N-Methyl-a-aminoisobutyric acid (BioDeep_00000017934)
human metabolite Endogenous Chemicals and Drugs
代谢物信息卡片
2-Methyl-2-(methylazaniumyl)propanoate
化学式: C5H11NO2 (117.0789746)
中文名称: N,2-二甲基-丙氨酸
谱图信息:
最多检出来源 Bos taurus(endogenous) 88.89%
分子结构信息
SMILES: CC(C)(C(=O)O)NC
InChI: InChI=1S/C5H11NO2/c1-5(2,6-3)4(7)8/h6H,1-3H3,(H,7,8)
描述信息
N-Methyl-a-aminoisobutyric acid, also known as 2-(methylamino)isobutyrate or AMAIB, belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). N-Methyl-a-aminoisobutyric acid is a drug. N-Methyl-a-aminoisobutyric acid is a metabolite that is actively incorporated into the cell by the actions of Interleukin 1-beta and Interleukin 6 via sodium dependent transport systems (PMID 16202926).
N-Methyl-a-aminoisobutyric acid is a metabolite that is actively incorporated into the cell by the actions of Interleukin 1-beta and Interleukin 6 via sodium dependent transport systems (PMID 16202926) [HMDB]
同义名列表
22 个代谢物同义名
2-Methyl-2-(methylazaniumyl)propanoate; 2-methyl-2-(methylamino)propanoic acid; N-Methyl alpha-aminoisobutyric acid; N-Methyl-alpha-aminoisobutyric acid; N-Methyl-alpha-aminoisobutyrate; N-Methyl-a-aminoisobutyric acid; N-Methyl-α-aminoisobutyric acid; alpha-(methylamino)Isobutyrate; N-(methylamino)Isobutyric acid; a-(Methylamino)isobutyric acid; Α-(methylamino)isobutyric acid; 2-(Methylamino)isobutyric acid; alpha-Methylaminoisobutyrate; N-Methylaminoisobutyric acid; N-Methyl-α-aminoisobutyrate; N-Methyl-a-aminoisobutyrate; Α-(methylamino)isobutyrate; 2-(Methylamino)isobutyrate; a-(Methylamino)isobutyrate; N-Methylaminoisobutyrate; N,2-Dimethylalanine; AMAIB
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:192077
- ChEBI: CHEBI:134261
- PubChem: 6951124
- PubChem: 75725
- HMDB: HMDB0002141
- DrugBank: DB08832
- ChEMBL: CHEMBL1916079
- foodb: FDB022865
- chemspider: 68242
- CAS: 2566-34-9
- PMhub: MS000001266
- RefMet: N-Methyl-alpha-aminoisobutyric acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ana Paula Zanatta, Leila Zanatta, Renata Gonçalves, Ariane Zamoner, Fátima Regina Mena Barreto Silva. Integrin participates in the effect of thyroxine on plasma membrane in immature rat testis.
Biochimica et biophysica acta.
2013 Mar; 1830(3):2629-37. doi:
10.1016/j.bbagen.2012.10.022. [PMID: 23137442] - Masato Kobayashi, Fumiya Hashimoto, Kazuyo Ohe, Takahiro Nadamura, Kodai Nishi, Naoto Shikano, Ryuichi Nishii, Tatsuya Higashi, Hidehiko Okazawa, Keiichi Kawai. Transport mechanism of (11)C-labeled L- and D-methionine in human-derived tumor cells.
Nuclear medicine and biology.
2012 Nov; 39(8):1213-8. doi:
10.1016/j.nucmedbio.2012.06.006. [PMID: 22795787] - David T Thwaites, Catriona M H Anderson. The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.
British journal of pharmacology.
2011 Dec; 164(7):1802-16. doi:
10.1111/j.1476-5381.2011.01438.x. [PMID: 21501141] - Francesca Oppedisano, Cesare Indiveri. Reconstitution into liposomes of the B degrees -like glutamine-neutral amino acid transporter from renal cell plasma membrane.
