Diniconazole (BioDeep_00000178379)
human metabolite blood metabolite
代谢物信息卡片
化学式: C15H17Cl2N3O (325.07486120000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)C(O)C(=CC1=C(Cl)C=C(Cl)C=C1)N1C=NC=N1
InChI: InChI=1S/C15H17Cl2N3O/c1-15(2,3)14(21)13(20-9-18-8-19-20)6-10-4-5-11(16)7-12(10)17/h4-9,14,21H,1-3H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Huiping Chen, Yongpan Shan, Lidong Cao, Pengyue Zhao, Chong Cao, Fengmin Li, Qiliang Huang. Enhanced Fungicidal Efficacy by Co-Delivery of Azoxystrobin and Diniconazole with Cauliflower-Like Metal-Organic Frameworks NH2-Al-MIL-101.
International journal of molecular sciences.
2021 Sep; 22(19):. doi:
10.3390/ijms221910412
. [PMID: 34638750] - Tuğçe Kalefetoğlu Macar, Oksal Macar, Emine Yalçιn, Kültiğin Çavuşoğlu. Preventive efficiency of Cornelian cherry (Cornus mas L.) fruit extract in diniconazole fungicide-treated Allium cepa L. roots.
Scientific reports.
2021 01; 11(1):2534. doi:
10.1038/s41598-021-82132-4
. [PMID: 33510323] - Yao Wang, Wentao Zhu, Dezhen Wang, Miaomiao Teng, Jin Yan, Jiyan Miao, Zhiqiang Zhou. 1H NMR-based metabolomics analysis of adult zebrafish (Danio rerio) after exposure to diniconazole as well as its bioaccumulation behavior.
Chemosphere.
2017 Feb; 168(?):1571-1577. doi:
10.1016/j.chemosphere.2016.11.157
. [PMID: 27938984] - Ahmed Mohammed AlJabr, Abid Hussain, Muhammad Rizwan-Ul-Haq, Hassan Al-Ayedh. Toxicity of Plant Secondary Metabolites Modulating Detoxification Genes Expression for Natural Red Palm Weevil Pesticide Development.
Molecules (Basel, Switzerland).
2017 Jan; 22(1):. doi:
10.3390/molecules22010169
. [PMID: 28117698] - Enze Sheng, Haiyan Shi, Liangliang Zhou, Xiude Hua, Lu Feng, Tong Yu, Minghua Wang. Dual-labeled time-resolved fluoroimmunoassay for simultaneous detection of clothianidin and diniconazole in agricultural samples.
Food chemistry.
2016 Feb; 192(?):525-30. doi:
10.1016/j.foodchem.2015.07.023
. [PMID: 26304380] - Chen Liu, Xiao Tian LV, Wen Xue Zhu, Hao Yang QU, Yong Xin Gao, Bao Yuan Guo, Hui Li Wang. Enantioselective bioaccumulation of diniconazole in Tenebrio molitor larvae.
Chirality.
2013 Dec; 25(12):917-22. doi:
10.1002/chir.22234
. [PMID: 24009189] - Jin Hui Chen, Hui Li Wang, Bao Yuan Guo, Peng Xu, Jian Zhong Li. The enantioselective pharmacokinetics metabolism of diniconazole in quail (Coturnix coturnixs japonica).
Chirality.
2013 Dec; 25(12):910-6. doi:
10.1002/chir.22233
. [PMID: 24009183] - Hülya Koç, Burak Uflaz, Yusuf Coskun, Elife Erarslan, Ahmet Bayrak, Ilhami Yüksel. Severe hepatotoxicity and acute renal failure caused by diniconazole.
Clinics and research in hepatology and gastroenterology.
2012 Oct; 36(5):e104-5. doi:
10.1016/j.clinre.2012.03.032
. [PMID: 22579069] - Jeffrey C Suttle, Suzanne R Abrams, Luis De Stefano-Beltrán, Linda L Huckle. Chemical inhibition of potato ABA-8'-hydroxylase activity alters in vitro and in vivo ABA metabolism and endogenous ABA levels but does not affect potato microtuber dormancy duration.
Journal of experimental botany.
2012 Sep; 63(15):5717-25. doi:
10.1093/jxb/ers146
. [PMID: 22664582] - Nenghui Ye, Guohui Zhu, Yinggao Liu, Aying Zhang, Yingxuan Li, Rui Liu, Lu Shi, Liguo Jia, Jianhua Zhang. Ascorbic acid and reactive oxygen species are involved in the inhibition of seed germination by abscisic acid in rice seeds.
Journal of experimental botany.
2012 Mar; 63(5):1809-22. doi:
10.1093/jxb/err336
. [PMID: 22200664] - Yuanbo Li, Fengshou Dong, Xingang Liu, Jun Xu, Jing Li, Zhiqiang Kong, Xiu Chen, Xuyang Liang, Yongquan Zheng. Simultaneous enantioselective determination of triazole fungicides in soil and water by chiral liquid chromatography/tandem mass spectrometry.
Journal of chromatography. A.
