Flavan (BioDeep_00000179073)

   

human metabolite blood metabolite


代谢物信息卡片


3,4-Dihydro-2-phenyl-2H-1-benzopyran

化学式: C15H14O (210.1044594)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC2=CC=CC=C2OC1C1=CC=CC=C1
InChI: InChI=1S/C15H14O/c1-2-6-12(7-3-1)15-11-10-13-8-4-5-9-14(13)16-15/h1-9,15H,10-11H2

描述信息

同义名列表

3 个代谢物同义名

3,4-Dihydro-2-phenyl-2H-1-benzopyran; 2-phenyl-3,4-dihydro-2H-1-benzopyran; Flavan



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jana Thill, Ionela Regos, Mohamed A Farag, Asma F Ahmad, Justyna Kusek, Ana Castro, Karin Schlangen, Christine Hayot Carbonero, Ilya Z Gadjev, Lydia M J Smith, Heidi Halbwirth, Dieter Treutter, Karl Stich. Polyphenol metabolism provides a screening tool for beneficial effects of Onobrychis viciifolia (sainfoin). Phytochemistry. 2012 Oct; 82(?):67-80. doi: 10.1016/j.phytochem.2012.05.030. [PMID: 22818525]
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  • Stanisław Weidner, Anna Powałka, Magdalena Karamać, Ryszard Amarowicz. Extracts of phenolic compounds from seeds of three wild grapevines-comparison of their antioxidant activities and the content of phenolic compounds. International journal of molecular sciences. 2012; 13(3):3444-3457. doi: 10.3390/ijms13033444. [PMID: 22489161]
  • Neyres Zinia Taveira De Jesus, Heloina de Souza Falcão, Isis Fernandes Gomes, Thiago Jose de Almeida Leite, Gedson Rodrigues de Morais Lima, Jose Maria Barbosa-Filho, Josean Fechine Tavares, Marcelo Sobral da Silva, Petrônio Filgueiras de Athayde-Filho, Leonia Maria Batista. Tannins, peptic ulcers and related mechanisms. International journal of molecular sciences. 2012; 13(3):3203-3228. doi: 10.3390/ijms13033203. [PMID: 22489149]
  • Li-Yin Chen, Ih-Sheng Chen, Chien-Fang Peng. Structural elucidation and bioactivity of biflavonoids from the stems of Wikstroemia taiwanensis. International journal of molecular sciences. 2012; 13(1):1029-1038. doi: 10.3390/ijms13011029. [PMID: 22312302]
  • Shu-fen Xu, Bo Zou, Jie Yang, Ping Yao, Chun-mei Li. Characterization of a highly polymeric proanthocyanidin fraction from persimmon pulp with strong Chinese cobra PLA2 inhibition effects. Fitoterapia. 2012 Jan; 83(1):153-60. doi: 10.1016/j.fitote.2011.10.005. [PMID: 22037569]
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  • Jian Zhao, David Huhman, Gail Shadle, Xian-Zhi He, Lloyd W Sumner, Yuhong Tang, Richard A Dixon. MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula. The Plant cell. 2011 Apr; 23(4):1536-55. doi: 10.1105/tpc.110.080804. [PMID: 21467581]
  • Cheng-Ying Shi, Hua Yang, Chao-Ling Wei, Oliver Yu, Zheng-Zhu Zhang, Chang-Jun Jiang, Jun Sun, Ye-Yun Li, Qi Chen, Tao Xia, Xiao-Chun Wan. Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds. BMC genomics. 2011 Feb; 12(?):131. doi: 10.1186/1471-2164-12-131. [PMID: 21356090]
  • Aneta Janecki, Andreas Conrad, Inge Engels, Uwe Frank, Herbert Kolodziej. Evaluation of an aqueous-ethanolic extract from Pelargonium sidoides (EPs® 7630) for its activity against group A-streptococci adhesion to human HEp-2 epithelial cells. Journal of ethnopharmacology. 2011 Jan; 133(1):147-52. doi: 10.1016/j.jep.2010.09.018. [PMID: 20883767]
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  • Ayako Kumagai, Nanao Horike, Yudai Satoh, Tatsuya Uebi, Tsutomu Sasaki, Yumi Itoh, Yoshiyuki Hirata, Kozue Uchio-Yamada, Kazuo Kitagawa, Shinichi Uesato, Hidehisa Kawahara, Hiroshi Takemori, Yasuo Nagaoka. A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells. PloS one. 2011; 6(10):e26148. doi: 10.1371/journal.pone.0026148. [PMID: 22022544]
  • Yan-Bing Wu, Yueh-Hsiung Kuo, Ming-An Ouyang. Novel 4-(2-methylphenyl)-flavan, rhusjavanins A and B, from the roots of Rhus semialata. Natural product research. 2010 Oct; 24(17):1643-7. doi: 10.1080/14786419.2010.483528. [PMID: 20954092]
