Glutathione monoisopropyl ester (BioDeep_00000179498)
human metabolite blood metabolite
代谢物信息卡片
化学式: C13H23N3O6S (349.1307)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: CC(C)OC(=O)CNC(=O)C(CS)NC(=O)CCC(C(=O)O)N
InChI: InChI=1S/C13H23N3O6S/c1-7(2)22-11(18)5-15-12(19)9(6-23)16-10(17)4-3-8(14)13(20)21/h7-9,23H,3-6,14H2,1-2H3,(H,15,19)(H,16,17)(H,20,21)
描述信息
同义名列表
10 个代谢物同义名
2-amino-4-[(1-{[2-oxo-2-(propan-2-yloxy)ethyl]carbamoyl}-2-sulfanylethyl)carbamoyl]butanoic acid; 2-amino-4-({1-[(2-isopropoxy-2-oxoethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)butanoic acid; N-(N-L-Glutamyl-L-cysteinyl)glycine 1-isopropyl ester sulfate monohydrate; Glutathione monoisopropyl ester, monoisopropyl ester; Glutathione monoisopropyl ester, sulfate salt (2:1); Glutathione monoisopropyl ester, sulfate salt; Glutathione monoisopropyl ester; Glutathione isopropyl ester; H-DL-gGlu-DL-Cys-Gly-OiPr; GSH Monoisopropyl ester
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Li-Tung Huang, Mao-Meng Tiao, You-Lin Tain, Chih-Cheng Chen, Chih-Sung Hsieh. Melatonin ameliorates bile duct ligation-induced systemic oxidative stress and spatial memory deficits in developing rats.
Pediatric research.
2009 Feb; 65(2):176-80. doi:
10.1203/pdr.0b013e31818d5bc7. [PMID: 19047958] - Shu Zhang, Fei-Yan Chai, Hong Yan, Yong Guo, J J Harding. Effects of N-acetylcysteine and glutathione ethyl ester drops on streptozotocin-induced diabetic cataract in rats.
Molecular vision.
2008 May; 14(?):862-70. doi:
NULL. [PMID: 18490958] - M Perwaiz Iqbal, Naseema Mehboobali, Shahid Pervez. Plaque formation reduction with glutathione monoester in mice fed on atherogenic diet.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.
2006 Sep; 16(9):571-5. doi:
9.2006/jcpsp.571575. [PMID: 16945228] - S Kobayashi, M Takehana, C Tohyama. Glutathione isopropyl ester reduces UVB-induced skin damage in hairless mice.
Photochemistry and photobiology.
1996 Jan; 63(1):106-10. doi:
10.1111/j.1751-1097.1996.tb02999.x. [PMID: 8577862] - E Babu, V K Gopalakrishnan, I N Sriganth, R Gopalakrishnan, D Sakthisekaran. Cisplatin induced nephrotoxicity and the modulating effect of glutathione ester.
Molecular and cellular biochemistry.
1995 Mar; 144(1):7-11. doi:
10.1007/bf00926734. [PMID: 7791748] - S Kobayashi, M Kasuya, K Shimizu, Y Ishii, M Takehana, K Sakai, N Suzuki, M Itoi. Glutathione isopropyl ester (YM737) inhibits the progression of X-ray-induced cataract in rats.
Current eye research.
1993 Feb; 12(2):115-22. doi:
10.3109/02713689308999479. [PMID: 8449022] - M E Anderson, A Naganuma, A Meister. Protection against cisplatin toxicity by administration of glutathione ester.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
1990 Nov; 4(14):3251-5. doi:
10.1096/fasebj.4.14.2227215. [PMID: 2227215] - S Uhlig, A Wendel. Glutathione enhancement in various mouse organs and protection by glutathione isopropyl ester against liver injury.
Biochemical pharmacology.
1990 Jun; 39(12):1877-81. doi:
10.1016/0006-2952(90)90604-j. [PMID: 2353931] - J Mårtensson, A Jain, A Meister. Glutathione is required for intestinal function.
Proceedings of the National Academy of Sciences of the United States of America.
1990 Mar; 87(5):1715-9. doi:
10.1073/pnas.87.5.1715. [PMID: 2308931]