Biochimica et biophysica acta.
2008 Oct; 1778(10):2258-65. doi:
10.1016/j.bbamem.2008.05.011. [PMID: 18572012] - Syuichi Nakajima, Naoto Shikano, Takashi Kotani, Masato Ogura, Ryuichi Nishii, Mitsuyoshi Yoshimoto, Naoto Yamaguchi, Yukio Iwamura, Nobuo Kubota, Nobuyoshi Ishikawa, Keiichi Kawai. Pharmacokinetics of 3-[125I]iodo-alpha-methyl-L-tyrosine, a tumor imaging agent, after probenecid loading in mice implanted with colon cancer DLD-1 cells.
Nuclear medicine and biology.
2007 Nov; 34(8):1003-8. doi:
10.1016/j.nucmedbio.2007.06.017. [PMID: 17998105] - Zhou Zhang, Christof Grewer. The sodium-coupled neutral amino acid transporter SNAT2 mediates an anion leak conductance that is differentially inhibited by transported substrates.
Biophysical journal.
2007 Apr; 92(7):2621-32. doi:
10.1529/biophysj.106.100776. [PMID: 17237199] - Takahiro Hatanaka, Yasue Hatanaka, Jun-Ichi Tsuchida, Vadivel Ganapathy, Mitsutoshi Setou. Amino acid transporter ATA2 is stored at the trans-Golgi network and released by insulin stimulus in adipocytes.
The Journal of biological chemistry.
2006 Dec; 281(51):39273-84. doi:
10.1074/jbc.m604534200. [PMID: 17050538] - Takahiro Hatanaka, Yasue Hatanaka, Mitsutoshi Setou. Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2.
The Journal of biological chemistry.
2006 Nov; 281(47):35922-30. doi:
10.1074/jbc.m606577200. [PMID: 17003038] - Nikolaos Dimopoulos, Maria Watson, Kei Sakamoto, Harinder S Hundal. Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells.
The Biochemical journal.
2006 Nov; 399(3):473-81. doi:
10.1042/bj20060244. [PMID: 16822230] - Helen N Jones, Cheryl J Ashworth, Ken R Page, Harry J McArdle. Cortisol stimulates system A amino acid transport and SNAT2 expression in a human placental cell line (BeWo).
American journal of physiology. Endocrinology and metabolism.
2006 Sep; 291(3):E596-603. doi:
10.1152/ajpendo.00359.2005. [PMID: 16621896] - Seiji Miyauchi, Emily L Abbot, Lina Zhuang, Radhika Subramanian, Vadivel Ganapathy, David T Thwaites. Isolation and function of the amino acid transporter PAT1 (slc36a1) from rabbit and discrimination between transport via PAT1 and system IMINO in renal brush-border membrane vesicles.
Molecular membrane biology.
2005 Nov; 22(6):549-59. doi:
10.1080/09687860500421779. [PMID: 16373326] - Boonrit Thongsong, Radhika K Subramanian, Vadivel Ganapathy, Puttur D Prasad. Inhibition of amino acid transport system a by interleukin-1beta in trophoblasts.
Journal of the Society for Gynecologic Investigation.
2005 Oct; 12(7):495-503. doi:
10.1016/j.jsgi.2005.06.008. [PMID: 16202926] - Sumin Gu, Carla J Villegas, Jean X Jiang. Differential regulation of amino acid transporter SNAT3 by insulin in hepatocytes.
The Journal of biological chemistry.
2005 Jul; 280(28):26055-62. doi:
10.1074/jbc.m504401200. [PMID: 15899884] - Kazunari Tanaka, Akira Yamamoto, Takuya Fujita. Functional expression and adaptive regulation of Na+ -dependent neutral amino acid transporter SNAT2/ATA2 in normal human astrocytes under amino acid starved condition.
Neuroscience letters.
