Di-tert-butyl ether (BioDeep_00000178155)

   

human metabolite blood metabolite


代谢物信息卡片


2-(tert-butoxy)-2-methylpropane

化学式: C8H18O (130.1357578)
中文名称: 叔丁醚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C)OC(C)(C)C
InChI: InChI=1S/C8H18O/c1-7(2,3)9-8(4,5)6/h1-6H3

描述信息

同义名列表

2 个代谢物同义名

2-(tert-butoxy)-2-methylpropane; Di-Tert-Butyl Ether



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Françoise Fayolle-Guichard, Jonathan Durand, Mathilde Cheucle, Mònica Rosell, Rory Julien Michelland, Jean-Philippe Tracol, Françoise Le Roux, Geneviève Grundman, Olivier Atteia, Hans H Richnow, Alain Dumestre, Yves Benoit. Study of an aquifer contaminated by ethyl tert-butyl ether (ETBE): site characterization and on-site bioremediation. Journal of hazardous materials. 2012 Jan; 201-202(?):236-43. doi: 10.1016/j.jhazmat.2011.11.074. [PMID: 22177017]
  • Laura Campo, Andrea Cattaneo, Dario Consonni, Licia Scibetta, Paolo Costamagna, Domenico M Cavallo, Pier Alberto Bertazzi, Silvia Fustinoni. Urinary methyl tert-butyl ether and benzene as biomarkers of exposure to urban traffic. Environment international. 2011 Feb; 37(2):404-11. doi: 10.1016/j.envint.2010.11.002. [PMID: 21131048]
  • L Dong-mei, G Yi, Y Chun-Tao, H Yu-feng, H Xiao-dong. Effects of subchronic methyl tert-butyl ether ether exposure on male Sprague-Dawley rats. Toxicology and industrial health. 2009 Feb; 25(1):15-23. doi: 10.1177/0748233708101594. [PMID: 19318501]
  • Xiaopeng Shi, Yin Wu, Taijun Hang, Xiaofeng Xu, Likun Ding, Yun Tian, Aidong Wen. Application of a sensitive liquid chromatographic/tandem mass spectrometric method to a pharmacokinetic study of allylestrenol in healthy Chinese female volunteers. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2008 Aug; 871(1):90-4. doi: 10.1016/j.jchromb.2008.06.054. [PMID: 18639502]
  • Dongmei Li, Chuntao Yuan, Yi Gong, Yufeng Huang, Xiaodong Han. The effects of methyl tert-butyl ether (MTBE) on the male rat reproductive system. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008 Jul; 46(7):2402-8. doi: 10.1016/j.fct.2008.03.024. [PMID: 18467015]
  • Y Yuan, H F Wang, H F Sun, H F Du, L H Xu, Y F Liu, X F Ding, D P Fu, K X Liu. Adduction of DNA with MTBE and TBA in mice studied by accelerator mass spectrometry. Environmental toxicology. 2007 Dec; 22(6):630-5. doi: 10.1002/tox.20295. [PMID: 18000852]
  • Adriana M Doi, Georgette Hill, John Seely, James R Hailey, Grace Kissling, John R Bucher. alpha 2u-globulin nephropathy and renal tumors in national toxicology program studies. Toxicologic pathology. 2007 Jun; 35(4):533-40. doi: 10.1080/01926230701338941. [PMID: 17562486]
  • Licia Scibetta, Laura Campo, Rosa Mercadante, Vito Foà, Silvia Fustinoni. Determination of low level methyl tert-butyl ether, ethyl tert-butyl ether and methyl tert-amyl ether in human urine by HS-SPME gas chromatography/mass spectrometry. Analytica chimica acta. 2007 Jan; 581(1):53-62. doi: 10.1016/j.aca.2006.07.083. [PMID: 17386425]
  • Dongmei Li, Daqiang Yin, Xiaodong Han. Methyl tert-butyl ether (MTBE)-induced cytotoxicity and oxidative stress in isolated rat spermatogenic cells. Journal of applied toxicology : JAT. 2007 Jan; 27(1):10-7. doi: 10.1002/jat.1178. [PMID: 17177168]
  • Xiao-Zhang Yu, Ji-Dong Gu. Uptake, metabolism, and toxicity of methyl tert-butyl ether (MTBE) in weeping willows. Journal of hazardous materials. 2006 Oct; 137(3):1417-23. doi: 10.1016/j.jhazmat.2006.04.024. [PMID: 16723185]
  • H F Du, L H Xu, H F Wang, Y F Liu, X Y Tang, K X Liu, S X Peng. Formation of MTBE-DNA adducts in mice measured with accelerator mass spectrometry. Environmental toxicology. 2005 Aug; 20(4):397-401. doi: 10.1002/tox.20124. [PMID: 16007660]
  • L Scibetta, S Fustinoni, L Campo, C Valla, P Costamagna, D Consonni, V Foà. [Urinary MTBE as biological marker of exposure to traffic exhaust fumes]. Giornale italiano di medicina del lavoro ed ergonomia. 2005 Jul; 27(3):315-7. doi: NULL. [PMID: 16240583]
  • Adriana M Doi, Joseph H Roycroft, Ronald A Herbert, Joseph K Haseman, James R Hailey, Billy J Chou, Jeffrey A Dill, Sondra L Grumbein, Rodney A Miller, Roger A Renne, John R Bucher. Inhalation toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether in rats and mice. Toxicology. 2004 Jun; 199(1):1-22. doi: 10.1016/j.tox.2003.12.020. [PMID: 15125995]
  • Jeffrey Dill, Alfred Fuciarelli, Kyeonghee Lee, Kathleen Mellinger, Leo Burka, Joseph Roycroft. Toxicokinetics of propylene glycol mono-t-butyl ether following intravenous or inhalation exposure in rats and mice. Inhalation toxicology. 2004 May; 16(5):271-90. doi: 10.1080/08958370490428319. [PMID: 15371180]
  • NULL. NTP technical report on the toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether (CAS No. 57018-52-7) in F344/N rats and B6C3F1 mice and a toxicology study of propylene glycol mono-t-butyl ether in male NBR rats (inhalation studies). National Toxicology Program technical report series. 2004 Mar; ?(515):1-306. doi: NULL. [PMID: 15146215]
  • L Perbellini, F Pasini, P Prigioni, A Rosina. [Occupational exposure to methyl tert-butyl ether (MTBE) at an oil refinery]. Giornale italiano di medicina del lavoro ed ergonomia. 2003 Jul; 25 Suppl(3):39-40. doi: NULL. [PMID: 14979074]
  • A C Licata, W Dekant, C E Smith, S J Borghoff. A physiologically based pharmacokinetic model for methyl tert-butyl ether in humans: implementing sensitivity and variability analyses. Toxicological sciences : an official journal of the Society of Toxicology. 2001 Aug; 62(2):191-204. doi: 10.1093/toxsci/62.2.191. [PMID: 11452131]
  • A Amberg, E Rosner, W Dekant. Toxicokinetics of methyl tert-butyl ether and its metabolites in humans after oral exposure. Toxicological sciences : an official journal of the Society of Toxicology. 2001 May; 61(1):62-7. doi: 10.1093/toxsci/61.1.62. [PMID: 11294975]