Embutramide (BioDeep_00000178676)

   

human metabolite blood metabolite


代谢物信息卡片


N-(2-(3-Methoxyphenyl)-2-ethylbutyl-(1))-gamma-hydroxybutyramide

化学式: C17H27NO3 (293.1990832)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 50%

分子结构信息

SMILES: CCC(CC)(CNC(=O)CCCO)C1=CC(=CC=C1)OC
InChI: InChI=1S/C17H27NO3/c1-4-17(5-2,13-18-16(20)10-7-11-19)14-8-6-9-15(12-14)21-3/h6,8-9,12,19H,4-5,7,10-11,13H2,1-3H3,(H,18,20)

描述信息

C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent

同义名列表

5 个代谢物同义名

N-(2-(3-Methoxyphenyl)-2-ethylbutyl-(1))-gamma-hydroxybutyramide; N-[2-Ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxybutanimidate; N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxybutanamide; Embutramide; Embutane



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Anikó Lajtai, Mátyás Mayer, Ágnes Lakatos, Zoltán Porpáczy, Attila Miseta. Embutramide, a Component of Tanax(®) (T-61) as a New Drug of Abuse?. Journal of forensic sciences. 2016 Mar; 61(2):573-575. doi: 10.1111/1556-4029.13010. [PMID: 27404634]
  • Frank Musshoff, Katrin M Kirschbaum, Burkhard Madea. Another suicide using the veterinary drug T61 and distribution of drugs in the body. Journal of analytical toxicology. 2013 Apr; 37(3):186. doi: 10.1093/jat/bks140. [PMID: 23358154]
  • Katrin M Kirschbaum, Wolfgang Grellner, Gertrud Rochholz, Frank Musshoff, Burkhard Madea. Liquid chromatography-tandem mass spectrometry detection of the quaternary ammonium compound mebezonium as an active ingredient in t61. Journal of analytical toxicology. 2011 Mar; 35(2):124-8. doi: 10.1093/anatox/35.2.124. [PMID: 21396233]
  • Philippe Hantson, Antoine Villa, Anne-Cécile Galloy, Sara Negri, Giulia Esabon, Fabien Lambiotte, Vincent Haufroid, Robert Garnier. Dimethylformamide metabolism following self-harm using a veterinary euthanasia product. Clinical toxicology (Philadelphia, Pa.). 2010 Aug; 48(7):725-9. doi: 10.3109/15563650.2010.498790. [PMID: 20849330]
  • G Dickneite, I Pragst. Prothrombin complex concentrate vs fresh frozen plasma for reversal of dilutional coagulopathy in a porcine trauma model. British journal of anaesthesia. 2009 Mar; 102(3):345-54. doi: 10.1093/bja/aen391. [PMID: 19168856]
  • Emuri Abe, Anne-Sophie Lemaire-Hurtel, Charlotte Duverneuil, Isabelle Etting, Emmanuelle Guillot, Philippe de Mazancourt, Jean-Claude Alvarez. A novel LC-ESI-MS-MS method for sensitive quantification of colchicine in human plasma: application to two case reports. Journal of analytical toxicology. 2006 Apr; 30(3):210-5. doi: 10.1093/jat/30.3.210. [PMID: 16803656]
  • M Giorgi, S Bertini, G Soldani, M Giusiani. Comparison of HPLC and GC-MS methods for determination of embutramide (a component of Tanax or T-61) in biological specimens. Journal of analytical toxicology. 2001 Jul; 25(5):323-7. doi: 10.1093/jat/25.5.323. [PMID: 11499885]
  • J Z Huo, J Van Bocxlaer, W E Lambert, A P De Leenheer. Determination of embutramide in biological matrices by gas chromatography with nitrogen-phosphorus detection. Journal of chromatography. B, Biomedical applications. 1994 Nov; 661(1):69-74. doi: 10.1016/0378-4347(94)00318-1. [PMID: 7866553]
  • W E Braselton, J S Ray, M R Slanker, P C Rumler. Determination of embutramide in mammalian tissues. Veterinary and human toxicology. 1988 Dec; 30(6):536-9. doi: NULL. [PMID: 3245116]