2005 Apr; 378(2):70-5. doi:
10.1016/j.neulet.2004.12.030. [PMID: 15774260] - Tom Schilling, Claudia Eder. A novel physiological mechanism of glycine-induced immunomodulation: Na+-coupled amino acid transporter currents in cultured brain macrophages.
The Journal of physiology.
2004 Aug; 559(Pt 1):35-40. doi:
10.1113/jphysiol.2004.070763. [PMID: 15243140] - E Cummings, H S Hundal, H Wackerhage, M Hope, M Belle, E Adeghate, J Singh. Momordica charantia fruit juice stimulates glucose and amino acid uptakes in L6 myotubes.
Molecular and cellular biochemistry.
2004 Jun; 261(1-2):99-104. doi:
10.1023/b:mcbi.0000028743.75669.ab. [PMID: 15362491] - Naoto Shikano, Keiichi Kawai, Syuichi Nakajima, Akiko Kubodera, Nobuo Kubota, Nobuyoshi Ishikawa, Hideo Saji. Transcellular transport of radioiodinated 3-iodo-alpha-methyl-L-tyrosine across monolayers of kidney epithelial cell line LLC-PK1.
Annals of nuclear medicine.
2004 May; 18(3):227-34. doi:
10.1007/bf02985004. [PMID: 15233284] - Zhong Chen, David J Kennedy, Katherine A Wake, Lina Zhuang, Vadivel Ganapathy, David T Thwaites. Structure, tissue expression pattern, and function of the amino acid transporter rat PAT2.
Biochemical and biophysical research communications.
2003 May; 304(4):747-54. doi:
10.1016/s0006-291x(03)00648-x. [PMID: 12727219] - Do Kyung Kim, Yoshikatsu Kanai, Hirotaka Matsuo, Ju Young Kim, Arthit Chairoungdua, Yukari Kobayashi, Atsushi Enomoto, Seok Ho Cha, Tomoyuki Goya, Hitoshi Endou. The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Genomics.
2002 Jan; 79(1):95-103. doi:
10.1006/geno.2001.6678. [PMID: 11827462] - Stuart Cramer, Mark Beveridge, Michael Kilberg, Donald Novak. Physiological importance of system A-mediated amino acid transport to rat fetal development.
American journal of physiology. Cell physiology.
2002 Jan; 282(1):C153-60. doi:
10.1152/ajpcell.2002.282.1.c153. [PMID: 11742808] - T Nakanishi, R Kekuda, Y J Fei, T Hatanaka, M Sugawara, R G Martindale, F H Leibach, P D Prasad, V Ganapathy. Cloning and functional characterization of a new subtype of the amino acid transport system N.
American journal of physiology. Cell physiology.
2001 Dec; 281(6):C1757-68. doi:
10.1152/ajpcell.2001.281.6.c1757. [PMID: 11698233] - D Novak, F Quiggle, C Artime, M Beveridge. Regulation of glutamate transport and transport proteins in a placental cell line.
American journal of physiology. Cell physiology.
2001 Sep; 281(3):C1014-22. doi:
10.1152/ajpcell.2001.281.3.c1014. [PMID: 11502579] - H Varoqui, H Zhu, D Yao, H Ming, J D Erickson. Cloning and functional identification of a neuronal glutamine transporter.
The Journal of biological chemistry.
2000 Feb; 275(6):4049-54. doi:
10.1074/jbc.275.6.4049. [PMID: 10660562] - A Yee, B Szymczyna, J D O'Neil. Backbone dynamics of detergent-solubilized alamethicin from amide hydrogen exchange measurements.
Biochemistry.
1999 May; 38(20):6489-98. doi:
10.1021/bi982959t. [PMID: 10350467] - U Warskulat, M Wettstein, D Häussinger. Betaine is an osmolyte in RAW 264.7 mouse macrophages.
FEBS letters.
1995 Dec; 377(1):47-50. doi:
10.1016/0014-5793(95)01317-2. [PMID: 8543016] - N J Espat, B P Bode, D S Lind, E M Copeland, W W Souba. Normalization of tumor-induced increases in hepatic amino acid transport after surgical resection.
