Ethyl-isopropyl ether (BioDeep_00000178892)
human metabolite blood metabolite
代谢物信息卡片
2-methyl-2-[(2-methylbutan-2-yl)oxy]butane
化学式: C10H22O (158.1670562)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)(C)OC(C)(C)CC
InChI: InChI=1S/C10H22O/c1-7-9(3,4)11-10(5,6)8-2/h7-8H2,1-6H3
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Béatrice Gleize, Marlène Steib, Marc André, Emmanuelle Reboul. Simple and fast HPLC method for simultaneous determination of retinol, tocopherols, coenzyme Q(10) and carotenoids in complex samples.
Food chemistry.
2012 Oct; 134(4):2560-4. doi:
10.1016/j.foodchem.2012.04.043. [PMID: 22871234] - Shuming Yang, Panayiotis Savvides, Lili Liu, Stanton L Gerson, Yan Xu. Development and validation of an LC-MS/MS method for pharmacokinetic study of methoxyamine in phase I clinical trial.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Jul; 901(?):25-33. doi:
10.1016/j.jchromb.2012.05.036. [PMID: 22743337] - Hao Jiang, Jianing Zeng, Hamza Kandoussi, Yifei Liu, Xiaodong Wang, Marc Bifano, Laura Cojocaru, John Ryan, Mark E Arnold. A sensitive and accurate liquid chromatography-tandem mass spectrometry method for quantitative determination of the novel hepatitis C NS5A inhibitor BMS-790052 (daclastasvir) in human plasma and urine.
Journal of chromatography. A.
2012 Jul; 1245(?):117-21. doi:
10.1016/j.chroma.2012.05.028. [PMID: 22640838] - Seul Kee Byeon, Ju Yong Lee, Myeong Hee Moon. Optimized extraction of phospholipids and lysophospholipids for nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry.
The Analyst.
2012 Jan; 137(2):451-8. doi:
10.1039/c1an15920h. [PMID: 22108841] - Weijun Wang, Paul J Russell, Graeme T Clark, Derek Lewis, Kun Nang Cheng. A validated bioanalytical method in mouse, rat, rabbit and human plasma for the quantification of one of the steroid glycosides found in Hoodia gordonii extract.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Jan; 50 Suppl 1(?):S14-9. doi:
10.1016/j.fct.2010.08.014. [PMID: 20800086] - Saskia Floerl, Andrzej Majcherczyk, Mareike Possienke, Kirstin Feussner, Hella Tappe, Christiane Gatz, Ivo Feussner, Ursula Kües, Andrea Polle. Verticillium longisporum infection affects the leaf apoplastic proteome, metabolome, and cell wall properties in Arabidopsis thaliana.
PloS one.
2012; 7(2):e31435. doi:
10.1371/journal.pone.0031435. [PMID: 22363647] - Mauricio Henriques Pontes, Kari Lyn Smith, Linda De Vooght, Jan Van Den Abbeele, Colin Dale. Attenuation of the sensing capabilities of PhoQ in transition to obligate insect-bacterial association.
PLoS genetics.
2011 Nov; 7(11):e1002349. doi:
10.1371/journal.pgen.1002349. [PMID: 22072980] - Ajay Gupta, Puran Singhal, Pranav S Shrivastav, Mallika Sanyal. Application of a validated ultra performance liquid chromatography-tandem mass spectrometry method for the quantification of darunavir in human plasma for a bioequivalence study in Indian subjects.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Aug; 879(24):2443-53. doi:
10.1016/j.jchromb.2011.07.008. [PMID: 21788160] - Tatiana O Ajimura, Keyller B Borges, Aline F Ferreira, Fabíola A de Castro, Cristiane M de Gaitani. Capillary electrophoresis method for plasmatic determination of imatinib mesylate in chronic myeloid leukemia patients.
Electrophoresis.
2011 Jul; 32(14):1885-92. doi:
10.1002/elps.201000642. [PMID: 21710556] - S Halde, A Mungantiwar, M Chintamaneni. Simple, precise and accurate HPLC method of analysis for nevirapine suspension from human plasma.
Indian journal of pharmaceutical sciences.
