2-Chloroacetamide (BioDeep_00000177393)

   

human metabolite blood metabolite PANOMIX_OTCML-2023


代谢物信息卡片


2-chloroethanimidic acid

化学式: C2H4ClNO (92.99814040000001)
中文名称: 氯乙酰胺
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 82.61%

分子结构信息

SMILES: C(C(=O)N)Cl
InChI: InChI=1S/C2H4ClNO/c3-1-2(4)5/h1H2,(H2,4,5)

描述信息

2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase[1][2][3].

同义名列表

6 个代谢物同义名

2-chloroethanimidic acid; 2-Chloroethanimidate; 2-chloro-Acetamide; 2-Chloroacetamide; Chloroacetamide; Chloracetamide



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shao-Fang Chen, Wen-Juan Chen, Yaohua Huang, Ming Wei, Changqing Chang. Insights into the metabolic pathways and biodegradation mechanisms of chloroacetamide herbicides. Environmental research. 2023 07; 229(?):115918. doi: 10.1016/j.envres.2023.115918. [PMID: 37062473]
  • Koji Kosaka, Azusa Iwatani, Yuuki Takeichi, Yusuke Yoshikawa, Keiko Ohkubo, Michihiro Akiba. Removal of haloacetamides and their precursors at water purification plants applying ozone/biological activated carbon treatment. Chemosphere. 2018 May; 198(?):68-74. doi: 10.1016/j.chemosphere.2018.01.093. [PMID: 29421762]
  • Michael Obermeier, Christian A Schröder, Brigitte Helmreich, Peter Schröder. The enzymatic and antioxidative stress response of Lemna minor to copper and a chloroacetamide herbicide. Environmental science and pollution research international. 2015 Dec; 22(23):18495-507. doi: 10.1007/s11356-015-5139-6. [PMID: 26286797]
  • Tae Hwan Kim, Su Hyun Seok, Kyu-Bong Kim, Beom Soo Shin, Jeong Pyo Lee, Yong-Kyu Choi, Min Gi Kim, Min Kyu Kim, Sang Min Kim, Sun Dong Yoo. LC-APCI-MS/MS Quantification and Topical Bioavailability of Chloroacetamide in Rats. Journal of chromatographic science. 2015 Aug; 53(7):1100-6. doi: 10.1093/chromsci/bmu172. [PMID: 25523464]
  • Qing Chen, Jun Zhang, Cheng-Hong Wang, Jin Jiang, Soon-Wo Kwon, Li-Na Sun, Wen-Biao Shen, Jian He. Novosphingobium chloroacetimidivorans sp. nov., a chloroacetamide herbicide-degrading bacterium isolated from activated sludge. International journal of systematic and evolutionary microbiology. 2014 Aug; 64(Pt 8):2573-2578. doi: 10.1099/ijs.0.062950-0. [PMID: 24814333]
  • Joanna Bernasinska, Piotr Duchnowicz, Maria Koter-Michalak, Aneta Koceva-Chyla. Effect of safeners on damage of human erythrocytes treated with chloroacetamide herbicides. Environmental toxicology and pharmacology. 2013 Sep; 36(2):368-377. doi: 10.1016/j.etap.2013.04.010. [PMID: 23732483]
  • Stéphane Bouchonnet, Sophie Bourcier, Yasmine Souissi, Christophe Genty, Michel Sablier, Pascal Roche, Véronique Boireau, Valérie Ingrand. GC-MS(n) and LC-MS/MS couplings for the identification of degradation products resulting from the ozonation treatment of Acetochlor. Journal of mass spectrometry : JMS. 2012 Apr; 47(4):439-52. doi: 10.1002/jms.2056. [PMID: 22689619]
  • Dirk M Walther, Matthias Mann. Accurate quantification of more than 4000 mouse tissue proteins reveals minimal proteome changes during aging. Molecular & cellular proteomics : MCP. 2011 Feb; 10(2):M110.004523. doi: 10.1074/mcp.m110.004523. [PMID: 21048193]
