Glycidamide (BioDeep_00000179535)
human metabolite blood metabolite
代谢物信息卡片
oxirane-2-carboximidic acid
化学式: C3H5NO2 (87.032027)
中文名称: 环氧丙酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(O1)C(=O)N
InChI: InChI=1S/C3H5NO2/c4-3(5)2-1-6-2/h2H,1H2,(H2,4,5)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Banu Orta Yilmaz, Yasemin Aydin. Dynamic assessment of the relationship between oxidative stress and apoptotic pathway in embryonic fibroblast cells exposed to glycidamide: possible protective role of hesperidin.
Environmental science and pollution research international.
2023 Feb; ?(?):. doi:
10.1007/s11356-023-26108-z. [PMID: 36853541] - Yung-Wen Cheng, Chun-Chi Hung, Tung-Wei Kao, Wei-Liang Chen. Health risks of dual use of electronic and combustible cigarettes: exposure to acrylamide and glycidamide.
Polish archives of internal medicine.
2022 01; 132(1):. doi:
10.20452/pamw.16103. [PMID: 34612028] - Yu-Syuan Luo, Tai-Ying Long, Su-Yin Chiang, Kuen-Yuh Wu. Characterization of primary glutathione conjugates with acrylamide and glycidamide: Toxicokinetic studies in Sprague Dawley rats treated with acrylamide.
Chemico-biological interactions.
2021 Dec; 350(?):109701. doi:
10.1016/j.cbi.2021.109701. [PMID: 34656557] - Iokfai Cheang, Shengen Liao, Xu Zhu, Xinyi Lu, Qingqing Zhu, Wenming Yao, Yanli Zhou, Haifeng Zhang, Xinli Li. Association of acrylamide hemoglobin biomarkers with serum lipid levels in general US population: NHANES 2013-2016.
Ecotoxicology and environmental safety.
2021 May; 214(?):112111. doi:
10.1016/j.ecoenv.2021.112111. [PMID: 33690009] - Banu Orta Yilmaz, Nebahat Yildizbayrak, Yasemin Aydin. Vitamin C inhibits glycidamide-induced genotoxicity and apoptosis in Sertoli cells.
Journal of biochemical and molecular toxicology.
2020 Sep; 34(9):e22545. doi:
10.1002/jbt.22545. [PMID: 32632975] - Xinyu Chen, Wei Jia, Qiao Wang, Jianxin Han, Jun Cheng, Weijiang Zeng, Qingning Zhao, Yu Zhang, Ying Zhang. Protective effect of a dietary flavonoid-rich antioxidant from bamboo leaves against internal exposure to acrylamide and glycidamide in humans.
Food & function.
2020 Aug; 11(8):7000-7011. doi:
10.1039/d0fo00811g. [PMID: 32812964] - Yiju Zhang, Qiao Wang, Wei Jia, Jun Cheng, Li Zhu, Yiping Ren, Yu Zhang. Rapid Simultaneous Determination of Cascade Metabolites of Acrylamide in Urine for Toxicokinetics Profiles and Short-Term Dietary Internal Exposure.
Journal of agricultural and food chemistry.
2020 Jun; 68(24):6748-6758. doi:
10.1021/acs.jafc.0c01685. [PMID: 32419456] - Pei-Lun Chu, Hui-Shan Liu, Chikang Wang, Chien-Yu Lin. Association between acrylamide exposure and sex hormones in males: NHANES, 2003-2004.
PloS one.
2020; 15(6):e0234622. doi:
10.1371/journal.pone.0234622. [PMID: 32555690] - Maria Zhivagui, Alvin W T Ng, Maude Ardin, Mona I Churchwell, Manuraj Pandey, Claire Renard, Stephanie Villar, Vincent Cahais, Alexis Robitaille, Liacine Bouaoun, Adriana Heguy, Kathryn Z Guyton, Martha R Stampfer, James McKay, Monica Hollstein, Magali Olivier, Steven G Rozen, Frederick A Beland, Michael Korenjak, Jiri Zavadil. Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans.
Genome research.
2019 04; 29(4):521-531. doi:
10.1101/gr.242453.118. [PMID: 30846532] - Pengpu Wang, Rongrong Ji, Junfu Ji, Fang Chen. Changes of metabolites of acrylamide and glycidamide in acrylamide-exposed rats pretreated with blueberry anthocyanins extract.
Food chemistry.
