Gliadins (BioDeep_00000179435)
human metabolite blood metabolite
代谢物信息卡片
2-{[(1-{2-[({1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl}(hydroxy)methylidene)amino]-4-(C-hydroxycarbonimidoyl)butanoyl}pyrrolidin-2-yl)(hydroxy)methylidene]amino}-4-(C-hydroxycarbonimidoyl)butanoic acid
化学式: C29H41N7O9 (631.2965616)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 31.07%
分子结构信息
SMILES: C1CC(N(C1)C(=O)C(CCC(=O)N)NC(=O)C2CCCN2C(=O)C(CC3=CC=C(C=C3)O)N)C(=O)NC(CCC(=O)N)C(=O)O
InChI: InChI=1S/C29H41N7O9/c30-18(15-16-5-7-17(37)8-6-16)27(42)35-13-1-3-21(35)25(40)33-19(9-11-23(31)38)28(43)36-14-2-4-22(36)26(41)34-20(29(44)45)10-12-24(32)39/h5-8,18-22,37H,1-4,9-15,30H2,(H2,31,38)(H2,32,39)(H,33,40)(H,34,41)(H,44,45)
描述信息
Isolated from wheat flour or wheat gluten
同义名列表
10 个代谢物同义名
2-{[(1-{2-[({1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl}(hydroxy)methylidene)amino]-4-(C-hydroxycarbonimidoyl)butanoyl}pyrrolidin-2-yl)(hydroxy)methylidene]amino}-4-(C-hydroxycarbonimidoyl)butanoic acid; 2-({1-[2-({1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl}formamido)-4-carbamoylbutanoyl]pyrrolidin-2-yl}formamido)-4-carbamoylbutanoic acid; alpha-Gliadin (43-47); Gliadophorin (43-47); Tyr-pro-GLN-pro-GLN; alpha-Gliadin; alpha Gliadin; CID 17787981; Gliadins; Gliadin
数据库引用编号
7 个数据库交叉引用编号
- PubChem: 17787981
- HMDB: HMDB0252744
- Metlin: METLIN89966
- Wikipedia: Gliadin
- MeSH: Gliadin
- foodb: FDB012968
- chemspider: 15922832
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Rémy Cochereau, Hugo Voisin, Véronique Solé-Jamault, Bruno Novales, Joëlle Davy, Frédéric Jamme, Denis Renard, Adeline Boire. Influence of pH and lipid membrane on the liquid-liquid phase separation of wheat γ-gliadin in aqueous conditions.
Journal of colloid and interface science.
2024 Aug; 668(?):252-263. doi:
10.1016/j.jcis.2024.04.136. [PMID: 38678881] - Rocio Prisby, Alessandra Luchini, Lance A Liotta, Caroline Solazzo. Wheat-Based Glues in Conservation and Cultural Heritage: (Dis)solving the Proteome of Flour and Starch Pastes and Their Adhering Properties.
Journal of proteome research.
2024 May; 23(5):1649-1665. doi:
10.1021/acs.jproteome.3c00804. [PMID: 38574199] - Yuri Haneishi, Lucia Treppiccione, Francesco Maurano, Diomira Luongo, Junki Miyamoto, Mauro Rossi. High Fat Diet-Wheat Gliadin Interaction and its Implication for Obesity and Celiac Disease Onset: In Vivo Studies.
Molecular nutrition & food research.
2024 May; 68(9):e2300779. doi:
10.1002/mnfr.202300779. [PMID: 38632845] - Zitong Yu, Ural Yunusbaev, Allan Fritz, Michael Tilley, Alina Akhunova, Harold Trick, Eduard Akhunov. CRISPR-based editing of the ω- and γ-gliadin gene clusters reduces wheat immunoreactivity without affecting grain protein quality.
Plant biotechnology journal.
2024 Apr; 22(4):892-903. doi:
10.1111/pbi.14231. [PMID: 37975410] - Ricardo Dias, Sara da Silva, Bruna Monteiro, Rosa Pérez-Gregorio, Nuno Mateus, Carmen Gianfrani, Maria Vittoria Barone, Petr Martinek, Victor Freitas. Mass spectrometry-based quantification of immunostimulatory gliadin proteins and peptides in coloured wheat varieties: Implications for Celiac Disease.
Food research international (Ottawa, Ont.).
2024 Feb; 178(?):114008. doi:
10.1016/j.foodres.2024.114008. [PMID: 38309890] - Mingxi Liu, Shuhan Dai, Lijun Yin, Zhijie Huang, Xin Jia. Wheat Gluten Deamidation: Structure, Allergenicity and Its Application in Hypoallergenic Noodles.
Journal of the science of food and agriculture.
2023 Nov; ?(?):. doi:
10.1002/jsfa.13133. [PMID: 37968892] - Jiaojiao Li, Jiachuang Li, Lei Li, Linrun Xiang, Li Zhao, Jinke Liu, Shuhui Liu, Qunhui Yang, Jun Wu, Xinhong Chen. Effect of gliadin from Psathrostachys huashanica on dough rheological properties and biscuit quality.
Food chemistry.
2023 Nov; 425(?):136537. doi:
10.1016/j.foodchem.2023.136537. [PMID: 37290239] - Serena Carpentieri, Giovanna Ferrari, Francesco Donsì. All-natural wheat gliadin-gum arabic nanocarriers for encapsulation and delivery of grape by-products phenolics obtained through different extraction procedures.
Food chemistry.
2023 Oct; 424(?):136385. doi:
10.1016/j.foodchem.2023.136385. [PMID: 37247597] - Carol López-de-Dicastillo, Joaquín Gómez-Estaca, Gracia López-Carballo, Rafael Gavara, Pilar Hernández-Muñoz. Agro-Industrial Protein Waste and Co-Products Valorization for the Development of Bioplastics: Thermoprocessing and Characterization of Feather Keratin/Gliadin Blends.
