5,5-Dimethyl-1,3-cyclohexanedione (BioDeep_00000178342)
human metabolite blood metabolite
代谢物信息卡片
5,5-Dimethylcyclohexane-1,3-dione
化学式: C8H12O2 (140.0837252)
中文名称: 双甲酮
谱图信息:
最多检出来源 Homo sapiens(blood) 80%
分子结构信息
SMILES: CC1(C)CC(=O)CC(=O)C1
InChI: InChI=1S/C8H12O2/c1-8(2)4-6(9)3-7(10)5-8/h3-5H2,1-2H3
描述信息
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Joshua A Baccile, Joseph E Spraker, Henry H Le, Eileen Brandenburger, Christian Gomez, Jin Woo Bok, Juliane Macheleidt, Axel A Brakhage, Dirk Hoffmeister, Nancy P Keller, Frank C Schroeder. Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus.
Nature chemical biology.
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Journal of molecular biology.
2012 Aug; 421(4-5):662-70. doi:
10.1016/j.jmb.2012.01.047. [PMID: 22321799] - Rebecca N Burns, Nader H Moniri. Agonist- and hydrogen peroxide-mediated oxidation of the β2 adrenergic receptor: evidence of receptor s-sulfenation as detected by a modified biotin-switch assay.
The Journal of pharmacology and experimental therapeutics.
2011 Dec; 339(3):914-21. doi:
10.1124/jpet.111.185975. [PMID: 21917560] - Alinanuswe S Mwakaboko, Binne Zwanenburg. Single step synthesis of strigolactone analogues from cyclic keto enols, germination stimulants for seeds of parasitic weeds.
Bioorganic & medicinal chemistry.
2011 Aug; 19(16):5006-11. doi:
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Journal of natural products.
2011 Apr; 74(4):757-63. doi:
10.1021/np100837r. [PMID: 21341764] - Ming J Wu, Patrick J O'Doherty, Patricia A Murphy, Victoria Lyons, Melinda Christophersen, Peter J Rogers, Trevor D Bailey, Vincent J Higgins. Different reactive oxygen species lead to distinct changes of cellular metal ions in the eukaryotic model organism Saccharomyces cerevisiae.
International journal of molecular sciences.
2011; 12(11):8119-32. doi:
10.3390/ijms12118119. [PMID: 22174654] - Ming J Wu, Frank M Clarke, Peter J Rogers, Paul Young, Narelle Sales, Patrick J O'Doherty, Vincent J Higgins. Identification of a protein with antioxidant activity that is important for the protection against beer ageing.
International journal of molecular sciences.
2011; 12(9):6089-103. doi:
10.3390/ijms12096089. [PMID: 22016646] - Douglas S Rehder, Chad R Borges. Possibilities and pitfalls in quantifying the extent of cysteine sulfenic acid modification of specific proteins within complex biofluids.
BMC biochemistry.
2010 Jul; 11(?):25. doi:
10.1186/1471-2091-11-25. [PMID: 20594348] - Kai Xiao, Ke Shen, Jian-Feng Zhong, Guo-Qing Li. Effects of dietary sodium on performance, flight and compensation strategies in the cotton bollworm, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae).
Frontiers in zoology.
2010 Apr; 7(?):11. doi:
10.1186/1742-9994-7-11. [PMID: 20385025] - Beatriz Alvarez, Sebastián Carballal, Lucía Turell, Rafael Radi. Formation and reactions of sulfenic acid in human serum albumin.
Methods in enzymology.
2010; 473(?):117-36. doi:
10.1016/s0076-6879(10)73005-6. [PMID: 20513474] - Kimberly J Nelson, Chananat Klomsiri, Simona G Codreanu, Laura Soito, Daniel C Liebler, Leann C Rogers, Larry W Daniel, Leslie B Poole. Use of dimedone-based chemical probes for sulfenic acid detection methods to visualize and identify labeled proteins.
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10.1016/s0076-6879(10)73004-4. [PMID: 20513473] - S N Lavergne, H Wang, H E Callan, B K Park, D J Naisbitt. "Danger" conditions increase sulfamethoxazole-protein adduct formation in human antigen-presenting cells.
The Journal of pharmacology and experimental therapeutics.
2009 Nov; 331(2):372-81. doi:
10.1124/jpet.109.155374. [PMID: 19666748] - György Kátay, Péter G Ott, Edit Kátay, Donát Magyar, Erno Tyihák. Potential role of formaldehyde in the mechanism of action of ascorbigens on the basis of BioArena studies.
Biomedical chromatography : BMC.
2009 Apr; 23(4):412-8. doi:
10.1002/bmc.1133. [PMID: 19039806] - Ernest Adeghate, Péter Sótonyi, Huba Kalász. Chronic experimental diabetes accelerates urinary elimination of deprenyl and its metabolites.
The open medicinal chemistry journal.
2008 Jan; 2(?):1-5. doi:
10.2174/1874104500802010001. [PMID: 19662137] - Lucía Turell, Horacio Botti, Sebastián Carballal, Gerardo Ferrer-Sueta, José M Souza, Rosario Durán, Bruce A Freeman, Rafael Radi, Beatriz Alvarez. Reactivity of sulfenic acid in human serum albumin.
Biochemistry.
2008 Jan; 47(1):358-67. doi:
10.1021/bi701520y. [PMID: 18078330] - Karin Kaiserova, Sanjay Srivastava, Joseph D Hoetker, Sunday O Awe, Xian-Liang Tang, Jian Cai, Aruni Bhatnagar. Redox activation of aldose reductase in the ischemic heart.
The Journal of biological chemistry.
2006 Jun; 281(22):15110-20. doi:
10.1074/jbc.m600837200. [PMID: 16567803] - Veit Roessner, Henrik Uebel, Andreas Becker, Georg Beck, Stefan Bleich, Aribert Rothenberger. Serum level of semicarbazide-sensitive amine oxidase in children with ADHD.
Behavioral and brain functions : BBF.
2006 Jan; 2(?):5. doi:
10.1186/1744-9081-2-5. [PMID: 16441883] - Limei Tao, Ann M English. Protein S-glutathiolation triggered by decomposed S-nitrosoglutathione.
Biochemistry.
2004 Apr; 43(13):4028-38. doi:
10.1021/bi035924o. [PMID: 15049710] - Sebastián Carballal, Rafael Radi, Marion C Kirk, Stephen Barnes, Bruce A Freeman, Beatriz Alvarez. Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite.
Biochemistry.
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