Annals of surgery.
1995 Jan; 221(1):50-8. doi:
10.1097/00000658-199501000-00006. [PMID: 7826161] - D Mahendran, S Byrne, P Donnai, S W D'Souza, J D Glazier, C J Jones, C P Sibley. Na+ transport, H+ concentration gradient dissipation, and system A amino acid transporter activity in purified microvillous plasma membrane isolated from first-trimester human placenta: comparison with the term microvillous membrane.
American journal of obstetrics and gynecology.
1994 Dec; 171(6):1534-40. doi:
10.1016/0002-9378(94)90397-2. [PMID: 7802063] - B Mackenzie, M Panayotova-Heiermann, D D Loo, J E Lever, E M Wright. SAAT1 is a low affinity Na+/glucose cotransporter and not an amino acid transporter. A reinterpretation.
The Journal of biological chemistry.
1994 Sep; 269(36):22488-91. doi:
NULL. [PMID: 8077195] - Y Inoue, B P Bode, W W Souba. Antibody to tumor necrosis factor attenuates endotoxin-stimulated amino acid transport in rat liver.
Surgery.
1994 Aug; 116(2):356-65; discussion 365. doi:
NULL. [PMID: 8048001] - N J Espat, E M Copeland, W W Souba. Accelerated hepatic arginine transport in the tumor-bearing rat.
Annals of surgical oncology.
1994 Mar; 1(2):147-56. doi:
10.1007/bf02303559. [PMID: 7834440] - N J Espat, E M Copeland, W W Souba. Harry M. Vars Research Award. Influence of fasting on glutamine transport in rat liver.
JPEN. Journal of parenteral and enteral nutrition.
1993 Nov; 17(6):493-500. doi:
10.1177/0148607193017006493. [PMID: 8301800] - A J Pacitti, Y Inoue, W W Souba. Tumor necrosis factor stimulates amino acid transport in plasma membrane vesicles from rat liver.
The Journal of clinical investigation.
1993 Feb; 91(2):474-83. doi:
10.1172/jci116225. [PMID: 8432856] - A R Tovar, J K Tews, N Torres, D C Madsen, A E Harper. Competition for transport of amino acids into rat heart: effect of competitors on protein synthesis and degradation.
Metabolism: clinical and experimental.
1992 Sep; 41(9):925-33. doi:
10.1016/0026-0495(92)90116-r. [PMID: 1518421] - H S Hundal, T Ramlal, R Reyes, L A Leiter, A Klip. Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells.
Endocrinology.
1992 Sep; 131(3):1165-73. doi:
10.1210/endo.131.3.1505458. [PMID: 1505458] - A Felipe, C Soler, J D McGivan. Amino acid deprivation leads to the emergence of System A activity and the synthesis of a specific membrane glycoprotein in the bovine renal epithelial cell line NBL-1.
The Biochemical journal.
1992 Jun; 284 ( Pt 2)(?):577-82. doi:
10.1042/bj2840577. [PMID: 1599439] - A Gumà, A Castelló, X Testar, M Palacín, A Zorzano. Differential sensitivity of insulin- and adaptive-regulation-induced system A activation to microtubular function in skeletal muscle.
The Biochemical journal.
1992 Jan; 281 ( Pt 2)(?):407-11. doi:
10.1042/bj2810407. [PMID: 1736891] - P Luque, J Márquez, I Núñez de Castro, M A Medina. L-alanine transport by systems A and ASC in plasma membrane vesicles isolated from Ehrlich cells.
Biochemistry international.
1991 Dec; 25(5):913-8. doi:
. [PMID: 1804109] - A R Tovar, J K Tews, N Torres, A E Harper. Neutral amino acid transport into rat skeletal muscle: competition, adaptive regulation, and effects of insulin.
Metabolism: clinical and experimental.