  • Wei-Li Han, Xiao-Qi Zhang, Guo-Cai Wang, Ying Wang, Wen-Cai Ye. Three new flavane glucosides from the leaves of Morus wittiorum. Journal of Asian natural products research. 2010 Aug; 12(8):680-4. doi: 10.1080/10286020.2010.490780. [PMID: 20706904]
  • Yukihiro Asami, Ryo Horie, Hiroshi Hamamoto, Kazuhisa Sekimizu. Use of silkworms for identification of drug candidates having appropriate pharmacokinetics from plant sources. BMC pharmacology. 2010 Jun; 10(?):7. doi: 10.1186/1471-2210-10-7. [PMID: 20537191]
  • Dieter Treutter. Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. International journal of molecular sciences. 2010 Mar; 11(3):807-57. doi: 10.3390/ijms11030807. [PMID: 20479987]
  • Xiaoyun Meng, Larissa A Munishkina, Anthony L Fink, Vladimir N Uversky. Effects of Various Flavonoids on the α-Synuclein Fibrillation Process. Parkinson's disease. 2010 Jan; 2010(?):650794. doi: 10.4061/2010/650794. [PMID: 20976092]
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  • Eva Miadoková. Isoflavonoids - an overview of their biological activities and potential health benefits. Interdisciplinary toxicology. 2009 Dec; 2(4):211-8. doi: 10.2478/v10102-009-0021-3. [PMID: 21217857]
  • Bathilde Auger, Cécile Baron, Marie-Odile Lucas, Sonia Vautrin, Hélène Bergès, Boulos Chalhoub, Alain Fautrel, Michel Renard, Nathalie Nesi. Brassica orthologs from BANYULS belong to a small multigene family, which is involved in procyanidin accumulation in the seed. Planta. 2009 Nov; 230(6):1167-83. doi: 10.1007/s00425-009-1017-0. [PMID: 19760260]
  • Maki Jitsuno, Akihito Yokosuka, Hiroshi Sakagami, Yoshihiro Mimaki. Chemical constituents of the bulbs of Habranthus brachyandrus and their cytotoxic activities. Chemical & pharmaceutical bulletin. 2009 Oct; 57(10):1153-7. doi: 10.1248/cpb.57.1153. [PMID: 19801880]
  • Ayako Ikegami, Takashi Akagi, Daniel Potter, Masahiko Yamada, Akihiko Sato, Keizo Yonemori, Akira Kitajima, Kentaro Inoue. Molecular identification of 1-Cys peroxiredoxin and anthocyanidin/flavonol 3-O-galactosyltransferase from proanthocyanidin-rich young fruits of persimmon (Diospyros kaki Thunb.). Planta. 2009 Sep; 230(4):841-55. doi: 10.1007/s00425-009-0989-0. [PMID: 19641937]
  • Ryusuke Fudouji, Takashi Tanaka, Toshitugu Taguri, Yosuke Matsuo, Isao Kouno. Coupling reactions of catechins with natural aldehydes and allyl alcohols and radical scavenging activities of the triglyceride-soluble products. Journal of agricultural and food chemistry. 2009 Jul; 57(14):6417-24. doi: 10.1021/jf9010998. [PMID: 19537756]
  • Noppadon Rangkaew, Rutt Suttisri, Masataka Moriyasu, Kazuko Kawanishi. A new acyclic diterpene acid and bioactive compounds from Knema glauca. Archives of pharmacal research. 2009 May; 32(5):685-92. doi: 10.1007/s12272-009-1506-5. [PMID: 19471882]
  • Miao-Xian Su, Zhi-Yue Tang, Wei-Huan Huang, Yao-Lan Li, Ying-Zhou Cen. [Studies on the chemical comstituents of Pithecellobium clypearia]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2009 May; 32(5):705-7. doi: ". [PMID: 19771841]
  • Kashmir Singh, Arti Rani, Sanjay Kumar, Payal Sood, Monika Mahajan, Sudesh K Yadav, Bikram Singh, Paramvir S Ahuja. An early gene of the flavonoid pathway, flavanone 3-hydroxylase, exhibits a positive relationship with the concentration of catechins in tea (Camellia sinensis). Tree physiology. 2008 Sep; 28(9):1349-56. doi: 10.1093/treephys/28.9.1349. [PMID: 18595847]
  • Xiao-Qiu Liu, Li-Li Du, Wei-Wei Li, Hong-Feng Guan, Fang Liu. Simultaneous qualitative and quantitative analysis of commercial bistorta rhizome and its differentiation from closely related herbs using TLC and HPLC-DAD fingerprinting. Chemical & pharmaceutical bulletin. 2008 Jan; 56(1):75-8. doi: 10.1248/cpb.56.75. [PMID: 18175979]
