Dihydro-dids (BioDeep_00000178284)
human metabolite blood metabolite
代谢物信息卡片
化学式: C16H12N2O6S4 (455.9578212)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 92.31%
分子结构信息
SMILES: C1=CC(=C(C=C1N=C=S)S(=O)(=O)O)CCC2=C(C=C(C=C2)N=C=S)S(=O)(=O)O
InChI: InChI=1S/C16H12N2O6S4/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24/h3-8H,1-2H2,(H,19,20,21)(H,22,23,24)
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D000345 - Affinity Labels
同义名列表
9 个代谢物同义名
5-isothiocyanato-2-[2-(4-isothiocyanato-2-sulfophenyl)ethyl]benzene-1-sulfonic acid; 5-isothiocyanato-2-[2-(4-isothiocyanato-2-sulfophenyl)ethyl]benzenesulfonic acid; Dihydro-4,4-diisothiocyanostilbene-2,2-disulfonic acid; 4,4-Diisothiocyano-2,2-dihydrostilbene disulfonic acid; 4,4-Diisothiocyano-1,2-diphenylethane-2,2-disulfonate; Dihydro-dids; DihydroDIDS; H(2)DIDS; H2dIDS
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Makoto Kurano, Masako Nishikawa, Hiroyuki Kuma, Masahiro Jona, Yutaka Yatomi. Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes.
PloS one.
2017; 12(5):e0177543. doi:
10.1371/journal.pone.0177543. [PMID: 28494002] - A K Stewart, A Yamamoto, M Nakakuki, T Kondo, S L Alper, H Ishiguro. Functional coupling of apical Cl-/HCO3- exchange with CFTR in stimulated HCO3- secretion by guinea pig interlobular pancreatic duct.
American journal of physiology. Gastrointestinal and liver physiology.
2009 Jun; 296(6):G1307-17. doi:
10.1152/ajpgi.90697.2008. [PMID: 19342507] - Norma Marchesini, Roberto Docampo. A plasma membrane P-type H(+)-ATPase regulates intracellular pH in Leishmania mexicana amazonensis.
Molecular and biochemical parasitology.
2002 Feb; 119(2):225-36. doi:
10.1016/s0166-6851(01)00419-4. [PMID: 11814574] - N Van Der Heyden, R Docampo. Intracellular pH in mammalian stages of Trypanosoma cruzi is K+-dependent and regulated by H+-ATPases.
Molecular and biochemical parasitology.
2000 Feb; 105(2):237-51. doi:
10.1016/s0166-6851(99)00184-x. [PMID: 10693746] - J R Hirsch, T Gonska, S Waldegger, F Lang, E Schlatter. Na(+)-dependent and -independent amino acid transport systems in immortalized human kidney epithelial cells derived from the proximal tubule.
Kidney & blood pressure research.
1998; 21(1):50-8. doi:
10.1159/000025843. [PMID: 9661137] - C Fraser-L'Hostis, F Defrise-Quertain, D Coral, J Deshusses. Regulation of the intracellular pH in the protozoan parasite Trypanosoma brucei brucei.
Biological chemistry.
1997 Sep; 378(9):1039-46. doi:
10.1515/bchm.1997.378.9.1039. [PMID: 9348114] - W E Dale, J A Textor, R W Mercer, L Simchowitz. Expression and characterization of the human erythrocyte anion exchanger in a baculovirus/Sf-9 cell system.
Protein expression and purification.
1996 Feb; 7(1):1-11. doi:
10.1006/prep.1996.0001. [PMID: 9172773] - L Vieira, Z I Cabantchik. Bicarbonate ions and pH regulation of Leishmania major promastigotes.
FEBS letters.
1995 Mar; 361(1):123-6. doi:
10.1016/0014-5793(95)00171-5. [PMID: 7890030] - L Vieira, I Slotki, Z I Cabantchik. Chloride conductive pathways which support electrogenic H+ pumping by Leishmania major promastigotes.
The Journal of biological chemistry.
1995 Mar; 270(10):5299-304. doi:
10.1074/jbc.270.10.5299. [PMID: 7890641] - A M Azzarolo, G Ritchie, G Quamme. Inhibition of sodium-phosphate cotransport in renal brush-border membranes with the stilbenedisulfonate, H2-DIDS.
Biochimica et biophysica acta.
1991 Oct; 1069(1):70-6. doi:
10.1016/0005-2736(91)90105-h. [PMID: 1932052] - D Kietz, D Bartel, S Lepke, H Passow. pH-dependence of inhibition by H2DIDS of mouse erythroid band 3-mediated Cl- transport in Xenopus oocytes. The effect of oligonucleotide-directed replacement of Lys-558 by an Asn residue.
Biochimica et biophysica acta.
