Glucitol-lysine (BioDeep_00000179453)
human metabolite blood metabolite
代谢物信息卡片
2-amino-6-[(2,3,4,5,6-pentahydroxyhexyl)amino]hexanoic acid
化学式: C12H26N2O7 (310.1739926)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 56.25%
分子结构信息
SMILES: C(CCNCC(C(C(C(CO)O)O)O)O)CC(C(=O)O)N
InChI: InChI=1S/C12H26N2O7/c13-7(12(20)21)3-1-2-4-14-5-8(16)10(18)11(19)9(17)6-15/h7-11,14-19H,1-6,13H2,(H,20,21)
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- L D Ghitescu, A Gugliucci, F Dumas. Actin and annexins I and II are among the main endothelial plasmalemma-associated proteins forming early glucose adducts in experimental diabetes.
Diabetes.
2001 Jul; 50(7):1666-74. doi:
10.2337/diabetes.50.7.1666. [PMID: 11423489] - T Myint, S Hoshi, T Ookawara, N Miyazawa, K Suzuki, N Taniguchi. Immunological detection of glycated proteins in normal and streptozotocin-induced diabetic rats using anti hexitol-lysine IgG.
Biochimica et biophysica acta.
1995 Oct; 1272(2):73-9. doi:
10.1016/0925-4439(95)00067-e. [PMID: 7548237] - M R Brown, T J Keith, H R Knull. Nonenzymatic incorporation of glucose and galactose into brain cytoskeletal proteins in vitro.
Neurochemistry international.
1992 Sep; 21(2):177-83. doi:
10.1016/0197-0186(92)90144-g. [PMID: 1303150] - C Ukita, M Nishikawa, A Shouzu, M Inada. Urinary excretion of glycated protein determined with a specific radioimmunoassay.
Clinical chemistry.
1991 Apr; 37(4):504-7. doi:
10.1093/clinchem/37.4.504. [PMID: 1901772] - Z Makita, H Nakayama, S Taneda, M Kato, Y Kuroda, S Aoki, K Misawa, S Nakagawa. Radioimmunoassay for the determination of glycated haemoglobin.
Diabetologia.
1991 Jan; 34(1):40-5. doi:
10.1007/bf00404023. [PMID: 1905246] - M Yano, A Mizuno, K Shima. Immunohistochemical localization of glycated protein in diabetic rat kidney.
Diabetes research and clinical practice.
1990 Mar; 8(3):215-9. doi:
10.1016/0168-8227(90)90119-e. [PMID: 2111238] - Y Yamamoto, Y Tahara, T Cha, Y Noma, M Fukuda, E Yamato, H Yoneda, F Hashimoto, C Ohboshi, M Hirota. Radioimmunoassay of glycated serum protein using monoclonal antibody to glucitollysine and coomassie-brilliant-blue-coated polystyrene beads.
Diabetes research (Edinburgh, Scotland).
1989 May; 11(1):45-9. doi:
NULL. [PMID: 2515933] - R Oste. Effect of Maillard reaction products on protein digestion.
Progress in clinical and biological research.
1989; 304(?):329-42. doi:
NULL. [PMID: 2506564] - Y Ohe, M Matsuura, Y Nakajima, S Shin, F Hashimoto, M Hirota, K Shima. Radioimmunoassay of glycosylated albumin with monoclonal antibody to glucitol-lysine.
Clinica chimica acta; international journal of clinical chemistry.
1987 Nov; 169(2-3):229-38. doi:
10.1016/0009-8981(87)90323-8. [PMID: 3123099] - H Nakayama, Z Makita, M Kato, S Taneda, H Yoshida, K Yanagisawa, S Nakagawa. Quantitative enzyme-linked immunosorbent assay (ELISA) for non-enzymatically glycated serum protein.
Journal of immunological methods.
1987 May; 99(1):95-100. doi:
10.1016/0022-1759(87)90036-6. [PMID: 3106504] - H Nakayama, S Taneda, N Manda, S Aoki, K Komori, Y Kuroda, K Misawa, S Tsushima, S Nakagawa. Radioimmunoassay for nonenzymatically glycated protein in human serum.
Clinica chimica acta; international journal of clinical chemistry.
1986 Aug; 158(3):293-9. doi:
10.1016/0009-8981(86)90294-9. [PMID: 3095001] - A R Bassiouny, H Rosenberg, G M Thiele, T L McDonald. Accelerated onset of albuminuria in diabetic rats preimmunized with glucosylated rat serum albumin.
Journal of clinical & laboratory immunology.
1985 Oct; 18(2):69-73. doi:
NULL. [PMID: 2416926] - H Nakayama, S Taneda, S Aoki, K Komori, Y Kuroda, K Misawa, S Tsushima, S Nakagawa. Antibodies to nonenzymatically glucosylated albumin in the human serum.
Biochemical and biophysical research communications.
1985 Sep; 131(2):720-5. doi:
10.1016/0006-291x(85)91297-5. [PMID: 3931639] - L K Curtiss, J L Witztum. Plasma apolipoproteins AI, AII, B, CI, and E are glucosylated in hyperglycemic diabetic subjects.
Diabetes.
1985 May; 34(5):452-61. doi:
10.2337/diab.34.5.452. [PMID: 3921419] - R Schmid, A Pollak, W Vycudilik, H Coradello, A Lischka, G Lubec. Determination of glucitollysine for the quantitation of non-enzymatic glucosylation by ion exchange chromatography and reverse phase liquid chromatography.
Clinica chimica acta; international journal of clinical chemistry.
1984 May; 139(2):119-26. doi:
10.1016/0009-8981(84)90320-6. [PMID: 6428782] - L K Curtiss, J L Witztum. A novel method for generating region-specific monoclonal antibodies to modified proteins. Application to the identification of human glucosylated low density lipoproteins.
The Journal of clinical investigation.
1983 Oct; 72(4):1427-38. doi:
10.1172/jci111099. [PMID: 6415110] - J L Witztum, U P Steinbrecher, M Fisher, A Kesaniemi. Nonenzymatic glucosylation of homologous low density lipoprotein and albumin renders them immunogenic in the guinea pig.
Proceedings of the National Academy of Sciences of the United States of America.
1983 May; 80(9):2757-61. doi:
10.1073/pnas.80.9.2757. [PMID: 6405389]