Dansylsarcosine (BioDeep_00000177951)

   

human metabolite blood metabolite


代谢物信息卡片


2-[N-Methyl5-(dimethylamino)naphthalene-1-sulphonamido]acetic acid

化学式: C15H18N2O4S (322.0987228)
中文名称: 丹酰肌氨酸哌啶盐
谱图信息: 最多检出来源 Homo sapiens(blood) 97.5%

分子结构信息

SMILES: CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)N(C)CC(=O)O
InChI: InChI=1S/C15H18N2O4S/c1-16(2)13-8-4-7-12-11(13)6-5-9-14(12)22(20,21)17(3)10-15(18)19/h4-9H,10H2,1-3H3,(H,18,19)



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Fabio Polticelli, Loris Leboffe, Valentina Tortosa, Viviana Trezza, Gabriella Fanali, Mauro Fasano, Paolo Ascenzi. Cantharidin inhibits competitively heme-Fe(III) binding to the FA1 site of human serum albumin. Journal of molecular recognition : JMR. 2017 11; 30(11):. doi: 10.1002/jmr.2641. [PMID: 28608578]
  • Kazuaki Taguchi, Victor Tuan Giam Chuang, Keishi Yamasaki, Yukino Urata, Ryota Tanaka, Makoto Anraku, Hakaru Seo, Keiichi Kawai, Toru Maruyama, Teruyuki Komatsu, Masaki Otagiri. Cross-linked human serum albumin dimer has the potential for use as a plasma-retaining agent for the fatty acid-conjugated antidiabetic drugs. The Journal of pharmacy and pharmacology. 2015 Feb; 67(2):255-63. doi: 10.1111/jphp.12338. [PMID: 25556343]
  • Bettina Leber, Vanessa Stadlbauer, Philipp Stiegler, Stefanie Stanzer, Ursula Mayrhauser, Sonja Koestenbauer, Barbara Leopold, Michael Sereinigg, Andreas Puntschart, Tatjana Stojakovic, Karl-Heinz Tscheliessnigg, Karl Oettl. Effect of oxidative stress and endotoxin on human serum albumin in brain-dead organ donors. Translational research : the journal of laboratory and clinical medicine. 2012 Jun; 159(6):487-96. doi: 10.1016/j.trsl.2011.12.005. [PMID: 22633100]
  • Ejaz Ahmad, Gulam Rabbani, Nida Zaidi, Basir Ahmad, Rizwan Hasan Khan. Pollutant-induced modulation in conformation and β-lactamase activity of human serum albumin. PloS one. 2012; 7(6):e38372. doi: 10.1371/journal.pone.0038372. [PMID: 22685563]
  • Gregory T Lautenslager, Clyde W Shearman, Elizabeth Hud, Margo P Cohen. Effects of nonenzymatic glycation and fatty acids on functional properties of human albumin. Metabolism: clinical and experimental. 2011 Dec; 60(12):1683-91. doi: 10.1016/j.metabol.2011.03.022. [PMID: 21632076]
  • Muhammad Kamran Khan, Njara Rakotomanomana, Claire Dufour, Olivier Dangles. Binding of citrus flavanones and their glucuronides and chalcones to human serum albumin. Food & function. 2011 Oct; 2(10):617-26. doi: 10.1039/c1fo10077g. [PMID: 21952533]
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  • Stefan Balaz. Modeling kinetics of subcellular disposition of chemicals. Chemical reviews. 2009 May; 109(5):1793-899. doi: 10.1021/cr030440j. [PMID: 19265398]
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  • Atli Thorarensen, Ronald W Sarver, Fang Tian, Andrea Ho, Donna L Romero, Keith R Marotti. Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor. Bioorganic & medicinal chemistry letters. 2007 Aug; 17(16):4646-9. doi: 10.1016/j.bmcl.2007.05.077. [PMID: 17560104]
  • M Meser Ali, Mark Woods, Eul Hyun Suh, Zoltan Kovacs, Gyula Tircsó, Piyu Zhao, Vikram D Kodibagkar, A Dean Sherry. Albumin-binding PARACEST agents. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2007 Aug; 12(6):855-65. doi: 10.1007/s00775-007-0240-z. [PMID: 17534672]
  • Ulf Mathias, Manfred Jung. Determination of drug-serum protein interactions via fluorescence polarization measurements. Analytical and bioanalytical chemistry. 2007 Jul; 388(5-6):1147-56. doi: 10.1007/s00216-007-1351-7. [PMID: 17554529]