  • Houhua Li, Henryk Flachowsky, Thilo C Fischer, Magda-Viola Hanke, Gert Forkmann, Dieter Treutter, Wilfried Schwab, Thomas Hoffmann, Iris Szankowski. Maize Lc transcription factor enhances biosynthesis of anthocyanins, distinct proanthocyanidins and phenylpropanoids in apple (Malus domestica Borkh.). Planta. 2007 Oct; 226(5):1243-54. doi: 10.1007/s00425-007-0573-4. [PMID: 17618453]
  • Shoko Taniguchi, Kayo Kuroda, Kou-ichi Doi, Kazutoshi Inada, Naomi Yoshikado, Yuji Yoneda, Masahiro Tanabe, Takashi Shibata, Takashi Yoshida, Tsutomu Hatano. [Evaluation of gambir quality based on quantitative analysis of polyphenolic constituents]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2007 Aug; 127(8):1291-300. doi: 10.1248/yakushi.127.1291. [PMID: 17666883]
  • Julius Oben, Dieudonne Kuate, Gabriel Agbor, Claudia Momo, Xavio Talla. The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids in health and disease. 2006 Sep; 5(?):24. doi: 10.1186/1476-511x-5-24. [PMID: 16948861]
  • Yaolan Li, Kam-Tong Leung, Fenghe Yao, Linda S M Ooi, Vincent E C Ooi. Antiviral flavans from the leaves of Pithecellobium clypearia. Journal of natural products. 2006 May; 69(5):833-5. doi: 10.1021/np050498o. [PMID: 16724853]
  • Esperanza J Carcache-Blanco, Muriel Cuendet, Eun Jung Park, Bao-Ning Su, J Fausto Rivero-Cruz, Norman R Farnsworth, John M Pezzuto, A Douglas Kinghorn. Potential cancer chemopreventive agents from Arbutus unedo. Natural product research. 2006 Apr; 20(4):327-34. doi: 10.1080/14786410500161205. [PMID: 16644527]
  • Madelyn Bekker, Riaan Bekker, Vincent E Brandt. Two flavonoid glycosides and a miscellaneous flavan from the bark of Guibourtia coleosperma. Phytochemistry. 2006 Apr; 67(8):818-23. doi: 10.1016/j.phytochem.2006.01.015. [PMID: 16494906]
  • De-Yu Xie, Shashi B Sharma, Elane Wright, Zeng-Yu Wang, Richard A Dixon. Metabolic engineering of proanthocyanidins through co-expression of anthocyanidin reductase and the PAP1 MYB transcription factor. The Plant journal : for cell and molecular biology. 2006 Mar; 45(6):895-907. doi: 10.1111/j.1365-313x.2006.02655.x. [PMID: 16507081]
  • Junko Takashima, Kanki Komiyama, Haruaki Ishiyama, Jun'ichi Kobayashi, Ayumi Ohsaki. Brosimacutins J-M, four new flavonoids from Brosimum acutifolium and their cytotoxic activity. Planta medica. 2005 Jul; 71(7):654-8. doi: 10.1055/s-2005-871272. [PMID: 16041652]
  • Wei Zhang, WeiDong Zhang, TingZhao Li, RunHui Liu, HuiLiang Li, HaiSheng Chen. A new flavan from Daphne odora var. atrocaulis. Fitoterapia. 2004 Dec; 75(7-8):799-800. doi: 10.1016/j.fitote.2004.09.014. [PMID: 15567270]
  • P A N Punyasiri, I S B Abeysinghe, V Kumar, D Treutter, D Duy, C Gosch, S Martens, G Forkmann, T C Fischer. Flavonoid biosynthesis in the tea plant Camellia sinensis: properties of enzymes of the prominent epicatechin and catechin pathways. Archives of biochemistry and biophysics. 2004 Nov; 431(1):22-30. doi: 10.1016/j.abb.2004.08.003. [PMID: 15464723]
  • Nancy Garbacki, Monique Tits, Luc Angenot, Jacques Damas. Inhibitory effects of proanthocyanidins from Ribes nigrum leaves on carrageenin acute inflammatory reactions induced in rats. BMC pharmacology. 2004 Oct; 4(?):25. doi: 10.1186/1471-2210-4-25. [PMID: 15498105]
  • Somdej Kanokmedhakul, Kwanjai Kanokmedhakul, Komkrich Nambuddee, Palangpon Kongsaeree. New bioactive prenylflavonoids and dibenzocycloheptene derivative from roots of Dendrolobium lanceolatum. Journal of natural products. 2004 Jun; 67(6):968-72. doi: 10.1021/np030519j. [PMID: 15217275]
  • Berhanu M Abegaz, Bonaventure T Ngadjui, Gabriel N Folefoc, Serge Fotso, Pantaleon Ambassa, Merhatibeb Bezabih, Etienne Dongo, Frode Rise, Dirk Petersen. Prenylated flavonoids, monoterpenoid furanocoumarins and other constituents from the twigs of Dorstenia elliptica (Moraceae). Phytochemistry. 2004 Jan; 65(2):221-6. doi: 10.1016/j.phytochem.2003.10.028. [PMID: 14732282]
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