2019 Feb; 274(?):611-619. doi:
10.1016/j.foodchem.2018.08.058. [PMID: 30372986] - Kelsey A Behrens, Leigh A Jania, John N Snouwaert, MyTrang Nguyen, Sheryl S Moy, Andrey P Tikunov, Jeffrey M Macdonald, Beverly H Koller. Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile.
PloS one.
2019; 14(11):e0225449. doi:
10.1371/journal.pone.0225449. [PMID: 31747445] - B O Yilmaz, N Yildizbayrak, Y Aydin, M Erkan. Evidence of acrylamide- and glycidamide-induced oxidative stress and apoptosis in Leydig and Sertoli cells.
Human & experimental toxicology.
2017 Dec; 36(12):1225-1235. doi:
10.1177/0960327116686818. [PMID: 28067054] - Mireia Obón-Santacana, Leila Lujan-Barroso, Heinz Freisling, Claire Cadeau, Guy Fagherazzi, Marie-Christine Boutron-Ruault, Rudolf Kaaks, Renée T Fortner, Heiner Boeing, J Ramón Quirós, Esther Molina-Montes, Saioa Chamosa, José María Huerta Castaño, Eva Ardanaz, Kay-Tee Khaw, Nick Wareham, Tim Key, Antonia Trichopoulou, Pagona Lagiou, Androniki Naska, Domenico Palli, Sara Grioni, Rosario Tumino, Paolo Vineis, Maria Santucci De Magistris, H B Bueno-de-Mesquita, Petra H Peeters, Maria Wennberg, Ingvar A Bergdahl, Hubert Vesper, Elio Riboli, Eric J Duell. Dietary and lifestyle determinants of acrylamide and glycidamide hemoglobin adducts in non-smoking postmenopausal women from the EPIC cohort.
European journal of nutrition.
2017 Apr; 56(3):1157-1168. doi:
10.1007/s00394-016-1165-5. [PMID: 26850269] - Alice Thürer, Michael Granvogl. Generation of Desired Aroma-Active as Well as Undesired Toxicologically Relevant Compounds during Deep-Frying of Potatoes with Different Edible Vegetable Fats and Oils.
Journal of agricultural and food chemistry.
2016 Nov; 64(47):9107-9115. doi:
10.1021/acs.jafc.6b04749. [PMID: 27806575] - Daotong Li, Pengpu Wang, Yanbing Liu, Xiaosong Hu, Fang Chen. Metabolism of Acrylamide: Interindividual and Interspecies Differences as Well as the Application as Biomarkers.
Current drug metabolism.
2016; 17(4):317-26. doi:
10.2174/1389200216666151015115007. [PMID: 26467066] - Natalia Kotova, Cecilia Frostne, Lilianne Abramsson-Zetterberg, Eden Tareke, Rolf Bergman, Siamak Haghdoost, Birgit Paulsson, Margareta Törnqvist, Dan Segerbäck, Dag Jenssen, Jan Grawé. Differences in micronucleus frequency and acrylamide adduct levels with hemoglobin between vegetarians and non-vegetarians.
European journal of nutrition.
2015 Oct; 54(7):1181-90. doi:
10.1007/s00394-014-0796-7. [PMID: 25399061] - C Sams, K Jones, N Warren, J Cocker, S Bell, P Bull, M Cain. Towards a biological monitoring guidance value for acrylamide.
Toxicology letters.
2015 Aug; 237(1):30-7. doi:
10.1016/j.toxlet.2015.05.018. [PMID: 26024765] - Yu-Syuan Luo, Tai-Ying Long, Li-Ching Shen, Shou-Ling Huang, Su-Yin Chiang, Kuen-Yuh Wu. Synthesis, characterization and analysis of the acrylamide- and glycidamide-glutathione conjugates.
Chemico-biological interactions.
2015 Jul; 237(?):38-46. doi:
10.1016/j.cbi.2015.05.002. [PMID: 25980586] - En-Ting Wang, Dong-Yan Chen, Huang-You Liu, Hai-Yang Yan, Yuan Yuan. Protective effect of allicin against glycidamide-induced toxicity in male and female mice.
General physiology and biophysics.
2015 Apr; 34(2):177-87. doi:
10.4149/gpb_2014038. [PMID: 25730897] - Tae Hwan Kim, Soyoung Shin, Kyu Bong Kim, Won Sik Seo, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo, Seok Won Jeong, Beom Soo Shin. Determination of acrylamide and glycidamide in various biological matrices by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study.
Talanta.
