2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-methyl ester;benzenesulfonic acid (BioDeep_00000177488)
human metabolite blood metabolite
代谢物信息卡片
2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-methyl ester;benzenesulphonic acid
化学式: C20H25ClN2O5 (408.1452)
中文名称:
谱图信息:
最多检出来源 not specific(not specific) 0%
分子结构信息
SMILES: CCOC(=O)C1=C(COCCN)N=C(C)C(C1C1=CC=CC=C1Cl)C(=O)OC
InChI: InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,16-17H,4,9-11,22H2,1-3H3
描述信息
同义名列表
8 个代谢物同义名
2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-methyl ester;benzenesulphonic acid; 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-methyl ester;benzenesulfonic acid; 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate O3-ethyl ester O5-methyl ester;benzenesulphonate; 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate O3-ethyl ester O5-methyl ester;benzenesulfonate; 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-methyl ester; 5-Ethyl 3-methyl 6-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-2-methyl-3,4-dihydropyridine-3,5-dicarboxylic acid; 5-ethyl 3-methyl 6-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-2-methyl-3,4-dihydropyridine-3,5-dicarboxylate; 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-4,5-dihydropyridine-3,5-dicarboxylate
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
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Journal of pharmaceutical and biomedical analysis.
2012 Dec; 71(?):104-10. doi:
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Journal of human hypertension.
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Journal of pharmaceutical and biomedical analysis.
2012 Nov; 70(?):614-8. doi:
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Transplantation proceedings.
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Cellular signalling.
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Hypertension research : official journal of the Japanese Society of Hypertension.
2012 Aug; 35(8):874-81. doi:
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Cardiovascular therapeutics.
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Electrophoresis.
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Current pharmaceutical biotechnology.
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Blood pressure.
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2012 Jul; 60(1):8-14. doi:
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Clinical therapeutics.
2012 Jul; 34(7):1625-35. doi:
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Expert opinion on pharmacotherapy.
2012 Jul; 13(10):1515-26. doi:
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Advances in therapy.
2012 Jul; 29(7):635-44. doi:
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Kidney international.
2012 Jul; 82(1):26-33. doi:
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American journal of hypertension.
2012 Jun; 25(6):704-10. doi:
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Clinical journal of the American Society of Nephrology : CJASN.
2012 Jun; 7(6):989-1002. doi:
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Journal of geriatric cardiology : JGC.
2012 Jun; 9(2):185-91. doi:
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Indian journal of endocrinology and metabolism.
2012 May; 16(3):457-9. doi:
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Hypertension (Dallas, Tex. : 1979).
2012 May; 59(5):926-33. doi:
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Pharmacogenetics and genomics.
2012 May; 22(5):355-66. doi:
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Transplantation.
2012 Apr; 93(7):e29-30. doi:
10.1097/tp.0b013e318249b180. [PMID: 22450597] - Juscelino Tovar, Anne Nilsson, Maria Johansson, Rickard Ekesbo, Ann-Margreth Aberg, Ulla Johansson, Inger Björck. A diet based on multiple functional concepts improves cardiometabolic risk parameters in healthy subjects.
Nutrition & metabolism.
2012 Apr; 9(?):29. doi:
10.1186/1743-7075-9-29. [PMID: 22472183] - Tatsuo Hosoya, Satoru Kuriyama, Iwao Ohno, Tetsuya Kawamura, Makoto Ogura, Masato Ikeda, Masahiro Ishikawa, Fumihiro Hayashi, Tatsuya Kanai, Haruo Tomonari, Michimasa Soejima, Kiyoaki Akaba, Goro Tokudome, S Endo, A Fukui, H Gomi, A Hamaguchi, K Hanaoka, Y Hara, Y Hara, T Hasegawa, H Hayakawa, M Hikida, K Hirano, M Horiguchi, M Hosoya, K Ichida, T Imai, T Ishii, H Ishikawa, C Kameda, T Kasai, A Kobayashi, H Kobayashi, M Kurashige, Y Kusama, H Maezawa, Y Maezawa, Y Maruyama, H Matsuda, N Matsuo, T Matsuo, Y Miura, M Miyajima, M Miyakawa, Y Miyazaki, M Mizuguchi, M Nakao, H Nokano, I Ohkido, Y Ohtsuka, K Okada, H Okamoto, H Okonogi, H Saikawa, H Saito, C Sekiguchi, Y Suetsugu, N Sugano, T Suzuki, T Suzuki, H Takahashi, Y Takahashi, S Takamizawa, K Takane, T Morita, K Takazoe, H Tanaka, S Tanaka, H Terawaki, R Toyoshima, N Tsuboi, T Udagawa, H Ueda, Y Ueda, M Uetake, S Unemura, M Utsunomiya, Y Utsunomiya, T Yamada, Y Yamada, Y Yamaguchi, H Yamamoto, T Yokoo, K Yokoyama, H Yonezawa, H Yoshida, M Yoshida, T Yoshizawa. Antihypertensive effect of a fixed-dose combination of losartan/hydrochlorothiazide in patients with uncontrolled hypertension: a multicenter study.
Clinical and experimental nephrology.
2012 Apr; 16(2):269-78. doi:
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2012 Apr; 12(2):137-42. doi:
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Korean circulation journal.
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Journal of human hypertension.
2012 Apr; 26(4):214-9. doi:
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American heart journal.
2012 Apr; 163(4):735-40. doi:
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Clinical and experimental nephrology.
2012 Apr; 16(2):279-91. doi:
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Diabetes, obesity & metabolism.
2012 Apr; 14(4):341-7. doi:
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Blood pressure.
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Pharmacognosy research.
2012 Apr; 4(2):92-103. doi:
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2012 Mar; 18(5):1415-25. doi:
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Clinical pharmacokinetics.
2012 Mar; 51(3):147-62. doi:
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Hypertension research : official journal of the Japanese Society of Hypertension.
2012 Mar; 35(3):348-55. doi:
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Journal of cardiovascular pharmacology and therapeutics.
2012 Mar; 17(1):34-43. doi:
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Journal of fluorescence.
2012 Mar; 22(2):549-56. doi:
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Indian journal of endocrinology and metabolism.
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Kidney international.
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Yonsei medical journal.
2012 Mar; 53(2):294-303. doi:
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Journal of cardiovascular pharmacology.
2012 Mar; 59(3):281-7. doi:
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Journal of hypertension.
2012 Mar; 30(3):561-6. doi:
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Acta pharmaceutica (Zagreb, Croatia).
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High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension.
2012 Mar; 19(1):19-31. doi:
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Circulation. Cardiovascular quality and outcomes.
2012 Mar; 5(2):153-62. doi:
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Hypertension research : official journal of the Japanese Society of Hypertension.
2012 Feb; 35(2):221-7. doi:
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European journal of gastroenterology & hepatology.
2012 Feb; 24(2):164-71. doi:
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Journal of medicinal food.
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