1991 Apr; 40(4):410-9. doi:
10.1016/0026-0495(91)90153-n. [PMID: 2011083] - E A Gulve, G D Cartee, J H Youn, J O Holloszy. Prolonged incubation of skeletal muscle increases system A amino acid transport.
The American journal of physiology.
1991 Jan; 260(1 Pt 1):C88-95. doi:
10.1152/ajpcell.1991.260.1.c88. [PMID: 1987782] - E Pola, J Bertran, A Roca, M Palacín, A Zorzano, X Testar. Sensitivity of system A and ASC transport activities to thiol-group-modifying reagents in rat liver plasma-membrane vesicles. Evidence for a direct binding of N-ethylmaleimide and iodoacetamide on A and ASC carriers.
The Biochemical journal.
1990 Oct; 271(2):297-303. doi:
10.1042/bj2710297. [PMID: 2241916] - M E Mailliard, M S Kilberg. Sodium-dependent neutral amino acid transport by human liver plasma membrane vesicles.
The Journal of biological chemistry.
1990 Aug; 265(24):14321-6. doi:
NULL. [PMID: 2387853] - G Bourdel, M Forestier, B Gouhot. Na(+)-dependent transport of alanine and serine by liver plasma-membrane vesicles from rats fed a low-protein or a high-protein diet.
Biochimica et biophysica acta.
1990 Jul; 1026(1):1-12. doi:
10.1016/0005-2736(90)90325-i. [PMID: 2165806] - S S Blumenthal, D L Lewand, M A Buday, J G Kleinman, S K Krezoski, D H Petering. Cadmium inhibits glucose uptake in primary cultures of mouse cortical tubule cells.
The American journal of physiology.
1990 Jun; 258(6 Pt 2):F1625-33. doi:
10.1152/ajprenal.1990.258.6.f1625. [PMID: 2360656] - B J Maroni, R W Haesemeyer, M H Kutner, W E Mitch. Kinetics of system A amino acid uptake by muscle: effects of insulin and acute uremia.
The American journal of physiology.
1990 May; 258(5 Pt 2):F1304-10. doi:
10.1152/ajprenal.1990.258.5.f1304. [PMID: 2186634] - J H James, P O Hasselgren, R P Hummel, B W Warner, J E Fischer. Effect of sepsis on amino acid transport system A and its response to insulin in incubated rat skeletal muscle.
Metabolism: clinical and experimental.
1990 Apr; 39(4):335-40. doi:
10.1016/0026-0495(90)90245-8. [PMID: 2182970] - A D Fong, M E Handlogten, M S Kilberg. Substrate-dependent adaptive regulation and trans-inhibition of System A-mediated amino acid transport. Studies using rat hepatoma plasma membrane vesicles.
Biochimica et biophysica acta.
1990 Mar; 1022(3):325-32. doi:
10.1016/0005-2736(90)90281-r. [PMID: 1690572] - C Aussel, S Rousseau-Loric, L Cynober, J Agneray, O G Ekindjian. Neutral amino acid transport in human synovial cells: substrate specificity of adaptative regulation and transinhibition.
Journal of cellular physiology.
1989 Oct; 141(1):103-10. doi:
10.1002/jcp.1041410116. [PMID: 2777895] - S D Hoeltzli, C H Smith. Alanine transport systems in isolated basal plasma membrane of human placenta.
The American journal of physiology.
1989 Mar; 256(3 Pt 1):C630-7. doi:
10.1152/ajpcell.1989.256.3.c630. [PMID: 2923196] - D J Topliss, E Kolliniatis, J W Barlow, C F Lim, J R Stockigt. Uptake of 3,5,3'-triiodothyronine by cultured rat hepatoma cells is inhibitable by nonbile acid cholephils, diphenylhydantoin, and nonsteroidal antiinflammatory drugs.
Endocrinology.
1989 Feb; 124(2):980-6. doi:
10.1210/endo-124-2-980. [PMID: 2912709] - C Hofmann, M F White, J Whittaker. Human insulin receptors expressed in insulin-insensitive mouse fibroblasts couple with extant cellular effector systems to confer insulin sensitivity and responsiveness.
