Distearoyl phosphatidylglycerol (BioDeep_00000178440)
human metabolite blood metabolite
代谢物信息卡片
Octadecanoic acid, 1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl ester
化学式: C42H83O10P (778.5723548)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(CO)O)OC(=O)CCCCCCCCCCCCCCCCC
InChI: InChI=1S/C42H83O10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39-40,43-44H,3-38H2,1-2H3,(H,47,48)
描述信息
同义名列表
18 个代谢物同义名
Octadecanoic acid, 1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl ester; Octadecanoate, 1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl ester; [2,3-bis(octadecanoyloxy)propoxy](2,3-dihydroxypropoxy)phosphinic acid; Phosphoric acid mono-(2,3-bis-stearoyloxy-propyl ester); 1,2-Di-O-octadecanoyl-rac-3-glycerophosphoric acid; Phosphate mono-(2,3-bis-stearoyloxy-propyl ester); 1,2-Di-O-stearoyl-rac-3-glycerophosphoric acid; 1,2-Di-O-octadecanoyl-rac-3-glycerophosphate; 1,2-Di-O-stearoyl-rac-3-glycerophosphate; Distearoyl phosphatidylglycerol, sodium; 1,2-Distearoylphosphatidylglycerol; Dioctanoylphosphatididylglycerol; Distearoyl phosphatidylglycerol; Distearoylphoshatidylglycerol; Distearoyl PPG; C18:0 PG; 18:0 PG; DSPG
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Gabriel Silva Marques Borges, Thais Tunes Santos, Cristiane Monteiro Pinto, Frédéric Frézard, Verônica Freitas Blanco, Roberta Ondei, Stephen Rumbelow, Lucas Antônio Miranda Ferreira, Marta Marques Gontijo de Aguiar, Gisele Assis Castro Goulart. Distearoyl phosphatidylglycerol and dioleoyl phosphatidylglycerol increase the retention and reduce the toxicity of amphotericin B-loaded in nanoemulsions.
Nanomedicine (London, England).
2024 02; 19(5):383-396. doi:
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International journal of pharmaceutics.
2020 Nov; 590(?):119886. doi:
10.1016/j.ijpharm.2020.119886. [PMID: 32998031] - Johan Unga, Daiki Omata, Nobuki Kudo, Soki Ueno, Lisa Munakata, Tadamitsu Shima, Ryo Suzuki, Kazuo Maruyama. Development and evaluation of stability and ultrasound response of DSPC-DPSG-based freeze-dried microbubbles.
Journal of liposome research.
2019 Dec; 29(4):368-374. doi:
10.1080/08982104.2018.1556294. [PMID: 30526185] - Desiree Van Haute, Wenlei Jiang, Thilak Mudalige. Evaluation of size-based distribution of drug and excipient in amphotericin B liposomal formulation.
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International journal of nanomedicine.
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Journal of controlled release : official journal of the Controlled Release Society.
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10.1016/j.jconrel.2018.10.028. [PMID: 30365993] - Lisa Rahnfeld, Jana Thamm, Frank Steiniger, Peter van Hoogevest, Paola Luciani. Study on the in situ aggregation of liposomes with negatively charged phospholipids for use as injectable depot formulation.
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Nature communications.
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2016 Oct; 119(4):353-9. doi:
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PloS one.
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The journal of physical chemistry. B.
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The AAPS journal.
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Journal of colloid and interface science.
2007 Nov; 315(2):701-13. doi:
10.1016/j.jcis.2007.07.011. [PMID: 17655855] - Georg Pabst, Sabine Danner, Sanat Karmakar, Günter Deutsch, Velayudhan A Raghunathan. On the propensity of phosphatidylglycerols to form interdigitated phases.
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10.1016/j.bbamem.2004.07.005. [PMID: 15471581] - Oleg Konovalov, Igor Myagkov, Bernd Struth, Karl Lohner. Lipid discrimination in phospholipid monolayers by the antimicrobial frog skin peptide PGLa. A synchrotron X-ray grazing incidence and reflectivity study.
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10.1007/s00249-002-0233-3. [PMID: 12355252] - V Razumas, Z Talaikyte, J Barauskas, K Larsson, Y Miezis, T Nylander. Effects of distearoylphosphatidylglycerol and lysozyme on the structure of the monoolein-water cubic phase: X-ray diffraction and Raman scattering studies.
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