2015 Jan; 131(?):46-54. doi:
10.1016/j.talanta.2014.07.042. [PMID: 25281071] - Nico Watzek, Denise Scherbl, Markus Schug, Jan G Hengstler, Matthias Baum, Michael Habermeyer, Elke Richling, Gerhard Eisenbrand. Toxicokinetics of acrylamide in primary rat hepatocytes: coupling to glutathione is faster than conversion to glycidamide.
Archives of toxicology.
2013 Aug; 87(8):1545-56. doi:
10.1007/s00204-013-1054-0. [PMID: 23568512] - L Camacho, J R Latendresse, L Muskhelishvili, R Patton, J F Bowyer, M Thomas, D R Doerge. Effects of acrylamide exposure on serum hormones, gene expression, cell proliferation, and histopathology in male reproductive tissues of Fischer 344 rats.
Toxicology letters.
2012 Jun; 211(2):135-43. doi:
10.1016/j.toxlet.2012.03.007. [PMID: 22459607] - S M Hamdy, H M Bakeer, E F Eskander, O N Sayed. Effect of acrylamide on some hormones and endocrine tissues in male rats.
Human & experimental toxicology.
2012 May; 31(5):483-91. doi:
10.1177/0960327111417267. [PMID: 21878450] - Minxue Shen, Zhenqiu Sun, Jingcheng Shi, Ming Hu, Jingxuan Hu, Yanhong Liu. [Prohibited substances in cosmetics: prospect of the toxicity of acrylamide].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
2012 Apr; 37(4):424-30. doi:
10.3969/j.issn.1672-7347.2012.04.019. [PMID: 22561576] - Julia M Latzin, Birgit K Schindler, Tobias Weiss, Jürgen Angerer, Holger M Koch. Determination of 2,3-dihydroxypropionamide, an oxidative metabolite of acrylamide, in human urine by gas chromatography coupled with mass spectrometry.
Analytical and bioanalytical chemistry.
2012 Mar; 402(7):2431-8. doi:
10.1007/s00216-011-5692-x. [PMID: 22278074] - Nico Watzek, Nadine Böhm, Julia Feld, Denise Scherbl, Franz Berger, Karl Heinz Merz, Alfonso Lampen, Thorsten Reemtsma, Steven R Tannenbaum, Paul L Skipper, Matthias Baum, Elke Richling, Gerhard Eisenbrand. N7-glycidamide-guanine DNA adduct formation by orally ingested acrylamide in rats: a dose-response study encompassing human diet-related exposure levels.
Chemical research in toxicology.
2012 Feb; 25(2):381-90. doi:
10.1021/tx200446z. [PMID: 22211389] - Taewon Lee, Mugimane G Manjanatha, Anane Aidoo, Carrie L Moland, William S Branham, James C Fuscoe, Akhtar A Ali, Varsha G Desai. Expression analysis of hepatic mitochondria-related genes in mice exposed to acrylamide and glycidamide.
Journal of toxicology and environmental health. Part A.
2012; 75(6):324-39. doi:
10.1080/15287394.2012.668160. [PMID: 22480170] - William J Moorman, Susan S Reutman, Peter B Shaw, Leo Michael Blade, David Marlow, Hubert Vesper, John C Clark, Steven M Schrader. Occupational exposure to acrylamide in closed system production plants: air levels and biomonitoring.
Journal of toxicology and environmental health. Part A.
2012; 75(2):100-11. doi:
10.1080/15287394.2011.615109. [PMID: 22129237] - Joanna Michalak, Elżbieta Gujska, Joanna Klepacka. The effect of domestic preparation of some potato products on acrylamide content.
Plant foods for human nutrition (Dordrecht, Netherlands).
2011 Nov; 66(4):307-12. doi:
10.1007/s11130-011-0252-2. [PMID: 21853292] - Yu-Fang Huang, Mei-Lien Chen, Saou-Hsing Liou, Ming-Feng Chen, Shi-Nian Uang, Kuen-Yuh Wu. Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide.
Toxicology letters.
2011 Jun; 203(2):118-26. doi:
10.1016/j.toxlet.2011.03.008. [PMID: 21402133] - Eva C Hartmann, Julia M Latzin, Birgit K Schindler, Holger M Koch, Jürgen Angerer. Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamide.
Archives of toxicology.
