Dithiophosphoric acid (BioDeep_00000178449)
human metabolite blood metabolite
代谢物信息卡片
Phosphorodithioic acid, zinc salt (2:1)
化学式: H3O2PS2 (129.9312108)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: OP(=S)(O)S
InChI: InChI=1S/H3O2PS2/c1-3(2,4)5/h(H3,1,2,4,5)
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:74944
- PubChem: 152119
- HMDB: HMDB0251495
- ChEMBL: CHEMBL4210072
- Wikipedia: Thiophosphate
- MetaCyc: CPD-3735
- chemspider: 134077
- CAS: 15834-33-0
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Tianning Pu, Jingdan Liang, Zhiling Mei, Yan Yang, Jialiang Wang, Wei Zhang, Wei-Jun Liang, Xiufen Zhou, Zixin Deng, Zhijun Wang. Phosphorothioated DNA Is Shielded from Oxidative Damage.
Applied and environmental microbiology.
2019 04; 85(8):. doi:
10.1128/aem.00104-19. [PMID: 30737351] - N Dinuka Abeydeera, Martin Egli, Nehemiah Cox, Karen Mercier, Jonas Nascimento Conde, Pradeep S Pallan, Daniella M Mizurini, Malgorzata Sierant, Fatima-Ezzahra Hibti, Tom Hassell, Tianzhi Wang, Feng-Wu Liu, Hong-Min Liu, Carlos Martinez, Anil K Sood, Terry P Lybrand, Chiraz Frydman, Robson Q Monteiro, Richard H Gomer, Barbara Nawrot, Xianbin Yang. Evoking picomolar binding in RNA by a single phosphorodithioate linkage.
Nucleic acids research.
2016 09; 44(17):8052-64. doi:
10.1093/nar/gkw725. [PMID: 27566147] - Montano Durso, Maria Gaglione, Linda Piras, Maria Emilia Mercurio, Sara Terreri, Michele Olivieri, Luciana Marinelli, Ettore Novellino, Mariarosaria Incoronato, Paolo Grieco, Gaetano Orsini, Giancarlo Tonon, Anna Messere, Amelia Cimmino. Chemical modifications in the seed region of miRNAs 221/222 increase the silencing performances in gastrointestinal stromal tumor cells.
European journal of medicinal chemistry.
2016 Mar; 111(?):15-25. doi:
10.1016/j.ejmech.2016.01.047. [PMID: 26854374] - Dan Wu, Qingxun Hu, Yizhun Zhu. Therapeutic application of hydrogen sulfide donors: the potential and challenges.
Frontiers of medicine.
2016 Mar; 10(1):18-27. doi:
10.1007/s11684-015-0427-6. [PMID: 26597301] - Mojtaba Fathi, Kamal Yavari, Mohammad Taghikhani, Mohammad Ghannadi Maragheh. Synthesis of a stabilized 177Lu-siRNA complex and evaluation of its stability and RNAi activity.
Nuclear medicine communications.
2015 Jun; 36(6):636-45. doi:
10.1097/mnm.0000000000000292. [PMID: 25759946] - Misuzu Tanaka, Keiko Ishii, Yuri Nakamura, Akiko Miyazato, Atsuko Maki, Yuzuru Abe, Tomomitsu Miyasaka, Hideki Yamamoto, Yukiko Akahori, Misaki Fue, Yurie Takahashi, Emi Kanno, Ryoko Maruyama, Kazuyoshi Kawakami. Toll-like receptor 9-dependent activation of bone marrow-derived dendritic cells by URA5 DNA from Cryptococcus neoformans.
Infection and immunity.
2012 Feb; 80(2):778-86. doi:
10.1128/iai.05570-11. [PMID: 22104112] - Surong Zhang, Guozheng Liu, Xinrong Liu, Dongguang Yin, Shuping Dou, Jiang He, Mary Rusckowski, Donald J Hnatowich. Comparison of several linear fluorophore- and quencher-conjugated oligomer duplexes for stability, fluorescence quenching, and kinetics in vitro and in vivo in mice.
Bioconjugate chemistry.
2007 Jul; 18(4):1170-5. doi:
10.1021/bc070021j. [PMID: 17511492] - Ali M Tamaddon, Farshad H Shirazi, Hamid R Moghimi. Modeling cytoplasmic release of encapsulated oligonucleotides from cationic liposomes.
International journal of pharmaceutics.
2007 May; 336(1):174-82. doi:
10.1016/j.ijpharm.2006.11.048. [PMID: 17196349] - Honglu Zhang, Nicolas Markadieu, Renaud Beauwens, Christophe Erneux, Glenn D Prestwich. Synthesis and biological activity of PTEN-resistant analogues of phosphatidylinositol 3,4,5-trisphosphate.
Journal of the American Chemical Society.
2006 Dec; 128(51):16464-5. doi:
10.1021/ja065002j. [PMID: 17177371] - Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Guido Marcucci, Kenneth K Chan. Metabolism of GTI-2040, a phosphorothioate oligonucleotide antisense, using ion-pair reversed phase high performance liquid chromatography (HPLC) coupled with electrospray ion-trap mass spectrometry.
The AAPS journal.
2006; 8(4):E743-55. doi:
10.1208/aapsj080484. [PMID: 17285740] - Su-Jun Zheng, Sen Zhong, Jian-Jun Zhang, Feng Chen, Hong Ren, Cun-Liang Deng. Distribution and anti-HBV effects of antisense oligodeoxynucleotides conjugated to galactosylated poly-L-lysine.
World journal of gastroenterology.
2003 Jun; 9(6):1251-5. doi:
10.3748/wjg.v9.i6.1251. [PMID: 12800234] - A N Oglobline, H Elimelakh, B Tattam, R Geyer, G E O'Donnell, G Holder. Negative ion chemical ionization GC/MS-MS analysis of dialkylphosphate metabolites of organophosphate pesticides in urine of non-occupationally exposed subjects.
The Analyst.
2001 Jul; 126(7):1037-41. doi:
10.1039/b102004h. [PMID: 11478632] - W R Epa, U Greferath, A Shafton, P Rong, L M Delbridge, A Bennie, G L Barrett. Downregulation of the p75 neurotrophin receptor in tissue culture and in vivo, using beta-cyclodextrin-adamantane-oligonucleotide conjugates.
Antisense & nucleic acid drug development.
2000 Dec; 10(6):469-78. doi:
10.1089/oli.1.2000.10.469. [PMID: 11198931] - P de Mazancourt, P K Goldsmith, L S Weinstein. Inhibition of adenylate cyclase activity by galanin in rat insulinoma cells is mediated by the G-protein Gi3.
The Biochemical journal.
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