Bicine (BioDeep_00000017892)

   

human metabolite Endogenous


代谢物信息卡片


N,N-Bis(2-hydroxyethyl)glycine, monosodium salt

化学式: C6H13NO4 (163.0844538)
中文名称: N,N-双(2-羟乙基)甘氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CO)N(CCO)CC(=O)O
InChI: InChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)

描述信息

Bicine is a general purpose buffer for biological research. Useful pH range is 7.6 - 9.0. Its applications include: tissue culture,phosphorylation and photophosphorylation, fixative transmission electron microscopy, protein synthesis and preventing binding to non-receptor materials. It is a degradation product of alkanolamine and alkylalkanolamine solutions. [HMDB]
. Bicine is a general purpose buffer for biological research. Useful pH range is 7.6 - 9.0. Its applications include: tissue culture,phosphorylation and photophosphorylation, fixative transmission electron microscopy, protein synthesis and preventing binding to non-receptor materials. It is a degradation product of alkanolamine and alkylalkanolamine solutions.

同义名列表

22 个代谢物同义名

N,N-Bis(2-hydroxyethyl)glycine, monosodium salt; N,N-Bis(2-hydroxyethyl)glycine, sodium salt; 2-(Bis(2-hydroxyethyl)amino)acetic acid; [Bis(2-hydroxyethyl)ammonio]acetic acid; 2-[bis(2-hydroxyethyl)amino]acetic acid; N,N-Bis(beta-hydroxyethyl)glycine; N,N-Bis(2-hydroxyethyl)glycine]; N,N-Bis(2-hydroxyethyl)-glycine; N,N-Bis(2-hydroxyethyl)glycine; N,N-(2-Dihydroxyethyl)glycine; N,N-Di(2-hydroxyethyl)glycine; N,N-Bis(hydroxyethyl)glycine; N,N-(2-Hydroxyethyl)glycine; N,N-Dihydroxyethyl glycine; Bis(2-hydroxyethyl)glycine; N,N-Dihydroxyethylglycine; Dihydroxyethylglycine; Diethanol glycine; Diethylolglycine; Bicine buffer; Bicine; Bicene