2011 Jun; 85(6):601-6. doi:
10.1007/s00204-010-0605-x. [PMID: 20953585] - Franz Ingo Berger, Julia Feld, Daniel Bertow, Gerhard Eisenbrand, Gert Fricker, Natalie Gerhardt, Karl-Heinz Merz, Elke Richling, Matthias Baum. Biological effects of acrylamide after daily ingestion of various foods in comparison to water: a study in rats.
Molecular nutrition & food research.
2011 Mar; 55(3):387-99. doi:
10.1002/mnfr.201000234. [PMID: 20938989] - Chia-Hsien Feng, Chi-Yu Lu. Modification of major plasma proteins by acrylamide and glycidamide: Preliminary screening by nano liquid chromatography with tandem mass spectrometry.
Analytica chimica acta.
2011 Jan; 684(1-2):80-6. doi:
10.1016/j.aca.2010.10.042. [PMID: 21167989] - Kaci N Pruser, Nick E Flynn. Acrylamide in health and disease.
Frontiers in bioscience (Scholar edition).
2011 01; 3(1):41-51. doi:
10.2741/s130. [PMID: 21196355] - Sherry A Ferguson, Joan Garey, Melody E Smith, Nathan C Twaddle, Daniel R Doerge, Merle G Paule. Preweaning behaviors, developmental landmarks, and acrylamide and glycidamide levels after pre- and postnatal acrylamide treatment in rats.
Neurotoxicology and teratology.
2010 May; 32(3):373-82. doi:
10.1016/j.ntt.2010.01.010. [PMID: 20117204] - Hubert W Vesper, Samuel P Caudill, John D Osterloh, Tunde Meyers, Deanna Scott, Gary L Myers. Exposure of the U.S. population to acrylamide in the National Health and Nutrition Examination Survey 2003-2004.
Environmental health perspectives.
2010 Feb; 118(2):278-83. doi:
10.1289/ehp.0901021. [PMID: 20123601] - Lisa M Sweeney, Christopher R Kirman, Michael L Gargas, M Leigh Carson, Robert G Tardiff. Development of a physiologically-based toxicokinetic model of acrylamide and glycidamide in rats and humans.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2010 Feb; 48(2):668-85. doi:
10.1016/j.fct.2009.11.049. [PMID: 19948202] - Chien-Yu Lin, Yu-Chuan Lin, Hsu-Ko Kuo, Juey-Jen Hwang, Jiunn-Lee Lin, Pau-Chung Chen, Lian-Yu Lin. Association among acrylamide, blood insulin, and insulin resistance in adults.
Diabetes care.
2009 Dec; 32(12):2206-11. doi:
10.2337/dc09-0309. [PMID: 19729525] - Eva C Hartmann, Melanie I Boettcher, Hermann M Bolt, Hans Drexler, Jürgen Angerer. N-Acetyl-S-(1-carbamoyl-2-hydroxy-ethyl)-L-cysteine (iso-GAMA) a further product of human metabolism of acrylamide: comparison with the simultaneously excreted other mercaptuic acids.
Archives of toxicology.
2009 Jul; 83(7):731-4. doi:
10.1007/s00204-008-0369-8. [PMID: 18949457] - Ursel Heudorf, Eva Hartmann, Jürgen Angerer. Acrylamide in children--exposure assessment via urinary acrylamide metabolites as biomarkers.
International journal of hygiene and environmental health.
2009 Mar; 212(2):135-41. doi:
10.1016/j.ijheh.2008.04.006. [PMID: 18555743] - Eva Katharina Kopp, Wolfgang Dekant. Toxicokinetics of acrylamide in rats and humans following single oral administration of low doses.
Toxicology and applied pharmacology.
2009 Mar; 235(2):135-42. doi:
10.1016/j.taap.2008.12.001. [PMID: 19118568] - Xichun Zhang, Fahe Chen, Zhiyong Huang. Apoptosis induced by acrylamide is suppressed in a 21.5\% fat diet through caspase-3-independent pathway in mice testis.
Toxicology mechanisms and methods.
2009 Mar; 19(3):219-24. doi:
10.1080/15376510802499048. [PMID: 19750022] - Eva K Kopp, Maximilian Sieber, Marco Kellert, Wolfgang Dekant. Rapid and sensitive HILIC-ESI-MS/MS quantitation of polar metabolites of acrylamide in human urine using column switching with an online trap column.
Journal of agricultural and food chemistry.
2008 Nov; 56(21):9828-34. doi:
10.1021/jf801715f. [PMID: 18841985] - Caius M Rommens, Hua Yan, Kathy Swords, Craig Richael, Jingsong Ye. Low-acrylamide French fries and potato chips.