2011 Jul; 73(4):416-21. doi:
10.4103/0250-474x.95626. [PMID: 22707826] - Kimberly M Jeckel, Kelsey E Miller, Adam J Chicco, Phillip L Chapman, Christopher M Mulligan, Paul H Falcone, Melissa L Miller, Michael J Pagliassotti, Melinda A Frye. The role of dietary fatty acids in predicting myocardial structure in fat-fed rats.
Lipids in health and disease.
2011 Jun; 10(?):92. doi:
10.1186/1476-511x-10-92. [PMID: 21649916] - André Macherius, Peter Kuschk, Claus Haertig, Monika Moeder, Natalia I Shtemenko, Antonio Heredia Bayona, José A Heredia Guerrero, Manfred Gey. Composition changes in the cuticular surface lipids of the helophytes Phragmites australis and Juncus effusus as result of pollutant exposure.
Environmental science and pollution research international.
2011 Jun; 18(5):727-33. doi:
10.1007/s11356-010-0416-x. [PMID: 21107744] - Jayesh G Panchal, Ravindra V Patel, Shobhana K Menon. Development and validation of GC/MS method for determination of pramipexole in rat plasma.
Biomedical chromatography : BMC.
2011 Apr; 25(4):524-30. doi:
10.1002/bmc.1478. [PMID: 20648686] - Jun Qian, Yixuan Wang, Jianhua Chang, Jian Zhang, Jialei Wang, Xichun Hu. Rapid and sensitive determination of vinorelbine in human plasma by liquid chromatography-tandem mass spectrometry and its pharmacokinetic application.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Mar; 879(9-10):662-8. doi:
10.1016/j.jchromb.2011.01.039. [PMID: 21342795] - Dipti Mangal, Cornelius E Uboh, Lawrence R Soma. Analysis of bioactive eicosanoids in equine plasma by stable isotope dilution reversed-phase liquid chromatography/multiple reaction monitoring mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2011 Mar; 25(5):585-98. doi:
10.1002/rcm.4893. [PMID: 21290445] - Timothy W Chow, András Szeitz, Dan W Rurak, K Wayne Riggs. A validated enantioselective assay for the simultaneous quantitation of (R)-, (S)-fluoxetine and (R)-, (S)-norfluoxetine in ovine plasma using liquid chromatography with tandem mass spectrometry (LC/MS/MS).
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Feb; 879(5-6):349-58. doi:
10.1016/j.jchromb.2010.12.020. [PMID: 21242112] - Manish Yadav, Chirag Patel, Mahendra Patel, Tulsidas Mishra, Girin A Baxi, Puran Singhal, Pranav S Shrivastav. Development and validation of a sensitive and rapid method to determine naratriptan in human plasma by LC-ESI-MS-MS: application to a bioequivalence study.
Journal of chromatographic science.
2011 Feb; 49(2):101-7. doi:
10.1093/chrsci/49.2.101. [PMID: 21223633] - Sudha P, Smita S Zinjarde, Shobha Y Bhargava, Ameeta R Kumar. Potent α-amylase inhibitory activity of Indian Ayurvedic medicinal plants.
BMC complementary and alternative medicine.
2011 Jan; 11(?):5. doi:
10.1186/1472-6882-11-5. [PMID: 21251279] - Jan Hummel, Shruthi Segu, Yan Li, Susann Irgang, Jessica Jueppner, Patrick Giavalisco. Ultra performance liquid chromatography and high resolution mass spectrometry for the analysis of plant lipids.
Frontiers in plant science.
2011; 2(?):54. doi:
10.3389/fpls.2011.00054. [PMID: 22629264] - Amina Ibrahim, Anna-Lena Schütz, Jean-Marie Galano, Cornelia Herrfurth, Kirstin Feussner, Thierry Durand, Florian Brodhun, Ivo Feussner. The Alphabet of Galactolipids in Arabidopsis thaliana.
Frontiers in plant science.
2011; 2(?):95. doi:
10.3389/fpls.2011.00095. [PMID: 22639619] - Céline Fernandez, Kai Schuhmann, Ronny Herzog, Barbara Fielding, Keith Frayn, Andrej Shevchenko, Peter James, Cecilia Holm, Kristoffer Ström. Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice.
PloS one.
2011; 6(6):e21603. doi:
10.1371/journal.pone.0021603. [PMID: 21738729] - Mohammad Aboulwafa, Milton H Saier. Biophysical studies of the membrane-embedded and cytoplasmic forms of the glucose-specific Enzyme II of the E. coli phosphotransferase system (PTS).
