Guanosine diphos-phate (BioDeep_00000179626)
human metabolite blood metabolite
代谢物信息卡片
[({[5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid
化学式: C10H15N5O11P2 (443.02433)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
InChI: InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)
描述信息
同义名列表
4 个代谢物同义名
[({[5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid; [({[3,4-dihydroxy-5-(6-hydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonate; {[5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxyphosphonic acid; guanosine diphos-phate
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Plant biotechnology journal.
2008 Apr; 6(3):281-94. doi:
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The EMBO journal.
2008 Mar; 27(5):727-35. doi:
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Molecular plant pathology.
2008 Jan; 9(1):25-36. doi:
10.1111/j.1364-3703.2007.00440.x. [PMID: 18705881] - Timothy E Gookin, Junhyong Kim, Sarah M Assmann. Whole proteome identification of plant candidate G-protein coupled receptors in Arabidopsis, rice, and poplar: computational prediction and in-vivo protein coupling.
Genome biology.
2008; 9(7):R120. doi:
10.1186/gb-2008-9-7-r120. [PMID: 18671868] - Yuhua Zhang, Yifei Wang, Kostya Kanyuka, Martin A J Parry, Stephen J Powers, Nigel G Halford. GCN2-dependent phosphorylation of eukaryotic translation initiation factor-2alpha in Arabidopsis.
Journal of experimental botany.
2008; 59(11):3131-41. doi:
10.1093/jxb/ern169. [PMID: 18603615] - Matthias P Machner, Ralph R Isberg. A bifunctional bacterial protein links GDI displacement to Rab1 activation.
Science (New York, N.Y.).
2007 Nov; 318(5852):974-7. doi:
10.1126/science.1149121. [PMID: 17947549] - John Dowdle, Takahiro Ishikawa, Stephan Gatzek, Susanne Rolinski, Nicholas Smirnoff. Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling viability.
The Plant journal : for cell and molecular biology.
2007 Nov; 52(4):673-89. doi:
10.1111/j.1365-313x.2007.03266.x. [PMID: 17877701] - Marie-Eve Poupart, Delphine Fessart, Mathieu Cotton, Stéphane A Laporte, Audrey Claing. ARF6 regulates angiotensin II type 1 receptor endocytosis by controlling the recruitment of AP-2 and clathrin.
Cellular signalling.
2007 Nov; 19(11):2370-8. doi:
10.1016/j.cellsig.2007.07.015. [PMID: 17719203] - Valentina Buttani, Wolfgang Gärtner, Aba Losi. NTP-binding properties of the blue-light receptor YtvA and effects of the E105L mutation.
European biophysics journal : EBJ.
2007 Sep; 36(7):831-9. doi:
10.1007/s00249-007-0155-1. [PMID: 17443319] - Hsou-Min Li, Muppuru M Kesavulu, Pai-Hsiang Su, Yi-Hung Yeh, Chwan-Deng Hsiao. Toc GTPases.
Journal of biomedical science.
2007 Jul; 14(4):505-8. doi:
10.1007/s11373-007-9166-2. [PMID: 17394099] - Skarlatos G Dedos, Dieter Wicher, Sabine Kaltofen, Heiner Birkenbeil. Different Ca2+ signalling cascades manifested by mastoparan in the prothoracic glands of the tobacco hornworm, Manduca sexta, and the silkworm, Bombyx mori.
Archives of insect biochemistry and physiology.
2007 Jun; 65(2):52-64. doi:
10.1002/arch.20180. [PMID: 17523173] - Pingsheng Liu, René Bartz, John K Zehmer, Yun-shu Ying, Meifang Zhu, Ginette Serrero, Richard G W Anderson. Rab-regulated interaction of early endosomes with lipid droplets.
Biochimica et biophysica acta.
2007 Jun; 1773(6):784-93. doi:
10.1016/j.bbamcr.2007.02.004. [PMID: 17395284] - Jogender Singh Tushir, Crislyn D'Souza-Schorey. ARF6-dependent activation of ERK and Rac1 modulates epithelial tubule development.
The EMBO journal.
2007 Apr; 26(7):1806-19. doi:
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PLoS pathogens.
2007 Mar; 3(3):e48. doi:
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Journal of neuroinflammation.
2006 Nov; 3(?):30. doi:
10.1186/1742-2094-3-30. [PMID: 17094809] - Carla V Finkielstein, Michael Overduin, Daniel G S Capelluto. Cell migration and signaling specificity is determined by the phosphatidylserine recognition motif of Rac1.
The Journal of biological chemistry.
2006 Sep; 281(37):27317-26. doi:
10.1074/jbc.m605560200. [PMID: 16861229] - Lyudmila S Khailova, Elena A Prikhodko, Vera I Dedukhova, Elena N Mokhova, Vasily N Popov, Vladimir P Skulachev. Participation of ATP/ADP antiporter in oleate- and oleate hydroperoxide-induced uncoupling suppressed by GDP and carboxyatractylate.
Biochimica et biophysica acta.
2006 Sep; 1757(9-10):1324-9. doi:
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Cell.