Plant biotechnology journal.
2008 Oct; 6(8):843-53. doi:
10.1111/j.1467-7652.2008.00363.x. [PMID: 18662372] - Eva C Hartmann, Melanie I Boettcher, Thomas Schettgen, Hermann Fromme, Hans Drexler, Jürgen Angerer. Hemoglobin adducts and mercapturic acid excretion of acrylamide and glycidamide in one study population.
Journal of agricultural and food chemistry.
2008 Aug; 56(15):6061-8. doi:
10.1021/jf800277h. [PMID: 18624428] - Michael Granvogl, Peter Koehler, Larissa Latzer, Peter Schieberle. Development of a stable isotope dilution assay for the quantitation of glycidamide and its application to foods and model systems.
Journal of agricultural and food chemistry.
2008 Aug; 56(15):6087-92. doi:
10.1021/jf800280b. [PMID: 18624425] - Sean M Hays, Lesa L Aylward. Biomonitoring Equivalents (BE) dossier for acrylamide (AA) (CAS No. 79-06-1).
Regulatory toxicology and pharmacology : RTP.
2008 Aug; 51(3 Suppl):S57-67. doi:
10.1016/j.yrtph.2008.05.010. [PMID: 18583007] - J F Bowyer, J R Latendresse, R R Delongchamp, L Muskhelishvili, A R Warbritton, M Thomas, E Tareke, L P McDaniel, D R Doerge. The effects of subchronic acrylamide exposure on gene expression, neurochemistry, hormones, and histopathology in the hypothalamus-pituitary-thyroid axis of male Fischer 344 rats.
Toxicology and applied pharmacology.
2008 Jul; 230(2):208-15. doi:
10.1016/j.taap.2008.02.028. [PMID: 18430446] - Thomas Bjellaas, Hege B A Ølstørn, Georg Becher, Jan Alexander, Svein H Knutsen, Jan E Paulsen. Urinary metabolites as biomarkers of acrylamide exposure in mice following dietary crisp bread administration or subcutaneous injection.
Toxicological sciences : an official journal of the Society of Toxicology.
2007 Dec; 100(2):374-80. doi:
10.1093/toxsci/kfm234. [PMID: 17823452] - Hubert W Vesper, John T Bernert, Maria Ospina, Tunde Meyers, Leigha Ingham, Antoinette Smith, Gary L Myers. Assessment of the relation between biomarkers for smoking and biomarkers for acrylamide exposure in humans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2007 Nov; 16(11):2471-8. doi:
10.1158/1055-9965.epi-06-1058. [PMID: 18006939] - Thomas Bjellaas, Linn Helene Stølen, Margaretha Haugen, Jan Erik Paulsen, Jan Alexander, Elsa Lundanes, Georg Becher. Urinary acrylamide metabolites as biomarkers for short-term dietary exposure to acrylamide.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2007 Jun; 45(6):1020-6. doi:
10.1016/j.fct.2006.12.007. [PMID: 17258374] - Daniel R Doerge, Nathan C Twaddle, Melanie I Boettcher, L Patrice McDaniel, Jürgen Angerer. Urinary excretion of acrylamide and metabolites in Fischer 344 rats and B6C3F(1) mice administered a single dose of acrylamide.
Toxicology letters.
2007 Feb; 169(1):34-42. doi:
10.1016/j.toxlet.2006.12.002. [PMID: 17224249] - Melanie I Boettcher, Hermann M Bolt, Jürgen Angerer. Acrylamide exposure via the diet: influence of fasting on urinary mercapturic acid metabolite excretion in humans.
Archives of toxicology.
2006 Dec; 80(12):817-9. doi:
10.1007/s00204-006-0123-z. [PMID: 16783545] - Marco Kellert, Karoline Scholz, Silvia Wagner, Wolfgang Dekant, Wolfgang Völkel. Quantitation of mercapturic acids from acrylamide and glycidamide in human urine using a column switching tool with two trap columns and electrospray tandem mass spectrometry.
Journal of chromatography. A.
2006 Oct; 1131(1-2):58-66. doi:
10.1016/j.chroma.2006.07.026. [PMID: 16884730] - Michael Urban, Dominique Kavvadias, Kirsten Riedel, Gerhard Scherer, Anthony R Tricker. Urinary mercapturic acids and a hemoglobin adduct for the dosimetry of acrylamide exposure in smokers and nonsmokers.
Inhalation toxicology.