  • Sakiko Hirose, Hiroyuki Kawahigashi, Akemi Tagiri, Yasunobu Ohkawa. Herbicide-induced anthocyanin accumulation in transgenic rice by expression of rice OSB2 under the control of rice CYP72A21 promoter. Journal of agricultural and food chemistry. 2008 Feb; 56(4):1259-63. doi: 10.1021/jf071575j. [PMID: 18217708]
  • Gino Serra, Walter Fratta. A possible role for the endocannabinoid system in the neurobiology of depression. Clinical practice and epidemiology in mental health : CP & EMH. 2007 Nov; 3(?):25. doi: 10.1186/1745-0179-3-25. [PMID: 18021439]
  • Ben P DeRidder, Peter B Goldsbrough. Organ-specific expression of glutathione S-transferases and the efficacy of herbicide safeners in Arabidopsis. Plant physiology. 2006 Jan; 140(1):167-75. doi: 10.1104/pp.105.067199. [PMID: 16361527]
  • Sakiko Hirose, Hiroyuki Kawahigashi, Kenjirou Ozawa, Noriaki Shiota, Hideyuki Inui, Hideo Ohkawa, Yasunobu Ohkawa. Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides. Journal of agricultural and food chemistry. 2005 May; 53(9):3461-7. doi: 10.1021/jf050064z. [PMID: 15853388]
  • Nadia Efremova, Lukas Schreiber, Sascha Bär, Iris Heidmann, Peter Huijser, Kirsten Wellesen, Zsuzsanna Schwarz-Sommer, Heinz Saedler, Alexander Yephremov. Functional conservation and maintenance of expression pattern of FIDDLEHEAD-like genes in Arabidopsis and Antirrhinum. Plant molecular biology. 2004 Nov; 56(5):821-37. doi: 10.1007/s11103-004-5576-y. [PMID: 15803418]
  • Thomas Götz, Peter Böger. The very-long-chain fatty acid synthase is inhibited by chloroacetamides. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2004 Jul; 59(7-8):549-53. doi: 10.1515/znc-2004-7-818. [PMID: 15813378]
  • Christian Eckermann, Bernd Matthes, Manfred Nimtz, Verena Reiser, Barbara Lederer, Peter Böger, Joachim Schröder. Covalent binding of chloroacetamide herbicides to the active site cysteine of plant type III polyketide synthases. Phytochemistry. 2003 Nov; 64(6):1045-54. doi: 10.1016/s0031-9422(03)00516-8. [PMID: 14568070]
  • Robert A McKelvey, John P Wright, Joy L Honegger. A comparison of crop and non-crop plants as sensitive indicator species for regulatory testing. Pest management science. 2002 Dec; 58(12):1161-74. doi: 10.1002/ps.504. [PMID: 12476989]
  • Bernd Matthes, Peter Böger. Chloroacetamides affect the plasma membrane. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2002 Sep; 57(9-10):843-52. doi: 10.1515/znc-2002-9-1015. [PMID: 12440722]
  • T C Mueller, S A Senseman, K H Carson, A S Sciumbato. Stability and recovery of triazine and chloroacetamide herbicides from pH adjusted water samples by using empore solid-phase extraction disks and gas chromatography with ion trap mass spectrometry. Journal of AOAC International. 2001 Jul; 84(4):1070-3. doi: 10.1093/jaoac/84.4.1070. [PMID: 11501907]
  • A C de Groot, J W Weyland. Contact allergy to chloroacetamide in an 'anti-wrinkle serum'. Contact dermatitis. 1986 Aug; 15(2):97-8. doi: 10.1111/j.1600-0536.1986.tb01290.x. [PMID: 3780211]
  • J L Cluet, C Boudène. [Effects of organohalogenated compounds on the emission of ethane and pentane in expired air]. Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie. 1983; 296(6):275-8. doi: ". [PMID: 6405989]
  • I Anundi, J Rajs, J Högberg. Chloroacetamide hepatotoxicity: hydropic degeneration and lipid peroxidation. Toxicology and applied pharmacology. 1980 Sep; 55(2):273-80. doi: 10.1016/0041-008x(80)90089-7. [PMID: 7423517]