3-Hydroxy-carbofuran (BioDeep_00000017959)

   

human metabolite


代谢物信息卡片


1-[(3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-N-methylmethanimidic acid

化学式: C12H15NO4 (237.100103)
中文名称: 3-羟基呋喃丹
谱图信息: 最多检出来源 Anoectochilus roxburghii(viridiplantae) 66.67%

分子结构信息

SMILES: CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C
InChI: InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)

描述信息

3-Hydroxy-carbofuran is a metabolite of Carbofuran in plants, insects and mammals.
Metabolite of Carbofuran in plants, insects and mammals.

同义名列表

10 个代谢物同义名

1-[(3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-N-methylmethanimidic acid; 1-[(3-Hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-N-methylmethanimidate; 1-[(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl)oxy]-N-methylmethanimidic acid; 2,3-dihydro-2,2-Dimethyl-3,7-benzofurandiol 7-(methylcarbamate); Carbofuran, 3-hydroxy; 3-Hydroxy-carbofuran; 3-Hydroxy Carbofuran; Carbofuran-3-hydroxy; 3-HYDROXYCARBOFURAN; Carbofuran 3-OH



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lihong Shi, Hongbin Lang, Jiatao Shen, Fan Shen, Jialu Song, Luqing Zhang, Hua Fang, Yunlong Yu. Absorption, metabolism and distribution of carbosulfan in maize plants (Zea mays L.). Pest management science. 2023 May; ?(?):. doi: 10.1002/ps.7586. [PMID: 37245216]
  • Thirumalaiandi Ramasubramanian, Mariappan Paramasivam. Persistence and metabolism of carbofuran in the soil and sugarcane plant. Environmental monitoring and assessment. 2018 Aug; 190(9):538. doi: 10.1007/s10661-018-6926-6. [PMID: 30132217]
  • Chang P Zhang, Hong M He, Jian Z Yu, Xiu Q Hu, Ya H Zhu, Qiang Wang. Residues of carbosulfan and its metabolites carbofuran and 3-hydroxy carbofuran in rice field ecosystem in China. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2016; 51(6):351-7. doi: 10.1080/03601234.2015.1120606. [PMID: 26963425]
  • Peter O Otieno, Joseph O Lalah, Munir Virani, Isaac O Jondiko, Karl-Werner Schramm. Soil and water contamination with carbofuran residues in agricultural farmlands in Kenya following the application of the technical formulation Furadan. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2010 Feb; 45(2):137-44. doi: 10.1080/03601230903472058. [PMID: 20390943]
  • Xiaofei Zhang, Andy M Tsang, Miles S Okino, Frederick W Power, James B Knaak, Lynda S Harrison, Curtis C Dary. A physiologically based pharmacokinetic/pharmacodynamic model for carbofuran in Sprague-Dawley rats using the exposure-related dose estimating model. Toxicological sciences : an official journal of the Society of Toxicology. 2007 Dec; 100(2):345-59. doi: 10.1093/toxsci/kfm232. [PMID: 17804862]
  • Syrago-Styliani E Petropoulou, Evagelos Gikas, Anthony Tsarbopoulos, Panayotis A Siskos. Gas chromatographic-tandem mass spectrometric method for the quantitation of carbofuran, carbaryl and their main metabolites in applicators' urine. Journal of chromatography. A. 2006 Mar; 1108(1):99-110. doi: 10.1016/j.chroma.2005.12.058. [PMID: 16442549]
  • Kwang-Hyeon Liu, Ha-Jung Sung, Hae-Keun Lee, Byung-Hun Song, Yang-Bin Ihm, Kyun Kim, Hye-Suk Lee, Jeong-Han Kim. Dermal pharmacokinetics of the insecticide furathiocarb in rats. Pest management science. 2002 Jan; 58(1):57-62. doi: 10.1002/ps.422. [PMID: 11838286]
  • A K Salama. Metabolism of carbofuran by Aspergillus niger and Fusarium graminearum. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1998 May; 33(3):253-66. doi: 10.1080/03601239809373142. [PMID: 9604338]
  • J Huang, S Zhang, M Ding, A Zhou, J Zhang, J Zhang. Acute effects of carbofuran in workers of two pesticide plants. La Medicina del lavoro. 1998; 89 Suppl 2(?):S105-11. doi: . [PMID: 10217931]
  • P W Ferguson, M S Dey, S A Jewell, R I Krieger. Carbofuran metabolism and toxicity in the rat. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1984 Feb; 4(1):14-21. doi: 10.1016/0272-0590(84)90215-x. [PMID: 6693000]