Molecules (Basel, Switzerland).
2023 Oct; 28(21):. doi:
10.3390/molecules28217350. [PMID: 37959768] - Valentina Faihs, Claudia Kugler, Viktoria Schmalhofer, Katharina Anne Scherf, Barbara Lexhaller, Charlotte G Mortz, Carsten Bindslev-Jensen, Tilo Biedermann, Knut Brockow. Wheat-dependent exercise-induced anaphylaxis: subtypes, diagnosis, and management.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.
2023 10; 21(10):1131-1135. doi:
10.1111/ddg.15162. [PMID: 37462335] - Dan Liu, Huaimao Yang, Zhaoheng Zhang, Qian Chen, Weilong Guo, Vincenzo Rossi, Mingming Xin, Jinkun Du, Zhaorong Hu, Jie Liu, Huiru Peng, Zhongfu Ni, Qixin Sun, Yingyin Yao. An elite γ-gliadin allele improves end-use quality in wheat.
The New phytologist.
2023 07; 239(1):87-101. doi:
10.1111/nph.18722. [PMID: 36617723] - Frederik Janssen, Viena Monterde, Arno G B Wouters. Relevance of the air-water interfacial and foaming properties of (modified) wheat proteins for food systems.
Comprehensive reviews in food science and food safety.
2023 05; 22(3):1517-1554. doi:
10.1111/1541-4337.13120. [PMID: 36815740] - Sewon Kim, Jae-Ryeong Sim, Yong Q Gu, Susan B Altenbach, Sandra Denery-Papini, Florence Pineau, Olivier Tranquet, Yu-Jeong Yang, Eun Ji Park, Sun-Hyung Lim, Chon-Sik Kang, Changhyun Choi, Jong-Yeol Lee. Toward reducing the immunogenic potential of wheat flour: identification and characterization of wheat lines missing omega-5 gliadins encoded by the 1D chromosome.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik.
2023 Mar; 136(3):33. doi:
10.1007/s00122-023-04295-0. [PMID: 36897507] - Eishin Morita, Yuko Chinuki, Kunie Kohno, Hiroaki Matsuo. Cofactors of wheat-dependent exercise-induced anaphylaxis increase gastrointestinal gliadin absorption by an inhibition of prostaglandin production.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2023 03; 53(3):359-361. doi:
10.1111/cea.14265. [PMID: 36536534] - Jameel M Al-Khayri, Khairiah M Alwutayd, Fatmah A Safhi, Mesfer M Alqahtani, Rana M Alshegaihi, Diaa Abd El-Moneim, Shri Mohan Jain, Ahmed S Eldomiaty, Rahma Alshamrani, Amani Omar Abuzaid, Abdallah A Hassanin. Assessment of intra- and inter-genetic diversity in tetraploid and hexaploid wheat genotypes based on omega, gamma and alpha-gliadin profiles.
PeerJ.
2023; 11(?):e16330. doi:
10.7717/peerj.16330. [PMID: 37953773] - Shivangi Puja, Shreya Seth, Rachna Hora, Satinder Kaur, Prakash Chandra Mishra. Understanding the Molecular Basis for Enhanced Glutenase Activity of Actinidin using Structural Bioinformatics.
Protein and peptide letters.
2023; 30(9):777-782. doi:
10.2174/0929866530666230817141100. [PMID: 37592795] - Susane Trevisan, Ali Salimi Khorshidi, Martin G Scanlon. Relationship between nitrogen functionality and wheat flour dough rheology: Extensional and shear approaches.
Food research international (Ottawa, Ont.).
2022 12; 162(Pt B):112049. doi:
10.1016/j.foodres.2022.112049. [PMID: 36461313] - Baraa Rehamnia, Natuschka M Lee, Ramune Kuktaite, Noreddine Kacem Chaouche. Screening of Spore-Forming Bacteria with Probiotic Potential in Pristine Algerian Caves.
Microbiology spectrum.
2022 10; 10(5):e0024822. doi:
10.1128/spectrum.00248-22. [PMID: 36214685] - Walburga Dieterich, Charlotte Schuster, Paulina Gundel, Katharina A Scherf, Darina Pronin, Sabrina Geisslitz, Andreas Börner, Markus F Neurath, Yurdagül Zopf. Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS.
Nutrients.
2022 Oct; 14(20):. doi:
10.3390/nu14204257. [PMID: 36296938] - Iwona Stawoska, Jacek Waga, Aleksandra Wesełucha-Birczyńska, Michał Dziurka, Grażyna Podolska, Edyta Aleksandrowicz, Andrzej Skoczowski. Does Nitrogen Fertilization Affect the Secondary Structures of Gliadin Proteins in Hypoallergenic Wheat?.
Molecules (Basel, Switzerland).
2022 Sep; 27(17):. doi:
10.3390/molecules27175684. [PMID: 36080452] - Knut Brockow, Klara Reidenbach, Claudia Kugler, Tilo Biedermann. Wheat-dependent exercise-induced anaphylaxis caused by percutaneous sensitisation to hydrolysed wheat protein in cosmetics.
Contact dermatitis.
2022 09; 87(3):296-297. doi:
10.1111/cod.14144. [PMID: 35524944] - Frederik Janssen, Eline Mesure, Arno G B Wouters. Relating the protein composition and air-water interfacial properties of aqueous flour extracts from wheats grown at different nitrogen fertilization levels.
Food chemistry.
2022 Aug; 386(?):132831. doi:
10.1016/j.foodchem.2022.132831. [PMID: 35509165] - Ziqi Guo, Yuqi Huang, Jian Huang, Shuyi Li, Zhenzhou Zhu, Qianchun Deng, Shuiyuan Cheng. Formation of protein-anthocyanin complex induced by grape skin extracts interacting with wheat gliadins: Multi-spectroscopy and molecular docking analysis.