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Patrícia Diogo, Gil Martins, Rita Nogueira, Ana Marreiros, Paulo J Gavaia, Elsa Cabrita. Cryoprotectants synergy improve zebrafish sperm cryopreservation and offspring skeletogenesis. Cryobiology. 2019 12; 91(?):115-127. doi: 10.1016/j.cryobiol.2019.10.001. [PMID: 31605703]
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  • Ali Mobasheri, Elisa Trujillo, Mari-Francis Arteaga, Pablo Martín-Vasallo. Na(+), K(+)-ATPase subunit composition in a human chondrocyte cell line; evidence for the presence of α1, α3, β1, β2 and β3 isoforms. International journal of molecular sciences. 2012; 13(4):5019-34. doi: 10.3390/ijms13045019. [PMID: 22606027]
  • Barbara Nesta, Glen Spraggon, Christopher Alteri, Danilo Gomes Moriel, Roberto Rosini, Daniele Veggi, Sara Smith, Isabella Bertoldi, Ilaria Pastorello, Ilaria Ferlenghi, Maria Rita Fontana, Gad Frankel, Harry L T Mobley, Rino Rappuoli, Mariagrazia Pizza, Laura Serino, Marco Soriani. FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections. mBio. 2012; 3(2):. doi: 10.1128/mbio.00010-12. [PMID: 22496310]
  • Anne E Chambers, Krishnaveni P Nayini, Walter E Mills, Gillian M Lockwood, Subhasis Banerjee. Circulating LH/hCG receptor (LHCGR) may identify pre-treatment IVF patients at risk of OHSS and poor implantation. Reproductive biology and endocrinology : RB&E. 2011 Dec; 9(?):161. doi: 10.1186/1477-7827-9-161. [PMID: 22195987]
  • Nady Braidy, Gilles J Guillemin, Hussein Mansour, Tailoi Chan-Ling, Anne Poljak, Ross Grant. Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. PloS one. 2011 Apr; 6(4):e19194. doi: 10.1371/journal.pone.0019194. [PMID: 21541336]
  • Yoshiteru Seo, Keitaro Satoh, Kazuto Watanabe, Hironobu Morita, Akira Takamata, Takashi Ogino, Masataka Murakami. Mn-bicine: a low affinity chelate for manganese ion enhanced MRI. Magnetic resonance in medicine. 2011 Apr; 65(4):1005-12. doi: 10.1002/mrm.22680. [PMID: 21413064]
  • Alessandro Botton, Giulia Eccher, Claudio Forcato, Alberto Ferrarini, Maura Begheldo, Monica Zermiani, Stefano Moscatello, Alberto Battistelli, Riccardo Velasco, Benedetto Ruperti, Angelo Ramina. Signaling pathways mediating the induction of apple fruitlet abscission. Plant physiology. 2011 Jan; 155(1):185-208. doi: 10.1104/pp.110.165779. [PMID: 21037112]
  • P Pérez, G Rabnecz, Z Laufer, D Gutiérrez, Z Tuba, R Martínez-Carrasco. Restoration of photosystem II photochemistry and carbon assimilation and related changes in chlorophyll and protein contents during the rehydration of desiccated Xerophyta scabrida leaves. Journal of experimental botany. 2011 Jan; 62(3):895-905. doi: 10.1093/jxb/erq317. [PMID: 20956360]
  • Jeroni Galmés, Miquel Ribas-Carbó, Hipólito Medrano, Jaume Flexas. Rubisco activity in Mediterranean species is regulated by the chloroplastic CO2 concentration under water stress. Journal of experimental botany. 2011 Jan; 62(2):653-65. doi: 10.1093/jxb/erq303. [PMID: 21115663]
  • Yajuan Zhu, Wei Zhang, Natacha Veerapen, Gurdyal Besra, Peter Cresswell. Calreticulin controls the rate of assembly of CD1d molecules in the endoplasmic reticulum. The Journal of biological chemistry. 2010 Dec; 285(49):38283-92. doi: 10.1074/jbc.m110.170530. [PMID: 20861015]
  • Sven A Kranz, Orly Levitan, Klaus-Uwe Richter, Ondrej Prásil, Ilana Berman-Frank, Björn Rost. Combined effects of CO2 and light on the N2-fixing cyanobacterium Trichodesmium IMS101: physiological responses. Plant physiology. 2010 Sep; 154(1):334-45. doi: 10.1104/pp.110.159145. [PMID: 20625004]
  • Harriet V Hunt, Kay Denyer, Len C Packman, Martin K Jones, Christopher J Howe. Molecular basis of the waxy endosperm starch phenotype in broomcorn millet (Panicum miliaceum L.). Molecular biology and evolution. 2010 Jul; 27(7):1478-94. doi: 10.1093/molbev/msq040. [PMID: 20139147]
  • Giovanni Murtas. Internal lipid synthesis and vesicle growth as a step toward self-reproduction of the minimal cell. Systems and synthetic biology. 2010 Jun; 4(2):85-93. doi: 10.1007/s11693-009-9048-1. [PMID: 19957048]
  • Luciano Freschi, Maria Aurineide Rodrigues, Douglas Silva Domingues, Eduardo Purgatto, Marie-Anne Van Sluys, Jose Ronaldo Magalhaes, Werner M Kaiser, Helenice Mercier. Nitric oxide mediates the hormonal control of Crassulacean acid metabolism expression in young pineapple plants. Plant physiology. 2010 Apr; 152(4):1971-85. doi: 10.1104/pp.109.151613. [PMID: 20147491]
  • Sandesh Subramanya, Kojo Mensa-Wilmot. Diacylglycerol-stimulated endocytosis of transferrin in trypanosomatids is dependent on tyrosine kinase activity. PloS one. 2010 Jan; 5(1):e8538. doi: 10.1371/journal.pone.0008538. [PMID: 20049089]
  • Filippo Caschera, Gianluca Gazzola, Mark A Bedau, Carolina Bosch Moreno, Andrew Buchanan, James Cawse, Norman Packard, Martin M Hanczyc. Automated discovery of novel drug formulations using predictive iterated high throughput experimentation. PloS one. 2010 Jan; 5(1):e8546. doi: 10.1371/journal.pone.0008546. [PMID: 20049327]
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  • Nicole R Herring, Tori L Schaefer, Peter H Tang, Matthew R Skelton, James P Lucot, Gary A Gudelsky, Charles V Vorhees, Michael T Williams. Comparison of time-dependent effects of (+)-methamphetamine or forced swim on monoamines, corticosterone, glucose, creatine, and creatinine in rats. BMC neuroscience. 2008 May; 9(?):49. doi: 10.1186/1471-2202-9-49. [PMID: 18513404]
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  • Hong Zhao, Karen Yang, Anthony Martinez, Amartya Basu, Ramesh Chintala, Hsien-Ching Liu, Ahsen Janjua, Maoliang Wang, David Filpula. Linear and branched bicin linkers for releasable PEGylation of macromolecules: controlled release in vivo and in vitro from mono- and multi-PEGylated proteins. Bioconjugate chemistry. 2006 Mar; 17(2):341-51. doi: 10.1021/bc050270c. [PMID: 16536464]
  • Mohamed Taha. Buffers for the physiological pH range: acidic dissociation constants of zwitterionic compounds in various hydroorganic media. Annali di chimica. 2005 Jan; 95(1-2):105-9. doi: 10.1002/adic.200590001. [PMID: 15801182]
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  • S Ito, T Takaoka, H Mori, A Teruo. A sensitive new method for measurement of guanase with 8-azaguanine in bicine bis-hydroxy ethyl glycine buffer as substrate. Clinica chimica acta; international journal of clinical chemistry. 1981 Sep; 115(2):135-44. doi: 10.1016/0009-8981(81)90069-3. [PMID: 7285360]