Endocrinology.
1989 Jan; 124(1):257-64. doi:
10.1210/endo-124-1-257. [PMID: 2462489] - J I McCormick, R M Johnstone. Simple and effective purification of a Na+-dependent amino acid transport system from Ehrlich ascites cell plasma membrane.
Proceedings of the National Academy of Sciences of the United States of America.
1988 Nov; 85(21):7877-81. doi:
10.1073/pnas.85.21.7877. [PMID: 2847146] - A R Quesada, J D McGivan. A rapid method for the functional reconstitution of amino acid transport systems from rat liver plasma membranes. Partial purification of System A.
The Biochemical journal.
1988 Nov; 255(3):963-9. doi:
10.1042/bj2550963. [PMID: 3214433] - A Tovar, J K Tews, N Torres, A E Harper. Some characteristics of threonine transport across the blood-brain barrier of the rat.
Journal of neurochemistry.
1988 Oct; 51(4):1285-93. doi:
10.1111/j.1471-4159.1988.tb03098.x. [PMID: 3138388] - F Ciardiello, B Sanfilippo, K Yanagihara, N Kim, G Tortora, R H Bassin, W R Kidwell, D S Salomon. Differential growth sensitivity to 4-cis-hydroxy-L-proline of transformed rodent cell lines.
Cancer research.
1988 May; 48(9):2483-91. doi:
. [PMID: 2833347] - W D Dawson, J S Cook. Biphasic response of Na+-dependent amino acid transport to tumor promoting phorbol esters in cultured renal epithelial cells, LLC-PK1.
Progress in clinical and biological research.
1988; 258(?):121-33. doi:
NULL. [PMID: 3380819] - L Panasci, A McQuillan, W Feindel. The cytolytic effect of L-2,4 diaminobutyric acid with malignant glioma cells and fibroblasts.
Cancer chemotherapy and pharmacology.
1988; 21(2):143-4. doi:
10.1007/bf00257361. [PMID: 3349563] - Y Kudo, K Yamada, A Fujiwara, T Kawasaki. Characterization of amino acid transport systems in human placental brush-border membrane vesicles.
Biochimica et biophysica acta.
1987 Nov; 904(2):309-18. doi:
10.1016/0005-2736(87)90380-4. [PMID: 3663675] - W D Dawson, J S Cook. Parallel changes in amino acid transport and protein kinase C localization in LLC-PK1 cells treated with TPA or diradylglycerols.
Journal of cellular physiology.
1987 Jul; 132(1):104-10. doi:
10.1002/jcp.1041320114. [PMID: 3597547] - M Pastor-Anglada, X Remesar, G Bourdel. Alanine uptake by liver at midpregnancy in rats.
The American journal of physiology.
1987 Mar; 252(3 Pt 1):E408-13. doi:
10.1152/ajpendo.1987.252.3.e408. [PMID: 3826365] - R Zibirre, P Poronnik, G Koch. Na+-dependent amino acid transport is a major factor determining the rate of (Na+,K+)-ATPase mediated cation transport in intact HeLa cells.
Journal of cellular physiology.
1986 Oct; 129(1):85-93. doi:
10.1002/jcp.1041290113. [PMID: 3020065] - B J Maroni, G Karapanos, W E Mitch. System A amino acid transport in incubated muscle: effects of insulin and acute uremia.
The American journal of physiology.
1986 Jul; 251(1 Pt 2):F74-80. doi:
10.1152/ajprenal.1986.251.1.f74. [PMID: 3524266] - B J Maroni, G Karapanos, W E Mitch. System ASC and sodium-independent neutral amino acid transport in muscle of uremic rats.
The American journal of physiology.
1986 Jul; 251(1 Pt 2):F81-6. doi:
10.1152/ajprenal.1986.251.1.f81. [PMID: 3524267] - M A Schenerman, M S Kilberg. Maintenance of glucagon-stimulated system A amino acid transport activity in rat liver plasma membrane vesicles.