Food chemistry.
2022 Aug; 385(?):132702. doi:
10.1016/j.foodchem.2022.132702. [PMID: 35313199] - Laura Del Amo-Maestro, Soraia R Mendes, Arturo Rodríguez-Banqueri, Laura Garzon-Flores, Marina Girbal, María José Rodríguez-Lagunas, Tibisay Guevara, Àngels Franch, Francisco J Pérez-Cano, Ulrich Eckhard, F Xavier Gomis-Rüth. Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy.
Nature communications.
2022 08; 13(1):4446. doi:
10.1038/s41467-022-32215-1. [PMID: 35915115] - Tiew-Yik Ting, Anis Baharin, Ahmad Bazli Ramzi, Chyan-Leong Ng, Hoe-Han Goh. Neprosin belongs to a new family of glutamic peptidase based on in silico evidence.
Plant physiology and biochemistry : PPB.
2022 Jul; 183(?):23-35. doi:
10.1016/j.plaphy.2022.04.027. [PMID: 35537348] - Joel Markgren, Faiza Rasheed, Mikael S Hedenqvist, Marie Skepö, Eva Johansson. Clustering and cross-linking of the wheat storage protein α-gliadin: A combined experimental and theoretical approach.
International journal of biological macromolecules.
2022 Jun; 211(?):592-615. doi:
10.1016/j.ijbiomac.2022.05.032. [PMID: 35577195] - Qian Chen, Changfeng Yang, Zhaoheng Zhang, Zihao Wang, Yongming Chen, Vincenzo Rossi, Wei Chen, Mingming Xin, Zhenqi Su, Jinkun Du, Weilong Guo, Zhaorong Hu, Jie Liu, Huiru Peng, Zhongfu Ni, Qixin Sun, Yingyin Yao. Unprocessed wheat γ-gliadin reduces gluten accumulation associated with the endoplasmic reticulum stress and elevated cell death.
The New phytologist.
2022 Jun; ?(?):. doi:
10.1111/nph.18316. [PMID: 35714031] - Silvia Trasciatti, Francesca Piras, Silvano Bonaretti, Sandra Marini, Simona Nencioni, Elena Biasci, Colin Gerard Egan, Fabrizio Nannipieri. Effect of oral cholecalciferol in a murine model of celiac disease: A dose ranging study.
The Journal of steroid biochemistry and molecular biology.
2022 06; 220(?):106083. doi:
10.1016/j.jsbmb.2022.106083. [PMID: 35257869] - Bing Jiang, Qiaorun Zhao, Honghong Shan, Ying Guo, Xiao Xu, David Julian McClements, Chongjiang Cao, Biao Yuan. Impact of Heat Treatment on the Structure and Properties of the Plant Protein Corona Formed around TiO2 Nanoparticles.
Journal of agricultural and food chemistry.
2022 Jun; 70(21):6540-6551. doi:
10.1021/acs.jafc.2c01650. [PMID: 35584036] - Safa Ambusaidi, Al Manar Al Busaidi, Asma Al Salmani, Robin Davidson, Jalila Alshekaili, Mahmood Al Kindi, Rahma Al Kindi. Prevalence of Coeliac Disease in Omani Adults with Iron Deficiency Anaemia of Unknown Cause: Case-finding study.
Sultan Qaboos University medical journal.
2022 May; 22(2):262-267. doi:
10.18295/squmj.5.2021.101. [PMID: 35673297] - Xuemin Kang, Jie Sui, Xiaolei Zhang, Gao Wei, Bin Wang, Pengfei Liu, Lizhong Qiu, Hossny A El-Banna, Bo Cui, A M Abd El-Aty. The impact of gliadin and glutenin on the formation and structure of starch-lipid complexes.
Food chemistry.
2022 Mar; 371(?):131095. doi:
10.1016/j.foodchem.2021.131095. [PMID: 34537618] - Ádám Diós, Bharani Srinivasan, Judit Gyimesi, Katharina Werkstetter, Rudolf Valenta, Sibylle Koletzko, Ilma R Korponay-Szabó. Changes in Non-Deamidated versus Deamidated Epitope Targeting and Disease Prediction during the Antibody Response to Gliadin and Transglutaminase of Infants at Risk for Celiac Disease.
International journal of molecular sciences.
2022 Feb; 23(5):. doi:
10.3390/ijms23052498. [PMID: 35269639] - Zhengfu Zhou, Congcong Liu, Maomao Qin, Wenxu Li, Jinna Hou, Xia Shi, Ziju Dai, Wen Yao, Baoming Tian, Zhensheng Lei, Yang Li, Zhengqing Wu. Promoter DNA hypermethylation of TaGli-γ-2.1 positively regulates gluten strength in bread wheat.
Journal of advanced research.
2022 02; 36(?):163-173. doi:
10.1016/j.jare.2021.06.021. [PMID: 35127171] - Elide Anna Pastorello, Alessandro Toscano, Giuseppe Scibilia, Chrysi Stafylaraki, Carlo Maria Rossi, Linda Borgonovo, Michele Nichelatti, Laura Farioli. Clinical Features of Wheat Allergy Are Significantly Different between Tri a 14 Sensitized Patients and Tri a 19 Sensitized Ones.
International archives of allergy and immunology.
2022; 183(6):591-599. doi:
10.1159/000520936. [PMID: 34929709] - Zhirong Du, Jia Yin. Safety of an inactivated COVID-19 vaccine in patients with - wheat-dependent exercise-induced anaphylaxis.
Allergologia et immunopathologia.
