum β-lactamase genes carriage in pet dogs and their owners: a population based cross-sectional study.
Emerging microbes & infections.
2021 Dec; 10(1):242-251. doi:
10.1080/22221751.2021.1882884. [PMID: 33502946] - Zineb Cherak, Lotfi Loucif, Abdelhamid Moussi, Jean-Marc Rolain. Epidemiology of mobile colistin resistance (mcr) genes in aquatic environments.
Journal of global antimicrobial resistance.
2021 12; 27(?):51-62. doi:
10.1016/j.jgar.2021.07.021. [PMID: 34438108] - Yongchang Xu, Lizhang Liu, Huimin Zhang, Youjun Feng. Co-production of Tet(X) and MCR-1, two resistance enzymes by a single plasmid.
Environmental microbiology.
2021 12; 23(12):7445-7464. doi:
10.1111/1462-2920.15425. [PMID: 33559156] - Diógenes Rodrigues, Giulia Soska Baldissera, Douglas Mathos, Aline Sartori, Alexandre P Zavascki, Maria Helena Rigatto. Amikacin for the treatment of carbapenem-resistant Klebsiella pneumoniae infections: clinical efficacy and toxicity.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology].
2021 Dec; 52(4):1913-1919. doi:
10.1007/s42770-021-00551-x. [PMID: 34191252] - Yun-Jeong Jeong, Namyi Gu, Won Gun Kwack, Yunseong Kang, Seong Yeon Park, Young-Soon Yoon. Prospective observational study of the impact of plasma colistin levels in patients with carbapenem-resistant Acinetobacter baumannii pneumonia.
Journal of global antimicrobial resistance.
2021 12; 27(?):315-323. doi:
10.1016/j.jgar.2021.10.017. [PMID: 34775134] - Aline Vidal Lacerda Gontijo, André V G Cavalieri. Optimal control for colistin dosage selection.
Journal of pharmacokinetics and pharmacodynamics.
2021 12; 48(6):803-813. doi:
10.1007/s10928-021-09769-6. [PMID: 34156631]