2,5-Diamino-4,5-diketopyrimidine (BioDeep_00000178452)
human metabolite blood metabolite
代谢物信息卡片
化学式: C4H6N4O2 (142.0490736)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 3.3%
分子结构信息
SMILES: C1(C(=O)C(=O)NC(=N1)N)N
InChI: InChI=1S/C4H6N4O2/c5-2-1(9)3(10)8-4(6)7-2/h2H,5H2,(H3,6,7,8,10)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Carlo Giuseppe Rizzello, Ilario Losito, Laura Facchini, Kati Katina, Francesco Palmisano, Marco Gobbetti, Rossana Coda. Degradation of vicine, convicine and their aglycones during fermentation of faba bean flour.
Scientific reports.
2016 08; 6(?):32452. doi:
10.1038/srep32452. [PMID: 27578427] - David C McMillan, Christine L Powell, Zachary S Bowman, Jason D Morrow, David J Jollow. Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 Nov; 88(1):274-83. doi:
10.1093/toxsci/kfi290. [PMID: 16107547] - D J Jollow, D C McMillan. Oxidative stress, glucose-6-phosphate dehydrogenase and the red cell.
Advances in experimental medicine and biology.
2001; 500(?):595-605. doi:
10.1007/978-1-4615-0667-6_88. [PMID: 11765001] - D C McMillan, D J Jollow. Favism: divicine hemotoxicity in the rat.
Toxicological sciences : an official journal of the Society of Toxicology.
1999 Oct; 51(2):310-6. doi:
10.1093/toxsci/51.2.310. [PMID: 10543033] - M Ferrali, C Signorini, B Caciotti, L Sugherini, L Ciccoli, D Giachetti, M Comporti. Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity.
FEBS letters.
1997 Oct; 416(2):123-9. doi:
10.1016/s0014-5793(97)01182-4. [PMID: 9369196] - M Ferrali, C Signorini, L Ciccoli, M Comporti. Iron release and membrane damage in erythrocytes exposed to oxidizing agents, phenylhydrazine, divicine and isouramil.
The Biochemical journal.
1992 Jul; 285 ( Pt 1)(?):295-301. doi:
10.1042/bj2850295. [PMID: 1637315] - A Vanella, A Campisi, C Castorina, V Sorrenti, G Attaguile, P Samperi, N Azzia, C Di Giacomo, G Schilirò. Antioxidant enzymatic systems and oxidative stress in erythrocytes with G6PD deficiency: effect of deferoxamine.
Pharmacological research.
1991 Jul; 24(1):25-31. doi:
10.1016/1043-6618(91)90061-2. [PMID: 1946141] - H P Monteiro, C C Winterbourn. Release of iron from ferritin by divicine, isouramil, acid-hydrolyzed vicine, and dialuric acid and initiation of lipid peroxidation.
Archives of biochemistry and biophysics.
1989 Jun; 271(2):536-45. doi:
10.1016/0003-9861(89)90305-6. [PMID: 2730003] - A De Flora, U Benatti, L Guida. The role of plasma in oxidative haemolysis.
Free radical research communications.
1986; 1(3):201-24. doi:
10.3109/10715768609083152. [PMID: 2577737] - T M Fischer, T Meloni, G P Pescarmona, P Arese. Membrane cross bonding in red cells in favic crisis: a missing link in the mechanism of extravascular haemolysis.
British journal of haematology.
1985 Jan; 59(1):159-69. doi:
10.1111/j.1365-2141.1985.tb02976.x. [PMID: 3970849] - I Mavelli, M R Ciriolo, L Rossi, T Meloni, G Forteleoni, A De Flora, U Benatti, A Morelli, G Rotilio. Favism: a hemolytic disease associated with increased superoxide dismutase and decreased glutathione peroxidase activities in red blood cells.
European journal of biochemistry.
1984 Feb; 139(1):13-8. doi:
10.1111/j.1432-1033.1984.tb07969.x. [PMID: 6698000] - A De Flora, U Benatti, A Morelli, L Guida. Oxidant damage of normal and glucose 6-phosphate dehydrogenase (G6PD)-deficient red blood cells is enhanced by iron-EDTA complex.
Biochemistry international.
1983 Sep; 7(3):281-90. doi:
. [PMID: 6089811]