Alanyltyrosine (BioDeep_00000017792)
human metabolite Endogenous
代谢物信息卡片
化学式: C12H16N2O4 (252.111)
中文名称: 丙氨酰-L-酪氨酸
谱图信息:
最多检出来源 Homo sapiens(feces) 84.19%
分子结构信息
SMILES: CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)N
InChI: InChI=1S/C12H16N2O4/c1-7(13)11(16)14-10(12(17)18)6-8-2-4-9(15)5-3-8/h2-5,7,10,15H,6,13H2,1H3,(H,14,16)(H,17,18)
描述信息
Alanyltyrosine is a dipeptide composed of alanine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
同义名列表
19 个代谢物同义名
(2S)-2-[(2S)-2-aminopropanamido]-3-(4-hydroxyphenyl)propanoic acid; Alanyltyrosine, (N-beta-ala-L-tyr)-isomer; Alanine-tyrosine dipeptide; Alanine tyrosine dipeptide; N-L-Alanyl-L-tyrosine; beta-Alanyl-tyrosine; L-Alanyl-L-tyrosine; N-Alanyltyrosine; Alanyl-tyrosine; Alanyltyrosine; a-Y dipeptide; H-Ala-Tyr-OH; AY dipeptide; Sarcophagine; L-Ala-L-tyr; Ala-tyr; A-Y; AY; Ala-Tyr
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:174328
- ChEBI: CHEBI:73395
- PubChem: 572319
- PubChem: 92946
- HMDB: HMDB0028699
- ChEMBL: CHEMBL94016
- foodb: FDB111756
- chemspider: 83903
- CAS: 19659-02-0
- CAS: 3061-88-9
- PMhub: MS000000271
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ewelina Jamróz, Piotr Kulawik, Joanna Tkaczewska, Paulina Guzik, Marzena Zając, Lesław Juszczak, Paweł Krzyściak, Katarzyna Turek. The effects of active double-layered furcellaran/gelatin hydrolysate film system with Ala-Tyr peptide on fresh Atlantic mackerel stored at -18 °C.
Food chemistry.
2021 Feb; 338(?):127867. doi:
10.1016/j.foodchem.2020.127867
. [PMID: 32829293] - Z Zhang, Y Zhao, X Wang, R Lin, Y Zhang, H Ma, Y Guo, L Xu, B Zhao. The novel dipeptide Tyr-Ala (TA) significantly enhances the lifespan and healthspan of Caenorhabditis elegans.
Food & function.
2016 Apr; 7(4):1975-84. doi:
10.1039/c5fo01302j
. [PMID: 26987062] - Zari Hooshyar, Ghasem Rezanejade Bardajee, Nahaleh Kakavand, Mohaddeseh Khanjari, Nastaran Dianatnejad. Investigations on the interactions of DiAmsar with serum albumins: Insights from spectroscopic and molecular docking techniques.
Luminescence : the journal of biological and chemical luminescence.
2015 Aug; 30(5):538-48. doi:
10.1002/bio.2773
. [PMID: 25311912] - Jason L J Dearling, Brett M Paterson, Vamsidhar Akurathi, Soledad Betanzos-Lara, S Ted Treves, Stephan D Voss, Jonathan M White, James S Huston, Suzanne V Smith, Paul S Donnelly, Alan B Packard. The ionic charge of copper-64 complexes conjugated to an engineered antibody affects biodistribution.
Bioconjugate chemistry.
2015 Apr; 26(4):707-17. doi:
10.1021/acs.bioconjchem.5b00049
. [PMID: 25719414] - Claus G Krenn, Herwig Pokorny, Klaus Hoerauf, Josef Stark, Erich Roth, Heinz Steltzer, Wilfred Druml. Non-isotopic tyrosine kinetics using an alanyl-tyrosine dipeptide to assess graft function in liver transplant recipients - a pilot study.
Wiener klinische Wochenschrift.
2008; 120(1-2):19-24. doi:
10.1007/s00508-007-0908-y
. [PMID: 18239987] - Ioanna Kyrikou, Nikolas P Benetis, Petros Chatzigeorgiou, Maria Zervou, Kyriakos Viras, Constantine Poulos, Thomas Mavromoustakos. Interactions of the dipeptide paralysin beta-Ala-Tyr and the aminoacid Glu with phospholipid bilayers.
Biochimica et biophysica acta.
2008 Jan; 1778(1):113-24. doi:
10.1016/j.bbamem.2007.09.019
. [PMID: 17964279] - W Druml, W Hübl, E Roth, H Lochs. Utilization of tyrosine-containing dipeptides and N-acetyl-tyrosine in hepatic failure.
Hepatology (Baltimore, Md.).
1995 Apr; 21(4):923-8. doi:
NULL
. [PMID: 7705801]