Diphenyl-1-pyrenylphosphine (BioDeep_00000178411)
human metabolite blood metabolite
代谢物信息卡片
diphenyl(pyren-1-yl)phosphane
化学式: C28H19P (386.12243040000004)
中文名称: 二苯基-1-芘基膦
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)P(C1=CC=CC=C1)C1=C2C=CC3=CC=CC4=C3C2=C(C=C4)C=C1
InChI: InChI=1S/C28H19P/c1-3-10-23(11-4-1)29(24-12-5-2-6-13-24)26-19-17-22-15-14-20-8-7-9-21-16-18-25(26)28(22)27(20)21/h1-19H
描述信息
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sibel Uluata, Gokhan Durmaz, D Julian McClements, Eric A Decker. Comparing DPPP fluorescence and UV based methods to assess oxidation degree of krill oil-in-water emulsions.
Food chemistry.
2021 Mar; 339(?):127898. doi:
10.1016/j.foodchem.2020.127898. [PMID: 32871303] - Mayuko Morita, Yuji Naito, Toshikazu Yoshikawa, Etsuo Niki. Plasma lipid oxidation induced by peroxynitrite, hypochlorite, lipoxygenase and peroxyl radicals and its inhibition by antioxidants as assessed by diphenyl-1-pyrenylphosphine.
Redox biology.
2016 08; 8(?):127-35. doi:
10.1016/j.redox.2016.01.005. [PMID: 26774081] - Mayuko Morita, Yuji Naito, Toshikazu Yoshikawa, Etsuo Niki. Rapid assessment of singlet oxygen-induced plasma lipid oxidation and its inhibition by antioxidants with diphenyl-1-pyrenylphosphine (DPPP).
Analytical and bioanalytical chemistry.
2016 Jan; 408(1):265-70. doi:
10.1007/s00216-015-9102-7. [PMID: 26466579] - Jonathan Santas, Yeimmy J Guzmán, Francesc Guardiola, Magdalena Rafecas, Ricard Bou. High-throughput analysis of lipid hydroperoxides in edible oils and fats using the fluorescent reagent diphenyl-1-pyrenylphosphine.
Food chemistry.
2014 Nov; 162(?):235-41. doi:
10.1016/j.foodchem.2014.04.059. [PMID: 24874381] - Tsuyoshi Tanaka, Mari Shimoda, Nozomi Shionoiri, Masahito Hosokawa, Tomoyuki Taguchi, Hitoshi Wake, Tadashi Matsunaga. Electrochemical disinfection of fish pathogens in seawater without the production of a lethal concentration of chlorine using a flow reactor.
Journal of bioscience and bioengineering.
2013 Oct; 116(4):480-4. doi:
10.1016/j.jbiosc.2013.04.013. [PMID: 23648105] - Jonathan Santas, Francesc Guardiola, Magda Rafecas, Ricard Bou. Determination of total plasma hydroperoxides using a diphenyl-1-pyrenylphosphine fluorescent probe.
Analytical biochemistry.
2013 Mar; 434(1):172-7. doi:
10.1016/j.ab.2012.11.021. [PMID: 23228567] - Kyoung Ah Kang, Rui Zhang, Mei Jing Piao, Sungwook Chae, Hee Sun Kim, Jun Ho Park, Kwang Sun Jung, Jin Won Hyun. Baicalein inhibits oxidative stress-induced cellular damage via antioxidant effects.
Toxicology and industrial health.
2012 Jun; 28(5):412-21. doi:
10.1177/0748233711413799. [PMID: 21957089] - Hitomi Okada, Yuji Naito, Tomohisa Takagi, Megumi Takaoka, Tomoko Oya-Ito, Kohei Fukumoto, Kazuhiko Uchiyama, Osamu Handa, Satoshi Kokura, Yumiko Nagano, Hirofumi Matsui, Yoji Kato, Toshihiko Osawa, Toshikazu Yoshikawa. Detection of N-(hexanoyl)lysine in the tropomyosin 1 protein in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric cancer cells.
Journal of clinical biochemistry and nutrition.
2012 Jan; 50(1):47-52. doi:
10.3164/jcbn.11-39. [PMID: 22247600] - Kanho Rai, Hirofumi Matsui, Tsuyoshi Kaneko, Yumiko Nagano, Osamu Shimokawa, Jumpei Udo, Aki Hirayama, Ichinosuke Hyodo, Hiroko P Indo, Hideyuki J Majima. Lansoprazole inhibits mitochondrial superoxide production and cellular lipid peroxidation induced by indomethacin in RGM1 cells.
Journal of clinical biochemistry and nutrition.
2011 Jul; 49(1):25-30. doi:
10.3164/jcbn.10-133. [PMID: 21765603] - Mei Jing Piao, Weon Jong Yoon, Hee Kyoung Kang, Eun Sook Yoo, Young Sang Koh, Dong Sam Kim, Nam Ho Lee, Jin Won Hyun. Protective effect of the ethyl acetate fraction of Sargassum muticum against ultraviolet B-irradiated damage in human keratinocytes.