2022; 50(3):132-137. doi:
10.1016/j.iac.2014.04.004. [PMID: 35527667] - María H Guzmán-López, Susana Sánchez-León, Miriam Marín-Sanz, Isabel Comino, Verónica Segura, Luis Vaquero, Octavio M Rivero-Lezcano, Jorge Pastor, Carolina Sousa, Santiago Vivas, Francisco Barro. Oral Consumption of Bread from an RNAi Wheat Line with Strongly Silenced Gliadins Elicits No Immunogenic Response in a Pilot Study with Celiac Disease Patients.
Nutrients.
2021 Dec; 13(12):. doi:
10.3390/nu13124548. [PMID: 34960101] - María H Guzmán-López, Miriam Marín-Sanz, Susana Sánchez-León, Francisco Barro. A Bioinformatic Workflow for InDel Analysis in the Wheat Multi-Copy α-Gliadin Gene Family Engineered with CRISPR/Cas9.
International journal of molecular sciences.
2021 Dec; 22(23):. doi:
10.3390/ijms222313076. [PMID: 34884880] - Monika Rani, Dalbir Singh Sogi, Balmeet Singh Gill. Characterization of gliadin, secalin and hordein fractions using analytical techniques.
Scientific reports.
2021 11; 11(1):23135. doi:
10.1038/s41598-021-02099-0. [PMID: 34848764] - Wan Yan Zhou, Xiu Ying Liu, Ming Ming Wang, Li Ping Liang, Le Liu, De Kai Zheng, Jocelyn A Silvester, Wen Jun Ma, Wei Wu, Gui Yuan Ji, Yan Jun Xu, Xiao Jun Xu, Ciarán P Kelly, Ye Chen. Prevalence of celiac disease in China: Meta-analysis and serological survey in high-risk populations.
Journal of digestive diseases.
2021 Nov; 22(11):645-655. doi:
10.1111/1751-2980.13049. [PMID: 34482631] - Roberta Paris, Giuseppe Petruzzino, Michele Savino, Vanessa De Simone, Donatella B M Ficco, Daniela Trono. Genome-Wide Identification, Characterization and Expression Pattern Analysis of the γ-Gliadin Gene Family in the Durum Wheat (Triticum durum Desf.) Cultivar Svevo.
Genes.
2021 10; 12(11):. doi:
10.3390/genes12111743. [PMID: 34828349] - Gunhild Alvik Nyborg, Øyvind Molberg. Small intestinal biopsy findings consistent with celiac disease in patients with idiopathic inflammatory myopathy: Review of existing literature.
Seminars in arthritis and rheumatism.
2021 10; 51(5):1033-1044. doi:
10.1016/j.semarthrit.2021.07.012. [PMID: 34416625] - Fedia Baba-Ahmed, Kamilia Guedri, Fouzia Trea, Kheireddine Ouali. Protective role of a melon superoxide dismutase combined with gliadin (GliSODin) on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis.
Journal of cancer research and therapeutics.
2021 Oct; 17(6):1445-1453. doi:
10.4103/jcrt.jcrt_175_19. [PMID: 34916376] - Iwona Stawoska, Aleksandra Wesełucha-Birczyńska, Andrzej Skoczowski, Michał Dziurka, Jacek Waga. FT-Raman Spectroscopy as a Tool to Study the Secondary Structures of Wheat Gliadin Proteins.
Molecules (Basel, Switzerland).
2021 Sep; 26(17):. doi:
10.3390/molecules26175388. [PMID: 34500820] - Chiara Maria Trovato, Monica Montuori, Nicoletta Pietropaoli, Salvatore Oliva. COVID-19 and celiac disease: A pathogenetic hypothesis for a celiac outbreak.
International journal of clinical practice.
2021 Sep; 75(9):e14452. doi:
10.1111/ijcp.14452. [PMID: 34145702] - Guangxin Feng, Kaining Han, Yanlei Li, Qian Yang, Weiting Feng, Jinmei Wang, Xiaoquan Yang. Undigestible Gliadin Peptide Nanoparticles Penetrate Mucus and Reduce Mucus Production Driven by Intestinal Epithelial Cell Damage.
Journal of agricultural and food chemistry.
2021 Jul; 69(28):7979-7989. doi:
10.1021/acs.jafc.1c02177. [PMID: 34251199] - Ádám Diós, Rita Elek, Ildikó Szabó, Szilvia Horváth, Judit Gyimesi, Róbert Király, Katharina Werkstetter, Sibylle Koletzko, László Fésüs, Ilma R Korponay-Szabó. Gamma-gliadin specific celiac disease antibodies recognize p31-43 and p57-68 alpha gliadin peptides in deamidation related manner as a result of cross-reaction.
Amino acids.
2021 Jul; 53(7):1051-1063. doi:
10.1007/s00726-021-03006-7. [PMID: 34059947] - Magdalena Kraft, Sabine Dölle-Bierke, Jean-Marie Renaudin, Franziska Ruëff, Kathrin Scherer Hofmeier, Regina Treudler, Claudia Pföhler, Thomas Hawranek, Iwona Poziomkowska-Gęsicka, Uta Jappe, George Christoff, Sabine Müller, Montserrat Fernandez-Rivas, Blanca E García, Talía M De Vicente Jiménez, Victoria Cardona, Andreas Kleinheinz, Burkhard Kreft, Andrea Bauer, Nicola Wagner, Bettina Wedi, Markus Wenzel, Maria Beatrice Bilò, Margitta Worm. Wheat Anaphylaxis in Adults Differs from Reactions to Other Types of Food.
The journal of allergy and clinical immunology. In practice.
2021 07; 9(7):2844-2852.e5. doi:
10.1016/j.jaip.2021.03.037. [PMID: 33831620] - Parisa Esmaeili, Elham Rostami, Arefeh Akbarijavar, Alireza Akbari Meyestani, Hamed Bashiri, Mohammad Ali Rezaee, Shohreh Fakhari. Effects of Gliadin on Autoimmune Responses of Central Nervous System of C57BL/6 Mice.