1991 Apr; 1064(1):81-8. doi:
10.1016/0005-2736(91)90414-4. [PMID: 1902748] - A Felipe, S K Moule, J D McGivan. Bicarbonate stimulation of Na+ transport in liver basolateral plasma membrane vesicles requires the presence of a transmembrane pH gradient.
Biochimica et biophysica acta.
1990 Nov; 1029(1):61-6. doi:
10.1016/0005-2736(90)90436-r. [PMID: 2171655] - S Muallem, P A Loessberg. Intracellular pH-regulatory mechanisms in pancreatic acinar cells. II. Regulation of H+ and HCO3- transporters by Ca2(+)-mobilizing agonists.
The Journal of biological chemistry.
1990 Aug; 265(22):12813-9. doi:
NULL. [PMID: 2165486] - B L Tufts, R G Boutilier. CO2 transport properties of the blood of a primitive vertebrate, Myxine glutinosa (L.).
Experimental biology.
1990; 48(6):341-7. doi:
NULL. [PMID: 2114305] - D Bartel, S Lepke, G Layh-Schmitt, B Legrum, H Passow. Anion transport in oocytes of Xenopus laevis induced by expression of mouse erythroid band 3 protein--encoding cRNA and of a cRNA derivative obtained by site-directed mutagenesis at the stilbene disulfonate binding site.
The EMBO journal.
1989 Dec; 8(12):3601-9. doi:
10.1002/j.1460-2075.1989.tb08533.x. [PMID: 2479548] - A Janoshazi, J L Seifter, A K Solomon. Interactions between anion exchange and other membrane proteins in rabbit kidney medullary collecting duct cells.
The Journal of membrane biology.
1989 Nov; 112(1):39-49. doi:
10.1007/bf01871162. [PMID: 2593138] - C H Pedemonte, J H Kaplan. Inhibition and derivatization of the renal Na,K-ATPase by dihydro-4,4'-diisothiocyanatostilbene-2,2'-disulfonate.
Biochemistry.
1988 Oct; 27(20):7966-73. doi:
10.1021/bi00420a056. [PMID: 2849997] - A A Altamirano, S L Hamilton, J M Russell. A plasma membrane-enriched preparation from giant barnacle muscle fibers.
Analytical biochemistry.
1988 Jul; 172(1):203-9. doi:
10.1016/0003-2697(88)90433-2. [PMID: 2973259] - S W Pimplikar, R A Reithmeier. Identification, purification, and characterization of a stilbenedisulfonate binding glycoprotein from canine kidney brush border membranes. A candidate for a renal anion exchanger.
The Journal of biological chemistry.
1988 Mar; 263(9):4485-93. doi:
10.1016/s0021-9258(18)68952-5. [PMID: 3346257] - K Ziegler. Evidence for glycoprotein components of the hepatocellular bile acid transporter.
Biochimica et biophysica acta.
1987 Oct; 903(3):510-8. doi:
10.1016/0005-2736(87)90058-7. [PMID: 3663657] - L S Gray, J H Russell. Cytolytic T lymphocyte effector function requires plasma membrane chloride flux.
Journal of immunology (Baltimore, Md. : 1950).
1986 Apr; 136(8):3032-7. doi:
NULL. [PMID: 3485679] - M Täfler, K Ziegler, M Frimmer. Iodipamide uptake by rat liver plasma membrane vesicles enriched in the sinusoidal fraction: evidence for a carrier-mediated transport dependent on membrane potential.
Biochimica et biophysica acta.
1986 Feb; 855(1):157-68. doi:
10.1016/0005-2736(86)90200-2. [PMID: 3942739] - L Hsu, M Morrison. A new variant of the anion transport protein in human erythrocytes.
Biochemistry.
1985 Jun; 24(13):3086-90. doi:
10.1021/bi00334a003. [PMID: 4027230] - M J Spiro, R G Spiro. Effect of anion-specific inhibitors on the utilization of sugar nucleotides for N-linked carbohydrate unit assembly by thyroid endoplasmic reticulum vesicles.
The Journal of biological chemistry.
1985 May; 260(9):5808-15. doi:
. [PMID: 2580839] - S Kitagawa, J Endo, R Kubo, F Kametani. Inhibitory effects of 4,4'-diisothiocyanostilbene-2,2'-disulfonate (DIDS) on the ADP-stimulated aggregation of gel-filtered bovine blood platelets.
Biochemical and biophysical research communications.
1983 Feb; 111(1):306-11. doi:
10.1016/s0006-291x(83)80152-1. [PMID: 6830595] - F J Koschier, M F Stokols, J M Goldinger, M Acara, S K Hong. Effect of DIDS on renal tubular transport.
The American journal of physiology.
1980 Feb; 238(2):F99-106. doi:
10.1152/ajprenal.1980.238.2.f99. [PMID: 7361895]