Cys-phe-phe-D-trp-lys-thr-phe-D-cys (BioDeep_00000177855)

   

human metabolite blood metabolite


代谢物信息卡片


2-[(2-{[2-({6-amino-2-[(2-{[2-({2-[(2-amino-1-hydroxy-3-sulphanylpropylidene)amino]-1-hydroxy-3-phenylpropylidene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-(1H-indol-3-yl)propylidene)amino]-1-hydroxyhexylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxy-3-phenylpropylidene)amino]-3-sulphanylpropanoic acid

化学式: C54H68N10O10S2 (1080.4561068)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CS)C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CS)N)O
InChI: InChI=1S/C54H68N10O10S2/c1-32(65)46(53(72)62-43(27-35-19-9-4-10-20-35)51(70)63-45(31-76)54(73)74)64-48(67)40(23-13-14-24-55)58-52(71)44(28-36-29-57-39-22-12-11-21-37(36)39)61-50(69)42(26-34-17-7-3-8-18-34)60-49(68)41(59-47(66)38(56)30-75)25-33-15-5-2-6-16-33/h2-12,15-22,29,32,38,40-46,57,65,75-76H,13-14,23-28,30-31,55-56H2,1H3,(H,58,71)(H,59,66)(H,60,68)(H,61,69)(H,62,72)(H,63,70)(H,64,67)(H,73,74)

描述信息

同义名列表

5 个代谢物同义名

2-[(2-{[2-({6-amino-2-[(2-{[2-({2-[(2-amino-1-hydroxy-3-sulphanylpropylidene)amino]-1-hydroxy-3-phenylpropylidene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-(1H-indol-3-yl)propylidene)amino]-1-hydroxyhexylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxy-3-phenylpropylidene)amino]-3-sulphanylpropanoic acid; 2-[(2-{[2-({6-amino-2-[(2-{[2-({2-[(2-amino-1-hydroxy-3-sulphanylpropylidene)amino]-1-hydroxy-3-phenylpropylidene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-(1H-indol-3-yl)propylidene)amino]-1-hydroxyhexylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxy-3-phenylpropylidene)amino]-3-sulphanylpropanoate; 2-[(2-{[2-({6-amino-2-[(2-{[2-({2-[(2-amino-1-hydroxy-3-sulfanylpropylidene)amino]-1-hydroxy-3-phenylpropylidene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1-hydroxy-3-(1H-indol-3-yl)propylidene)amino]-1-hydroxyhexylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxy-3-phenylpropylidene)amino]-3-sulfanylpropanoate; 2-(2-{2-[6-amino-2-(2-{2-[2-(2-amino-3-sulfanylpropanamido)-3-phenylpropanamido]-3-phenylpropanamido}-3-(1H-indol-3-yl)propanamido)hexanamido]-3-hydroxybutanamido}-3-phenylpropanamido)-3-sulfanylpropanoic acid; Cys-phe-phe-D-trp-lys-thr-phe-D-cys



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • A Stengel, M Goebel-Stengel, L Wang, A Luckey, E Hu, J Rivier, Y Taché. Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2011 Jul; 23(7):e294-308. doi: 10.1111/j.1365-2982.2011.01721.x. [PMID: 21569179]
  • Miriam Goebel, Andreas Stengel, Lixin Wang, Tamer Coskun, Jorge Alsina-Fernandez, Jean Rivier, Yvette Taché. Pattern of Fos expression in the brain induced by selective activation of somatostatin receptor 2 in rats. Brain research. 2010 Sep; 1351(?):150-164. doi: 10.1016/j.brainres.2010.07.024. [PMID: 20637739]
  • Andreas Stengel, Tamer Coskun, Miriam Goebel, Lixin Wang, Libbey Craft, Jorge Alsina-Fernandez, Jean Rivier, Yvette Taché. Central injection of the stable somatostatin analog ODT8-SST induces a somatostatin2 receptor-mediated orexigenic effect: role of neuropeptide Y and opioid signaling pathways in rats. Endocrinology. 2010 Sep; 151(9):4224-35. doi: 10.1210/en.2010-0195. [PMID: 20610566]
  • P D Miles, K Yamatani, M R Brown, H L Lickley, M Vranic. Intracerebroventricular administration of somatostatin octapeptide counteracts the hormonal and metabolic responses to stress in normal and diabetic dogs. Metabolism: clinical and experimental. 1994 Sep; 43(9):1134-43. doi: 10.1016/0026-0495(94)90056-6. [PMID: 7916119]
  • M R Brown. Central nervous system sites of action of bombesin and somatostatin to influence plasma epinephrine levels. Brain research. 1983 Oct; 276(2):253-7. doi: 10.1016/0006-8993(83)90732-1. [PMID: 6138126]
  • A Buchs, F Märki, U Keller. Effect of somatostatin and two of its analogues on basal and arginine-stimulated insulin and glucagon secretion in the dog. Regulatory peptides. 1982 Aug; 4(3):117-26. doi: 10.1016/0167-0115(82)90079-9. [PMID: 6127755]
  • A J Barnes, R G Long, T E Adrian, W Vale, M R Brown, J E Rivier, J Hanley, M A Ghatei, D L Sarson, S R Bloom. Effect of a long-acting octapeptide analogue of somatostatin on growth hormone and pancreatic and gastrointestinal hormones in man. Clinical science (London, England : 1979). 1981 Nov; 61(5):653-6. doi: 10.1042/cs0610653. [PMID: 6116553]
  • D A Fisher, M R Brown. Somatostatin analog: plasma catecholamine suppression mediated by the central nervous system. Endocrinology. 1980 Sep; 107(3):714-8. doi: 10.1210/endo-107-3-714. [PMID: 6105069]