Iranian journal of allergy, asthma, and immunology.
2021 Apr; 20(2):188-197. doi:
. [PMID: 33904677] - Jan G Schaart, Elma M J Salentijn, Svetlana V Goryunova, Charity Chidzanga, Danny G Esselink, Nick Gosman, Alison R Bentley, Luud J W J Gilissen, Marinus J M Smulders. Exploring the alpha-gliadin locus: the 33-mer peptide with six overlapping coeliac disease epitopes in Triticum aestivum is derived from a subgroup of Aegilops tauschii.
The Plant journal : for cell and molecular biology.
2021 04; 106(1):86-94. doi:
10.1111/tpj.15147. [PMID: 33369792] - Sanja Petronijevic, Solveig Stig, Trond S Halstensen. Epitope mapping of anti-amelogenin IgG in untreated celiac children.
European journal of oral sciences.
2021 04; 129(2):e12770. doi:
10.1111/eos.12770. [PMID: 33656197] - Yu Wang, Juan Sun, Lamei Xue, Jinxin Liu, Chenzhipeng Nie, Mingcong Fan, Haifeng Qian, Duo Zhang, Hao Ying, Yan Li, Li Wang. l-Arabinose Attenuates Gliadin-Induced Food Allergy via Regulation of Th1/Th2 Balance and Upregulation of Regulatory T Cells in Mice.
Journal of agricultural and food chemistry.
2021 Mar; 69(12):3638-3646. doi:
10.1021/acs.jafc.0c07167. [PMID: 33734700] - Daxing Wen, Haicheng Xu, Mingrong He, Chunqing Zhang. Proteomic analysis of wheat seeds produced under different nitrogen levels before and after germination.
Food chemistry.
2021 Mar; 340(?):127937. doi:
10.1016/j.foodchem.2020.127937. [PMID: 32889215] - Juan Pablo Stefanolo, Martín Tálamo, Samanta Dodds, María de la Paz Temprano, Ana Florencia Costa, María Laura Moreno, María Inés Pinto-Sánchez, Edgardo Smecuol, Horacio Vázquez, Andrea Gonzalez, Sonia Isabel Niveloni, Eduardo Mauriño, Elena F Verdu, Julio César Bai. Real-World Gluten Exposure in Patients With Celiac Disease on Gluten-Free Diets, Determined From Gliadin Immunogenic Peptides in Urine and Fecal Samples.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
2021 03; 19(3):484-491.e1. doi:
10.1016/j.cgh.2020.03.038. [PMID: 32217152] - Darina Pronin, Andreas Börner, Katharina Anne Scherf. Old and modern wheat (Triticum aestivum L.) cultivars and their potential to elicit celiac disease.
Food chemistry.
2021 Mar; 339(?):127952. doi:
10.1016/j.foodchem.2020.127952. [PMID: 33152854] - Eugene Metakovsky, Laura Pascual, Patrizia Vaccino, Viktor Melnik, Marta Rodriguez-Quijano, Yulia Popovych, Sabina Chebotar, William John Rogers. Heteroalleles in Common Wheat: Multiple Differences between Allelic Variants of the Gli-B1 Locus.
International journal of molecular sciences.
2021 Feb; 22(4):. doi:
10.3390/ijms22041832. [PMID: 33673225] - Olivia Ogilvie, Sarah Roberts, Kevin Sutton, Juliet Gerrard, Nigel Larsen, Laura Domigan. The effect of baking time and temperature on gluten protein structure and celiac peptide digestibility.
Food research international (Ottawa, Ont.).
2021 02; 140(?):109988. doi:
10.1016/j.foodres.2020.109988. [PMID: 33648223] - Haiqiang Chen, Shijin Li, Yongwei Liu, Junxian Liu, Xiaolan Ma, Lipu Du, Ke Wang, Xingguo Ye. Effects of 1Dy12 subunit silencing on seed storage protein accumulation and flour-processing quality in a common wheat somatic variation line.
Food chemistry.
2021 Jan; 335(?):127663. doi:
10.1016/j.foodchem.2020.127663. [PMID: 32738540] - Silvia Voci, Massimo Fresta, Donato Cosco. Gliadins as versatile biomaterials for drug delivery applications.
Journal of controlled release : official journal of the Controlled Release Society.
2021 01; 329(?):385-400. doi:
10.1016/j.jconrel.2020.11.048. [PMID: 33278484] - Sho Hayashida, Takashi Murakami, Sho Tsuyama, Tsutomu Takeda, Hiroya Ueyama, Kenshi Matsumoto, Tomoyoshi Shibuya, Mariko Hojo, Takashi Yao, Akihito Nagahara. [Celiac disease:a case report detailing clinical and pathological improvement with a gluten-free diet].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.
2021; 118(7):661-670. doi:
10.11405/nisshoshi.118.661. [PMID: 34248079] - Christian B Lindstad, Alisa E Dewan, Jorunn Stamnaes, Ludvig M Sollid, M Fleur du Pré. TG2-gluten complexes as antigens for gluten-specific and transglutaminase-2 specific B cells in celiac disease.
PloS one.
2021; 16(11):e0259082. doi:
10.1371/journal.pone.0259082. [PMID: 34731200] - Yu Chen, Ying Liang, Feng Jia, Di Chen, Xia Zhang, Qi Wang, Jinshui Wang. Effect of extrusion temperature on the protein aggregation of wheat gluten with the addition of peanut oil during extrusion.
International journal of biological macromolecules.
