Difluoromethane (BioDeep_00000178267)

   

human metabolite blood metabolite


代谢物信息卡片


Methylene difluoride

化学式: CH2F2 (52.0125)
中文名称: 二氟甲烷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(F)F
InChI: InChI=1S/CH2F2/c2-1-3/h1H2

描述信息

同义名列表

8 个代谢物同义名

Methylene difluoride; Methylene fluoride; DIFLUOROMETHANE; Difluormethan; Freon 32; CH2F2; HFC32; CF2H2



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Reimar Spohr, Gunjana Sharma, Pontus Forsberg, Mikael Karlsson, Anders Hallén, Lars Westerberg. Stroke asymmetry of tilted superhydrophobic ion track textures. Langmuir : the ACS journal of surfaces and colloids. 2010 May; 26(9):6790-6. doi: 10.1021/la904137t. [PMID: 20085343]
  • Arijit Das, Hyojin Ko, Lauren E Burianek, Matthew O Barrett, T Kendall Harden, Kenneth A Jacobson. Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. Journal of medicinal chemistry. 2010 Jan; 53(1):471-80. doi: 10.1021/jm901432g. [PMID: 19902968]
  • Stefan Balaz. Modeling kinetics of subcellular disposition of chemicals. Chemical reviews. 2009 May; 109(5):1793-899. doi: 10.1021/cr030440j. [PMID: 19265398]
  • Maria Kolympadi, Marco Fontanella, Chiara Venturi, Sabine André, Hans-Joachim Gabius, Jesús Jiménez-Barbero, Pierre Vogel. Synthesis and conformational analysis of (alpha-D-galactosyl)phenylmethane and alpha-,beta-difluoromethane analogues: interactions with the plant lectin viscumin. Chemistry (Weinheim an der Bergstrasse, Germany). 2009; 15(12):2861-73. doi: 10.1002/chem.200801394. [PMID: 19185038]
  • Qiongfen Qiu, Matthias Noll, Wolf-Rainer Abraham, Yahai Lu, Ralf Conrad. Applying stable isotope probing of phospholipid fatty acids and rRNA in a Chinese rice field to study activity and composition of the methanotrophic bacterial communities in situ. The ISME journal. 2008 Jun; 2(6):602-14. doi: 10.1038/ismej.2008.34. [PMID: 18385771]
  • Minita Shrestha, Wolf-Rainer Abraham, Pravin Malla Shrestha, Matthias Noll, Ralf Conrad. Activity and composition of methanotrophic bacterial communities in planted rice soil studied by flux measurements, analyses of pmoA gene and stable isotope probing of phospholipid fatty acids. Environmental microbiology. 2008 Feb; 10(2):400-12. doi: 10.1111/j.1462-2920.2007.01462.x. [PMID: 18177369]
  • Akira Sakata, Takashi Ochiai, Hiroshi Shimeno, Sadao Hikishima, Tsutomu Yokomatsu, Shiroshi Shibuya, Akihisa Toda, Reiko Eyanagi, Shinji Soeda. Acid sphingomyelinase inhibition suppresses lipopolysaccharide-mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium-induced colitis in mice. Immunology. 2007 Sep; 122(1):54-64. doi: 10.1111/j.1365-2567.2007.02612.x. [PMID: 17451462]
  • Gary H Posner, Byung Chul Suh, Kimberly S Petersen, Patrick Dolan, Elin S Agoston, Thomas W Kensler, John T Koh, Sara Peleg. Difluoromethyl analogs of the natural hormone 1alpha,25-dihydroxyvitamin D3: Design, synthesis, and preliminary biological evaluation. The Journal of steroid biochemistry and molecular biology. 2007 Mar; 103(3-5):213-21. doi: 10.1016/j.jsbmb.2006.12.024. [PMID: 17218093]
  • Akira Sakata, Kazuya Yasuda, Takashi Ochiai, Hiroshi Shimeno, Sadao Hikishima, Tsutomu Yokomatsu, Shiroshi Shibuya, Shinji Soeda. Inhibition of lipopolysaccharide-induced release of interleukin-8 from intestinal epithelial cells by SMA, a novel inhibitor of sphingomyelinase and its therapeutic effect on dextran sulphate sodium-induced colitis in mice. Cellular immunology. 2007 Jan; 245(1):24-31. doi: 10.1016/j.cellimm.2007.03.005. [PMID: 17466962]
  • G D Prestwich, Y Xu, L Qian, J Gajewiak, G Jiang. New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors. Biochemical Society transactions. 2005 Dec; 33(Pt 6):1357-61. doi: 10.1042/bst0331357. [PMID: 16246118]
  • Shinji Soeda, Yoshiaki Tsuji, Takashi Ochiai, Ken-ichi Mishima, Katsunori Iwasaki, Michihiro Fujiwara, Tsutomu Yokomatsu, Tetsuo Murano, Shiroshi Shibuya, Hiroshi Shimeno. Inhibition of sphingomyelinase activity helps to prevent neuron death caused by ischemic stress. Neurochemistry international. 2004 Oct; 45(5):619-26. doi: 10.1016/j.neuint.2004.04.001. [PMID: 15234103]
  • Yoshiaki Tsuji, Shinji Soeda, Takashi Ochiai, Ken-ichi Mishima, Katsunori Iwasaki, Michihiro Fujiwara, Tsutomu Yokomatsu, Tetsuo Murano, Takesi Akiyama, Shiroshi Shibuya, Hiroshi Shimeno. [Synthesis of sphingomyelin analogues as a sphingomyelinase inhibitor and the application as a blocking agent of extracellular stress signaling]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2002 Nov; 120(1):67P-69P. doi: NULL. [PMID: 12491783]
  • M K Ellis, J L Naylor, M A Collins, T Green. Metabolism and disposition of difluoromethane (HFC32) in the mouse. Human & experimental toxicology. 1996 Jul; 15(7):592-6. doi: 10.1177/096032719601500707. [PMID: 8818713]