3,7-Dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide (BioDeep_00000177747)
human metabolite blood metabolite
代谢物信息卡片
化学式: C20H29NO (299.2249024)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(N)=O
InChI: InChI=1S/C20H29NO/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H2,21,22)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Parameswaran G Sreekumar, Ram Kannan, Mizuki Kitamura, Christine Spee, Ernesto Barron, Stephen J Ryan, David R Hinton. αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells.
PloS one.
2010 Oct; 5(10):e12578. doi:
10.1371/journal.pone.0012578. [PMID: 20949024] - S Karmakar, S Roy Choudhury, N L Banik, S K Ray. Combination of N-(4-hydroxyphenyl) retinamide and genistein increased apoptosis in neuroblastoma SK-N-BE2 and SH-SY5Y xenografts.
Neuroscience.
2009 Sep; 163(1):286-95. doi:
10.1016/j.neuroscience.2009.06.037. [PMID: 19540315] - Ling Cao, Peng-cheng Ma, Wen-ying Liu, Li Ding, Di Sun, Qian Yang, Feng Zheng, Peng Yu, Tai-jun Hang, Bin Di, Yu Wang. Quantitative determination and pharmacokinetics of retinamido-ester in rat plasma by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.
Yao xue xue bao = Acta pharmaceutica Sinica.
2008 Oct; 43(10):1040-6. doi:
NULL. [PMID: 19127869] - Justyna Szumiło. [Chemoprevention of esophageal squamous cell carcinoma--clinical trials].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.
2008 Sep; 25(147):280-3. doi:
". [PMID: 19112850] - Dimitrios G Fatouros, Ditte M Karpf, Flemming S Nielsen, Anette Mullertz. Clinical studies with oral lipid based formulations of poorly soluble compounds.
Therapeutics and clinical risk management.
2007 Aug; 3(4):591-604. doi:
". [PMID: 18472981] - Zeynep Ates-Alagoz, Tulay Coban, Erdem Buyukbingol. Synthesis and antioxidant activity of new tetrahydro-naphthalene-indole derivatives as retinoid and melatonin analogs.
Archiv der Pharmazie.
2006 Apr; 339(4):193-200. doi:
10.1002/ardp.200500177. [PMID: 16572477] - Da-ming Zou, Molly Brewer, Francisco Garcia, Jean M Feugang, Jian Wang, Roungyu Zang, Huaguang Liu, Changping Zou. Cactus pear: a natural product in cancer chemoprevention.
Nutrition journal.
2005 Sep; 4(?):25. doi:
10.1186/1475-2891-4-25. [PMID: 16150152] - Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2005 Jul; 46(1):e11-4. doi:
10.1053/j.ajkd.2005.03.009. [PMID: 15983949] - Hye-Sook Han, Youn-Ja Kwon, Si-Ho Park, Eun-Joo Kim, Young-Soy Rho, Hong-Sig Sin, Soo-Jong Um. Potent effect of 5-HPBR, a butanoate derivative of 4-HPR, on cell growth and apoptosis in cancer cells.
International journal of cancer.
2004 Mar; 109(1):58-64. doi:
10.1002/ijc.11643. [PMID: 14735468] - Jason S Chapman, Kevin L Weiss, Robert W Curley, Margaret A Highland, Margaret Clagett-Dame. Hydrolysis of 4-HPR to atRA occurs in vivo but is not required for retinamide-induced apoptosis.
Archives of biochemistry and biophysics.
2003 Nov; 419(2):234-43. doi:
10.1016/j.abb.2003.09.001. [PMID: 14592467] - Soo-Jong Um, Hong-Sig Sin, Hye-Sook Han, Youn-Ja Kwon, Eun-Joo Kim, Si-Ho Park, Sun-Young Kim, Tae-Sung Bae, Jong-Sup Park, Young-Soy Rho. Potent cytotoxic effects of novel retinamide derivatives in ovarian cancer cells.
Biological & pharmaceutical bulletin.
2003 Oct; 26(10):1412-7. doi:
10.1248/bpb.26.1412. [PMID: 14519946] - Anita L Sabichi, Manual R Modiano, J Jack Lee, Yei-Mei Peng, Ming-Jing Xu, Hugo Villar, William S Dalton, Scott M Lippman. Breast tissue accumulation of retinamides in a randomized short-term study of fenretinide.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2003 Jul; 9(7):2400-5. doi:
NULL. [PMID: 12855611] - A Asumendi, M C Morales, A Alvarez, J Aréchaga, G Pérez-Yarza. Implication of mitochondria-derived ROS and cardiolipin peroxidation in N-(4-hydroxyphenyl)retinamide-induced apoptosis.
British journal of cancer.
2002 Jun; 86(12):1951-6. doi:
10.1038/sj.bjc.6600356. [PMID: 12085192] - S Y Sun, P Yue, G J Kelloff, V E Steele, S M Lippman, W K Hong, R Lotan. Identification of retinamides that are more potent than N-(4-hydroxyphenyl)retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2001 Jun; 10(6):595-601. doi:
NULL. [PMID: 11401908]