PloS one.
2011; 6(9):e24088. doi:
10.1371/journal.pone.0024088. [PMID: 21935376] - Sandra M Axiak, Kim A Selting, Charles J Decedue, Carolyn J Henry, Deborah Tate, Jahna Howell, K James Bilof, Dae Y Kim. Phase I dose escalation safety study of nanoparticulate paclitaxel (CTI 52010) in normal dogs.
International journal of nanomedicine.
2011; 6(?):2205-12. doi:
10.2147/ijn.s24823. [PMID: 22072863] - Harshica Fernando, Shakuntala Kondraganti, Kamlesh K Bhopale, David E Volk, Muniasamy Neerathilingam, Bhupendra S Kaphalia, Bruce A Luxon, Paul J Boor, G A Shakeel Ansari. ¹H and ³¹P NMR lipidome of ethanol-induced fatty liver.
Alcoholism, clinical and experimental research.
2010 Nov; 34(11):1937-47. doi:
10.1111/j.1530-0277.2010.01283.x. [PMID: 20682011] - Roongnapa Apinan, Anuruk Choemung, Kesara Na-Bangchang. A sensitive HPLC-ESI-MS-MS method for the determination of cotinine in urine.
Journal of chromatographic science.
2010 Jul; 48(6):460-5. doi:
10.1093/chromsci/48.6.460. [PMID: 20822661] - T R Schoeb, E E McConnell, M M Juliana, J K Davis, M K Davidson, J R Lindsey. Mycoplasma pulmonis and lymphoma in bioassays in rats.
Veterinary pathology.
2009 Sep; 46(5):952-9. doi:
10.1354/vp.08-vp-0240-s-com. [PMID: 19430000] - Juergen Graessler, Dominik Schwudke, Peter E H Schwarz, Ronny Herzog, Andrej Shevchenko, Stefan R Bornstein. Top-down lipidomics reveals ether lipid deficiency in blood plasma of hypertensive patients.
PloS one.
2009 Jul; 4(7):e6261. doi:
10.1371/journal.pone.0006261. [PMID: 19603071] - Ana Leonor Pardo Campos Godoy, Caio Cesar Parisi, Maria Paula Marques, Eduardo Barbosa Coelho, Vera Lucia Lanchote. Enantioselective determination of mexiletine and its metabolites p-hydroxymexiletine and hydroxymethylmexiletine in rat plasma by normal-phase liquid chromatography-tandem mass spectrometry: application to pharmacokinetics.
Chirality.
2009 Jul; 21(7):648-56. doi:
10.1002/chir.20650. [PMID: 18973279] - Bhavesh Dasandi, Sanjay Shah, Shivprakash. Development and validation of a high throughput and robust LC-MS/MS with electrospray ionization method for simultaneous quantitation of diltiazem and its two metabolites in human plasma: Application to a bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Mar; 877(8-9):791-8. doi:
10.1016/j.jchromb.2009.02.016. [PMID: 19237322] - Jin-Hee Park, Yoo-Sin Park, Si-Youn Rhim, Ok-Hwa Jhee, Shin-Hee Kim, Seok-Chul Yang, Min-Ho Lee, Leslie M Shaw, Ju-Seop Kang. Quantification of isradipine in human plasma using LC-MS/MS for pharmacokinetic and bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Jan; 877(1-2):59-64. doi:
10.1016/j.jchromb.2008.11.021. [PMID: 19041284] - Michael C Peoples, Matthew S Halquist, Omnia Ismaiel, Magda Y El-Mammli, Abdalla Shalaby, H Thomas Karnes. Assessment of matrix effects and determination of niacin in human plasma using liquid-liquid extraction and liquid chromatography-tandem mass spectrometry.
Biomedical chromatography : BMC.
2008 Nov; 22(11):1272-8. doi:
10.1002/bmc.1057. [PMID: 18651588] - Ann de Peyster, Yvonne Rodriguez, Rika Shuto, Beck Goldberg, Frank Gonzales, Xinzhu Pu, James E Klaunig. Effect of oral methyl-t-butyl ether (MTBE) on the male mouse reproductive tract and oxidative stress in liver.
Reproductive toxicology (Elmsford, N.Y.).