2021 Jan; 166(?):1377-1386. doi:
10.1016/j.ijbiomac.2020.11.017. [PMID: 33161084] - Francesca Truzzi, Camilla Tibaldi, Anne Whittaker, Silvia Dilloo, Enzo Spisni, Giovanni Dinelli. Pro-Inflammatory Effect of Gliadins and Glutenins Extracted from Different Wheat Cultivars on an In Vitro 3D Intestinal Epithelium Model.
International journal of molecular sciences.
2020 Dec; 22(1):. doi:
10.3390/ijms22010172. [PMID: 33375311] - Darina Pronin, Andreas Börner, Hans Weber, Katharina Anne Scherf. Wheat (Triticum aestivum L.) Breeding from 1891 to 2010 Contributed to Increasing Yield and Glutenin Contents but Decreasing Protein and Gliadin Contents.
Journal of agricultural and food chemistry.
2020 Nov; 68(46):13247-13256. doi:
10.1021/acs.jafc.0c02815. [PMID: 32648759] - Niharika Dhattarwal, Vikram K Mahajan, Karaninder S Mehta, Pushpinder S Chauhan, Rajinder S Yadav, Satya Bhushan Sharma, Anuj Sharma, Reena Sharma, Ashwani Rana, Megha Sondhi. The association of anti-gliadin and anti-transglutaminase antibodies and chronic plaque psoriasis in Indian patients: Preliminary results of a descriptive cross-sectional study.
The Australasian journal of dermatology.
2020 Nov; 61(4):e378-e382. doi:
10.1111/ajd.13308. [PMID: 32397002] - Silvia Fernández-Pérez, Jenifer Pérez-Andrés, Sergio Gutiérrez, Nicolás Navasa, Honorina Martínez-Blanco, Miguel Ángel Ferrero, Santiago Vivas, Luis Vaquero, Cristina Iglesias, Javier Casqueiro, Leandro B Rodríguez-Aparicio. The Human Digestive Tract Is Capable of Degrading Gluten from Birth.
International journal of molecular sciences.
2020 Oct; 21(20):. doi:
10.3390/ijms21207696. [PMID: 33080976] - Line Lund Kårhus, Tea Skaaby, Janne Petersen, Anja Lykke Madsen, Betina Heinsbæk Thuesen, Peter Schwarz, Jüri J Rumessen, Allan Linneberg. Long-term Consequences of Undiagnosed Celiac Seropositivity.
The American journal of gastroenterology.
2020 10; 115(10):1681-1688. doi:
10.14309/ajg.0000000000000737. [PMID: 32558687] - Giulia N Catassi, Martina Vallorani, Federica Cerioni, Elena Lionetti, Carlo Catassi. A negative fallout of COVID-19 lockdown in Italy: Life-threatening delay in the diagnosis of celiac disease.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2020 10; 52(10):1092-1093. doi:
10.1016/j.dld.2020.05.016. [PMID: 32425730] - Mohammed M Mehanna, Amina Tarek Mneimneh. Updated but not outdated 'Gliadin': A plant protein in advanced pharmaceutical nanotechnologies.
International journal of pharmaceutics.
2020 Sep; 587(?):119672. doi:
10.1016/j.ijpharm.2020.119672. [PMID: 32739392] - E Cristina Peláez, M-Carmen Estevez, Remedios Domínguez, Carolina Sousa, Angel Cebolla, Laura M Lechuga. A compact SPR biosensor device for the rapid and efficient monitoring of gluten-free diet directly in human urine.
Analytical and bioanalytical chemistry.
2020 Sep; 412(24):6407-6417. doi:
10.1007/s00216-020-02616-6. [PMID: 32333077] - Amelia Torcello-Gómez, Didier Dupont, Julien Jardin, Valérie Briard-Bion, Amélie Deglaire, Kerstin Risse, Elodie Mechoulan, Alan Mackie. Human gastrointestinal conditions affect in vitro digestibility of peanut and bread proteins.
Food & function.
2020 Aug; 11(8):6921-6932. doi:
10.1039/d0fo01451f. [PMID: 32691795] - Katarzyna Gładyś, Jolanta Dardzińska, Marek Guzek, Krystian Adrych, Sylwia Małgorzewicz. Celiac Dietary Adherence Test and Standardized Dietician Evaluation in Assessment of Adherence to a Gluten-Free Diet in Patients with Celiac Disease.
Nutrients.
2020 Jul; 12(8):. doi:
10.3390/nu12082300. [PMID: 32751809] - Joel Markgren, Mikael Hedenqvist, Faiza Rasheed, Marie Skepö, Eva Johansson. Glutenin and Gliadin, a Piece in the Puzzle of their Structural Properties in the Cell Described through Monte Carlo Simulations.
Biomolecules.
2020 07; 10(8):. doi:
10.3390/biom10081095. [PMID: 32717949] - Zhirong Du, Xiang Gao, Jia Yin. Gut microbiome alterations in patients with wheat-dependent exercise-induced anaphylaxis.
International immunopharmacology.
2020 Jul; 84(?):106557. doi:
10.1016/j.intimp.2020.106557. [PMID: 32388491] - Punchama Pacharn, Nunthana Siripipattanamongkol, Nittida Pannakapitak, Nualanong Visitsunthorn, Orathai Jirapongsananuruk, Surapon Piboonpocanun, Pakit Vichyanond. Accuracy of in-house alcohol-dissolved wheat extract for diagnosing IgE-mediated wheat allergy.
Asian Pacific journal of allergy and immunology.
2020 Jun; 38(2):102-107. doi:
10.12932/ap-140218-0265. [PMID: 30447656] - Olha Lakhneko, Maksym Danchenko, Bogdan Morgun, Andrej Kováč, Petra Majerová, Ľudovit Škultéty. Comprehensive Comparison of Clinically Relevant Grain Proteins in Modern and Traditional Bread Wheat Cultivars.
International journal of molecular sciences.