International journal of molecular sciences.
2011; 12(11):8146-60. doi:
10.3390/ijms12118146. [PMID: 22174656] - Märta Dahlström, Daniel Forsström, Malin Johannesson, Yasmin Huque-Andersson, Marie Björk, Erik Silfverplatz, Andrei Sanin, Wesley Schaal, Benjamin Pelcman, Pontus K A Forsell. Development of a fluorescent intensity assay amenable for high-throughput screening for determining 15-lipoxygenase activity.
Journal of biomolecular screening.
2010 Jul; 15(6):671-9. doi:
10.1177/1087057110373383. [PMID: 20581078] - Mohammad Mizanur Rahman, Kazuaki Ninomiya, Chiaki Ogino, Nobuaki Shimizu. Ultrasound-induced membrane lipid peroxidation and cell damage of Escherichia coli in the presence of non-woven TiO2 fabrics.
Ultrasonics sonochemistry.
2010 Apr; 17(4):738-43. doi:
10.1016/j.ultsonch.2009.12.001. [PMID: 20056470] - Monica Mosca, Andrea Ceglie, Luigi Ambrosone. Lipid oxidation in water-in-olive oil emulsions initiated by a lipophilic radical source.
The journal of physical chemistry. B.
2010 Mar; 114(10):3550-8. doi:
10.1021/jp911288e. [PMID: 20175548] - Zhi Hong Wang, Kyoung Ah Kang, Rui Zhang, Mei Jing Piao, Su Hyun Jo, Ju Sun Kim, Sam Sik Kang, Jong Sung Lee, Deok Hoon Park, Jin Won Hyun. Myricetin suppresses oxidative stress-induced cell damage via both direct and indirect antioxidant action.
Environmental toxicology and pharmacology.
2010 Jan; 29(1):12-8. doi:
10.1016/j.etap.2009.08.007. [PMID: 21787576] - Angela Di Pietro, Giuseppa Visalli, Fortunato Munaò, Barbara Baluce, Sebastiano La Maestra, Patrizia Primerano, Francesco Corigliano, Silvio De Flora. Oxidative damage in human epithelial alveolar cells exposed in vitro to oil fly ash transition metals.
International journal of hygiene and environmental health.
2009 Mar; 212(2):196-208. doi:
10.1016/j.ijheh.2008.05.005. [PMID: 18667355] - Hironori Tsuchiya, Takahiro Ueno, Maki Mizogami, Ko Takakura. Antioxidant activity analysis by liposomal membrane system and application to anesthetics.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2008 Dec; 24(12):1557-62. doi:
10.2116/analsci.24.1557. [PMID: 19075464] - Yan Wang, Sheldon I Feinstein, Aron B Fisher. Peroxiredoxin 6 as an antioxidant enzyme: protection of lung alveolar epithelial type II cells from H2O2-induced oxidative stress.
Journal of cellular biochemistry.
2008 Jul; 104(4):1274-85. doi:
10.1002/jcb.21703. [PMID: 18260127] - Chie Ohmura, Hirotaka Watada, Tomoaki Shimizu, Ken Sakai, Hiroshi Uchino, Yoshio Fujitani, Akio Kanazawa, Takahisa Hirose, Ryuzo Kawamori. Calcium channel blocker, azelnidipine, reduces lipid hydroperoxides in patients with type 2 diabetes independent of blood pressure.
Endocrine journal.
2007 Dec; 54(5):805-11. doi:
10.1507/endocrj.k07-063. [PMID: 17895576] - Tsuyoshi Kaneko, Hirofumi Matsui, Osamu Shimokawa, Akira Nakahara, Ichinosuke Hyodo. Cellular membrane fluidity measurement by fluorescence polarization in indomethacin-induced gastric cellular injury in vitro.
Journal of gastroenterology.
2007 Dec; 42(12):939-46. doi:
10.1007/s00535-007-2116-y. [PMID: 18085350] - Yoshichika Kawai, Mariko Miyoshi, Jae-Hak Moon, Junji Terao. Detection of cholesteryl ester hydroperoxide isomers using gas chromatography-mass spectrometry combined with thin-layer chromatography blotting.
Analytical biochemistry.
2007 Jan; 360(1):130-7. doi:
10.1016/j.ab.2006.09.028. [PMID: 17097596] - Vanessa Steenkamp, Heidi Grimmer, Mpho Semano, Mary Gulumian. Antioxidant and genotoxic properties of South African herbal extracts.
Mutation research.
2005 Mar; 581(1-2):35-42. doi:
10.1016/j.mrgentox.2004.10.009. [PMID: 15725603] - Jeong-Ho Sohn, Yusuke Taki, Hideki Ushio, Toshiaki Ohshima. Quantitative determination of total lipid hydroperoxides by a flow injection analysis system.
Lipids.
