Formamidine (BioDeep_00000179185)

   

human metabolite blood metabolite


Metabolite Card


Formamidine hydrochloride

  Formula: CH4N2 (44.0374)
Chinese Names:
  Spectrum Hits: Top Source () %

Molecular Structure

SMILES: C(=N)N
InChI: InChI=1S/CH4N2/c2-1-3/h1H,(H3,2,3)



Cross Reference

6 cross reference id

Classification Terms

Related Pathways

Reactome()

BioCyc()

PlantCyc()

Biological Process

related biological process reactions.

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

1 organism taxonomy source information

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

Sub-cellular location Genes


Literature Reference

  • Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. Hazardous effects of octopamine receptor agonists on altering metabolism-related genes and behavior of Drosophila melanogaster. Chemosphere. 2020 Aug; 253(?):126629. doi: 10.1016/j.chemosphere.2020.126629. [PMID: 32283422]
  • Mark Enstrom, Kiara Held, Beth Ramage, Mitchell Brittnacher, Larry Gallagher, Colin Manoil. Genotype-phenotype associations in a nonmodel prokaryote. mBio. 2012; 3(2):. doi: 10.1128/mbio.00001-12. [PMID: 22434848]
  • John T Brosnan, Robin P da Silva, Margaret E Brosnan. The metabolic burden of creatine synthesis. Amino acids. 2011 May; 40(5):1325-31. doi: 10.1007/s00726-011-0853-y. [PMID: 21387089]
  • Xianhuo Wang, Xingmei Duan, Guangli Yang, Xiaoyan Zhang, Linyu Deng, Hao Zheng, Chongyang Deng, Jiaolin Wen, Ning Wang, Cheng Peng, Xia Zhao, Yuquan Wei, Lijuan Chen. Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral gliosarcoma model and human U251 xenograft glioma model. PloS one. 2011 Apr; 6(4):e18490. doi: 10.1371/journal.pone.0018490. [PMID: 21559510]
  • Dipak Panigrahy, Arja Kaipainen, Emily R Greene, Sui Huang. Cytochrome P450-derived eicosanoids: the neglected pathway in cancer. Cancer metastasis reviews. 2010 Dec; 29(4):723-35. doi: 10.1007/s10555-010-9264-x. [PMID: 20941528]
  • Chen-Ping Chou, Shui-Yuan Lu, Tzuu-Huei Ueng. Modulation of serum concentrations and hepatic metabolism of 17beta-estradiol and testosterone by amitraz in rats. Archives of toxicology. 2008 Oct; 82(10):729-37. doi: 10.1007/s00204-008-0288-8. [PMID: 18301880]
  • L Institoris, H Banfi, Zs Lengyel, A Papp, L Nagymajtenyi. A study on immunotoxicological effects of subacute amitraz exposure in rats. Human & experimental toxicology. 2007 May; 26(5):441-5. doi: 10.1177/0960327107076887. [PMID: 17623769]
  • P A Oglesby, K E Joubert, T Meiring. Canine renal cortical necrosis and haemorrhage following ingestion of an Amitraz-formulated insecticide dip. Journal of the South African Veterinary Association. 2006 Sep; 77(3):160-3. doi: 10.4102/jsava.v77i3.366. [PMID: 17137059]
  • Jian-Xin Guo, Stewart J Wood, Sunil A David, Gerald H Lushington. Molecular modeling analysis of the interaction of novel bis-cationic ligands with the lipid A moiety of lipopolysaccharide. Bioorganic & medicinal chemistry letters. 2006 Feb; 16(3):714-7. doi: 10.1016/j.bmcl.2005.10.025. [PMID: 16266804]
  • Hüseyin Caksen, Dursun Odabaş, Sükrü Arslan, Cihangir Akgün, Bülent Ataş, Sinan Akbayram, Oğuz Tuncer. Report of eight children with amitraz intoxication. Human & experimental toxicology. 2003 Feb; 22(2):95-7. doi: 10.1191/0960327103ht333sr. [PMID: 12693834]
  • Jörg Hauptmann, Torsten Steinmetzer, Helmut Vieweg, Peter Wikström, Jürg Stürzebecher. Influence of structural variations in peptidomimetic 4-amidinophenylalanine-derived thrombin inhibitors on plasma clearance and biliary excretion in rats. Pharmaceutical research. 2002 Jul; 19(7):1027-33. doi: 10.1023/a:1016426724831. [PMID: 12180535]
  • T Goto, H Sakashita, K Murakami, M Sugiura, T Kondo, C Fukaya. Novel histamine H3 receptor antagonists: synthesis and evaluation of formamidine and S-methylisothiourea derivatives. Chemical & pharmaceutical bulletin. 1997 Feb; 45(2):305-11. doi: 10.1248/cpb.45.305. [PMID: 9118445]
  • S A Seoh, D Busath. Gramicidin tryptophans mediate formamidinium-induced channel stabilization. Biophysical journal. 1995 Jun; 68(6):2271-9. doi: 10.1016/s0006-3495(95)80409-1. [PMID: 7544164]
  • S A Seoh, D D Busath. Formamidinium-induced dimer stabilization and flicker block behavior in homo- and heterodimer channels formed by gramicidin A and N-acetyl gramicidin A. Biophysical journal. 1993 Nov; 65(5):1817-27. doi: 10.1016/s0006-3495(93)81239-6. [PMID: 7507714]
  • S A Seoh, D Busath. The permeation properties of small organic cations in gramicidin A channels. Biophysical journal. 1993 Apr; 64(4):1017-28. doi: 10.1016/s0006-3495(93)81467-x. [PMID: 7684267]
  • J B WALKER. Formamidine group transfer in extracts of human pancreas, liver, and kidney. Biochimica et biophysica acta. 1963 Jun; 73(?):241-7. doi: 10.1016/0006-3002(63)90308-1. [PMID: 13998495]


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