1,2-Diphenyl-3,5-dioxo-4-(3-hydroxybutyl)pyrazolidine (BioDeep_00000179328)

   

human metabolite blood metabolite


代谢物信息卡片


4-(3-hydroxybutyl)-1,2-diphenylpyrazolidine-3,5-dione

化学式: C19H20N2O3 (324.147385)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)O
InChI: InChI=1S/C19H20N2O3/c1-14(22)12-13-17-18(23)20(15-8-4-2-5-9-15)21(19(17)24)16-10-6-3-7-11-16/h2-11,14,17,22H,12-13H2,1H3

描述信息

同义名列表

4 个代谢物同义名

4-(3-hydroxybutyl)-1,2-diphenylpyrazolidine-3,5-dione; 1,2-Diphenyl-3,5-dioxo-4-(3-hydroxybutyl)pyrazolidine; (+-)-Isomer OF gamma-hydroxyphenylbutazone; gamma-Hydroxyphenylbutazone



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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Plant Reactome(0)

INOH(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • P C Mills, J C Ng, K V Skelton, A A Seawright, D E Auer. Phenylbutazone in racing greyhounds: plasma and urinary residues 24 and 48 hours after a single intravenous administration. Australian veterinary journal. 1995 Aug; 72(8):304-8. doi: 10.1111/j.1751-0813.1995.tb03560.x. [PMID: 8579562]
  • J Landuyt, F T Delbeke, M Debackere. The intramuscular bioavailability of a phenylbutazone preparation in the horse. Journal of veterinary pharmacology and therapeutics. 1993 Dec; 16(4):494-500. doi: 10.1111/j.1365-2885.1993.tb00216.x. [PMID: 8126767]
  • P Lees, T Ayliffe, T E Maitho, J B Taylor. Pharmacokinetics, metabolism and excretion of phenylbutazone in cattle following intravenous, intramuscular and oral administration. Research in veterinary science. 1988 Jan; 44(1):57-67. doi: 10.1016/0034-5288(88)90014-8. [PMID: 3375589]
  • P Lees, J B Taylor, T E Maitho, J D Millar, A J Higgins. Metabolism, excretion, pharmacokinetics and tissue residues of phenylbutazone in the horse. The Cornell veterinarian. 1987 Apr; 77(2):192-211. doi: . [PMID: 3568689]
  • M J Franssen, Y Tan, I Freij, C A Van Ginneken, F W Gribnau. Specimen handling in an HPLC determination of phenylbutazone and its major metabolites in plasma, avoiding degradation of the compounds. Pharmaceutisch weekblad. Scientific edition. 1986 Aug; 8(4):229-33. doi: 10.1007/bf01957783. [PMID: 3763367]
  • R Gronwall, G Price. Estimation of urine flow rate in mares. American journal of veterinary research. 1985 May; 46(5):1107-10. doi: NULL. [PMID: 4003886]
  • P Lees, T E Maitho, J B Taylor. Pharmacokinetics of phenylbutazone in two age groups of ponies: a preliminary study. The Veterinary record. 1985 Mar; 116(9):229-32. doi: 10.1136/vr.116.9.229. [PMID: 4002593]
  • E L Gerring, P Lees, J B Taylor. Pharmacokinetics of phenylbutazone and its metabolites in the horse. Equine veterinary journal. 1981 Jul; 13(3):152-7. doi: 10.1111/j.2042-3306.1981.tb03472.x. [PMID: 7297544]
  • T Marunaka, T Shibata, Y Minami, Y Umeno. Simultaneous determination of phenylbutazone and its metabolites in plasma and urine by high-performance liquid chromatography. Journal of chromatography. 1980 Sep; 183(3):331-8. doi: 10.1016/s0378-4347(00)81713-2. [PMID: 7419650]
  • M Sano. Subcellular localizations of guanylate cyclase and 3',5'-cyclic nucleotide phosphodiesterase in sea urchin sperm. Biochimica et biophysica acta. 1976 Apr; 428(2):525-31. doi: 10.1016/0304-4165(76)90061-1. [PMID: 6049]
  • K K Midha, I J McGilveray, C Charette. GLC determination of gamma-hydroxyphenylbutazone in plasma. Journal of pharmaceutical sciences. 1974 Nov; 63(11):1751-4. doi: 10.1002/jps.2600631118. [PMID: 4427237]