2005 Feb; 40(2):203-9. doi:
10.1007/s11745-005-1376-2. [PMID: 15884769] - Jostein Dahle, Egil Kvam. Increased level of oxidative stress in genomically unstable cell clones.
Journal of photochemistry and photobiology. B, Biology.
2004 Mar; 74(1):23-8. doi:
10.1016/j.jphotobiol.2004.01.004. [PMID: 15043843] - Teruyuki Usui, Satomi Shizuuchi, Hirohito Watanabe, Fumitaka Hayase. Protective effect of Blue-M1 against oxidative stress on COS-1 cells.
Bioscience, biotechnology, and biochemistry.
2004 Jan; 68(1):247-9. doi:
10.1271/bbb.68.247. [PMID: 14745194] - Yoshiro Saito, Yasukazu Yoshida, Takashi Akazawa, Kazuhiko Takahashi, Etsuo Niki. Cell death caused by selenium deficiency and protective effect of antioxidants.
The Journal of biological chemistry.
2003 Oct; 278(41):39428-34. doi:
10.1074/jbc.m305542200. [PMID: 12888577] - Yuko Okimoto, Eiji Warabi, Youichiro Wada, Etsuto Niki, Tatsuhiko Kodama, Noriko Noguchi. A novel method of following oxidation of low-density lipoprotein using a sensitive fluorescent probe, diphenyl-1-pyrenylphosphine.
Free radical biology & medicine.
2003 Sep; 35(6):576-85. doi:
10.1016/s0891-5849(03)00330-7. [PMID: 12957650] - Joon-Hyuck Yang, Jeen-Woo Park. Oxalomalate, a competitive inhibitor of NADP+-dependent isocitrate dehydrogenase, enhances lipid peroxidation-mediated oxidative damage in U937 cells.
Archives of biochemistry and biophysics.
2003 Aug; 416(1):31-7. doi:
10.1016/s0003-9861(03)00291-1. [PMID: 12859979] - Idit Matot, Yefim Manevich, Abu Bakr Al-Mehdi, Chun Song, Aron B Fisher. Fluorescence imaging of lipid peroxidation in isolated rat lungs during nonhypoxic lung ischemia.
Free radical biology & medicine.
2003 Mar; 34(6):785-90. doi:
10.1016/s0891-5849(02)01435-1. [PMID: 12633755] - Jhang Ho Pak, Yefim Manevich, Han Suk Kim, Sheldon I Feinstein, Aron B Fisher. An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells.
The Journal of biological chemistry.
2002 Dec; 277(51):49927-34. doi:
10.1074/jbc.m204222200. [PMID: 12372839] - J Terao, M Miyoshi, S Miyamoto. Thin-layer chromatography blotting for the fluorescence detection of phospholipid hydroperoxides and cholesteryl ester hydroperoxides.
Journal of chromatography. B, Biomedical sciences and applications.
2001 Dec; 765(2):199-203. doi:
10.1016/s0378-4347(01)00426-1. [PMID: 11767313] - M Takahashi, M Shibata, E Niki. Estimation of lipid peroxidation of live cells using a fluorescent probe, diphenyl-1-pyrenylphosphine.
Free radical biology & medicine.
2001 Jul; 31(2):164-74. doi:
10.1016/s0891-5849(01)00575-5. [PMID: 11440828] - Y Okimotoa, A Watanabea, E Nikia, T Yamashitab, N Noguchia. A novel fluorescent probe diphenyl-1-pyrenylphosphine to follow lipid peroxidation in cell membranes.
FEBS letters.
2000 Jun; 474(2-3):137-40. doi:
10.1016/s0014-5793(00)01587-8. [PMID: 10838073] - T Ohshima, A Hopia, J B German, E N Frankel. Determination of hydroperoxides and structures by high-performance liquid chromatography with post-column detection with diphenyl-1-pyrenylphosphine.
Lipids.
1996 Oct; 31(10):1091-6. doi:
10.1007/bf02522467. [PMID: 8898309] - K Akasaka, H Ohrui, H Meguro. Simultaneous determination of hydroperoxides of phosphatidylcholine, cholesterol esters and triacylglycerols by column-switching high-performance liquid chromatography with a post-column detection system.
Journal of chromatography.
1993 Dec; 622(2):153-9. doi:
10.1016/0378-4347(93)80261-2. [PMID: 8150864] - K Akasaka, S Ijichi, K Watanabe, H Ohrui, H Meguro. High-performance liquid chromatography and post-column derivatization with diphenyl-1-pyrenylphosphine for fluorimetric determination of triacylglycerol hydroperoxides.
Journal of chromatography.
1992 Apr; 596(2):197-202. doi:
10.1016/0021-9673(92)85007-g. [PMID: 1400836] - H Meguro, K Akasaka, H Ohrui. Determination of hydroperoxides with fluorometric reagent diphenyl-1-pyrenylphosphine.
Methods in enzymology.
1990; 186(?):157-61. doi:
10.1016/0076-6879(90)86105-5. [PMID: 2233291]