2020 May; 21(10):. doi:
10.3390/ijms21103445. [PMID: 32414116] - Tobias L Freitag, Joseph R Podojil, Ryan M Pearson, Frank J Fokta, Cecilia Sahl, Marcel Messing, Leif C Andersson, Katarzyna Leskinen, Päivi Saavalainen, Lisa I Hoover, Kelly Huang, Deborah Phippard, Sanaz Maleki, Nicholas J C King, Lonnie D Shea, Stephen D Miller, Seppo K Meri, Daniel R Getts. Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease.
Gastroenterology.
2020 05; 158(6):1667-1681.e12. doi:
10.1053/j.gastro.2020.01.045. [PMID: 32032584] - Ken-Ichi Nagakura, Noriyuki Yanagida, Sakura Sato, Makoto Nishino, Kyohei Takahashi, Tomoyuki Asaumi, Kiyotake Ogura, Motohiro Ebisawa. Low-dose-oral immunotherapy for children with wheat-induced anaphylaxis.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.
2020 05; 31(4):371-379. doi:
10.1111/pai.13220. [PMID: 31976576] - Lilia Abbad, Renato C Monteiro, Laureline Berthelot. Food antigens and Transglutaminase 2 in IgA nephropathy: Molecular links between gut and kidney.
Molecular immunology.
2020 05; 121(?):1-6. doi:
10.1016/j.molimm.2020.02.019. [PMID: 32135400] - Yuko Chinuki, Akiko Yagami, Atsuko Adachi, Kayoko Matsunaga, Tsukasa Ugajin, Hiroo Yokozeki, Misa Hayashi, Ichiro Katayama, Kunie Kohno, Kuninori Shiwaku, Eishin Morita. In vitro basophil activation is reduced by short-term omalizumab treatment in hydrolyzed wheat protein allergy.
Allergology international : official journal of the Japanese Society of Allergology.
2020 Apr; 69(2):284-286. doi:
10.1016/j.alit.2019.09.006. [PMID: 31753713] - E M Domsa, G A Filip, D Olteanu, I Baldea, S Clichici, A Muresan, L David, B Moldovan, I Para, M Suciu, M Achim, V Negrean, V Andreica. Gold nanoparticles phytoreduced with Cornus mas extract mitigate some of gliadin effects on Caco-2 cells.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2020 Apr; 71(2):. doi:
10.26402/jpp.2020.2.04. [PMID: 32633238] - Jingyi Qiu, Yulin Yuan, Yaxi Li, Christopher Haley, Uyen Ngoc Mui, Ritu Swali, Chandra Mohan, Stephen K Tyring, Tianfu Wu. Discovery of IgG4 Anti-Gliadin Autoantibody as a Potential Biomarker of Psoriasis Using an Autoantigen Array.
Proteomics. Clinical applications.
2020 03; 14(2):e1800114. doi:
10.1002/prca.201800114. [PMID: 31671471] - Yuto Hamada, Yuko Chinuki, Yuma Fukutomi, Eiji Nakatani, Akiko Yagami, Kayoko Matsunaga, Yoshiko Oda, Atsushi Fukunaga, Atsuko Adachi, Makiko Hiragun, Michihiro Hide, Eishin Morita. Long-term dynamics of omega-5 gliadin-specific IgE levels in patients with adult-onset wheat allergy.
The journal of allergy and clinical immunology. In practice.
2020 03; 8(3):1149-1151.e3. doi:
10.1016/j.jaip.2019.10.008. [PMID: 31678299] - Antonella Orlando, Guglielmina Chimienti, Angela Maria Serena Lezza, Vito Pesce, Isabella Gigante, Benedetta D'Attoma, Francesco Russo. Lactobacillus Rhamnosus GG Affects the BDNF System in Brain Samples of Wistar Rats with Pepsin-Trypsin-Digested Gliadin (PTG)-Induced Enteropathy.
Nutrients.
2020 Feb; 12(3):. doi:
10.3390/nu12030629. [PMID: 32120967] - Fusheng Sun, Xiaoxue Xie, Yufan Zhang, Jiangwei Duan, Mingyu Ma, Yaqiong Wang, Ding Qiu, Xinpei Lu, Guangxiao Yang, Guangyuan He. Effects of Cold Jet Atmospheric Pressure Plasma on the Structural Characteristics and Immunoreactivity of Celiac-Toxic Peptides and Wheat Storage Proteins.
International journal of molecular sciences.
2020 Feb; 21(3):. doi:
10.3390/ijms21031012. [PMID: 32033029] - Y-Q Zhu, D-Q Wang, B Liu, Y Hu, Y-Y Shen, J-H Xu, H Tang. Wheat-dependent exercise-induced anaphylaxis in Chinese people: a clinical research on 33 cases with antigenic analysis of wheat proteins.
Clinical and experimental dermatology.
2020 Jan; 45(1):56-62. doi:
10.1111/ced.14035. [PMID: 31267575] - Steffen Husby, Sibylle Koletzko, Ilma Korponay-Szabó, Kalle Kurppa, Maria Luisa Mearin, Carmen Ribes-Koninckx, Raanan Shamir, Riccardo Troncone, Renata Auricchio, Gemma Castillejo, Robin Christensen, Jernej Dolinsek, Peter Gillett, Asbjørn Hróbjartsson, Tunde Koltai, Markku Maki, Sabrina Mai Nielsen, Alina Popp, Ketil Størdal, Katharina Werkstetter, Margreet Wessels. European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020.
Journal of pediatric gastroenterology and nutrition.
2020 01; 70(1):141-156. doi:
10.1097/mpg.0000000000002497. [PMID: 31568151] - Susan B Altenbach, Han-Chang Chang, Annamaria Simon-Buss, Toni Mohr, Naxin Huo, Yong Q Gu. Exploiting the reference genome sequence of hexaploid wheat: a proteomic study of flour proteins from the cultivar Chinese Spring.