Biochimica et biophysica acta.
1986 Apr; 856(3):428-36. doi:
10.1016/0005-2736(86)90133-1. [PMID: 3964688] - O Bussolati, P C Laris, N Longo, V Dall'Asta, R Franchi-Gazzola, G G Guidotti, G C Gazzola. Effect of extracellular potassium on amino acid transport and membrane potential in fetal human fibroblasts.
Biochimica et biophysica acta.
1986 Jan; 854(2):240-50. doi:
10.1016/0005-2736(86)90116-1. [PMID: 3942729] - S E Brown, K J Kim, B E Goodman, J R Wells, E D Crandall. Sodium-amino acid cotransport by type II alveolar epithelial cells.
Journal of applied physiology (Bethesda, Md. : 1985).
1985 Nov; 59(5):1616-22. doi:
10.1152/jappl.1985.59.5.1616. [PMID: 4066594] - P Boerner, E Racker. Methionine-sensitive glycolysis in transformed cells.
Proceedings of the National Academy of Sciences of the United States of America.
1985 Oct; 82(20):6750-4. doi:
10.1073/pnas.82.20.6750. [PMID: 2995983] - J E Lever, B G Kennedy, R Vasan. Amino acid transport in kidney epithelial cell line (MDCK): characteristics of Na+/amino acid symport in membrane vesicles and basolateral localization in cell monolayers.
Archives of biochemistry and biophysics.
1984 Nov; 234(2):330-40. doi:
10.1016/0003-9861(84)90278-9. [PMID: 6093696] - H J Ross, E M Wright. Neutral amino acid transport by plasma membrane vesicles of the rabbit choroid plexus.
Brain research.
1984 Mar; 295(1):155-60. doi:
10.1016/0006-8993(84)90826-6. [PMID: 6713173] - C Grunfeld, D S Jones. Insulin-stimulated methylaminoisobutyric acid uptake in 3T3-L1 fibroblasts and fat cells.
Endocrinology.
1983 Nov; 113(5):1763-70. doi:
10.1210/endo-113-5-1763. [PMID: 6354697] - M F White, H N Christensen. Simultaneous regulation of amino acid influx and efflux by system A in the hepatoma cell HTC. Ouabain simulates the starvation-induced derepression of system A amino acid transport.
The Journal of biological chemistry.
1983 Jul; 258(13):8028-38. doi:
NULL. [PMID: 6863276] - K Amsler, C Shaffer, J S Cook. Growth-dependent AIB and meAIB uptake in LLC-PK1 cells: effects of differentiation inducers and of TPA.
Journal of cellular physiology.
1983 Feb; 114(2):184-90. doi:
10.1002/jcp.1041140207. [PMID: 6185510] - R Franchi-Gazzola, G C Gazzola, V Dall'Asta, G G Guidotti. The transport of alanine, serine, and cysteine in cultured human fibroblasts.
The Journal of biological chemistry.
1982 Aug; 257(16):9582-7. doi:
NULL. [PMID: 6809740] - M S Kilberg. Amino acid transport in isolated rat hepatocytes.
The Journal of membrane biology.
1982; 69(1):1-12. doi:
10.1007/bf01871236. [PMID: 6811749] - M Gulumian, K L Manchester. Influence of serum and amino acids on the accumulation of aminoisobutyrate by rat hepatoma cells. A dedifferentiation of transport routes?.
Biochimica et biophysica acta.
1981 Nov; 649(1):24-30. doi:
10.1016/0005-2736(81)90004-3. [PMID: 7306545] - M Ohsawa, M S Kilberg, G Kimmel, H N Christensen. Energization of amino acid transport in energy-depleted Ehrlich cells and plasma membrane vesicles.
Biochimica et biophysica acta.
1980 Jun; 599(1):175-90. doi:
10.1016/0005-2736(80)90066-8. [PMID: 7397146]