2006 Jul; 126(1):191-203. doi:
10.1016/j.cell.2006.04.045. [PMID: 16839886] - Natalia Leiva, Martín Pavarotti, María I Colombo, María T Damiani. Reconstitution of recycling from the phagosomal compartment in streptolysin O-permeabilized macrophages: role of Rab11.
Experimental cell research.
2006 Jun; 312(10):1843-55. doi:
10.1016/j.yexcr.2006.02.015. [PMID: 16563376] - Ahmed Chahdi, Andrey Sorokin. Endothelin 1 stimulates beta1Pix-dependent activation of Cdc42 through the G(salpha) pathway.
Experimental biology and medicine (Maywood, N.J.).
2006 Jun; 231(6):761-5. doi:
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Journal of structural biology.
2006 Jun; 154(3):260-8. doi:
10.1016/j.jsb.2006.01.007. [PMID: 16545962] - Stéphanie Klein, Michel Franco, Pierre Chardin, Frédéric Luton. Role of the Arf6 GDP/GTP cycle and Arf6 GTPase-activating proteins in actin remodeling and intracellular transport.
The Journal of biological chemistry.
2006 May; 281(18):12352-61. doi:
10.1074/jbc.m601021200. [PMID: 16527809] - Maria Zeniou Meyer, Nadine Déliot, Sylvette Chasserot-Golaz, Richard T Premont, Marie-France Bader, Nicolas Vitale. Regulation of neuroendocrine exocytosis by the ARF6 GTPase-activating protein GIT1.
The Journal of biological chemistry.
2006 Mar; 281(12):7919-26. doi:
10.1074/jbc.m600081200. [PMID: 16439353] - Keiichi Kameyama, Allen P Minton. Rapid quantitative characterization of protein interactions by composition gradient static light scattering.
Biophysical journal.
2006 Mar; 90(6):2164-9. doi:
10.1529/biophysj.105.074310. [PMID: 16387762] - Leszek Domanski, Tadeusz Sulikowski, Krzysztof Safranow, Andrzej Pawlik, Maria Olszewska, Dariusz Chlubek, Elzbieta Urasinska, Kazimierz Ciechanowski. Effect of trimetazidine on the nucleotide profile in rat kidney with ischemia-reperfusion injury.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2006 Mar; 27(4):320-7. doi:
10.1016/j.ejps.2005.10.012. [PMID: 16387483] - Wei Tang, Yaping Tu, Surendra K Nayak, Jimmy Woodson, Markus Jehl, Elliott M Ross. Gbetagamma inhibits Galpha GTPase-activating proteins by inhibition of Galpha-GTP binding during stimulation by receptor.
The Journal of biological chemistry.
2006 Feb; 281(8):4746-53. doi:
10.1074/jbc.m510573200. [PMID: 16407201] - Sunil K Saxena, Madhurima Singh, Hiroshi Shibata, Simarna Kaur, Constantine George. Rab4 GTP/GDP modulates amiloride-sensitive sodium channel (ENaC) function in colonic epithelia.
Biochemical and biophysical research communications.
2006 Feb; 340(2):726-33. doi:
10.1016/j.bbrc.2005.12.036. [PMID: 16389071] - Bruno Mesmin, Bruno Antonny. GEF and glucosylation assays on liposome-bound Rac.
Methods in enzymology.
2006; 406(?):70-80. doi:
10.1016/s0076-6879(06)06006-x. [PMID: 16472650] - Adam Shutes, Anastacia C Berzat, Emily J Chenette, Adrienne D Cox, Channing J Der. Biochemical analyses of the Wrch atypical Rho family GTPases.
Methods in enzymology.
2006; 406(?):11-26. doi:
10.1016/s0076-6879(06)06002-2. [PMID: 16472646] - Kazutoshi Takahashi, Masato Nakagawa, Stephen G Young, Shinya Yamanaka. Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway.
The Journal of biological chemistry.
2005 Sep; 280(38):32768-74. doi:
10.1074/jbc.m506280200. [PMID: 16046393] - Darren A Talbot, Martin D Brand. Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria.
Biochimica et biophysica acta.
2005 Sep; 1709(2):150-6. doi:
10.1016/j.bbabio.2005.07.001. [PMID: 16084485] - Ozlem Ugur, Sükrü Sadik Oner, Paola Molinari, Caterina Ambrosio, Kemal Sayar, H Ongun Onaran. Guanine nucleotide exchange-independent activation of Gs protein by beta2-adrenoceptor.
Molecular pharmacology.
2005 Sep; 68(3):720-8. doi:
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American journal of physiology. Endocrinology and metabolism.
2005 Sep; 289(3):E456-65. doi:
10.1152/ajpendo.00053.2005. [PMID: 15855228] - Hye-Won Shin, Hiromi Kobayashi, Masashi Kitamura, Satoshi Waguri, Tatsuo Suganuma, Yasuo Uchiyama, Kazuhisa Nakayama. Roles of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane trafficking.
Journal of cell science.
2005 Sep; 118(Pt 17):4039-48. doi:
10.1242/jcs.02524. [PMID: 16129887] - Antje Berken, Christoph Thomas, Alfred Wittinghofer. A new family of RhoGEFs activates the Rop molecular switch in plants.
Nature.
2005 Aug; 436(7054):1176-80. doi:
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