Docosa-2,4,6,8,10-pentaenoic acid (BioDeep_00000178500)

   

human metabolite blood metabolite natural product


代谢物信息卡片


docosa-2,4,6,8,10-pentaenoic acid

  化学式: C22H34O2 (330.2559)
中文名称:
  谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: CCCCCCCCCCCC=CC=CC=CC=CC=CC(=O)O
InChI: InChI=1S/C22H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h12-21H,2-11H2,1H3,(H,23,24)


描述信息

同义名列表

2 个代谢物同义名

Docosa-2,4,6,8,10-pentaenoic acid; Docosapentaenoate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Nelís Soto-Ramírez, Wilfried Karmaus, Hongmei Zhang, Jihong Liu, Deborah Billings, Venugopal Gangur, David Amrol, Kerry-Ann da Costa, Susan Davis, Laura Goetzl. Fatty acids in breast milk associated with asthma-like symptoms and atopy in infancy: a longitudinal study. The Journal of asthma : official journal of the Association for the Care of Asthma. 2012 Nov; 49(9):926-34. doi: 10.3109/02770903.2012.719251. [PMID: 22991928]
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  • Fuxia Jin, David C Nieman, Wei Sha, Guoxiang Xie, Yunping Qiu, Wei Jia. Supplementation of milled chia seeds increases plasma ALA and EPA in postmenopausal women. Plant foods for human nutrition (Dordrecht, Netherlands). 2012 Jun; 67(2):105-10. doi: 10.1007/s11130-012-0286-0. [PMID: 22538527]
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  • Drake C Mitchell, Shui-Lin Niu, Burton J Litman. Quantifying the differential effects of DHA and DPA on the early events in visual signal transduction. Chemistry and physics of lipids. 2012 May; 165(4):393-400. doi: 10.1016/j.chemphyslip.2012.02.008. [PMID: 22405878]
  • Hua Liang Liu, Zhi Jie Yin, Li Xiao, Yi Nong Xu, Le Qing Qu. Identification and evaluation of ω-3 fatty acid desaturase genes for hyperfortifying α-linolenic acid in transgenic rice seed. Journal of experimental botany. 2012 May; 63(8):3279-87. doi: 10.1093/jxb/ers051. [PMID: 22378946]
  • Jingnan Chen, Yue Jiang, Yintong Liang, Xiaoyu Tian, Cheng Peng, Ka Ying Ma, Jian Liu, Yu Huang, Zhen-Yu Chen. DPA n-3, DPA n-6 and DHA improve lipoprotein profiles and aortic function in hamsters fed a high cholesterol diet. Atherosclerosis. 2012 Apr; 221(2):397-404. doi: 10.1016/j.atherosclerosis.2012.01.005. [PMID: 22284366]
  • C E Childs, S P Hoile, G C Burdge, P C Calder. Changes in rat n-3 and n-6 fatty acid composition during pregnancy are associated with progesterone concentrations and hepatic FADS2 expression. Prostaglandins, leukotrienes, and essential fatty acids. 2012 Apr; 86(4-5):141-7. doi: 10.1016/j.plefa.2012.03.007. [PMID: 22495065]
  • Mark K Waldron, Steven S Hannah, John E Bauer. Plasma phospholipid fatty acid and ex vivo neutrophil responses are differentially altered in dogs fed fish- and linseed-oil containing diets at the same n-6:n-3 fatty acid ratio. Lipids. 2012 Apr; 47(4):425-34. doi: 10.1007/s11745-012-3652-7. [PMID: 22252853]
  • Pedro F Almaida-Pagán, Jorge de Costa, Pilar Mendiola, Douglas R Tocher. Changes in tissue and mitochondrial membrane composition during rapid growth, maturation and aging in rainbow trout, Oncorhynchus mykiss. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2012 Apr; 161(4):404-12. doi: 10.1016/j.cbpb.2012.01.006. [PMID: 22281523]
  • Marie-Noëlle Delyfer, Benjamin Buaud, Jean-François Korobelnik, Marie-Bénédicte Rougier, Wolfgang Schalch, Stephane Etheve, Carole Vaysse, Nicole Combe, Mélanie Le Goff, Ute E K Wolf-Schnurrbusch, Sebastian Wolf, Pascale Barberger-Gateau, Cécile Delcourt. Association of macular pigment density with plasma ω-3 fatty acids: the PIMAVOSA study. Investigative ophthalmology & visual science. 2012 Mar; 53(3):1204-10. doi: 10.1167/iovs.11-8721. [PMID: 22273721]
  • Jason H Y Wu, Rozenn N Lemaitre, Irena B King, Xiaoling Song, Frank M Sacks, Eric B Rimm, Susan R Heckbert, David S Siscovick, Dariush Mozaffarian. Association of plasma phospholipid long-chain ω-3 fatty acids with incident atrial fibrillation in older adults: the cardiovascular health study. Circulation. 2012 Mar; 125(9):1084-93. doi: 10.1161/circulationaha.111.062653. [PMID: 22282329]