2008 Nov; 26(3-4):246-53. doi:
10.1016/j.reprotox.2008.08.009. [PMID: 18824092] - Zong-Zhu Piao, Eung-Seok Lee, Huyen Thi Thanh Tran, Beom-Jin Lee. Improved analytical validation and pharmacokinetics of valsartan using HPLC with UV detection.
Archives of pharmacal research.
2008 Aug; 31(8):1055-9. doi:
10.1007/s12272-001-1268-4. [PMID: 18787797] - Vitali Matyash, Gerhard Liebisch, Teymuras V Kurzchalia, Andrej Shevchenko, Dominik Schwudke. Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics.
Journal of lipid research.
2008 May; 49(5):1137-46. doi:
10.1194/jlr.d700041-jlr200. [PMID: 18281723] - Heon-Woo Lee, Ji-Hyung Seo, Hyun-Su Lee, Seo-Young Jeong, Young-Wuk Cho, Kyung-Tae Lee. Development of a liquid chromatography/negative-ion electrospray tandem mass spectrometry assay for the determination of cilnidipine in human plasma and its application to a bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2008 Feb; 862(1-2):246-51. doi:
10.1016/j.jchromb.2007.11.016. [PMID: 18155975] - Yuichi Miyake, Nobuyoshi Yamashita, Man Ka So, Pawel Rostkowski, Sachi Taniyasu, Paul K S Lam, Kurunthachalam Kannan. Trace analysis of total fluorine in human blood using combustion ion chromatography for fluorine: a mass balance approach for the determination of known and unknown organofluorine compounds.
Journal of chromatography. A.
2007 Jun; 1154(1-2):214-21. doi:
10.1016/j.chroma.2007.03.084. [PMID: 17416376] - Ashraf Ghanem, Ebtessam Al-Humaidi. Chiral recognition ability and solvent versatility of bonded amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phase: enantioselective liquid chromatographic resolution of racemic N-alkylated barbiturates and thalidomide analogs.
Chirality.
2007 Jun; 19(6):477-84. doi:
10.1002/chir.20398. [PMID: 17394130] - Hwi-Yeol Yun, Seong-Chul Bang, Ki-Cheol Lee, In-Hwan Baek, Seo-Pan Lee, Wonku Kang, Kwang-Il Kwon. Simultaneous analysis of naltrexone and its major metabolite, 6-beta-naltrexol, in human plasma using liquid chromatography-tandem mass spectrometry: Application to a parent-metabolite kinetic model in humans.
Talanta.
2007 Mar; 71(4):1553-9. doi:
10.1016/j.talanta.2006.07.035. [PMID: 19071491] - Marc P Fernandez, Michael G Ikonomou, Ian Buchanan. An assessment of estrogenic organic contaminants in Canadian wastewaters.
The Science of the total environment.
2007 Feb; 373(1):250-69. doi:
10.1016/j.scitotenv.2006.11.018. [PMID: 17197011] - R G Saĭfutdinov, O V Ryzhkova. [Contact chemical litholysis of gallbladder stones with methyl tert-butyl ether. Personal experience].
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology.
2007; ?(3):9-14, 128. doi:
. [PMID: 17939195] - In Bok Paek, Hye Young Ji, Maeng Seop Kim, Gwan Sun Lee, Hye Suk Lee. Simultaneous determination of paclitaxel and a new P-glycoprotein inhibitor HM-30181 in rat plasma by liquid chromatography with tandem mass spectrometry.
Journal of separation science.
2006 Mar; 29(5):628-34. doi:
10.1002/jssc.200500368. [PMID: 16605080] - Kyung-Hwan Yoon, So-Young Lee, Mi Jang, Sook-Hyun Ko, Won Kim, Jong-Sei Park, Insook Park, Hie-Joon Kim. A rapid determination of propiverine and its N-oxide metabolite in human plasma by high performance liquid chromatography-electrospray ionization tandem mass spectrometry.
Talanta.
2005 May; 66(4):831-6. doi:
10.1016/j.talanta.2004.12.055. [PMID: 18970060] - Hui-Hyun Kim, Hye Young Ji, Hye Won Lee, Youn-Chul Kim, Dong Hwan Sohn, Hye Suk Lee. Liquid chromatography-tandem mass spectrometry for the determination of lithospermic acid B in rat serum.
Archives of pharmacal research.