2012 Feb; 1224(?):51-60. doi:
10.1016/j.chroma.2011.12.044
. [PMID: 22209355] - Tomoko Toyama, Michiru Tahara, Kisaburo Nagamune, Kenji Arimitsu, Yoshio Hamashima, Nirianne M Q Palacpac, Hiroshi Kawaide, Toshihiro Horii, Kazuyuki Tanabe. Gibberellin biosynthetic inhibitors make human malaria parasite Plasmodium falciparum cells swell and rupture to death.
PloS one.
2012; 7(3):e32246. doi:
10.1371/journal.pone.0032246
. [PMID: 22412858] - Zhenjiang Liu, Yahui Jin, Minghua Wang. Determination of diniconazole in agricultural samples by sol-gel immunoaffinity extraction procedure coupled with HPLC and ELISA.
PloS one.
2012; 7(10):e46929. doi:
10.1371/journal.pone.0046929
. [PMID: 23056532] - Yahui Jin, Minghua Wang. [Preparation of immunoaffinity chromatographic column specific to diniconazole and its applications to the pretreatment of samples].
Se pu = Chinese journal of chromatography.
2012 Jan; 30(1):67-70. doi:
10.3724/sp.j.1123.2011.09036
. [PMID: 22667094] - Guohui Zhu, Yinggao Liu, Nenghui Ye, Rui Liu, Jianhua Zhang. Involvement of the abscisic acid catabolic gene CYP707A2 in the glucose-induced delay in seed germination and post-germination growth of Arabidopsis.
Physiologia plantarum.
2011 Dec; 143(4):375-84. doi:
10.1111/j.1399-3054.2011.01510.x
. [PMID: 21883251] - Yinggao Liu, Nenghui Ye, Rui Liu, Moxian Chen, Jianhua Zhang. H2O2 mediates the regulation of ABA catabolism and GA biosynthesis in Arabidopsis seed dormancy and germination.
Journal of experimental botany.
2010 Jun; 61(11):2979-90. doi:
10.1093/jxb/erq125
. [PMID: 20460363] - Qiuxia Wang, Jing Qiu, Zhiqiang Zhou, Aocheng Cao, Xinquan Wang, Wentao Zhu, Ziheng Dang. Stereoselective pharmacokinetics of diniconazole enantiomers in rabbits.
Chirality.
2009 Jul; 21(7):699-703. doi:
10.1002/chir.20667
. [PMID: 18973222] - Guohui Zhu, Nenghui Ye, Jianhua Zhang. Glucose-induced delay of seed germination in rice is mediated by the suppression of ABA catabolism rather than an enhancement of ABA biosynthesis.
Plant & cell physiology.
2009 Mar; 50(3):644-51. doi:
10.1093/pcp/pcp022
. [PMID: 19208695] - Danica E Goggin, Kathryn J Steadman, R J Neil Emery, Scott C Farrow, Roberto L Benech-Arnold, Stephen B Powles. ABA inhibits germination but not dormancy release in mature imbibed seeds of Lolium rigidum Gaud.
Journal of experimental botany.
2009; 60(12):3387-96. doi:
10.1093/jxb/erp175
. [PMID: 19487389] - Mohamed M Amer, Mostafa A Shehata, Hayam M Lotfy, Hany H Monir. Determination of tetraconazole and diniconazole fungicide residues in tomatoes and green beans by capillary gas chromatography.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2007 Jun; 127(6):993-9. doi:
10.1248/yakushi.127.993
. [PMID: 17541250] - Makiko Sugiura, Atsuomi Kimura, Hideaki Fujiwara. Discrimination of enantiomers by means of NMR spectroscopy using chiral liquid crystalline solution: application to triazole fungicides, uniconazole and diniconazole.
Magnetic resonance in chemistry : MRC.
2006 Feb; 44(2):121-6. doi:
10.1002/mrc.1731
. [PMID: 16358291] - Nobutaka Kitahata, Shigeki Saito, Yutaka Miyazawa, Taishi Umezawa, Yukihisa Shimada, Yong Ki Min, Masaharu Mizutani, Nobuhiro Hirai, Kazuo Shinozaki, Shigeo Yoshida, Tadao Asami. Chemical regulation of abscisic acid catabolism in plants by cytochrome P450 inhibitors.
Bioorganic & medicinal chemistry.
2005 Jul; 13(14):4491-8. doi:
10.1016/j.bmc.2005.04.036
. [PMID: 15882944] - R Furuta, T Doi. Chiral separation of diniconazole, uniconazole and structurally related compounds by cyclodextrin-modified micellar electrokinetic chromatography.
Electrophoresis.
1994 Oct; 15(10):1322-5. doi:
10.1002/elps.11501501201
. [PMID: 7895726] - S Hosokawa, J Nakamura, S Ito, M Murakami, M Ineyama, K Yoshioka, T Yamada, T Seki, M Matsuo, H Yamada. Hormonal disregulation mechanism in the rat thyroid tumor induced by diniconazole.
The Journal of toxicological sciences.
1993 Feb; 18(1):57-67. doi:
10.2131/jts.18.57
. [PMID: 8474151]