  • Edgar Weigand, Christine Boesch-Saadatmandi. Interaction between marginal zinc and high fat supply on lipid metabolism and growth of weanling rats. Lipids. 2012 Mar; 47(3):291-302. doi: 10.1007/s11745-011-3629-y. [PMID: 22127571]
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  • Miki Igarashi, Hyung-Wook Kim, Lisa Chang, Kaizong Ma, Stanley I Rapoport. Dietary n-6 polyunsaturated fatty acid deprivation increases docosahexaenoic acid metabolism in rat brain. Journal of neurochemistry. 2012 Mar; 120(6):985-97. doi: 10.1111/j.1471-4159.2011.07597.x. [PMID: 22117540]
  • D W Luchtman, Q Meng, C Song. Ethyl-eicosapentaenoate (E-EPA) attenuates motor impairments and inflammation in the MPTP-probenecid mouse model of Parkinson's disease. Behavioural brain research. 2012 Jan; 226(2):386-96. doi: 10.1016/j.bbr.2011.09.033. [PMID: 21971013]
  • Nicole Testerink, Mokrish Ajat, Martin Houweling, Jos F Brouwers, Vishnu V Pully, Henk-Jan van Manen, Cees Otto, J Bernd Helms, Arie B Vaandrager. Replacement of retinyl esters by polyunsaturated triacylglycerol species in lipid droplets of hepatic stellate cells during activation. PloS one. 2012; 7(4):e34945. doi: 10.1371/journal.pone.0034945. [PMID: 22536341]
  • Noelle N Gronroos, Alanna M Chamberlain, Aaron R Folsom, Elsayed Z Soliman, Sunil K Agarwal, Jennifer A Nettleton, Alvaro Alonso. Fish, fish-derived n-3 fatty acids, and risk of incident atrial fibrillation in the Atherosclerosis Risk in Communities (ARIC) study. PloS one. 2012; 7(5):e36686. doi: 10.1371/journal.pone.0036686. [PMID: 22570739]
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  • Marie Standl, Eva Lattka, Barbara Stach, Sibylle Koletzko, Carl-Peter Bauer, Andrea von Berg, Dietrich Berdel, Ursula Krämer, Beate Schaaf, Stefan Röder, Olf Herbarth, Anette Buyken, Tim Drogies, Joachim Thiery, Berthold Koletzko, Joachim Heinrich. FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children: results from the GINIplus and LISAplus studies. PloS one. 2012; 7(5):e37780. doi: 10.1371/journal.pone.0037780. [PMID: 22629455]
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  • Hyung-Wook Kim, Jagadeesh S Rao, Stanley I Rapoport, Miki Igarashi. Regulation of rat brain polyunsaturated fatty acid (PUFA) metabolism during graded dietary n-3 PUFA deprivation. Prostaglandins, leukotrienes, and essential fatty acids. 2011 Dec; 85(6):361-8. doi: 10.1016/j.plefa.2011.08.002. [PMID: 21880477]
  • P Guesnet, S-M Lallemand, J-M Alessandri, M Jouin, S C Cunnane. α-Linolenate reduces the dietary requirement for linoleate in the growing rat. Prostaglandins, leukotrienes, and essential fatty acids. 2011 Dec; 85(6):353-60. doi: 10.1016/j.plefa.2011.08.003. [PMID: 21880475]
  • Lisbeth Dahl, Camilla A Mæland, Tormod Bjørkkjær. A short food frequency questionnaire to assess intake of seafood and n-3 supplements: validation with biomarkers. Nutrition journal. 2011 Nov; 10(?):127. doi: 10.1186/1475-2891-10-127. [PMID: 22099052]
  • Yongsoon Park, Minkyung Kim. Serum 25-hydroxyvitamin D concentrations are associated with erythrocyte levels of n-3 PUFA but not risk of CVD. The British journal of nutrition. 2011 Nov; 106(10):1529-34. doi: 10.1017/s0007114511001930. [PMID: 21736802]
  • Stephan Winnik, Christine Lohmann, Eva K Richter, Nicola Schäfer, Wen-Liang Song, Florian Leiber, Pavani Mocharla, Janin Hofmann, Roland Klingenberg, Jan Borén, Burkhard Becher, Garret A Fitzgerald, Thomas F Lüscher, Christian M Matter, Jürg H Beer. Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation. European heart journal. 2011 Oct; 32(20):2573-84. doi: 10.1093/eurheartj/ehq501. [PMID: 21285075]
  • Preeti Purwaha, Yan Gu, Uddhav Kelavkar, Jing X Kang, Benedict Law, Erxi Wu, Steven Y Qian. LC/ESR/MS study of pH-dependent radical generation from 15-LOX-catalyzed DPA peroxidation. Free radical biology & medicine. 2011 Oct; 51(7):1461-70. doi: 10.1016/j.freeradbiomed.2011.07.001. [PMID: 21807091]
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