Functional & integrative genomics.
2020 Jan; 20(1):1-16. doi:
10.1007/s10142-019-00694-z. [PMID: 31250230] - Nathalie Geneix, Michèle Dalgalarrondo, Caroline Tassy, Isabelle Nadaud, Pierre Barret, Bénédicte Bakan, Khalil Elmorjani, Didier Marion. Relationships between puroindoline A-prolamin interactions and wheat grain hardness.
PloS one.
2020; 15(9):e0225293. doi:
10.1371/journal.pone.0225293. [PMID: 32991576] - Marios Hadjivassiliou, Iain D Croall, Panagiotis Zis, Ptolemaios G Sarrigiannis, David S Sanders, Pascale Aeschlimann, Richard A Grünewald, Paul A Armitage, Daniel Connolly, Daniel Aeschlimann, Nigel Hoggard. Neurologic Deficits in Patients With Newly Diagnosed Celiac Disease Are Frequent and Linked With Autoimmunity to Transglutaminase 6.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
2019 12; 17(13):2678-2686.e2. doi:
10.1016/j.cgh.2019.03.014. [PMID: 30885888] - Mengfei Li, Xiong Deng, Xuexin Xu, Nannan Liu, Zhimin Wang, Yueming Yan. Effects of water deficit and different nitrogen fertilizer treatments on the quality of wheat for Chinese fresh white noodles and steamed bread and the composition of storage proteins.
Journal of the science of food and agriculture.
2019 Nov; 99(14):6431-6443. doi:
10.1002/jsfa.9922. [PMID: 31294831] - Naxin Huo, Tingting Zhu, Shengli Zhang, Toni Mohr, Ming-Cheng Luo, Jong-Yeol Lee, Assaf Distelfeld, Susan Altenbach, Yong Q Gu. Rapid evolution of α-gliadin gene family revealed by analyzing Gli-2 locus regions of wild emmer wheat.
Functional & integrative genomics.
2019 Nov; 19(6):993-1005. doi:
10.1007/s10142-019-00686-z. [PMID: 31197605] - Akiko Sugiyama, Reiko Kishikawa, Satoshi Honjo, Haruko Nishie, Tomoaki Iwanaga, Masutaka Furue. Anti-gluten IgE titer is associated with severity of provocation test-evoked symptoms in wheat-dependent exercise-induced anaphylaxis.
Allergology international : official journal of the Japanese Society of Allergology.
2019 Oct; 68(4):541-543. doi:
10.1016/j.alit.2019.04.007. [PMID: 31176598] - Shufang Yang, Lei Dai, Like Mao, Jinfang Liu, Fang Yuan, Zaigui Li, Yanxiang Gao. Effect of sodium tripolyphosphate incorporation on physical, structural, morphological and stability characteristics of zein and gliadin nanoparticles.
International journal of biological macromolecules.
2019 Sep; 136(?):653-660. doi:
10.1016/j.ijbiomac.2019.06.052. [PMID: 31195045] - Aurélie Jouanin, Jan G Schaart, Lesley A Boyd, James Cockram, Fiona J Leigh, Ruth Bates, Emma J Wallington, Richard G F Visser, Marinus J M Smulders. Outlook for coeliac disease patients: towards bread wheat with hypoimmunogenic gluten by gene editing of α- and γ-gliadin gene families.
BMC plant biology.
2019 Aug; 19(1):333. doi:
10.1186/s12870-019-1889-5. [PMID: 31370789] - Michael A Kutteh, May Abiad, Gary L Norman, William H Kutteh. Comparison of celiac disease markers in women with early recurrent pregnancy loss and normal controls.
American journal of reproductive immunology (New York, N.Y. : 1989).
2019 07; 82(1):e13127. doi:
10.1111/aji.13127. [PMID: 30977932] - Maurizio Mennini, Alessandro Fiocchi, Chiara M Trovato, Federica Ferrari, Donatella Iorfida, Salvatore Cucchiara, Monica Montuori. Anaphylaxis after wheat ingestion in a patient with coeliac disease: two kinds of reactions and the same culprit food.
European journal of gastroenterology & hepatology.
2019 Jul; 31(7):893-895. doi:
10.1097/meg.0000000000001421. [PMID: 30994495] - Ilaria Russo, Chiara Del Giorno, Ivana Giangrieco, Najla Hajji, Maria Antonietta Ciardiello, Paola Iovino, Carolina Ciacci. A Peptide from Kiwifruit Exerts Anti-Inflammatory Effects in Celiac Disease Mucosa.
Journal of the American College of Nutrition.
2019 07; 38(5):433-440. doi:
10.1080/07315724.2018.1541426. [PMID: 30794064] - Xing Chen, Yan Chen, Liqiang Zou, Xingcai Zhang, Yuqing Dong, Jizhou Tang, David Julian McClements, Wei Liu. Plant-Based Nanoparticles Prepared from Proteins and Phospholipids Consisting of a Core-Multilayer-Shell Structure: Fabrication, Stability, and Foamability.
Journal of agricultural and food chemistry.
2019 Jun; 67(23):6574-6584. doi:
10.1021/acs.jafc.9b02028. [PMID: 31117503] - Lamei Xue, Yan Li, Tingting Li, Haiou Pan, Jinxin Liu, Mingcong Fan, Haifeng Qian, Hui Zhang, Hao Ying, Li Wang. Phosphorylation and Enzymatic Hydrolysis with Alcalase and Papain Effectively Reduce Allergic Reactions to Gliadins in Normal Mice.
Journal of agricultural and food chemistry.
2019 Jun; 67(22):6313-6323. doi:
10.1021/acs.jafc.9b00569. [PMID: 31070910]