2006 Sep; 18(10):831-9. doi:
10.1080/08958370600748430. [PMID: 16774873] - Melanie I Boettcher, Hermann M Bolt, Hans Drexler, Jürgen Angerer. Excretion of mercapturic acids of acrylamide and glycidamide in human urine after single oral administration of deuterium-labelled acrylamide.
Archives of toxicology.
2006 Feb; 80(2):55-61. doi:
10.1007/s00204-005-0011-y. [PMID: 16180013] - Uwe Fuhr, Melanie I Boettcher, Martina Kinzig-Schippers, Alexandra Weyer, Alexander Jetter, Andreas Lazar, Dirk Taubert, Dorota Tomalik-Scharte, Panagiota Pournara, Verena Jakob, Stefanie Harlfinger, Tobias Klaassen, Albrecht Berkessel, Jürgen Angerer, Fritz Sörgel, Edgar Schömig. Toxicokinetics of acrylamide in humans after ingestion of a defined dose in a test meal to improve risk assessment for acrylamide carcinogenicity.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2006 Feb; 15(2):266-71. doi:
10.1158/1055-9965.epi-05-0647. [PMID: 16492914] - Burhan I Ghanayem, L Patrice McDaniel, Mona I Churchwell, Nathan C Twaddle, Rodney Snyder, Timothy R Fennell, Daniel R Doerge. Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 Dec; 88(2):311-8. doi:
10.1093/toxsci/kfi307. [PMID: 16141435] - Daniel R Doerge, John F Young, L Patrice McDaniel, Nathan C Twaddle, Mona I Churchwell. Toxicokinetics of acrylamide and glycidamide in Fischer 344 rats.
Toxicology and applied pharmacology.
2005 Nov; 208(3):199-209. doi:
10.1016/j.taap.2005.03.003. [PMID: 16239164] - Melanie Isabell Boettcher, Jürgen Angerer. Determination of the major mercapturic acids of acrylamide and glycidamide in human urine by LC-ESI-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Sep; 824(1-2):283-94. doi:
10.1016/j.jchromb.2005.07.042. [PMID: 16111925] - Timothy R Fennell, Susan C J Sumner, Rodney W Snyder, Jason Burgess, Rebecca Spicer, William E Bridson, Marvin A Friedman. Metabolism and hemoglobin adduct formation of acrylamide in humans.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 May; 85(1):447-59. doi:
10.1093/toxsci/kfi069. [PMID: 15625188] - Daniel R Doerge, Gonçalo Gamboa da Costa, L Patrice McDaniel, Mona I Churchwell, Nathan C Twaddle, Frederick A Beland. DNA adducts derived from administration of acrylamide and glycidamide to mice and rats.
Mutation research.
2005 Feb; 580(1-2):131-41. doi:
10.1016/j.mrgentox.2004.10.013. [PMID: 15668115] - Melanie Isabell Boettcher, Thomas Schettgen, Birgitta Kütting, Monika Pischetsrieder, Jürgen Angerer. Mercapturic acids of acrylamide and glycidamide as biomarkers of the internal exposure to acrylamide in the general population.
Mutation research.
2005 Feb; 580(1-2):167-76. doi:
10.1016/j.mrgentox.2004.11.010. [PMID: 15668118] - Jerry M Rice. The carcinogenicity of acrylamide.
Mutation research.
2005 Feb; 580(1-2):3-20. doi:
10.1016/j.mrgentox.2004.09.008. [PMID: 15668103] - Daniel R Doerge, John F Young, L Patrice McDaniel, Nathan C Twaddle, Mona I Churchwell. Toxicokinetics of acrylamide and glycidamide in B6C3F1 mice.
Toxicology and applied pharmacology.
2005 Feb; 202(3):258-67. doi:
10.1016/j.taap.2004.07.001. [PMID: 15667831] - Matthias Baum, Evelyne Fauth, Silke Fritzen, Armin Herrmann, Peter Mertes, Melanie Rudolphi, Thomas Spormann, Heinrich Zankl, Gerhard Eisenbrand, Daniel Bertow. Acrylamide and glycidamide: approach towards risk assessment based on biomarker guided dosimetry of genotoxic/mutagenic effects in human blood.
Advances in experimental medicine and biology.
2005; 561(?):77-88. doi:
10.1007/0-387-24980-x_6. [PMID: 16438290] - Timothy R Fennell, Marvin A Friedman. Comparison of acrylamide metabolism in humans and rodents.
Advances in experimental medicine and biology.
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