  • Sebastian Klammt, Steffen Mitzner, Jan Stange, Beate Brinkmann, Bernd Drewelow, Jörg Emmrich, Stefan Liebe, Reinhard Schmidt. Albumin-binding function is reduced in patients with decompensated cirrhosis and correlates inversely with severity of liver disease assessed by model for end-stage liver disease. European journal of gastroenterology & hepatology. 2007 Mar; 19(3):257-63. doi: 10.1097/meg.0b013e3280101f7d. [PMID: 17301654]
  • Ming-Hung Ou, Chien-Hung Tu, Su-Ching Tsai, Wei-Thung Lee, Gin-Chung Liu, Yun-Ming Wang. Synthesis and physicochemical characterization of two gadolinium(III) TTDA-like complexes and their interaction with human serum albumin. Inorganic chemistry. 2006 Jan; 45(1):244-54. doi: 10.1021/ic050329r. [PMID: 16390062]
  • Neelam Seedher, Sonu Bhatia. Interaction of non-steroidal anti-inflammatory drugs, etoricoxib and parecoxib sodium, with human serum albumin studied by fluorescence spectroscopy. Drug metabolism and drug interactions. 2006; 22(1):25-45. doi: 10.1515/dmdi.2006.22.1.25. [PMID: 17152346]
  • Jimmy Flarakos, Kenneth L Morand, Paul Vouros. High-throughput solution-based medicinal library screening against human serum albumin. Analytical chemistry. 2005 Mar; 77(5):1345-53. doi: 10.1021/ac048685z. [PMID: 15732917]
  • Keishi Yamasaki, Noriyuki Kuga, Norito Takamura, Yumiko Furuya, Muneaki Hidaka, Tomomi Iwakiri, Ryuuichi Nishii, Manabu Okumura, Hirofumi Kodama, Keiichi Kawai, Kazuhiko Arimori. Inhibitory effects of amino-acid fluids on drug binding to site II of human serum albumin in vitro. Biological & pharmaceutical bulletin. 2005 Mar; 28(3):549-52. doi: 10.1248/bpb.28.549. [PMID: 15744089]
  • Wenying Zhong, Yuchun Wang, Jun-Sheng Yu, Yingqiu Liang, Kunyi Ni, Shuzi Tu. The interaction of human serum albumin with a novel antidiabetic agent--SU-118. Journal of pharmaceutical sciences. 2004 Apr; 93(4):1039-46. doi: 10.1002/jps.20005. [PMID: 14999739]
  • Keisuke Nakajou, Hiroshi Watanabe, Ulrich Kragh-Hansen, Toru Maruyama, Masaki Otagiri. The effect of glycation on the structure, function and biological fate of human serum albumin as revealed by recombinant mutants. Biochimica et biophysica acta. 2003 Oct; 1623(2-3):88-97. doi: 10.1016/j.bbagen.2003.08.001. [PMID: 14572906]
  • Peter Caravan, Normand J Cloutier, Matthew T Greenfield, Sarah A McDermid, Stephen U Dunham, Jeff W M Bulte, John C Amedio, Richard J Looby, Ronald M Supkowski, William DeW Horrocks, Thomas J McMurry, Randall B Lauffer. The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates. Journal of the American Chemical Society. 2002 Mar; 124(12):3152-62. doi: 10.1021/ja017168k. [PMID: 11902904]
  • P Caravan, M T Greenfield, X Li, A D Sherry. The Gd(3+) complex of a fatty acid analogue of DOTP binds to multiple albumin sites with variable water relaxivities. Inorganic chemistry. 2001 Dec; 40(26):6580-7. doi: 10.1021/ic0102900. [PMID: 11735466]
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  • V T Chuang, M Otagiri. Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin. Biochimica et biophysica acta. 2001 Apr; 1546(2):337-45. doi: 10.1016/s0167-4838(01)00151-0. [PMID: 11295439]
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  • S Zhou, J W Paxton, P Kestell, M D Tingle. Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species. The Journal of pharmacy and pharmacology. 2001 Apr; 53(4):463-71. doi: 10.1211/0022357011775758. [PMID: 11341362]
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