2004 Dec; 27(12):1202-6. doi:
10.1007/bf02975881. [PMID: 15646791] - M L Constanzer, C M Chavez-Eng, J Dru, W F Kline, B K Matuszewski. Determination of a novel substance P inhibitor in human plasma by high-performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometric detection using single and triple quadrupole detectors.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2004 Aug; 807(2):243-50. doi:
10.1016/j.jchromb.2004.04.017. [PMID: 15203036] - Mark M Kushnir, Rebecca Neilson, William L Roberts, Alan L Rockwood. Cortisol and cortisone analysis in serum and plasma by atmospheric pressure photoionization tandem mass spectrometry.
Clinical biochemistry.
2004 May; 37(5):357-62. doi:
10.1016/j.clinbiochem.2004.01.005. [PMID: 15087250] - Raymond F Suckow, Mira Fein, Christoph U Correll, Thomas B Cooper. Determination of plasma ziprasidone using liquid chromatography with fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2004 Jan; 799(2):201-8. doi:
10.1016/j.jchromb.2003.10.027. [PMID: 14670738] - Weng Naidong, Angela Eerkes. Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometric method for the analysis of paroxetine in human plasma.
Biomedical chromatography : BMC.
2004 Jan; 18(1):28-36. doi:
10.1002/bmc.288. [PMID: 14872546] - Yu-Luan Chen, Glenn D Hanson, Naidong Weng, Christopher Powala, Brad Zerler. Quantification of 6-deoxy-6-demethyl-4-dedimethylaminotetracycline (COL-3) in human plasma using liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2003 Aug; 794(1):77-88. doi:
10.1016/s1570-0232(03)00419-7. [PMID: 12888200] - Michael S Alexander, Melissa M Kiser, Travis Culley, John R Kern, John W Dolan, James D McChesney, Jan Zygmunt, Steve J Bannister. Measurement of paclitaxel in biological matrices: high-throughput liquid chromatographic-tandem mass spectrometric quantification of paclitaxel and metabolites in human and dog plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2003 Mar; 785(2):253-61. doi:
10.1016/s1570-0232(02)00913-3. [PMID: 12554138] - F Pommier, R Frigola. Quantitative determination of rivastigmine and its major metabolite in human plasma by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2003 Feb; 784(2):301-13. doi:
10.1016/s1570-0232(02)00816-4. [PMID: 12505778] - Helen K Jones, L E Stafford, H C Swaisland, R Payne. A sensitive assay for ZD1839 (Iressa) in human plasma by liquid-liquid extraction and high performance liquid chromatography with mass spectrometric detection: validation and use in Phase I clinical trials.
Journal of pharmaceutical and biomedical analysis.
2002 Jun; 29(1-2):221-8. doi:
10.1016/s0731-7085(02)00014-6. [PMID: 12062681] - Noriko Daneshtalab, Richard Z Lewanczuk, Fakhreddin Jamali. High-performance liquid chromatographic analysis of angiotensin II receptor antagonist valsartan using a liquid extraction method.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2002 Jan; 766(2):345-9. doi:
10.1016/s0378-4347(01)00507-2. [PMID: 11824822] - Amy Q Wang, Wei Zeng, D G Musson, J D Rogers, A L Fisher. A rapid and sensitive liquid chromatography/negative ion tandem mass spectrometry method for the determination of an indolocarbazole in human plasma using 96-well diatomaceous earth plates for solid-liquid extraction [correction of using internal standard (IS) 96-well diatomaceous earth plates for solid-liquid extraction].
Rapid communications in mass spectrometry : RCM.
2002; 16(10):975-81. doi:
10.1002/rcm.669. [PMID: 11968130] - M M Kushnir, G Komaromy-Hiller, B Shushan, F M Urry, W L Roberts. Analysis of dicarboxylic acids by tandem mass spectrometry. High-throughput quantitative measurement of methylmalonic acid in serum, plasma, and urine.
Clinical chemistry.
2001 Nov; 47(11):1993-2002. doi:
. [PMID: 11673368] - J S Brown, S M Bay, D J Greenstein, W R Ray. Concentrations of methyl- tert-butyl ether (MTBE) in inputs and receiving waters of Southern California.
Marine pollution bulletin.
2001 Oct; 42(10):957-66. doi:
10.1016/s0025-326x(01)00075-3. [PMID: 11693651]